Abstract:
:The broad distribution and prevalence of H3 subtype influenza viruses in avian and mammalian hosts constitutes a global threat to both human and veterinary health. In this present study, six H3N8 influenza viruses isolated from domestic ducks during 2004-2005 in northern China were genetically and phylogenetically characterized. Sequence analysis showed that HA, NA, and M genes of all the six H3N8 isolates had a close relationship with those of Equine/Jilin/1/89 (H3N8) virus, which once caused outbreak in equine populations in northern China. The PB2 and PA genes of the viruses possessed the highest similarities with highly pathogenic avian H5N1 influenza viruses currently circulating in this region. These findings emphasize the importance of avian influenza virus surveillance in this region for understanding the genesis and emergency of novel reassortants with pandemic potential.
journal_name
Virus Genesjournal_title
Virus genesauthors
Pu J,Liu QF,Xia YJ,Fan YL,Brown EG,Tian FL,Liu JHdoi
10.1007/s11262-008-0300-7subject
Has Abstractpub_date
2009-02-01 00:00:00pages
136-42issue
1eissn
0920-8569issn
1572-994Xjournal_volume
38pub_type
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