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Protease activity in the mouse dental follicle during tooth eruption.

Abstract：

:Eruption results in the movement of the tooth from an intraosseous to a functional position in the mouth. This physiological movement occurs through a path of least resistance and is mediated by the dental follicle. In this study the presence of a 80-kDa proteinase of the gelatinase family in the dental follicle of mandibular first molars obtained from CD-1 mouse neonates was investigated by zymography on sodium dodecyl sulphate-gelatin. The results showed a differential distribution of this proteinase in the coronal and apical parts of the follicle at postnatal days 9 and 11. The findings suggest that the onset of this differential enzymatic activity is concomitant with the initiation of tooth eruption.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Shroff B,Norris K,Pileggi R

doi

10.1016/0003-9969(94)00168-b

subject

Has Abstract

pub_date

1995-04-01 00:00:00

pages

331-5

issue

4

eissn

0003-9969

issn

1879-1506

pii

0003-9969(94)00168-B

journal_volume

40

pub_type

杂志文章

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