Endogenous retroviruses in the human genome--a point of view.

abstract：:The early region 1A (E1A) gene of highly oncogenic adenovirus type 12 (Ad12) was analyzed for transforming activity and protein binding using specific mutations. The Ad12 E1A proteins were found to bind p300 protein mainly within the CR1 region, although mutations that affect both p300 binding and transformation were ...

journal_title：Virus genes

authors： Sawada Y,Ishino M,Miura K,Ohtsuka E,Fujinaga K

更新日期：1997-01-01 00:00:00

abstract：:Glycoprotein K (gK) encoded by the UL53 gene is the ninth out of eleven HSV glycoproteins (gps). The precursor gK (pgK) is a transmembrane protein with four hydrophobic domains, which consists of 338 amino acids. The UL53 gene has two initiation codons: the upper overlaps with the UL52 ORF, while the lower is located ...

journal_title：Virus genes

authors： Rajcáni J,Kúdelová M

更新日期：1999-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a major global health issue. Although the search for HCV treatments has resulted in great achievements, the current treatment methods have limitations, and new methods and drugs for hepatitis C treatment are still required. The aim of the present study was to investigate the effect...

journal_title：Virus genes

authors： Dai R,Xiao X,Peng F,Li M,Gong G

更新日期：2016-02-01 00:00:00

abstract：:Adeno-associated virus (AAV) is a human parvovirus that in laboratory and animal models has the ability to suppress the oncogenic phenotype of a variety of viruses and cellular derived oncogenes. The inhibitory effects of AAV have been mapped to its rap gene (Rep78 protein). Furthermore, seroepidemiologic data indicat...

journal_title：Virus genes

authors： Han L,Parmley TH,Keith S,Kozlowski KJ,Smith LJ,Hermonat PL

更新日期：1996-01-01 00:00:00

abstract：:Avian reovirus infection causes considerable economic loss to the commercial poultry industry. Live-attenuated vaccine strain S1133 (v-S1133, derived from parent strain S1133) is considered the safest and most effective vaccine and is currently used worldwide. To identify the genes responsible for its attenuation, DNA...

journal_title：Virus genes

authors： Teng L,Xie Z,Xie L,Liu J,Pang Y,Deng X,Xie Z,Fan Q,Luo S,Feng J,Khan MI

更新日期：2014-04-01 00:00:00

abstract：:The UL24 gene of herpes simplex virus type 2 (HSV-2) is predicted to encode a 281 amino acid protein with a molecular mass of 30.5 kDa. In this study, the HSV-2 UL24 gene product has been identified by using a rabbit polyclonal antiserum produced against a recombinant protein containing the full-length UL24 gene produ...

journal_title：Virus genes

authors： Hong-Yan Z,Murata T,Goshima F,Takakuwa H,Koshizuka T,Yamauchi Y,Nishiyama Y

更新日期：2001-06-01 00:00:00

abstract：:The infection of humans with Boma disease virus (BDV) is still a matter of debate. In a recent publication, we described a BDV (RW98) isolated from the blood of a psychiatric patient. The RNA of this virus differed more than 5% from that of the widely used strain He/80, which was supposed to represent our laboratory v...

journal_title：Virus genes

authors： Planz O,Rziha HJ,Stitz L

更新日期：2003-01-01 00:00:00

abstract：:N20-RNA 3L, a large form of RNA 3 associated with Alfalfa mosaic virus (AMV) strain N20 comprises 2281 nt and has approximately 97% overall sequence similarity to the longest previously described RNA 3 of AMV strain YSMV (YSMV-RNA 3; 2188 nt). Compared with YSMV-RNA 3, N20-RNA 3L contains an additional 97 nt in the 5'...

journal_title：Virus genes

authors： Jayasena KW,Randles JW

更新日期：2004-12-01 00:00:00

abstract：:The Kansas/15626/84 (Ka) and Shipping Fever (SF) strains of bovine parainfluenza virus type 3 (BPIV3) replicate less efficiently than human PIV3 (HPIV3) in the upper and lower respiratory tract of rhesus monkeys, and BPIV3 Ka is also highly attenuated in humans and is in clinical trials as a candidate vaccine against ...

journal_title：Virus genes

authors： Bailly JE,McAuliffe JM,Skiadopoulos MH,Collins PL,Murphy BR

更新日期：2000-01-01 00:00:00

abstract：:Recent studies have shown that dual mutations in fp25K and p35 of Autographa californica nucleopolyhedrovirus (AcMNPV) result in a typical apoptotic infection on Trichoplusia ni cells, suggesting the involvement of FP25K on NPV-induced apoptosis. To examine the effect of fp25K deletion on Bombyx mori NPV (BmNPV)-induc...

journal_title：Virus genes

authors： Nakanishi T,Shimada T,Katsuma S

更新日期：2010-08-01 00:00:00

abstract：:The complete nucleotide sequence of rice tungro spherical virus (RTSV) strain Vt6, originally from Mindanao, the Philippines, with higher virulence to resistant rice cultivars, was determined and compared with the published sequence for the Philippine-type strain A (RTSV-A-Shen). It was reported that RTSV-A was not ab...

journal_title：Virus genes

authors： Isogai M,Cabauatan PQ,Masuta C,Uyeda I,Azzam O

更新日期：2000-01-01 00:00:00

abstract：:Deformed wing virus (DWV) is one of the most common viruses affecting honey bee specimens. Although the presence of DWV has been reported in many countries, there is no data of the current situation in Chile. In this report, we detected the presence of DWV in apiaries from two different locations in central Chile. Fur...

journal_title：Virus genes

authors： Barriga GP,Cifuentes-Muñoz N,Rivera PA,Gutierrez M,Shmaryahu A,Valenzuela PD,Engel EA

更新日期：2012-12-01 00:00:00

abstract：:We previously identified a large homologous region (hr), hycu-hr6, in the genome of the Hyphantria cunea nucleopolyhedrovirus (HycuNPV) and suggested that hycu-hr6 was the largest baculovirus promoter enhancer hr identified so far. In this study, we examined the enhancement activity of hycu-hr6 against two promoters f...

journal_title：Virus genes

authors： Felipe Alves CA,Ishikawa H,Ikeda M,Kobayashi M

更新日期：2009-12-01 00:00:00

abstract：:We evaluated the predicted biochemical properties of Gag proteins from a diverse group of feline immunodeficiency viruses (FIV) to determine how different evolutionary histories of virus and host have changed or constrained these important structural proteins. Our data are based on FIV sequences derived from domestic ...

journal_title：Virus genes

authors： Burkala E,Poss M

更新日期：2007-10-01 00:00:00

abstract：:In our transient expression assays, the IE180 and TK promoters were markedly suppressed by the EP0 of the pseudorabies virus strains Ea and Fa (EP0/Ea, EP0/Fa). This is in contrast with the transactivating activity of EP0 from strain YS-81 (EP0/YS-81) in previous studies. Amino acid sequence alignment revealed several...

journal_title：Virus genes

authors： Guo H,Zhou R,Xi Y,Xiao S,Chen H

更新日期：2009-04-01 00:00:00

abstract：:Proteins harbor domains or short linear motifs, which facilitate their functions and interactions. Finding functional motifs in protein sequences could predict the putative cellular roles or characteristics of hypothetical proteins. In this study, we present Shetti-Motif, which is an interactive tool to (i) map UniPro...

journal_title：Virus genes

authors： Sobhy H

更新日期：2017-04-01 00:00:00

abstract：:The complete nucleotide sequence of mumps virus isolated in Korea, Dg1062/Korea/98 (Dg1062), was determined. As other mumps viruses, its genome was to be 15,384 nucleotides (nts) in length and encoded seven proteins. The both 5' and 3' ends were confirmed to be 55 and 24 nts by RACE method, respectively. The full-leng...

journal_title：Virus genes

authors： Lee JY,Na BK,Lee HD,Chang SW,Kim KA,Kim JH,Cho HW,Kim J,Kang C

更新日期：2004-03-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome (PRRS) is a swine disease of major economic importance that causes reproductive and respiratory problems in pigs. In the present study, one strain of porcine reproductive and respiratory syndrome virus (PRRSV) was isolated in Xinjiang province, Northwest China, designated ...

journal_title：Virus genes

authors： Xia J,Chen S,Huang J,Ma W,Du W,Yang X,Liu Y,Yan G

更新日期：2015-02-01 00:00:00

abstract：:The baculovirus system was used to express the X protein of human hepatitis B virus (HBV). The X open reading frames (X ORFs) from cloned viral DNA of the HBV subtypes ayw and adr were introduced into the genome of Autographa californica nuclear polyhedrosis virus (AcNPV). The HBV-DNA of subtype adr derived from a hep...

journal_title：Virus genes

authors： Klein R,Schröder CH,Zentgraf H

更新日期：1991-04-01 00:00:00

abstract：:We performed whole genome sequencing of 22 H9N2 avian influenza viruses (AIV) isolated from domestic laying hens on farms between 2005 and 2008, and compared the sequences with viruses previously reported in Asia. A previous study revealed that two antigenically distinct sublineages were established within the MS96 li...

journal_title：Virus genes

authors： Lee CH,Byun SH,Lee YJ,Mo IP

更新日期：2012-08-01 00:00:00

abstract：:The eight gene segments of avian influenza virus (AIV) reassort frequently and rapidly to generate novel genotypes and subtypes that are transmissible to a broad range of hosts. There is evidence that AIV can have a restricted host range and can segregate in space and time. Host-virus relationships at the species, geo...

journal_title：Virus genes

authors： Girard YA,Runstadler JA,Aldehoff F,Boyce W

更新日期：2012-06-01 00:00:00

abstract：:Genetic analysis indicated that the pandemic influenza strains derived from wild aquatic birds harbor viruses of 15 hemagglutinin (HA) and 9 neuraminidase (NA) antigenic subtypes. Surveillance studies have shown that H9N2 subtype viruses are worldwide in domestic poultry and could infect mammalian species, including h...

journal_title：Virus genes

authors： Liu JH,Okazaki K,Shi WM,Kida H

更新日期：2003-12-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) reactivates from a small fraction of latently infected neurons in vivo and neuronally differentiated (ND), quiescently infected (QIF)-PC12 cells in vitro. This may be the result of reactivation initiating in only a few cells, or reactivation followed by premature termination of the ...

journal_title：Virus genes

authors： Danaher RJ,Jacob RJ,Miller CS

更新日期：2006-10-01 00:00:00

abstract：:In 2009, a bovine parainfluenza virus (BPIV3), named as NM09, was isolated using MDBK cell culture from the nasal swabs of normal cattle in China. The NM09 isolate was characterized by RT-PCR and nucleotide sequence analysis. Its complete genome was 15,456 nucleotides in length. Similar to other sequenced PIV strains,...

journal_title：Virus genes

authors： Wen YJ,Shi XC,Wang FX,Wang W,Zhang SQ,Li G,Song N,Chen LZ,Cheng SP,Wu H

更新日期：2012-12-01 00:00:00

abstract：:Pseudorabies virus (PRV) belongs to the Alphaherpesvirinae subfamily of Herpesviridae. PRV-induced pseudorabies is a highly contagious disease that has caused huge economic losses to the global swine industry. The PRV gE/gI gene deletion vaccine strain (Fa ΔgE/gI strain) constructed from the PRV Fa wild-type strain wa...

journal_title：Virus genes

authors： Liu X,Zhou Y,Luo Y,Chen Y

更新日期：2020-08-01 00:00:00

abstract：:African monkeys are resistant to HIV-1 infection due to intrinsic restriction mechanisms found in their cells. However, although they can be infected by monkey-adapted modified HIV-1 particles that are designed to overcome known restriction factors, virus numbers drop to undetectable levels in immunocompetent animals....

journal_title：Virus genes

authors： Özdemir S,Şengez B,Arslanoğlu A

更新日期：2020-04-01 00:00:00

abstract：:Chicken anemia virus (CAV) is the pathogen of chicken infectious anemia. To clarify the driving force in CAV evolution, we have detected positive selection in the structural protein gene VP1 by using maximum-likelihood models. Strong evidence was found that VP1 proteins were subject to the high rates of positive selec...

journal_title：Virus genes

authors： Wang D,Fan W,Han GZ,He CQ

更新日期：2009-04-01 00:00:00

abstract：:The red imported fire ant (Solenopsis invicta) escaped its natural enemies when it was introduced into North America in the 1930s from South America. US efforts have focused on discovery of natural enemies, like viruses, to provide sustainable control of the ant. Nine new virus genomes were sequenced from the invasive...

journal_title：Virus genes

authors： Valles SM,Rivers AR

更新日期：2019-06-01 00:00:00

abstract：:The Tahyna virus (TAHV) is an important human pathogen in the Bunyaviridae family. To date, only the S and M segments of this virus have been sequenced, but the sequence of the L segment hasn't been established yet. In this study, we sequenced 963 nucleotides of the L segment of TAHV, comprising pre-motif A and motif ...

journal_title：Virus genes

authors： Quinan BR,de Brito Magalhães CL,Novaes RF,Dos Santos JR,Kroon EG,Bonjardim CA,Ferreira PC

更新日期：2008-06-01 00:00:00

abstract：:For millions of years viruses have adapted strategies to interfere with the immune defense of the host, which in turn has to deal with this challenge. In general the antiviral defense remains one step behind the pathogen. To achieve this strategic advantage large DNA-containing Viruses encode cellular homologues that ...

journal_title：Virus genes

authors： Raftery M,Müller A,Schönrich G

更新日期：2000-01-01 00:00:00