Bringing It All Together: Coupling Excision Repair to the DNA Damage Checkpoint.

abstract：:The inefficient endosomal escape of drugs or macromolecules is a major obstacle to achieving successful delivery to therapeutic targets. An efficient approach to circumvent this barrier is photochemical internalization (PCI), which uses light and photosensitizers for endosomal escape of the delivered macromolecules. T...

journal_title：Photochemistry and photobiology

authors： Soe TH,Nanjo T,Watanabe K,Ohtsuki T

更新日期：2019-11-01 00:00:00

abstract：:Antifungal activity is positively correlated to furanocoumarin content in extracts of the traditional phytomedicine northern prickly ash (Zanthoxylum americanum Mill. [Rutaceae]). The specificity of these furanocoumarins in inhibiting replication of DNA was investigated with reference to significant base composition d...

journal_title：Photochemistry and photobiology

authors： Smith ML,Gregory P,Bafi-Yeboa NF,Arnason JT

更新日期：2004-06-01 00:00:00

abstract：:Melatonin (N-acetyl-5-methoxytryptamine) is a naturally occurring hormone with a structural resemblance to tryptophan. Its fluorescence is solvent dependent and strongly quenched in the presence of oxygen. Fluorescence quenching in aqueous and organic solutions have been studied in the presence of different quenchers....

journal_title：Photochemistry and photobiology

authors： Rath MC,Mahal HS,Mukherjee T

更新日期：1999-03-01 00:00:00

abstract：:Aspects of different calibration procedures for erythemally weighing broadband radiometers are presented in this study. These instruments are common in projects dealing with ultraviolet radiation effects on humans. Many erythemally weighing broadband radiometers are still operated using a single calibration factor (cf...

journal_title：Photochemistry and photobiology

authors： Oppenrieder A,Hoeppe P,Koepke P,Reuder J,Schween J,Schreder J

更新日期：2003-12-01 00:00:00

abstract：:Three Donor-π-Acceptor-π-Donor type styryl dyes (5a-c) with different secondary donors are synthesized and characterized to study their nonlinear and linear optical properties. The structure-property relationships of the dyes are described in the light of systematic photophysical and theoretical investigations. The ph...

journal_title：Photochemistry and photobiology

authors： Raikwar MM,Mathew E,Varghese M,Joe IH,Nethi SN

更新日期：2019-07-01 00:00:00

abstract：:The individual tryptophanyl contributions to the near-ultraviolet dichroic activity of apomyoglobin in its native conformation have been resolved. This was accomplished by comparing the spectra of two classes of apomyoglobin with different aromatic residue contents and observing the effect of a specific modification o...

journal_title：Photochemistry and photobiology

authors： Sirangelo I,Irace G,Bismuto E

更新日期：1994-06-01 00:00:00

abstract：:During the photoreaction cycle of photoactive yellow protein (PYP), a physiologically active intermediate (PYP(M)) is formed as a consequence of global protein conformational change. Previous studies have demonstrated that the photocycle of PYP is regulated by the N-terminal loop region, which is located across the ce...

journal_title：Photochemistry and photobiology

authors： Harigai M,Kataoka M,Imamoto Y

更新日期：2008-07-01 00:00:00

abstract：:The photodegradation of the S(+)- and R(-)-ketoprofen (KP) enantiomers in the bovine serum albumin matrix was studied by steady-state photolysis with the use of lambda(irr) > 320 nm and transient absorption spectroscopy with lambda(exc) = 355 nm, at 1/1 and 2/1 KP/BSA molar ratios. R(-)-KP was found to be more labile ...

journal_title：Photochemistry and photobiology

authors： Monti S,Manet I,Manoli F,Morrone R,Nicolosi G,Sortino S

更新日期：2006-01-01 00:00:00

abstract：:Ring-fused retinal analogs were designed to examine the hula-twist mode of the photoisomerization of the 9-cis retinylidene chromophore. Two 9-cis retinal analogs, the C11-C13 five-membered ring-fused and the C12-C14 five-membered ring-fused retinal derivatives, formed the pigments with opsin. The C11-C13 ring-fused a...

journal_title：Photochemistry and photobiology

authors： Hirano T,Lim IT,Kim DM,Zheng XG,Yoshihara K,Oyama Y,Imai H,Shichida Y,Ishiguro M

更新日期：2002-12-01 00:00:00

abstract：:The photoprocesses of berberine, palmatine, coralyne, sanguinarine, flavopereirine and ellipticine were studied in several solvents. The quantum yields Φ(Δ) of singlet molecular oxygen formation of berberine, palmatine and sanguinarine are moderate in dichloromethane (0.2-0.6) and much smaller in acetonitrile or trifl...

journal_title：Photochemistry and photobiology

authors： Görner H,Miskolczy Z,Megyesi M,Biczók L

更新日期：2011-03-01 00:00:00

abstract：:The classic method of photometric curves for photosensitivity determination has been extended to the case of photoreversible reactions and applied to the octopus rhodopsin --> acid metarhodopsin photoreaction. In such cases, measurements at one irradiation wavelength yield the sum of the photosensitivities of the forw...

journal_title：Photochemistry and photobiology

authors： Dixon SF,Cooper A

更新日期：1987-07-01 00:00:00

abstract：:We investigated the hypothesis that the strength of the activation of the intra-S DNA damage checkpoint varies within the S phase. Synchronized diploid human fibroblasts were exposed to either 0 or 2.5 J m(-2) UVC in early, mid- and late-S phase. The endpoints measured were the following: (1) radio-resistant DNA synth...

journal_title：Photochemistry and photobiology

authors： Chastain PD 2nd,Brylawski BP,Zhou YC,Rao S,Chu H,Ibrahim JG,Kaufmann WK,Cordeiro-Stone M

更新日期：2015-01-01 00:00:00

abstract：:Ultraviolet photolesions endow DNA with distinct structural and dynamic properties. Biophysical studies of photoproduct-containing DNA have shown that these lesions affect the mutagenic properties of DNA and damage recognition by DNA repair systems. Recently obtained high-resolution cocrystal structures of damaged DNA...

journal_title：Photochemistry and photobiology

authors： Park CJ,Lee JH,Choi BS

更新日期：2007-01-01 00:00:00

abstract：:A model of UV-induced DNA damage in oceanic bacterioplankton was developed and tested against previously published and novel measurements of cyclobutane pyrimidine dimers (CPD) in surface layers of the ocean. The model describes the effects of solar irradiance, wind-forced mixing of bacterioplankton and optical proper...

journal_title：Photochemistry and photobiology

authors： Huot Y,Jeffrey WH,Davis RF,Cullen JJ

更新日期：2000-07-01 00:00:00

abstract：:High intensity two-photon picosecond excitation at 266 nm (effective energy 9.2 eV) has been shown to cause efficient photolysis of thymine in aqueous solution. Experimental results for the quantum yield of solvated electrons, phi (eaq-), and the net consumption of thymine, phi(-Thy) have been interpreted (Oraevsky an...

journal_title：Photochemistry and photobiology

authors： Daniels M

更新日期：1991-07-01 00:00:00

abstract：:Aqueous solutions of KI were examined for use as chemical actinometers to measure 254 nm (germicidal) radiation. Irradiation results in electron ejection from iodide such that aqueous electrons and iodine atoms are formed. In the presence of N2O, an electron scavenger, recombination of these two reactive species is el...

journal_title：Photochemistry and photobiology

authors： Rahn RO

更新日期：1993-12-01 00:00:00

abstract：:We report here preliminary pilot study data of the effect of sunless tanning spray with 9% [Correction added after online publication (August 24th, 2009): The concentration of Dihydroxyacetone used in the study was 9% and not 3% as previously stated] dihydroxyacetone (DHA) on 25-hydroxyvitamin D [25(OH)D] serum levels...

journal_title：Photochemistry and photobiology

authors： Armas LA,Fusaro RM,Sayre RM,Huerter CJ,Heaney RP

更新日期：2009-09-01 00:00:00

abstract：:The progressive loss of visual faculties with advancing age is attributed, sometimes, mainly to allegedly inevitable optical deterioration, such as clouding of the media, or again to neurosenescence, as typified by cell-death. The relevant factors are assessed, and it is not thought likely that changes in normal ocula...

journal_title：Photochemistry and photobiology

authors： Weale RA

更新日期：1989-09-01 00:00:00

abstract：:Analysis of phosphorescence lifetimes using the Stern-Volmer equation is a reliable means of determining quencher concentration for a uniform sample. Methods of analysis for heterogeneous systems are based on the assumption that the excitation is produced by a momentary flash. This condition is an idealization because...

journal_title：Photochemistry and photobiology

authors： Golub AS,Popel AS,Zheng L,Pittman RN

更新日期：1999-06-01 00:00:00

abstract：:Phototropin is a blue light-activated photoreceptor that plays a dominant role in the phototropism of plants. The protein contains two subunits that bind flavin mononucleotide (FMN), which are responsible for the initial steps of the light-induced reaction. It has been proposed that the photoexcited flavin molecule ad...

journal_title：Photochemistry and photobiology

authors： Neiss C,Saalfrank P

更新日期：2003-01-01 00:00:00

abstract：:Ultraviolet radiation (UVR) is hazardous to patients with photosensitive skin disorders, such as lupus erythematosus, xeroderma pigmentosum and skin cancer. As such, these patients are advised to minimize their exposure to UVR. Classically, this is accomplished through careful avoidance of sun exposure and artificial ...

journal_title：Photochemistry and photobiology

authors： Klein RS,Werth VP,Dowdy JC,Sayre RM

更新日期：2009-07-01 00:00:00

abstract：:In the present study, hypericin analogs with an increased hydrophilic character were synthesized. As chemical modifications alter the lipophilicity/hydrophilicity balance together with the photophysical/chemical background of the molecule the influence of these structural changes on the cellular uptake, retention and ...

journal_title：Photochemistry and photobiology

authors： Delaey EM,Obermuëller R,Zupkó I,De Vos D,Falk H,de Witte PA

更新日期：2001-08-01 00:00:00

abstract：:Spatio-temporal patterns in sun exposure underlie variations in skin cancer incidence and vitamin D deficiency, indicate effectiveness of sun protection programs and provide insights into future health risks. From 558 adults across four regions of Australia (Brisbane (27°S), Newcastle (33°S), Geelong and the Western D...

journal_title：Photochemistry and photobiology

authors： Lucas RM,Valery P,van der Mei I,Dwyer T,Pender MP,Taylor B,Ponsonby AL,Ausimmune Investigator Group.

更新日期：2013-05-01 00:00:00

abstract：:The Escherichia coli protein YcgF contains a photosensory flavin adenine dinucleotide (FAD)-binding BLUF domain covalently linked to an EAL domain, which is predicted to have cyclic-di-guanosine monophosphate (GMP) phosphodiesterase activity. We have cloned, overexpressed and purified this protein, which we refer to a...

journal_title：Photochemistry and photobiology

authors： Rajagopal S,Key JM,Purcell EB,Boerema DJ,Moffat K

更新日期：2004-11-01 00:00:00

abstract：:The broad-band normal incidence UVB beam radiation has been measured at Neve Zohar, Dead Sea basin, using a prototype tracking instrument composed of a Model 501A UV-Biometer mounted on an Eppley Solar Tracker Model St-1. The diffuse and beam fraction of the solar global UVB radiation have been determined using the co...

journal_title：Photochemistry and photobiology

authors： Kudish AI,Harari M,Evseev EG

更新日期：2011-01-01 00:00:00

abstract：:We report here the design and synthesis of porphyrin-metallocene dyads consisting of a metallocene [either ferrocene or mixed sandwich η(5)-[C5H4(COOH)]Co(η(4)-C4Ph4) connected via an ester linkage at meso phenyl position of either free-base or zinc porphyrin. All these dyad systems were characterized by various spect...

journal_title：Photochemistry and photobiology

authors： Gokulnath S,Achary BS,Kumar CK,Trivedi R,Sridhar B,Giribabu L

更新日期：2015-01-01 00:00:00

abstract：:Channelrhodopsins act as photoreceptors for control of motility behavior in flagellates and are widely used as genetically targeted tools to optically manipulate the membrane potential of specific cell populations ("optogenetics"). The first two channelrhodopsins were obtained from the model organism Chlamydomonas rei...

journal_title：Photochemistry and photobiology

authors： Hou SY,Govorunova EG,Ntefidou M,Lane CE,Spudich EN,Sineshchekov OA,Spudich JL

更新日期：2012-01-01 00:00:00

abstract：:The protein environments surrounding the retinal tune electronic absorption maximum from 350 to 630 nm. Hybrid quantum mechanical/molecular mechanical (QM/MM) methods can be used in calculating excitation energies of retinal in its native protein environments and in studying the molecular basis of spectral tuning. We ...

journal_title：Photochemistry and photobiology

authors： Altun A,Yokoyama S,Morokuma K

更新日期：2008-07-01 00:00:00

abstract：:We have compared the distributions of two stable UV photoproducts in nucleosome core DNA at the single-nucleotide level using a T4 polymerase-exonuclease mapping procedure. The distribution of pyrimidine-pyrimidone (6-4) dimers was uncovered by reversing the major UV photo-product, cis-syn cyclobutane pyrimidine dimer...

journal_title：Photochemistry and photobiology

authors： Gale JM,Smerdon MJ

更新日期：1990-04-01 00:00:00

abstract：:Unidirectional blue light directs the rhizoid-thallus axis in the apolar zygote of the brown alga, Silvetia compressa. This effect is mediated by an increase in the intracellular concentration of guanosine 3', 5'-cyclic monophosphate. In this study we show the identification of a rhodopsin-like protein, by means of an...

journal_title：Photochemistry and photobiology

authors： Gualtieri P,Robinson KR

更新日期：2002-01-01 00:00:00