Photophysics of melatonin in different environments.

Abstract:

:Melatonin (N-acetyl-5-methoxytryptamine) is a naturally occurring hormone with a structural resemblance to tryptophan. Its fluorescence is solvent dependent and strongly quenched in the presence of oxygen. Fluorescence quenching in aqueous and organic solutions have been studied in the presence of different quenchers. A 1: 1 inclusion complex formation between melatonin and different cyclodextrins in aqueous solution has been observed. The effects of microheterogeneous media provided by cyclodextrins, micelles and reverse micelles on the fluorescence characteristics of melatonin have been investigated. The water-soluble inorganic quenchers like KBr and KI were unable to quench the fluorescence of melatonin dissolved in a microemulsion consisting of surfactant + cyclohexane + 1-propanol + water, whereas the organic quenchers like CCl4 and CHCl3 were able to quench the fluorescence with a rate constant (on the order of 10(8) dm3 mol-1 s-1) quite similar to that in neat organic solvents.

journal_name

Photochem Photobiol

authors

Rath MC,Mahal HS,Mukherjee T

doi

10.1562/0031-8655(1999)069<0294:pomide>2.3.co;2

subject

Has Abstract

pub_date

1999-03-01 00:00:00

pages

294-300

issue

3

eissn

0031-8655

issn

1751-1097

journal_volume

69

pub_type

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