Early alterations of actin in cultured human keratinocytes and fibroblasts exposed to long-wavelength radiations. Possible involvement in the UVA-induced perturbations of endocytotic processes.

Abstract:

:Exposure of cultured MRC5 human fibroblasts or NCTC 2544 human keratinocytes to mild doses of ultraviolet A (UVA: 320-400 nm) radiations markedly decreased the actin reactivity with fluorescein-labeled phalloidin. This indicates a change in the degree of polymerization of actin and thus in the organization of actin filaments. Such a phenomenon might be involved in the previously reported UVA-induced inhibition of specific and nonspecific endocytotic processes.

journal_name

Photochem Photobiol

authors

Djavaheri-Mergny M,Pieraggi MT,Mazière C,Santus R,Lageron A,Salvayre R,Dubertret L,Mazière JC

doi

10.1111/j.1751-1097.1994.tb05000.x

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

48-52

issue

1

eissn

0031-8655

issn

1751-1097

journal_volume

59

pub_type

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