In vivo spectrophotometric evaluation of neoplastic and non-neoplastic skin pigmented lesions--I. Reflectance measurements.

Abstract:

:Reflectance spectrophotometry from 400 to 800 nm on different cutaneous pigmented lesions, including primary and metastatic malignant melanoma, pigmented nevi, lentigo and seborrhoeic keratosis, has been performed by using an external integrating sphere coupled to a spectrophotometer. Measurements show that reflectance spectra of the different lesions manifest dissimilar patterns, particularly in the near IR region. Comparison of reflectance of nevi with that of malignant melanomas results in a highly significant difference (P less than 10(-6)) between the two samples. Though interpretation of the spectra remains difficult as a result of the complexity of the optical processes of scattering and absorption, our results suggest that a detailed analysis of the reflectance spectrum may give clinically useful information, and could be utilized as an aid in clinical diagnosis of cutaneous pigmented lesions, especially where malignant melanoma is concerned.

journal_name

Photochem Photobiol

authors

Marchesini R,Brambilla M,Clemente C,Maniezzo M,Sichirollo AE,Testori A,Venturoli DR,Cascinelli N

doi

10.1111/j.1751-1097.1991.tb08470.x

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

77-84

issue

1

eissn

0031-8655

issn

1751-1097

journal_volume

53

pub_type

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