Safety and Clinical Impact of a Single Red Light Irradiation on Breast Tumor-Bearing Mice.

abstract：:Several studies in the literature indicate that histones (lysine rich proteins found associated with DNA in eukaryotic chromatin), as well as poly-L-lysine, can be photocross-linked by ultraviolet (UV) light to DNA in which 5-bromo-2'-deoxyuridine has been substituted for thymidine. To gain some insight into the possi...

journal_title：Photochemistry and photobiology

authors： Shetlar MD,Rose RB,Hom K,Shaw AA

更新日期：1991-05-01 00:00:00

abstract：:The maximum erythemal dose rate (EDRmax ) at the Earth's surface tends to occur at local noon. However, clouds can make the timing of EDRmax significantly away from local noon. In fact, EDRmax and its time of occurrence depend mainly on the solar zenith angle at noon (SZAn ), site's altitude, the total ozone column (T...

journal_title：Photochemistry and photobiology

authors： Silva AA,Yamamoto ALC,Corrêa MP

更新日期：2019-05-01 00:00:00

abstract：:Angelica archangelia (AA), a traditional herb, has attracted attention as an agent with potential for use in the prevention of chronic skin diseases. This study examined the photoprotective effects of AA on the inhibition of matrix metalloproteinases (MMPs) and collagen degradation in UVB-irradiated normal human derma...

journal_title：Photochemistry and photobiology

authors： Sun Z,Hwang E,Park SY,Zhang M,Gao W,Lin P,Yi TH

更新日期：2016-07-01 00:00:00

abstract：:During the photoreaction cycle of photoactive yellow protein (PYP), a physiologically active intermediate (PYP(M)) is formed as a consequence of global protein conformational change. Previous studies have demonstrated that the photocycle of PYP is regulated by the N-terminal loop region, which is located across the ce...

journal_title：Photochemistry and photobiology

authors： Harigai M,Kataoka M,Imamoto Y

更新日期：2008-07-01 00:00:00

abstract：:The XPA gene-deficient mouse, an animal model of xeroderma pigmentosum (XP), develops enhanced photobiologic reactions including acute inflammation, immunosuppression and skin carcinogenesis, because of the defect in the excision repair of ultraviolet-induced DNA lesions. The results strongly suggest that nuclear DNA ...

journal_title：Photochemistry and photobiology

authors： Horio T,Miyauchi-Hashimoto H,Kuwamoto K,Yamazaki F,Okamoto H

更新日期：2007-01-01 00:00:00

abstract：:Photolysis of 6-chloro-1,3-dimethyluracil and mesitylene in the presence of trifluoroacetic acid (TFA) at low temperature gave 1,3,5,7,9- and 1,3,6,8,10-pentamethylcyclooctapyrimidine-2,4-diones (1b, 1c). Sequential photoreaction of the former (1b) resulted in the formation of 9,11-diazapentacyclo[6.4.0.0(1,3).0(2,5)....

journal_title：Photochemistry and photobiology

authors： Ohkura K,Nishijima K,Seki K

更新日期：2001-09-01 00:00:00

abstract：:Molecular beacons (MB) are becoming more common as sequence-selective detectors of nucleic acids. Although they can easily detect single-base mismatches, they have never been used to directly detect DNA or RNA damage. To measure the degree of ultraviolet (UV) light damage in oligonucleotides, we report a novel MB appr...

journal_title：Photochemistry and photobiology

authors： Yarasi S,McConachie C,Loppnow GR

更新日期：2005-03-01 00:00:00

abstract：:Latia neritoides is a small limpet-like snail that produces a bright green bioluminescence (BL) via a unique light-emitting system. The process, mechanism, and even light emitter of its light emission remain unknown, although this BL has been known for decades. Unlike the other BL systems, neither the luciferin (Luc) ...

journal_title：Photochemistry and photobiology

authors： Yu M,Ohmiya Y,Naumov P,Liu YJ

更新日期：2018-05-01 00:00:00

abstract：:We compared mutagenesis and sister chromatid exchange (SCE) induction by 193 nm and 308 nm pulsed excimer laser radiation with 254 nm low intensity continuous wave UV light in Chinese hamster ovary (CHO) cells in culture. The 254 nm radiation was most mutagenic of the radiations, in accordance with expectation, and al...

journal_title：Photochemistry and photobiology

authors： Rasmussen RE,Hammer-Wilson M,Berns MW

更新日期：1989-04-01 00:00:00

abstract：:Photoreduction of cytochrome c (Cyt c) has been reinvestigated using femtosecond-to-nanosecond transient absorption and stationary spectroscopy. Femtosecond spectra of oxidized Cyt c, recorded in the probe range 270-1000 nm, demonstrate similar evolution upon 266 or 403 nm excitation: an ultrafast 0.3 ps internal conv...

journal_title：Photochemistry and photobiology

authors： Löwenich D,Kleinermanns K,Karunakaran V,Kovalenko SA

更新日期：2008-01-01 00:00:00

abstract：:We describe here the development of monoclonal antibodies to the hapten tryptophan-riboflavin, generated by irradiation of a solution of bovine serum albumin in the presence of riboflavin. The specificity of the three obtained monoclonal antibodies, named 1E6, 5H5, 5A8 all belonging to the IgG1 isotype, was assessed b...

journal_title：Photochemistry and photobiology

authors： Diaz M,Becker MI,De Ioannes AE,Silva E

更新日期：1996-06-01 00:00:00

abstract：:New thio- and seleno-analogs of psoralen were synthesized and analyzed for their photoreactivity toward DNA. Using oligonucleotides of defined sequence, we first showed that these derivatives predominantly generated interstrand crosslinks at 5'-TpA sites. We also observed a surprisingly high reactivity of 7H-thiopyran...

journal_title：Photochemistry and photobiology

authors： Collet M,Sage E,Piette J

更新日期：1997-08-01 00:00:00

abstract：:Demetalation kinetics of bacteriochlorophylls (BChls) c, d and e from green sulfur photosynthetic bacteria were studied under weakly acidic conditions. Demetalation rate constants of BChl e possessing a formyl group at the 7-position were significantly smaller than those of BChls c and d, which had a methyl group at t...

journal_title：Photochemistry and photobiology

authors： Hirai Y,Tamiaki H,Kashimura S,Saga Y

更新日期：2009-09-01 00:00:00

abstract：:The phototoxic effects of demethylchlortetracycline (DMCT) with UVA radiation on isolated rat liver mitochondria were studied. DMCT at concentration of 21.5 microM with 5.53 x 10(-2) J cm-3 of UVA was found to be a potent uncoupler of oxidative phosphorylation. DMCT alone also uncoupled mitochondria but at higher conc...

journal_title：Photochemistry and photobiology

authors： Takagi S,Mizuno N,Adachi K,Wakabayashi T

更新日期：1990-02-01 00:00:00

abstract：:In eukaryotic cells helix-distorting DNA lesions like cyclobutane pyrimidine dimers (CPDs) and 6-4 pyrimidine-pyrimidone photoproducts (6-4 PPs) are efficiently removed by nucleotide excision repair (NER). NER is a multistep process where in the end, subsequent to replication over the gap, the remaining nick is sealed...

journal_title：Photochemistry and photobiology

authors： Paul-Konietzko K,Thomale J,Arakawa H,Iliakis G

更新日期：2015-09-01 00:00:00

abstract：:The phototransduction cascade is perhaps the best understood model system for G protein-coupled receptor (GPCR) signaling. Phototransduction links the absorption of a single photon of light to a decrease in cytosolic cGMP. Depletion of the cGMP pool induces closure of cGMP-gated cation channels resulting in the hyperp...

journal_title：Photochemistry and photobiology

authors： Lodowski DT,Angel TE,Palczewski K

更新日期：2009-03-01 00:00:00

abstract：:Exposure to ultraviolet radiation results in increased levels of intradermal cis-urocanic acid (cUCA) and alters cutaneous immunity by interfering with processing and presentation of antigen by Langerhans cells. Reports on effects of systemic immunotoxicity with 30 day cUCA exposure in laboratory rodents include thymi...

journal_title：Photochemistry and photobiology

authors： Prater MR,Gogal RM Jr,De Fabo EC,Longstreth J,Holladay SD

更新日期：2003-04-01 00:00:00

abstract：:Synovial sarcoma (SS) is one of common malignant soft-tissue tumors and is encountered most commonly in children and young adults. It frequently involves or invades major neurovascular structures and bones, and its local recurrence rate after simple resection has been reported to be as high as up to 80%. Because major...

journal_title：Photochemistry and photobiology

authors： Kusuzaki K,Murata H,Matsubara T,Miyazaki S,Shintani K,Seto M,Matsumine A,Hosoi H,Sugimoto T,Uchida A

更新日期：2005-05-01 00:00:00

abstract：:The marine annelid Chaetopterus variopedatus produces bioluminescence by an unknown and potentially novel mechanism. We have advanced the study of this fascinating phenomenon, which has not been investigated for nearly 60 years after initial studies were first reported for this species. Here, we show that the luminous...

journal_title：Photochemistry and photobiology

authors： Branchini BR,Behney CE,Southworth TL,Rawat R,Deheyn DD

更新日期：2014-01-01 00:00:00

abstract：:The UV radiation environment on planetary surfaces and within atmospheres is of importance in a wide range of scientific disciplines. Solar UV radiation is a driving force of chemical and organic evolution and serves also as a constraint in biological evolution. In this work we modeled the transmission of present and ...

journal_title：Photochemistry and photobiology

authors： Rontó G,Bérces A,Lammer H,Cockell CS,Molina-Cuberos GJ,Patel MR,Selsis F

更新日期：2003-01-01 00:00:00

abstract：:Previous studies have shown that natural killer (NK) cell activity was suppressed in volunteer subjects exposed to ultraviolet radiation (UVR) from solarium lamps. The present studies were carried out to determine the spectrum of UVR responsible for suppression of NK activity and to develop in vitro methods to analyze...

journal_title：Photochemistry and photobiology

authors： Hersey P,Magrath H,Wilkinson F

更新日期：1993-02-01 00:00:00

abstract：:Solar ultraviolet B (UVB) radiation has been shown to induce inflammation, DNA damage, p53 mutations and alterations in signaling pathways eventually leading to skin cancer. In this study, we investigated whether fisetin reduces inflammatory responses and modulates PI3K/AKT/NFκB cell survival signaling pathways in UVB...

journal_title：Photochemistry and photobiology

authors： Pal HC,Athar M,Elmets CA,Afaq F

更新日期：2015-01-01 00:00:00

abstract：:Previous studies have reported that 450 nm blue light emitting diode (BLED) induces apoptosis through a mitochondria-mediated pathway in cancer cells and reduces the early stage tumor growth. This study was performed to determine the effects of BLED-irradiated cell metabolites on cell injury. Our results showed that c...

journal_title：Photochemistry and photobiology

authors： Oh PS,Kim EM,Kim M,Kim IS,Han YH,Lim S,Sohn MH,Ko MH,Jeong HJ

更新日期：2018-05-01 00:00:00

abstract：:The photophysical characteristics of two second-generation PDT photosensitizers, tin ethyl etiopurpurin I (SnET2) and tin octaethylbenzochlorin (SnOEBC), have been measured in homogeneous solution and when bound to bovine serum albumin (BSA). The ground state and triplet state absorption spectra have been characterize...

journal_title：Photochemistry and photobiology

authors： Pogue BW,Redmond RW,Trivedi N,Hasan T

更新日期：1998-12-01 00:00:00

abstract：:As our understanding of the role of UV in causing skin cancer continues to expand, researchers and clinicians must continue to remain up to date on the various means by which UV exposure can be quantified. The purpose of this article was to review the current methods used to measure lifetime exposure to UV and to summ...

journal_title：Photochemistry and photobiology

authors： Worswick SD,Cockburn M,Peng D

更新日期：2008-11-01 00:00:00

abstract：:We investigated the effect of the cation-π interaction on the susceptibility of a tryptophan model system toward interaction with singlet oxygen, that is, type II photooxidation. The model system consists of two indole units linked to a lariat crown ether to measure the total rate of removal of singlet oxygen by the i...

journal_title：Photochemistry and photobiology

authors： Arevalo GE,Cagan DA,Monsour CG,Garcia AC,McCurdy A,Selke M

更新日期：2020-11-01 00:00:00

abstract：:The retinal pigment epithelium (RPE) is a highly metabolic layer of postmitotic cells lining Bruch's membrane in the retina. While these cells contain endogenous photosensitizers that mediate blue light-induced damage, it has also been shown that blue light exposure damages mitochondrial DNA in RPE cells resulting in ...

journal_title：Photochemistry and photobiology

authors： Yacout SM,Gaillard ER

更新日期：2017-03-01 00:00:00

abstract：:The bimolecular rate constants (k) of quenching of molecular singlet oxygen 1O2 (1 delta g) by organo-selenium compounds exhibiting glutathione peroxidase activity and by sulfur analogs have been determined by time resolved phosphorescence detection of 1O2 in CD3OD and C6D6, with no solvent effect. The rate constants ...

journal_title：Photochemistry and photobiology

authors： Scurlock R,Rougée M,Bensasson RV,Evers M,Dereu N

更新日期：1991-11-01 00:00:00

abstract：:Copper(II), in the presence of UV-B radiation (280-315 nm), can generate single-strand breaks in the sugar-phosphate backbone of pBR322 plasmid DNA. A low level of single-strand backbone breaks occurs in the presence of Cu(II) alone, but UV-B irradiation increases the rate by the more than 100-fold. Concomitant with t...

journal_title：Photochemistry and photobiology

authors： Lloyd RE,Larson RA,Adair TL,Tuveson RW

更新日期：1993-06-01 00:00:00

abstract：:2-Aminoacetophenone (AAP) was recognized as the key compound for the so-called untypical aging off-flavor (UTA) in Vitis vinifera wines. In this study, it was shown that AAP can be formed by photooxidation of free and protein-bound tryptophan (TRP) in combination with a subsequent storage in model wine. Solutions of T...

journal_title：Photochemistry and photobiology

authors： Horlacher N,Schwack W

更新日期：2014-11-01 00:00:00