Genetic analysis of H3 subtype influenza viruses isolated from domestic ducks in northern China during 2004-2005.

Abstract:

:The broad distribution and prevalence of H3 subtype influenza viruses in avian and mammalian hosts constitutes a global threat to both human and veterinary health. In this present study, six H3N8 influenza viruses isolated from domestic ducks during 2004-2005 in northern China were genetically and phylogenetically characterized. Sequence analysis showed that HA, NA, and M genes of all the six H3N8 isolates had a close relationship with those of Equine/Jilin/1/89 (H3N8) virus, which once caused outbreak in equine populations in northern China. The PB2 and PA genes of the viruses possessed the highest similarities with highly pathogenic avian H5N1 influenza viruses currently circulating in this region. These findings emphasize the importance of avian influenza virus surveillance in this region for understanding the genesis and emergency of novel reassortants with pandemic potential.

journal_name

Virus Genes

journal_title

Virus genes

authors

Pu J,Liu QF,Xia YJ,Fan YL,Brown EG,Tian FL,Liu JH

doi

10.1007/s11262-008-0300-7

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

136-42

issue

1

eissn

0920-8569

issn

1572-994X

journal_volume

38

pub_type

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