Genetic studies of daily variations of first-step enzymes of monoamines metabolism in the brain of inbred strains of mice and hybrids. I. Daily variations of tryptophan hydroxylase activity in the nuclei raphe dorsalis, raphe centralis and in the striatum

Abstract:

:A daily variation of tryptophan hydroxylase (TrH) activity was observed in the raphe dorsalis (RD), raphe centralis (RC) and striatum (St) of 3 inbred strains of mice (BALB/c, C57BL/6, C57BR) and of the reciprocal hybrids obtained from Balb/c and C57BL6. Significant differences of the characteristics of these rhythms have been found in the same strain between different structures and for the same structure between different strains. In RD and RC hybridization led to less defined daily variations which, in the striatum, remained well synchronized and could be controlled by a dominant genetic mechanism part. These results help to discuss evidence for selective control mechanisms of regulation responsible for daily variation of TrH in the 5-HT cell bodies and terminals and their relative independence.

journal_name

Brain Res

journal_title

Brain research

authors

Natali JP,McRae-Degueurce A,Chouvet G,Pujol JF

doi

10.1016/0006-8993(80)90322-4

subject

Has Abstract

pub_date

1980-06-02 00:00:00

pages

191-203

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(80)90322-4

journal_volume

191

pub_type

杂志文章
  • Rapid changes in extracellular glucose levels and blood flow in the striatum of the freely moving rat.

    abstract::The dynamics of regional cerebral blood flow and brain extracellular glucose were studied in the freely moving rat. These two variables were measured in the striatum during and following both mild tail pinch and restraint stress. Blood flow was monitored using a refinement of the hydrogen clearance technique that allo...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90373-u

    authors: Fellows LK,Boutelle MG

    更新日期:1993-02-26 00:00:00

  • Selective impairment of declarative memory following stimulation of dentate gyrus granule cells: a naloxone-sensitive effect.

    abstract::Albino rats received 10 s of sub-seizure electrical stimulation applied to the dentate gyrus granule cells immediately after acquisition of information on trial 1 of a 2-trial radial maze spatial memory task. Granule cell stimulation selectively reduced the probability of accessing information held in declarative memo...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)90166-5

    authors: Collier TJ,Routtenberg A

    更新日期:1984-09-24 00:00:00

  • Neuroprotective effects of MHY908, a PPAR α/γ dual agonist, in a MPTP-induced Parkinson's disease model.

    abstract::Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and are considered promising therapeutic targets in several neurodegenerative diseases. A number of PPAR agonists have been shown to have neuroprotective properties in the presence of oxidative stress, neuroinflammatory response, and apoptosis i...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2018.09.036

    authors: Lee Y,Cho JH,Lee S,Lee W,Chang SC,Chung HY,Moon HR,Lee J

    更新日期:2019-02-01 00:00:00

  • Effect of MK-801 on endogenous dopamine release in vivo.

    abstract::The effect of MK-801 on striatal dopamine (DA) release was investigated by using an in vivo microdialysis technique in the freely moving rat. Systemic injection of MK-801 (0.25, 0.5, 1, 2 mg/kg, i.p.) reduced the extracellular level of DA significantly and produced no change in the level of 3,4-dihydroxyphenylacetic a...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90197-j

    authors: Kashihara K,Hamamura T,Okumura K,Otsuki S

    更新日期:1990-09-24 00:00:00

  • The effects of monoamine uptake inhibitors and methamphetamine on neostriatal 6-hydroxydopamine (6-OHDA) formation, short-term monoamine depletions and locomotor activity in the rat.

    abstract::Monoamine uptake inhibitors block the neurotoxic effects of methamphetamine (MA) upon dopaminergic and serotonergic neurons in the rat. The neurotoxic effects of MA upon dopaminergic neurons have previously been suggested to be mediated via formation of 6-hydroxydopamine (6-OHDA) from endogenous stores of dopamine (DA...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90889-j

    authors: Marek GJ,Vosmer G,Seiden LS

    更新日期:1990-05-14 00:00:00

  • Do the substance P-ergic vagus afferents in cats reinnervate the deafferented superior cervical ganglion?

    abstract::By ligating specific nerves in the cat, the central processes of the nodose ganglion (NG) cells containing substance P-like immunoreactive materials were shown, immunohistochemically, to run through the cross-anastomosis made between the cranial end of the NG and the caudal end of the superior cervical ganglion (SCG),...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)90811-9

    authors: Hayashi H,Ohsumi K,Fujiwara M,Mizuno N

    更新日期:1983-06-27 00:00:00

  • Immunohistochemical expression of doublecortin in the human cerebrum: comparison of normal development and neuronal migration disorders.

    abstract::Immunohistochemical expression of the doublecortin (DCX) gene product was investigated in cerebral cortices from 33 normal developing human, aged 9 gestational weeks (GW) to 29 years, and from 26 patients with various neuronal migration disorders, aged 19 GW to 34 years. DCX immunoreactivity was detected predominantly...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02099-0

    authors: Qin J,Mizuguchi M,Itoh M,Takashima S

    更新日期:2000-04-28 00:00:00

  • Social attraction between rats in open field: long-term consequences of kindled seizures.

    abstract::Kindling of the amygdaloid complex in rats results in an enhanced emotionality frequently expressed by an elevated anxiety and defensive attitude toward other animals. Defensive attitude may have important consequences in social context and if tested in a large space it may eventually lead to social withdrawal. To tes...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(01)03162-6

    authors: Haimovici A,Wang Y,Cohen E,Mintz M

    更新日期:2001-12-13 00:00:00

  • Oxygen-induced apoptosis in PC12 cells with special reference to the role of Bcl-2.

    abstract::We previously reported that PC12h cells are killed by a high oxygen atmosphere. In this study, we further characterized this oxygen-induced cell death and found apoptotic features, as follows. Firstly, chromatin condensation was observed in cells cultured in a 50% O2 atmosphere. Secondly, cycloheximide and cordycepin,...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(96)00542-2

    authors: Kubo T,Enokido Y,Yamada M,Oka T,Uchiyama Y,Hatanaka H

    更新日期:1996-09-16 00:00:00

  • L-type calcium channels modulate glutamate-driven bursting activity in the nucleus accumbens in vivo.

    abstract::The majority of adult nucleus accumbens medium spiny neurons exhibit a bistable membrane potential that fluctuates between a relatively hyperpolarized (Down) state (average=-76 mV) and a less hyperpolarized (Up) state (average=-60 mV) near firing threshold. During in vivo extracellular recordings from nucleus accumben...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02868-7

    authors: Cooper DC,White FJ

    更新日期:2000-10-13 00:00:00

  • Paeoniflorin attenuates Aβ1-42-induced inflammation and chemotaxis of microglia in vitro and inhibits NF-κB- and VEGF/Flt-1 signaling pathways.

    abstract::Alzheimer׳s disease (AD) is a neurodegenerative disease with elusive pathogenesis, which accounts for most cases of dementia in the aged population. It has been reported that persistent inflammatory responses and excessive chemotaxis of microglia stimulated by beta-amyloid (Aβ) oligomers in the brain may accelerate th...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2015.05.035

    authors: Liu H,Wang J,Wang J,Wang P,Xue Y

    更新日期:2015-08-27 00:00:00

  • Effects on the growth of damaged ganglion cell axons after peripheral nerve transplantation in adult hamsters.

    abstract::After transplantation of autologous sciatic nerve segments into the retina of adult hamsters for 1-2 months, retrograde labelling with horseradish peroxidase demonstrated a population of ganglion cells situated peripheral to the graft. If an additional lesion was placed between the insertion of the graft and the optic...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91203-5

    authors: So KF,Xiao YM,Diao YC

    更新日期:1986-07-02 00:00:00

  • Intracerebroventricular saccharide infusions inhibit thirst induced by systemic hypertonicity.

    abstract::The effect of intracerebroventricular (i.c.v.) infusion of various iso- and hypertonic saccharide solutions on water intake stimulated by intracarotid (i.c.) infusion of hypertonic NaCl was studied in sheep. Without an i.c.v. infusion, water intake during a 10-min period following an i.c. infusion of 4 M NaCl (1.4 ml/...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)91006-8

    authors: Park R,Denton DA,McKinley MJ,Pennington G,Weisinger RS

    更新日期:1989-07-24 00:00:00

  • The behavioural consequences of dissociating the spatial directions of eye and arm movements.

    abstract::Many of our daily movements use visual information to guide our arms toward objects of interest. Typically, these visually guided movements involve first focusing our gaze on the intended target and then reaching toward the direction of our gaze. The literature on eye-hand coordination provides a great deal of evidenc...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.05.057

    authors: Gorbet DJ,Sergio LE

    更新日期:2009-08-11 00:00:00

  • The effects of stimulation and lesion of raphe nuclei on luteinizing hormone release in estrogen-progesterone-treated ovariectomized rats.

    abstract::A study was made of the effects of electrochemically stimulating (ECS) and destroying the midbrain dorsal and median raphe nuclei on the estrogen-progesterone- (EP) induced surge of pituitary LH release in ovariectomized rats. ECS and lesions were produced simultaneously with anodal direct current through a chronicall...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90006-8

    authors: Waloch M,Gilman D,Whitmoyer D,Sawyer CH

    更新日期:1981-08-03 00:00:00

  • Output organization of the feline entopeduncular and subthalamic nuclei.

    abstract::Entopeduncular nucleus (EPN) cells which project to thalamic and non-thalamic sites were identified by antidromic discharge. Each population of cells, projecting to the ventral anterior nucleus of the thalamus (VA), centrum medianum (CM), the lateral habenula (LHB), and the pedunculopontine nucleus (PP), was distribut...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(78)90993-9

    authors: Larsen KD,Sutin J

    更新日期:1978-11-17 00:00:00

  • Induction of NMDA receptor-independent long-term potentiation (LTP) in visual cortex of adult rats.

    abstract::The aim of this study was to examine: (1) whether long-term potentiation (LTP) can be induced in slices from adult rat visual cortex under conditions where inhibition is not antagonized, and (2) the role of N-methyl-D-aspartate (NMDA) receptors in its induction. The field potential elicited in layer III in response to...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)90891-c

    authors: Aroniadou VA,Teyler TJ

    更新日期:1992-07-03 00:00:00

  • Microwave irradiated collagen tubes as a better matrix for peripheral nerve regeneration.

    abstract::Collagen is one of the best materials used for nerve guide preparation due to its biocompatibility and desirable tensile strength. In this work, we have compared regeneration and functional reinnervation after sciatic nerve resection with bioresorbable crosslinked collagen guides in 10 mm gap. The crosslinking was car...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2005.03.022

    authors: Ahmed MR,Vairamuthu S,Shafiuzama M,Basha SH,Jayakumar R

    更新日期:2005-06-07 00:00:00

  • Analysis of fast axoplasmic transport in nerve ligation and adriamycin-induced neuronal perikaryon lesions.

    abstract::Fast axoplasmic transport was examined in experimental nerve ligation and adriamycin-induced neuronal perikaryon lesions. Animals were sacrificed at precisely 3 and 4 h following the injection of [3H]leucine. In single ligated nerves, the 3 and 4 h down-flow rates, which include the time for neuronal processing of lab...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(79)90730-3

    authors: Sahenk Z,Mendell JR

    更新日期:1979-07-27 00:00:00

  • Distribution of glutamine synthetase and glial fibrillary acidic protein and correlation of glutamine synthetase with glutamate decarboxylase in different regions of the rat central nervous system.

    abstract::The concentration of soluble glial fibrillary acidic (GFA) protein and the specific activity of glutamine synthetase (GS) were estimated in 11 central nervous system (CNS) regions of the 90-day-old rat. Marked differences were observed in the regional distribution of these astrocyte marker proteins. The striatum and s...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90708-5

    authors: Patel AJ,Weir MD,Hunt A,Tahourdin CS,Thomas DG

    更新日期:1985-04-01 00:00:00

  • Quantitative correlation between tetanus-induced decreases in extracellular calcium and LTP.

    abstract::Decreases in the extracellular calcium concentration ([Ca2+]o), induced by tetanization of the Schaffer collaterals in rat hippocampal slices, were measured by means of Ca2+-sensitive microelectrodes. The amount of long term potentiation (LTP) of the evoked field potentials, induced by this tetanus, was determined. A ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)90798-6

    authors: Melchers BP,Pennartz CM,Wadman WJ,Lopes da Silva FH

    更新日期:1988-06-28 00:00:00

  • Electrophysiological characteristics of cholinergic and non-cholinergic neurons in the rat medial septum-diagonal band complex.

    abstract::We examined the electrophysiological properties of cholinergic and non-cholinergic neurons in the medial septum-diagonal band complex (MSDB) of the rat in the in vitro slice preparation. Cells were identified electrophysiologically, filled with Lucifer yellow, fixed and processed for immunohistochemistry with fluoresc...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)91106-q

    authors: Markram H,Segal M

    更新日期:1990-04-09 00:00:00

  • Spread of scrapie agent to the central nervous system: study of a rat model.

    abstract::Invasion of scrapie agent into the central nervous system (CNS) was studied in rats following intracerebral and peripheral inoculation, the latter by injection into intact or transected sciatic nerve. Comparison of sleep-wakefulness alterations, neuropathological features, and time lag of electroencephalographic and c...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90048-x

    authors: Bassant MH,Baron H,Gumpel M,Cathala F,Court L

    更新日期:1986-09-24 00:00:00

  • SPARC, an extracellular matrix glycoprotein containing the follistatin module, is expressed by astrocytes in synaptic enriched regions of the adult brain.

    abstract::Although extracellular matrix (ECM) glycoproteins play important roles in neural development, their levels are generally believed to decrease in the adult brain. Immunohistochemical analysis indicates that the anti-adhesive ECM glycoprotein SPARC/osteonectin, which contains a follistatin 'module,' is expressed in the ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00101-u

    authors: Mendis DB,Malaval L,Brown IR

    更新日期:1995-04-03 00:00:00

  • Modulation of dopamine uptake by nitric oxide in cultured mesencephalic neurons.

    abstract::Strong evidence obtained from in vivo and ex-vivo studies suggests the existence of interaction between dopaminergic and nitrergic systems. Some of the observations suggest a possible implication of nitric oxide (NO) in dopamine (DA) uptake mechanism. The present work investigated the interaction between both systems ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.12.054

    authors: Salum C,Raisman-Vozari R,Michel PP,Gomes MZ,Mitkovski M,Ferrario JE,Ginestet L,Del Bel EA

    更新日期:2008-03-10 00:00:00

  • Nitric oxide involvement in the trigeminal hyperalgesia in diabetic rats.

    abstract::Trigeminal hyperalgesia frequently appears in diabetic neuralgia altering the transmission of orofacial sensory information. This study was designed to explore the effects of trigeminal hyperalgesia in streptozotocin-induced diabetes monitoring the expression of nitric oxide synthase in the trigeminal ganglion cells. ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02235-6

    authors: Rodella L,Rezzani R,Corsetti G,Bianchi R

    更新日期:2000-05-19 00:00:00

  • Maternal and genetic factors in stress-resilient and -vulnerable rats: a cross-fostering study.

    abstract::Early environmental factors can modulate the development of the hypothalamic-pituitary-adrenal (HPA) axis response to stress, together with subsequent brain functions and emotional behaviors. Two rat strains, Sprague-Dawley (SD) and Fischer 344 (F344), are known to exhibit differences in HPA axis reactivity and anxiet...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.11.070

    authors: Uchida S,Hara K,Kobayashi A,Otsuki K,Hobara T,Yamagata H,Watanabe Y

    更新日期:2010-02-26 00:00:00

  • Insulin inhibits pyramidal neurons in hippocampal slices.

    abstract::Recent studies have confirmed the presence of insulin receptors in the rat brain although their function has still not been well defined. The present study explores the possibility that insulin receptors in the brain can alter or contribute to central neurotransmission. Insulin caused a dose-dependent inhibition of hi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)91028-x

    authors: Palovcik RA,Phillips MI,Kappy MS,Raizada MK

    更新日期:1984-08-20 00:00:00

  • Gangliosides modulate Schwann cell proliferation and morphology.

    abstract::We examined the effect of gangliosides on Schwann cell cultures isolated from neonatal rat sciatic nerves. Addition of gangliosides (GM1, GM3, and ganglioside mixture) at concentrations between 0.25 and 2 mg/ml significantly diminished both the baseline rate of proliferation of the Schwann cells and their response to ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)90442-8

    authors: Sobue G,Taki T,Yasuda T,Mitsuma T

    更新日期:1988-12-06 00:00:00

  • PACAP-containing intrapineal nerve fibers originate predominantly in the trigeminal ganglion: a combined retrograde tracing- and immunohistochemical study of the rat.

    abstract::Pituitary adenylate-cyclase activating polypeptide (PACAP) is a neuropeptide originally isolated from the hypothalamus and located in many neuronal systems in both the central and peripheral nervous system. PACAP is also found in nerve fibers innervating the pineal gland, where it stimulates the secretion of the pinea...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(03)03127-5

    authors: Møller M,Baeres FM

    更新日期:2003-09-12 00:00:00