Photobiological information obtained from XPA gene-deficient mice.

Abstract:

:The XPA gene-deficient mouse, an animal model of xeroderma pigmentosum (XP), develops enhanced photobiologic reactions including acute inflammation, immunosuppression and skin carcinogenesis, because of the defect in the excision repair of ultraviolet-induced DNA lesions. The results strongly suggest that nuclear DNA is an important chromophore to initiate acute and chronic skin damages. The model mouse is a useful experimental animal not only to investigate the mechanisms of photosensitivity in XP, but also to study physiological photobiology in humans, because photobiologic reactions are greatly intensified in this mouse.

journal_name

Photochem Photobiol

authors

Horio T,Miyauchi-Hashimoto H,Kuwamoto K,Yamazaki F,Okamoto H

doi

10.1562/2006-03-02-IR-829

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

218-24

issue

1

eissn

0031-8655

issn

1751-1097

pii

2006-03-02-IR-829

journal_volume

83

pub_type

杂志文章,评审
  • In vitro Studies of Antitumor Effect, Toxicity/Cytotoxicity and Skin Permeation/Retention of a Green Fluorescence Pyrene-based Dye for PDT Application.

    abstract::Photosensitizers (PS) are compounds that can generate reactive oxygen species under irradiation of appropriate light and are widely used in photodynamic therapy (PDT). Currently, topical PDT is an effective treatment for several skin diseases, including bacterial infections, fungal mycoses and psoriasis. In addition, ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13335

    authors: de França BM,Ghasemishahrestani Z,de Souza GFM,da Silva RN,Queiroz DD,Pierre MBR,Pereira MD,Forero JSB,Corrêa RJ

    更新日期:2020-09-23 00:00:00

  • Determination by fluorimetric titration of the ionization constants of ciprofloxacin in solution and in the presence of liposomes.

    abstract::A fluorescence titration method was applied for the determination of pKa of ciprofloxacin (CPX) in solution. Values of 6.18 +/- 0.05 and 8.76 +/- 0.03 were obtained for pKa1 and pKa2, respectively. The method was used to determine the ionization constants in the presence of liposomes of dipalmitoylphosphatidylcholine ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2001)073<0014:dbftot>2.0.co;2

    authors: Vázquez JL,Berlanga M,Merino S,Domènech O,Viñas M,Montero MT,Hernández-Borrell J

    更新日期:2001-01-01 00:00:00

  • Evaluation of Photoprotective Potential and Percutaneous Penetration by Photoacoustic Spectroscopy of the Schinus terebinthifolius Raddi Extract.

    abstract::Schinus terebinthifolius is a plant rich in phenolic compounds, which have antioxidant properties and can provide new opportunities for treatment and prevention of diseases mediated by ultraviolet radiation like photoaging and skin cancer. The aim of this study was to evaluate the photoprotective potential and ex vivo...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12419

    authors: Bulla MK,Hernandes L,Baesso ML,Nogueira AC,Bento AC,Bortoluzzi BB,Serra LZ,Cortez DA

    更新日期:2015-05-01 00:00:00

  • Calculation of singlet oxygen dose using explicit and implicit dose metrics during benzoporphyrin derivative monoacid ring A (BPD-MA)-PDT in vitro and correlation with MLL cell survival.

    abstract::Photodynamic therapy (PDT) oxygen consumption, clonogenic cell survival, fluorescence photobleaching and photoproduct formation were investigated during benzoporphyrin derivative monoacid (BPD-MA)-PDT of MAT-LyLu cells in vitro. Cells were incubated with BPD-MA concentrations of 0.1, 0.5 or 2.5 μg mL(-1) for 2 h and t...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2011.00942.x

    authors: Weston MA,Patterson MS

    更新日期:2011-09-01 00:00:00

  • Analysis of compact fluorescent lights for use by patients with photosensitive conditions.

    abstract::Ultraviolet radiation (UVR) is hazardous to patients with photosensitive skin disorders, such as lupus erythematosus, xeroderma pigmentosum and skin cancer. As such, these patients are advised to minimize their exposure to UVR. Classically, this is accomplished through careful avoidance of sun exposure and artificial ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2009.00540.x

    authors: Klein RS,Werth VP,Dowdy JC,Sayre RM

    更新日期:2009-07-01 00:00:00

  • Mutation and sister chromatid exchange induction in Chinese hamster ovary (CHO) cells by pulsed excimer laser radiation at 193 nm and 308 nm and continuous UV radiation at 254 nm.

    abstract::We compared mutagenesis and sister chromatid exchange (SCE) induction by 193 nm and 308 nm pulsed excimer laser radiation with 254 nm low intensity continuous wave UV light in Chinese hamster ovary (CHO) cells in culture. The 254 nm radiation was most mutagenic of the radiations, in accordance with expectation, and al...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1989.tb09188.x

    authors: Rasmussen RE,Hammer-Wilson M,Berns MW

    更新日期:1989-04-01 00:00:00

  • The susceptibility of dermatophytes to photodynamic treatment with special focus on Trichophyton rubrum.

    abstract::Owing to the accessibility of skin to light, many applications of photodynamic treatment (PDT) have been developed within dermatology. The recent increase of dermatological antimicrobial PDT investigations is related to the growing problem of bacterial and fungal resistance to antibiotics. This review focuses on the s...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1751-1097.2010.00848.x

    authors: Smijs TG,Pavel S

    更新日期:2011-01-01 00:00:00

  • Early alterations of actin in cultured human keratinocytes and fibroblasts exposed to long-wavelength radiations. Possible involvement in the UVA-induced perturbations of endocytotic processes.

    abstract::Exposure of cultured MRC5 human fibroblasts or NCTC 2544 human keratinocytes to mild doses of ultraviolet A (UVA: 320-400 nm) radiations markedly decreased the actin reactivity with fluorescein-labeled phalloidin. This indicates a change in the degree of polymerization of actin and thus in the organization of actin fi...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1994.tb05000.x

    authors: Djavaheri-Mergny M,Pieraggi MT,Mazière C,Santus R,Lageron A,Salvayre R,Dubertret L,Mazière JC

    更新日期:1994-01-01 00:00:00

  • Constraints of opsin structure on the ligand-binding site: studies with ring-fused retinals.

    abstract::Ring-fused retinal analogs were designed to examine the hula-twist mode of the photoisomerization of the 9-cis retinylidene chromophore. Two 9-cis retinal analogs, the C11-C13 five-membered ring-fused and the C12-C14 five-membered ring-fused retinal derivatives, formed the pigments with opsin. The C11-C13 ring-fused a...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2002)076<0606:coosot>2.0.co;2

    authors: Hirano T,Lim IT,Kim DM,Zheng XG,Yoshihara K,Oyama Y,Imai H,Shichida Y,Ishiguro M

    更新日期:2002-12-01 00:00:00

  • The influence of ultraviolet-B radiation on growth, hydroxycinnamic acids and flavonoids of Deschampsia antarctica during Springtime ozone depletion in Antarctica.

    abstract::We examined the influence of solar ultraviolet-B radiation (UV-B; 280-320 nm) on the growth, biomass production and phenylpropanoid concentrations of Deschampsia antarctica during the springtime ozone depletion season at Palmer Station, along the Antarctic Peninsula. Treatments involved placing filters on frames over ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/2004-09-18-RA-321

    authors: Ruhland CT,Xiong FS,Clark WD,Day TA

    更新日期:2005-09-01 00:00:00

  • Flavin-based Blue-Light photosensors: a photobiophysics update.

    abstract::This review deals with the biophysical aspects of flavin-based photosensors, comprising cryptochromes, LOV (Light, Oxygen and Voltage) and BLUF (Blue Light sensing Using FAD) proteins. Special emphasis is given to structural issues, photocycle quantum yields and energetics, mechanism of the light-triggered reactions, ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1751-1097.2007.00196.x

    authors: Losi A

    更新日期:2007-11-01 00:00:00

  • A comparison of fluorescence methods used in the pharmacokinetic studies of Zn(II)phthalocyanine in mice.

    abstract::The pharmacokinetics of Zn phthalocyanine (ZnPc) encapsulated in dipalmitoyl-phosphatidylcholine (DPPC) liposomes, injected intravenously in Skh:HR-1 nude mice, was monitored by two in vitro techniques and one in vivo technique, all based on fluorescence spectroscopy. The in vitro methods involve either fluorescence m...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1991.tb08475.x

    authors: Biolo R,Jori G,Kennedy JC,Nadeau P,Pottier R,Reddi E,Weagle G

    更新日期:1991-01-01 00:00:00

  • Measurement of ultraviolet exposure in epidemiological studies of skin and skin cancers.

    abstract::As our understanding of the role of UV in causing skin cancer continues to expand, researchers and clinicians must continue to remain up to date on the various means by which UV exposure can be quantified. The purpose of this article was to review the current methods used to measure lifetime exposure to UV and to summ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2008.00367.x

    authors: Worswick SD,Cockburn M,Peng D

    更新日期:2008-11-01 00:00:00

  • From San Luis, A Few Words of Gratitude.

    abstract::The Photochemical Research Group from San Luis (Argentina) highlights the contributions of Dr. Norman Andino García to the development of the group as a way to show him our gratitude for all his support. ...

    journal_title:Photochemistry and photobiology

    pub_type: 社论

    doi:10.1111/php.12988

    authors: Ferrari G,Montaña MP

    更新日期:2018-11-01 00:00:00

  • A comparative pilot study of symptom improvement before and after phototherapy in Korean patients with perennial allergic rhinitis.

    abstract::Although allergic rhinitis is not life threatening, it significantly influences the quality of a patient's life. This study is intended to evaluate the safety and efficacy of phototherapy with low-level energy of a 650 nm laser irradiation system in perennial allergic rhinitis patients. This clinical trial was an open...

    journal_title:Photochemistry and photobiology

    pub_type: 临床试验,杂志文章

    doi:10.1111/php.12032

    authors: Lee HM,Park MS,Park IH,Lee SH,Lee SK,Kim KS,Choi H

    更新日期:2013-05-01 00:00:00

  • Novel Collimated Beam Setup to Study the Kinetics of VUV-Induced Reactions.

    abstract::Vacuum UV (VUV) process is an incipient advanced oxidation process, which can be used for water treatment. This process relies on the formation of hydroxyl radicals through the VUV-induced photolysis of water. In particular, the use of ozone-generating mercury vapor lamps, which emit 10% of the radiation at 185 nm and...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.12157

    authors: Duca C,Imoberdorf G,Mohseni M

    更新日期:2014-01-01 00:00:00

  • Fluorescence polarization studies of B-phycoerythrin oriented in polymer film.

    abstract::Polarized steady-state fluorescence and fluorescence excitation spectra as well as time-resolved fluorescence for B-phycoerythrin (B-PE) from red algae, Porphyridium cruentum, embedded in polyvinyl stretched films were measured. The lifetimes of polarized fluorescence were analyzed using exponential components and fra...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:

    authors: Frackowiak D,Ptak A,Gryczynski Z,Gryczynski I,Targowski P,Zelent B

    更新日期:2004-01-01 00:00:00

  • Oxygen dependence of hypericin-induced phototoxicity to EMT6 mouse mammary carcinoma cells.

    abstract::The photodynamic effect of hypericin on EMT6 mouse mammary carcinoma cells was investigated in vitro under aerobic and hypoxic conditions. Under aerobic conditions, hypericin-induced photocytotoxicity was dose dependent within a 1-50 microM range. Under hypoxic conditions, cells were resistant to hypericin-induced pho...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1992.tb08531.x

    authors: Thomas C,Pardini RS

    更新日期:1992-06-01 00:00:00

  • Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: a Double-blind, Randomized Placebo-controlled Clinical Study.

    abstract::Photoprotective formulations containing substances with antioxidant properties in combination have been used as a strategy for the improvement of photoaged skin conditions. However, there is a lack of studies evaluating the clinical efficacy of these substances in young women with signs of photoaging. Thus, the object...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13390

    authors: Fossa Shirata MM,Maia Campos PMBG

    更新日期:2021-02-02 00:00:00

  • Cancer Cell-targeted and Activatable Photoimmunotherapy Spares T Cells in a 3D Coculture Model.

    abstract::Photodynamic therapy (PDT) is an established therapeutic modality that uses nonionizing near-infrared light to activate photocytotoxicity of endogenous or exogenous photosensitizers (PSs). An ongoing avenue of cancer research involves leveraging PDT to stimulate antitumor immune responses; however, these effects appea...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13153

    authors: Kercher EM,Nath S,Rizvi I,Spring BQ

    更新日期:2020-03-01 00:00:00

  • Wavelength-dependent quantum yield for Z----E isomerization of bilirubin complexed with human serum albumin.

    abstract::The quantum yield, phi ZE, for configurational photoisomerization (4Z,15Z----4Z,15E) of bilirubin bound non-covalently to human serum albumin was determined (at 23 +/- 2 degrees C) by laser excitation and chromatographic analysis of products. Values obtained for photoexcitation at 465 nm were about one-half those prev...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1992.tb04226.x

    authors: Agati G,Fusi F,Pratesi R,McDonagh AF

    更新日期:1992-02-01 00:00:00

  • 6-Nitro-Quinazolin-4(3H)-one Exhibits Photodynamic Effects and Photodegrades Human Melanoma Cell Lines. A Study on the Photoreactivity of Simple Quinazolin-4(3H)-ones.

    abstract::Photochemo and photodynamic therapies are minimally invasive approaches for the treatment of cancers and powerful weapons for competing bacterial resistance to antibiotics. Synthetic and naturally occurring quinazolinones are considered privileged anticancer and antibacterial agents, with several of them to have emerg...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13376

    authors: Panagopoulos A,Balalas T,Mitrakas A,Vrazas V,Katsani KR,Koumbis AE,Koukourakis MI,Litinas KE,Fylaktakidou KC

    更新日期:2021-01-01 00:00:00

  • Phototaxis of Haloarcula marismortui revealed through a novel microbial motion analysis algorithm.

    abstract::Haloarcula marismortui has been described to be nonmotile prior to the recent identification of flagellar filaments, suggesting the motile nature of H. marismortui. Here we observed the locomotion of freshly cultured H. marismortui cells and tracked the swimming trajectories via ImageJ. Trajectories of H. marismortui ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.2010.00768.x

    authors: Lin YC,Fu HY,Yang CS

    更新日期:2010-09-01 00:00:00

  • Size and Substitution Effect on Antimicrobial Activity of Polythiophene Polyelectrolyte Derivatives Under Photolysis and Dark Conditions.

    abstract::Cationic polythiophenes have been shown to be potent antimicrobial compounds due to their ability to absorb visible light and sensitize the production of reactive oxygen species (ROS) as well as their ability to selectively associate with and damage negatively charged cell envelopes. This study demonstrates the abilit...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/php.13013

    authors: Brown DM,Yang J,Strach EW,Khalil MI,Whitten DG

    更新日期:2018-11-01 00:00:00

  • Comparison of nonmetal and metal hydrophilic photosensitizer, ATX-S10 (Na) and ATN-2, binding with human serum proteins using spectrophotometry.

    abstract::Intermolecular interactions of human serum proteins with a hydrophilic nonmetalloporphyrin, 13,17-bis(1-carboxypropionyl)carbomoylethyl-8-ethenyl-2-hydroxy-3-hydroxyiminoethylidene-2,7,12,18-tetramethylporphyrin sodium salt (ATX-S10 (Na)), or a hydrophilic gallium-metalloporphyrin, diethylenetriamine pentaacetic acid ...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/2004-03-17-RA-117

    authors: Yamaguchi M,Tanabe S,Nakajima S,Takemura T,Ogita K,Kuwayama H,Sakata I,Miyaki S,Suzuki K,Namiki H,Uzuka Y,Sarashina T

    更新日期:2004-09-01 00:00:00

  • Absorbance changes by aromatic amino acid side chains in early rhodopsin photointermediates.

    abstract::Absorbance changes were monitored from 250 to 650 nm during the first microsecond after photolysis of detergent suspensions of bovine rhodopsin at 20 degrees C. Global analysis of the resulting data produced difference spectra for bathorhodopsin, BSI and lumirhodopsin which give the change in absorbance of the aromati...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1111/j.1751-1097.1997.tb03218.x

    authors: Lewis JW,Jäger S,Kliger DS

    更新日期:1997-12-01 00:00:00

  • Casting Away the Shadows: Elucidating the Role of Light-mediated Posttranscriptional Control in Plants.

    abstract::Light signals trigger precise changes in gene expression networks that activate distinctive developmental programs in plants. The transcriptome is shaped at different stages, both by the regulation of gene expression and also by posttranscriptional mechanisms that alter the sequence or abundance of the transcripts gen...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审

    doi:10.1111/php.12762

    authors: Hernando CE,Garcia C,Mateos JL

    更新日期:2017-05-01 00:00:00

  • Induction of systemic neutrophil response in mice by photodynamic therapy of solid tumors.

    abstract::Photodynamic therapy (PDT) of solid tumors elicits a strong, acute inflammatory response characterized by a rapid and massive infiltration of activated neutrophils into the tumor. The present study investigated the impact of PDT on the systemic and local (treatment site) kinetics of neutrophil trafficking and activity...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2001)074<0712:iosnri>2.0.co;2

    authors: Cecic I,Parkins CS,Korbelik M

    更新日期:2001-11-01 00:00:00

  • Photosensitization reactions of fluoroquinolones and their biological consequences.

    abstract::This review focuses on damage photosensitized by the fluoroquinolone (FQ) antibacterial drugs. Different models are employed to study biosubstrate photodamage mediated by FQs (organisms, cells, isolated biomolecules and super molecules). Being that the effect of environment (polarity of the medium, ions, pH, binding w...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1751-1097.2011.00978.x

    authors: de Guidi G,Bracchitta G,Catalfo A

    更新日期:2011-11-01 00:00:00

  • Spectroscopic studies on self-aggregation of bacteriochlorophyll-e in nonpolar organic solvents: effects of stereoisomeric configuration at the 3(1)-position and alkyl substituents at the 8(1)-position.

    abstract::Self-aggregation of naturally occurring bacteriochlorophyll (BChl)-e in nonpolar organic solvents was investigated by visible absorption, fluorescence emission and circular dichroism spectra. Cultured brown-colored photosynthetic bacteria have several BChl-e as light-harvesting antenna pigments. Three major BChl-e hom...

    journal_title:Photochemistry and photobiology

    pub_type: 杂志文章

    doi:10.1562/0031-8655(2001)074<0072:ssosao>2.0.co;2

    authors: Saga Y,Matsuura K,Tamiaki H

    更新日期:2001-07-01 00:00:00