Chlorin e6 derivative radachlorin mainly accumulates in mitochondria, lysosome and endoplasmic reticulum and shows high affinity toward tumors in nude mice in photodynamic therapy.

abstract：:Light-dark cycles are considered important cues to entrain biological clocks. A feedback loop of clock gene transcription and translation is the molecular basis underlying the mechanism of both central and peripheral clocks. Xenopus laevis embryonic melanophores respond to light with melanin granule dispersion, respon...

journal_title：Photochemistry and photobiology

authors： Magalhães Moraes MN,de Oliveira Poletini M,Ribeiro Ramos BC,de Lima LH,de Lauro Castrucci AM

更新日期：2014-05-01 00:00:00

abstract：:This paper reviews briefly the evidence for an association between various measures of UV radiation (UVR) exposure and the development of cancer. Issues such as data quality, study design, measurement variation, comparability of studies, and quantification of UV exposure in relation to skin cancer are discussed. A ran...

journal_title：Photochemistry and photobiology

authors： Berwick M,Kesler D

更新日期：2005-11-01 00:00:00

abstract：:Solar radiation is known to be a major contributor to the development of skin cancer. Most sunscreen formulations, including those with broad spectrum, offer minimal protection in long-wavelength ultraviolet A1 (UVA1; 370-400 nm) and visible light (VL; 400-700 nm) domain. There is limited information regarding the imp...

journal_title：Photochemistry and photobiology

authors： Kohli I,Zubair R,Lyons AB,Nahhas AF,Braunberger TL,Mokhtari M,Ruvolo E,Lim HW,Hamzavi IH

更新日期：2019-11-01 00:00:00

abstract：:The photoprocesses of berberine, palmatine, coralyne, sanguinarine, flavopereirine and ellipticine were studied in several solvents. The quantum yields Φ(Δ) of singlet molecular oxygen formation of berberine, palmatine and sanguinarine are moderate in dichloromethane (0.2-0.6) and much smaller in acetonitrile or trifl...

journal_title：Photochemistry and photobiology

authors： Görner H,Miskolczy Z,Megyesi M,Biczók L

更新日期：2011-03-01 00:00:00

abstract：:The pyrimidine nucleobases contained in DNA undergo a variety of photoinduced reactions in which two moieties become joined to form a product (e.g. formation of cyclobutane dimers and [6-4] adducts). Herein, we describe a new type of photoconjugation reaction that has been shown to occur for 5-methylcytosine (5-MeC), ...

journal_title：Photochemistry and photobiology

authors： Shetlar MD,Chung J

更新日期：2012-03-01 00:00:00

abstract：:Neutral filter elution at pH 7.2 and 9.6 was used to measure the induction of DNA lesions in human P3 teratocarcinoma cells by monochromatic 254-, 270-, 313-, 334-, 365-, and 405-nm radiation and by 60 gamma rays. In this assay DNA double-strand breaks (dsb) increase the rate of elution of DNA from cell lysates on a f...

journal_title：Photochemistry and photobiology

authors： Peak JG,Peak MJ

更新日期：1990-08-01 00:00:00

abstract：:The cellular uptake, localization and efflux of meso-tetra-(4-hydroxyphenyl)porphyrin (p-THPP)-loaded nanoparticles have been studied in EMT-6 tumor cells. The effect of blood serum on photocytotoxicity has also been evaluated. Sub-130 nm nanoparticles based on poly(D,L-lactide-co-glycolide) (PLGA) (50:50 PLGA and 75:...

journal_title：Photochemistry and photobiology

authors： Konan YN,Chevallier J,Gurny R,Allémann E

更新日期：2003-06-01 00:00:00

abstract：:The aim of this investigation is the evaluation of DNA interaction of with tetraruthenated porphyrin (TRP) and of DNA damage in the presence of light. Direct-fluorescence and electronic absorption measurements after incubation of DNA with TRP indicate strong binding between pBR322 DNA or calf thymus DNA with the modif...

journal_title：Photochemistry and photobiology

authors： Onuki J,Ribas AV,Medeiros MH,Araki K,Toma HE,Catalani LH,Di Mascio P

更新日期：1996-03-01 00:00:00

abstract：:Confocal laser microspectrofluorometric measurements on human T47D mammary tumor cells have been performed to assess the intracellular distribution of hypericin within the various cell compartments: cytoplasmic membrane, cytoplasm and nucleus. Confocal fluorescence measurements obtained from microvolumes (approximatel...

journal_title：Photochemistry and photobiology

authors： Miskovsky P,Sureau F,Chinsky L,Turpin PY

更新日期：1995-09-01 00:00:00

abstract：:Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectanc...

journal_title：Photochemistry and photobiology

authors： Marchesini R,Brambilla M,Clemente C,Maniezzo M,Sichirollo AE,Testori A,Venturoli DR,Cascinelli N

更新日期：1991-01-01 00:00:00

abstract：:In studies of the biological effects of UV radiation, ozone depletion can be mimicked by performing the study under ambient conditions and adding radiation with UV-B lamps. We evaluated this methodology at three different locations along a latitudinal gradient: Rimouski (Canada), Ubatuba (Brazil) and Ushuaia (Argentin...

journal_title：Photochemistry and photobiology

authors： Díaz S,Camilión C,Escobar J,Deferrari G,Roy S,Lacoste K,Demers S,Belzile C,Ferreyra G,Gianesella S,Gosselin M,Nozais C,Pelletier E,Schloss I,Vernet M

更新日期：2006-07-01 00:00:00

abstract：:δ-Aminolevulinic acid (ALA)-induced porphyrin accumulation is widely used in the treatment of cancer, as photodynamic therapy. To clarify the mechanisms of the tumor-preferential accumulation of protoporphyrin, we examined the effect of the expression of heme-biosynthetic and -degradative enzymes on the ALA-induced ac...

journal_title：Photochemistry and photobiology

authors： Ohgari Y,Miyata Y,Miyagi T,Gotoh S,Ohta T,Kataoka T,Furuyama K,Taketani S

更新日期：2011-09-01 00:00:00

abstract：:The mechanism of caspase-3-dependent apoptosis induced by photodynamic therapy (PDT) of cultured Chinese hamster V79 cells with pheophorbide a (PPa) was investigated. The PPa-PDT induced rapid apoptosis within 30 min after irradiation of cells. This apoptosis was inhibited by the 1O2 quencher N3- and caspase-3 inhibit...

journal_title：Photochemistry and photobiology

authors： Inanami O,Yoshito A,Takahashi K,Hiraoka W,Kuwabara M

更新日期：1999-10-01 00:00:00

abstract：:The sequence specificity of photobinding to DNA of two tetrahydrobenzopsoralen derivatives has been investigated by testing the photoreactivity toward a number of self-complementary oligonucleotides. The thermodynamic constant for noncovalent binding to each DNA sequence was evaluated. The extent of photoreactivity wa...

journal_title：Photochemistry and photobiology

authors： Mobilio S,Tondelli L,Capobianco M,Gia O

更新日期：1995-02-01 00:00:00

abstract：:Exploration of environmental dynamics using intrinsic biological probe tryptophan is very important; however, it suffers from various difficulties. An alternative probe, kynurenine (KN), has been found to be an efficient probe for the ultrafast dynamics in the biological environment (Goswami et al., [2010] J. Phys. Ch...

journal_title：Photochemistry and photobiology

authors： Rakshit S,Goswami N,Pal SK

更新日期：2012-01-01 00:00:00

abstract：:Under continuous photolysis at 675 nm, liposomal zinc phthalocyanine associated with nitrosyl ruthenium complex [Ru(NH.NHq)(tpy)NO](3+) showed the detection and quantification of nitric oxide (NO) and singlet oxygen ((1)O(2)) release. Photophysical and photochemical results demonstrated that the interaction between th...

journal_title：Photochemistry and photobiology

authors： Maranho DS,de Lima RG,Primo FL,da Silva RS,Tedesco AC

更新日期：2009-05-01 00:00:00

abstract：:Accurate determination of the diurnal variability and daily insolation of surface (0(+) ) and subsurface (0(-) ) irradiance are essential to estimate several physical, chemical and biological processes occurring at the surface layer of marine environments. Natural downwelling PAR and spectral UVR were examined on eigh...

journal_title：Photochemistry and photobiology

authors： Kuwahara VS,Taguchi S

更新日期：2015-09-01 00:00:00

abstract：:Several spectroscopic techniques (absorption, emission, transient absorption and differential scanning calorimetry--DSC) were used to investigate the deprotonation of dibucaine.HCl in a hydrophobic environment, and the interaction sites and mechanisms of the local anesthetic dibucaine.HCl on bacteriorhodopsin (bR) in ...

journal_title：Photochemistry and photobiology

authors： Lin CT,Chyan YG,Kresheck GC,Bitting HC Jr,el-Sayed MA

更新日期：1989-05-01 00:00:00

abstract：:In horticultural crops, the use of screens to protect plants is the usual strategy in the Mediterranean area. Screen manufacturers offer a range of netting that vary in their UV-absorbing properties. We compared the photoeffects of seven different screens. Sweet pepper trials were conducted at the Gilat Research Cente...

journal_title：Photochemistry and photobiology

authors： Legarrea S,Karnieli A,Fereres A,Weintraub PG

更新日期：2010-03-01 00:00:00

abstract：:The retinal protonated Schiff base of bacteriorhodopsin is photoreactive to reducing agents such as NaBH4. In the present work we have studied the effect of different protein hydration levels on the photoreductive reaction, as well as the consequences of preventing isomerization around the critical C13=C14 retinal dou...

journal_title：Photochemistry and photobiology

authors： Aharoni A,Ottolenghi M,Sheves M

更新日期：2002-06-01 00:00:00

abstract：:The seminal discovery by James Cleaver of defective DNA repair in xeroderma pigmentosum (XP) opened up an ever-expanding field of DNA repair-related disorders. In addition, it put XP on the map and has led to improved diagnosis, care and management of affected patients. In the United Kingdom, we recently established a...

journal_title：Photochemistry and photobiology

authors： Lehmann AR

更新日期：2015-03-01 00:00:00

abstract：:The protein environments surrounding the retinal tune electronic absorption maximum from 350 to 630 nm. Hybrid quantum mechanical/molecular mechanical (QM/MM) methods can be used in calculating excitation energies of retinal in its native protein environments and in studying the molecular basis of spectral tuning. We ...

journal_title：Photochemistry and photobiology

authors： Altun A,Yokoyama S,Morokuma K

更新日期：2008-07-01 00:00:00

abstract：:The energetic characteristics of selected reaction steps in the bacterial luciferase-catalyzed luminescence reaction were examined by computation using the MNDO-PM3 method. Specifically, a three-step model was proposed to account for the reaction between oxygen and reduced riboflavin 5'-phosphate (1,5H2-FMN) to genera...

journal_title：Photochemistry and photobiology

authors： Wada N,Sugimoto T,Watanabe H,Tu SC

更新日期：1999-07-01 00:00:00

abstract：:The bimolecular rate constants (k) of quenching of molecular singlet oxygen 1O2 (1 delta g) by organo-selenium compounds exhibiting glutathione peroxidase activity and by sulfur analogs have been determined by time resolved phosphorescence detection of 1O2 in CD3OD and C6D6, with no solvent effect. The rate constants ...

journal_title：Photochemistry and photobiology

authors： Scurlock R,Rougée M,Bensasson RV,Evers M,Dereu N

更新日期：1991-11-01 00:00:00

abstract：:Fabrea salina is a marine ciliate that shows photomotile responses such as positive phototaxis and a step-down photophobic reaction. We found that preilluminated F. salina cells show a phototactic response significantly greater than that of dark-adapted cells when exposed to the same phototactic light stimulus. In par...

journal_title：Photochemistry and photobiology

authors： Marangoni R,Colombetti G

更新日期：2003-02-01 00:00:00

abstract：:The process of photoinduced hydroxylaminolysis has been re-examined in different bacteriorhodopsin (BR)-based media using O-substituted hydroxylamines, in particular, O-(4-nitrobenzyl) hydroxylamine hydrochloride (NBHA), O-(2,3,4,5,6-pentafluorobenzyl) hydroxylamine hydrochloride (FBHA) and O-(t-butyl) hydroxylamine h...

journal_title：Photochemistry and photobiology

authors： Dyukova TV,Druzhko AB

更新日期：2010-11-01 00:00:00

abstract：:Detergent solubilized bacteriorhodopsin (BR) proteins which contain alterations made by site-directed mutagenesis (Asp-96----Asn, D96N; Asp-85----Asn, D85N; and Arg-82----Gln, R82Q) have been studied with resonance Raman spectroscopy. Raman spectra of the light-adapted (BRLA) and M species in D96N are identical to tho...

journal_title：Photochemistry and photobiology

authors： Lin SW,Fodor SP,Miercke LJ,Shand RF,Betlach MC,Stroud RM,Mathies RA

更新日期：1991-03-01 00:00:00

abstract：:Photochemo and photodynamic therapies are minimally invasive approaches for the treatment of cancers and powerful weapons for competing bacterial resistance to antibiotics. Synthetic and naturally occurring quinazolinones are considered privileged anticancer and antibacterial agents, with several of them to have emerg...

journal_title：Photochemistry and photobiology

authors： Panagopoulos A,Balalas T,Mitrakas A,Vrazas V,Katsani KR,Koumbis AE,Koukourakis MI,Litinas KE,Fylaktakidou KC

更新日期：2021-01-01 00:00:00

abstract：:Liposomes were prepared from mixtures of dipalmitoyl-L-alpha-phosphatidylcholine and up to 40% mol:mol of N-stearoyl-L-histidine (NSH) in the presence of the hydrophobic sensitizer DHE. In the dark such liposomes are stable and retain entrapped salts. On photolysis with visible light, liposomes leak trapped ions at NS...

journal_title：Photochemistry and photobiology

authors： Chowdhary RK,Green CA,Morgan CG

更新日期：1993-09-01 00:00:00

abstract：:A concept has been presented whereby X-ray irradiation can be used to induce visible luminescence of chromophores such as porphyrins. The essential aspects of the idea have been demonstrated in a supramolecular assembly consisting of a water-dispersed polystyrene latex with an embedded scintillating compound, 2,5-diph...

journal_title：Photochemistry and photobiology

authors： Kokotov S,Lewis A,Neumann R,Amrusi S

更新日期：1994-03-01 00:00:00