Flavin-based Blue-Light photosensors: a photobiophysics update.

Abstract:

:This review deals with the biophysical aspects of flavin-based photosensors, comprising cryptochromes, LOV (Light, Oxygen and Voltage) and BLUF (Blue Light sensing Using FAD) proteins. Special emphasis is given to structural issues, photocycle quantum yields and energetics, mechanism of the light-triggered reactions, early stages in signal transduction and oligomeric states of the light sensing protein modules. For BLUF and LOV domains important parallels are emerging, despite their different alpha/beta fold arrangement, whereas there is increasing evidence for a mechanicistic and functional splitting of the cryptochrome family.

journal_name

Photochem Photobiol

authors

Losi A

doi

10.1111/j.1751-1097.2007.00196.x

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

1283-300

issue

6

eissn

0031-8655

issn

1751-1097

pii

PHP196

journal_volume

83

pub_type

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