Abstract:
:A daily variation of tryptophan hydroxylase (TrH) activity was observed in the raphe dorsalis (RD), raphe centralis (RC) and striatum (St) of 3 inbred strains of mice (BALB/c, C57BL/6, C57BR) and of the reciprocal hybrids obtained from Balb/c and C57BL6. Significant differences of the characteristics of these rhythms have been found in the same strain between different structures and for the same structure between different strains. In RD and RC hybridization led to less defined daily variations which, in the striatum, remained well synchronized and could be controlled by a dominant genetic mechanism part. These results help to discuss evidence for selective control mechanisms of regulation responsible for daily variation of TrH in the 5-HT cell bodies and terminals and their relative independence.
journal_name
Brain Resjournal_title
Brain researchauthors
Natali JP,McRae-Degueurce A,Chouvet G,Pujol JFdoi
10.1016/0006-8993(80)90322-4subject
Has Abstractpub_date
1980-06-02 00:00:00pages
191-203issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(80)90322-4journal_volume
191pub_type
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