Protective effects of cyclooxygenase-2 inhibitors on narrow-band ultraviolet B-irradiated epidermal Ia+ Langerhans cells and Thy-1+ dendritic epidermal T cells in mice.

Abstract:

:Cyclooxygenase (COX)-2 inhibitors are known to be used as chemopreventative agents against certain malignancies. Thus far, there has been very limited information on whether COX-2 inhibitors protect against chronic narrow-band UVB (NB-UVB)-induced immunosuppression. The present study investigated the effect of nonselective and specific COX-2 inhibitors, indomethacin and celecoxib, on epidermal Ia+ Langerhans cells (LCs) and Thy-1+ dendritic epidermal T cells (DETCs) in mice irradiated with NB-UVB. Sixty female BALB/c mice were divided randomly into the control group (sham) and the experimental groups (irradiated with NB-UVB for 17 weeks, further divided into five groups according to the diets containing different concentrations of either COX-2 inhibitors). Alterations in the density and morphology of epidermal Ia+ LCs and Thy-1+ DETCs in mice were documented using fluorescence microscopy. Chronic NB-UVB irradiation substantially decreased the density and altered the morphology of the epidermal Ia+ LCs and Thy-1+ DETCs in control mice. The dietary supplementation of both COX-2 inhibitors displayed a dosage-dependent protective effect on the murine dendritic cells irradiated by NB-UVB. In conclusion, COX-2 inhibitors protected against chronic NB-UVB-induced density and morphologic changes in epidermal Ia+ LCs and Thy-1+ DETCs in mice.

journal_name

Photochem Photobiol

authors

Wu Y,Tai CL,Wei H,He F,Wang Y,Zhao Y,Chen HD

doi

10.1111/j.1751-1097.2007.00289.x

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

484-8

issue

2

eissn

0031-8655

issn

1751-1097

pii

PHP289

journal_volume

84

pub_type

杂志文章
  • Comparisons of photo-fries rearrangements of 4-dodecylphenyl phenylacetate and two structurally related esters in hexane and polyethylene cages. How important are anchoring chains?

    abstract::Photo-Fries rearrangements of 4-dodecylphenyl phenylacetate have been investigated in polyethylene films with 0-71% crystallinity and in hexane over a range of temperatures. The results are compared to those reported previously from phenyl phenylacetate and 1-naphthyl tetradecanoate to assess the influence of a long a...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/2005-05-26-RA-546

    authors: Luo C,Passin P,Weiss RG

    更新日期:2006-01-01 00:00:00

  • Lethal Effect of Photodynamic Treatment on Persister Bacteria.

    abstract::Persister bacteria tolerate bactericidal antibiotics due to transient and reversible phenotypic changes. As these bacteria can limit the effectiveness of antibiotics to eradicate certain infections, their elimination is a relevant issue. Photodynamic therapy seems suitable for this purpose, but phenotypic tolerance to...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12843

    authors: Oppezzo OJ,Forte Giacobone AF

    更新日期:2018-01-01 00:00:00

  • Daily Variation of UV-induced Erythema and the Action of Solar Filters.

    abstract::UV rays may cause several degrees of skin damage, which makes sunscreen research necessary. In addition, skin sensitivity shows daily variations, which can interfere in the detection of the efficacy of the filters. Here, we studied the UV-induced erythema in hairless rats at two times of the day (light and darkness) u...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12670

    authors: Flo A,Calpena AC,Díez-Noguera A,Del Pozo A,Cambras T

    更新日期:2017-03-01 00:00:00

  • Dye-sensitized destabilization of liposomes bearing photooxidizable lipid head groups.

    abstract::Liposomes were prepared from mixtures of dipalmitoyl-L-alpha-phosphatidylcholine and up to 40% mol:mol of N-stearoyl-L-histidine (NSH) in the presence of the hydrophobic sensitizer DHE. In the dark such liposomes are stable and retain entrapped salts. On photolysis with visible light, liposomes leak trapped ions at NS...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1993.tb09575.x

    authors: Chowdhary RK,Green CA,Morgan CG

    更新日期:1993-09-01 00:00:00

  • Estimating the Diurnal Cycle and Daily Insolation of Ultraviolet and Photosynthetically Active Radiation at the Sea Surface.

    abstract::Accurate determination of the diurnal variability and daily insolation of surface (0(+) ) and subsurface (0(-) ) irradiance are essential to estimate several physical, chemical and biological processes occurring at the surface layer of marine environments. Natural downwelling PAR and spectral UVR were examined on eigh...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12474

    authors: Kuwahara VS,Taguchi S

    更新日期:2015-09-01 00:00:00

  • Carotenohematoporphyrins as tumor-imaging dyes. Synthesis and in vitro photophysical characterization.

    abstract::Multichromophoric dyes for use in tumor imaging have been synthesized and photophysically characterized. Structurally, these dyes are dyads and triads that consist of one or two carotenoid polyenes covalently attached to hematoporphyrin (HP) or hematoporphyrin dimethyl ester (HPDME) moieties via ester linkages. The gr...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:

    authors: Tatman D,Liddell PA,Moore TA,Gust D,Moore AL

    更新日期:1998-10-01 00:00:00

  • Cancer Cell-targeted and Activatable Photoimmunotherapy Spares T Cells in a 3D Coculture Model.

    abstract::Photodynamic therapy (PDT) is an established therapeutic modality that uses nonionizing near-infrared light to activate photocytotoxicity of endogenous or exogenous photosensitizers (PSs). An ongoing avenue of cancer research involves leveraging PDT to stimulate antitumor immune responses; however, these effects appea...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13153

    authors: Kercher EM,Nath S,Rizvi I,Spring BQ

    更新日期:2020-03-01 00:00:00

  • Iodouracil as a personal dosimeter for solar UVB.

    abstract::A solution of iodouracil (0.2 mg/mL) and KI (0.1 M) in 0.23 M borate buffer (pH 7) forms triiodide upon exposure to UVB. In the presence of thyodene, the blue starch-iodine complex is formed, the intensity of which is proportional to the amount of UVB exposure. Studies were conducted using either a sunlamp or solar ir...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:

    authors: Rahn R,Lee MA

    更新日期:1998-08-01 00:00:00

  • Photoreduction and ketone-sensitized reduction of alkaloids.

    abstract::The photoprocesses of berberine, palmatine, coralyne, sanguinarine, flavopereirine and ellipticine were studied in several solvents. The quantum yields Φ(Δ) of singlet molecular oxygen formation of berberine, palmatine and sanguinarine are moderate in dichloromethane (0.2-0.6) and much smaller in acetonitrile or trifl...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2010.00880.x

    authors: Görner H,Miskolczy Z,Megyesi M,Biczók L

    更新日期:2011-03-01 00:00:00

  • Daily duration of vitamin D synthesis in human skin with relation to latitude, total ozone, altitude, ground cover, aerosols and cloud thickness.

    abstract::Vitamin D production in human skin occurs only when incident UV radiation exceeds a certain threshold. From simulations of UV irradiances worldwide and throughout the year, we have studied the dependency of the extent and duration of cutaneous vitamin D production in terms of latitude, time, total ozone, clouds, aeros...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/2004-11-19-RN-375

    authors: Engelsen O,Brustad M,Aksnes L,Lund E

    更新日期:2005-11-01 00:00:00

  • Induction of systemic neutrophil response in mice by photodynamic therapy of solid tumors.

    abstract::Photodynamic therapy (PDT) of solid tumors elicits a strong, acute inflammatory response characterized by a rapid and massive infiltration of activated neutrophils into the tumor. The present study investigated the impact of PDT on the systemic and local (treatment site) kinetics of neutrophil trafficking and activity...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2001)074<0712:iosnri>2.0.co;2

    authors: Cecic I,Parkins CS,Korbelik M

    更新日期:2001-11-01 00:00:00

  • Chlorophyll fluorescence imaging for the noninvasive assessment of anthocyanins in whole grape (Vitis vinifera L.) bunches.

    abstract::The distribution of anthocyanins in grape (Vitis vinifera L.) bunches from the Sangiovese cultivar was measured nondestructively by chlorophyll fluorescence imaging using two excitation light bands at 550 and 650 nm in sequence. The pixel intensity in the derived logarithm of the fluorescence excitation ratio image wa...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2008.00424.x

    authors: Agati G,Traversi ML,Cerovic ZG

    更新日期:2008-11-01 00:00:00

  • Light emission accompanies oxygen uptake during the peroxidative metabolism of tetracyclines.

    abstract::Tetracycline molecules offer several sites for peroxidative metabolism of the type known to lead to oxygen consumption and electronic excitation. Accordingly, when tetracycline and chlortetracycline were exposed to horseradish peroxidase in the presence of hydrogen peroxide, oxygen was taken up and light emission was ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1993.tb09588.x

    authors: Gilio VE,Cilento G

    更新日期:1993-09-01 00:00:00

  • Magnetic resonance imaging evaluation of photodynamic therapy-induced hemorrhagic necrosis in the murine M1 tumor model.

    abstract::Proton magnetic resonance imaging (MRI) and histological methods were used to evaluate photodynamic therapy (PDT)-induced hemorrhagic necrosis in the murine M1 tumor within 72 h of treatment of male DBA/2 mice. The effects of three photosensitizing drugs were investigated: Photofrin (n = 4), Zn (II) phthalocyanine (n ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1997.tb03236.x

    authors: Winsborrow BG,Grondey H,Savoie H,Fyfe CA,Dolphin D

    更新日期:1997-12-01 00:00:00

  • Kinetic separation of phototropism from blue-light inhibition of stem elongation.

    abstract::These experiments tested the hypothesis that phototropic bending arises when a light gradient across the stem differentially inhibits cell elongation because of direct inhibition of cell elongation by light (the Blaauw hypothesis). Continuous irradiation of dark-grown cucumber seedlings (Cucumis sativus L.) with unil...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1985.tb01642.x

    authors: Cosgrove DJ

    更新日期:1985-01-01 00:00:00

  • Impact of Long-Wavelength Ultraviolet A1 and Visible Light on Light-Skinned Individuals.

    abstract::Solar radiation is known to be a major contributor to the development of skin cancer. Most sunscreen formulations, including those with broad spectrum, offer minimal protection in long-wavelength ultraviolet A1 (UVA1; 370-400 nm) and visible light (VL; 400-700 nm) domain. There is limited information regarding the imp...

    journal_title:Photochemistry and photobiology

    pub_type: 信件

    doi:10.1111/php.13143

    authors: Kohli I,Zubair R,Lyons AB,Nahhas AF,Braunberger TL,Mokhtari M,Ruvolo E,Lim HW,Hamzavi IH

    更新日期:2019-11-01 00:00:00

  • Photochemically induced binding of Rh(phen)2Cl2+ to DNA.

    abstract::The photoinduced covalent binding of the title compound to native and heat denatured DNA is described. The level of binding has been measured by UV (for DNA) and atomic absorption (for Rh) analysis. Quantum efficiencies of 6.4 x 10(-4) mol Rh per mol photons and 1.6 x 10(-3) mol Rh per mol photons have been determined...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1989.tb09204.x

    authors: Mahnken RE,Bina M,Deibel RM,Luebke K,Morrison H

    更新日期:1989-04-01 00:00:00

  • Light-induced carbon dioxide and oxygen uptake in plant leaves measured by the photoacoustic method.

    abstract::Leaf discs, enclosed in a photoacoustic (PA) chamber, generate two types of PA gas-uptake signals under certain conditions. Type I is manifested by a severe signal decrease that develops slowly under very low-light intensity and often reaches negative values. It is partially reversed by low-intensity far-red light. Ty...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2001)074<0593:licdao>2.0.co;2

    authors: Malkin S,Havaux M

    更新日期:2001-10-01 00:00:00

  • Attitudes, Beliefs, and Measures Taken by Parents to Protect Their Children from the Sun in Guangzhou City, China.

    abstract::Excessive sun exposure can cause sunburn, suntan, skin photoaging, and even skin cancer. Skin photoaging conflicts with the human pursuit of a young and beautiful appearance. Some research data indicate that the incidence of skin cancer in the Chinese has been increasing, although it remains lower than in whites. To e...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12623

    authors: Wan M,Hu R,Li Y,Wang Y,Xie X,Yue P,Guan L,Lai W

    更新日期:2016-09-01 00:00:00

  • From San Luis, A Few Words of Gratitude.

    abstract::The Photochemical Research Group from San Luis (Argentina) highlights the contributions of Dr. Norman Andino García to the development of the group as a way to show him our gratitude for all his support. ...

    journal_title:Photochemistry and photobiology

    pub_type: 社论

    doi:10.1111/php.12988

    authors: Ferrari G,Montaña MP

    更新日期:2018-11-01 00:00:00

  • New Perspectives on an Old Issue: A Comparative MS-CASPT2 and OM2-MRCI Study of Polyenes and Protonated Schiff Bases.

    abstract::Polyenic systems are involved in light perception of numerous living organisms. Although a π-conjugated backbone is a common feature of all polyenes, their photophysics may vary. We provide a comparative quantum mechanical study of low-lying S1 and S2 excited states in short (3-5 double bonds) symmetric all-trans line...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12833

    authors: Dokukina I,Marian CM,Weingart O

    更新日期:2017-11-01 00:00:00

  • Axially Decorated SiIV -phthalocyanines Bearing Mannose- or Ammonium-conjugated Siloxanes: Comparative Bacterial Labeling and Photodynamic Inactivation.

    abstract::Herein, we present a comparative study about the photoinactivation of Staphylococcus aureus (Gram-positive model) and Escherichia coli (Gram-negative model) employing a neutral and a dicationic axially functionalized SiIV -phthalocyanine. Depending on the charge of the siloxane moiety (neutral monosaccharide or cation...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12881

    authors: Grüner MC,Niemann S,Faust A,Strassert CA

    更新日期:2018-09-01 00:00:00

  • Simulation of ozone depletion using ambient irradiance supplemented with UV lamps.

    abstract::In studies of the biological effects of UV radiation, ozone depletion can be mimicked by performing the study under ambient conditions and adding radiation with UV-B lamps. We evaluated this methodology at three different locations along a latitudinal gradient: Rimouski (Canada), Ubatuba (Brazil) and Ushuaia (Argentin...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/2005-09-28-ra-700

    authors: Díaz S,Camilión C,Escobar J,Deferrari G,Roy S,Lacoste K,Demers S,Belzile C,Ferreyra G,Gianesella S,Gosselin M,Nozais C,Pelletier E,Schloss I,Vernet M

    更新日期:2006-07-01 00:00:00

  • The laser two-photon photolysis of liquid carbon tetrachloride.

    abstract::The two-photon photolysis of liquid CCl4 with 25 ps pulses of 266 nm light has been studied and compared with similar studies with high energy radiation. Both neutral and ionic species are produced from excited states and ionization. The emphasis of the study is on the ionic processes, while some data related to excit...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/2005-06-03-RA-563

    authors: Zhang G,Thomas JK

    更新日期:2006-01-01 00:00:00

  • Ultraviolet light induces double-strand breaks in DNA of cultured human P3 cells as measured by neutral filter elution.

    abstract::Neutral filter elution at pH 7.2 and 9.6 was used to measure the induction of DNA lesions in human P3 teratocarcinoma cells by monochromatic 254-, 270-, 313-, 334-, 365-, and 405-nm radiation and by 60 gamma rays. In this assay DNA double-strand breaks (dsb) increase the rate of elution of DNA from cell lysates on a f...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1990.tb04194.x

    authors: Peak JG,Peak MJ

    更新日期:1990-08-01 00:00:00

  • Photochemical Behavior of Some Estrone Aryl and Methyl Sulfonates in Solution: Preparative and Mechanistic Studies.

    abstract::Direct irradiation of estrone aryl and methyl sulfonates in different organic solvents under nitrogen atmosphere was investigated under steady-state conditions. The estrone derivatives reacted efficiently through the photo-Fries rearrangement reaction involving [1;3]-sulfonyl migration providing the ortho-sulfonyl est...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13272

    authors: Quindt MI,Gola GF,Ramirez JA,Bonesi SM

    更新日期:2021-01-01 00:00:00

  • Optical Spectroscopy as a Method for Skin Cancer Risk Assessment.

    abstract::Skin cancer is the most prevalent cancer, and its assessment remains a challenge for physicians. This study reports the application of an optical sensing method, elastic scattering spectroscopy (ESS), coupled with a classifier that was developed with machine learning, to assist in the discrimination of skin lesions th...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13140

    authors: Rodriguez-Diaz E,Manolakos D,Christman H,Bonning MA,Geisse JK,A'Amar OM,Leffell DJ,Bigio IJ

    更新日期:2019-11-01 00:00:00

  • Do years or quanta age the retina?

    abstract::The progressive loss of visual faculties with advancing age is attributed, sometimes, mainly to allegedly inevitable optical deterioration, such as clouding of the media, or again to neurosenescence, as typified by cell-death. The relevant factors are assessed, and it is not thought likely that changes in normal ocula...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1751-1097.1989.tb04181.x

    authors: Weale RA

    更新日期:1989-09-01 00:00:00

  • Fluorescence polarization studies of B-phycoerythrin oriented in polymer film.

    abstract::Polarized steady-state fluorescence and fluorescence excitation spectra as well as time-resolved fluorescence for B-phycoerythrin (B-PE) from red algae, Porphyridium cruentum, embedded in polyvinyl stretched films were measured. The lifetimes of polarized fluorescence were analyzed using exponential components and fra...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:

    authors: Frackowiak D,Ptak A,Gryczynski Z,Gryczynski I,Targowski P,Zelent B

    更新日期:2004-01-01 00:00:00

  • Chlorin e6 derivative radachlorin mainly accumulates in mitochondria, lysosome and endoplasmic reticulum and shows high affinity toward tumors in nude mice in photodynamic therapy.

    abstract::The efficacy of photodynamic therapy (PDT) depends upon the amount of photosensitizer accumulated in the malignant tissues. Radachlorin is a popular photosensitizer used in photodynamic therapy to treat various types of cancer. In this study, we have studied the main organelles responsible for the accumulation of rada...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12273

    authors: Biswas R,Moon JH,Ahn JC

    更新日期:2014-09-01 00:00:00