Quantification of rigidity in Parkinson's disease.

abstract：:We attempted to estimate in living adherent epithelial alveolar cells, the degree of structural and mechanical heterogeneity by considering two individualized cytoskeleton components, i.e., a submembranous "cortical" cytoskeleton and a "deep" cytoskeleton (CSK). F-actin structure characterizing each CSK component was ...

journal_title：Annals of biomedical engineering

authors： Laurent VM,Fodil R,Cañadas P,Féréol S,Louis B,Planus E,Isabey D

更新日期：2003-11-01 00:00:00

abstract：:Experimental and diagnostic procedures like distension of a balloon catheter, bougie, and esophagogastroduodenoscopy can induce shear deformation in the esophageal wall. However, the shear modulus of the esophagus is yet unknown. The aim of this study was to determine the esophageal shear modulus and its dependence on...

journal_title：Annals of biomedical engineering

authors： Yang J,Liao D,Zhao J,Gregersen H

更新日期：2004-09-01 00:00:00

abstract：:Maintenance of movement accuracy relies on motor learning, by which prior errors guide future behavior. One aspect of this learning process involves the accurate generation of predictions of movement outcome. These predictions can, for example, drive anticipatory movements during a predictive-saccade task. Predictive ...

journal_title：Annals of biomedical engineering

authors： Wong AL,Shelhamer M

更新日期：2013-08-01 00:00:00

abstract：:There is a high incidence of low back pain (LBP) associated with occupations requiring sustained and/or repetitive lumbar flexion (SLF and RLF, respectively), which cause creep of the viscoelastic tissues. The purpose of this study was to determine the effect of creep on lumbar biomechanics and facet joint capsule (FJ...

journal_title：Annals of biomedical engineering

authors： Little JS,Khalsa PS

更新日期：2005-03-01 00:00:00

abstract：:Acute cerebral ischemic events and thrombosis are associated with the rupture/erosion of carotid atherosclerotic plaques. The aim of the present study was to determine the impact of calcification deposition on the wall shear stress (WSS) and stresses within the plaques using 3D fluid-structure interaction (FSI) models...

journal_title：Annals of biomedical engineering

authors： Benitez J,Fontanarosa D,Wang J,Paritala PK,McGahan T,Lloyd T,Li Z

更新日期：2020-10-20 00:00:00

abstract：:The current paradigm in tissue engineering is that "full regeneration" or "total replacement" of normal tissue is required in order to restore joint function. However, there is considerable evidence that suggests that targets other than "normality" may actually be required for tissue substitutes. Sometimes "less than ...

journal_title：Annals of biomedical engineering

authors： Frank CB,Shrive NG,Boorman RS,Lo IK,Hart DA

更新日期：2004-03-01 00:00:00

abstract：:A flow diverter (FD) is a flexible, densely braided stent-mesh device placed endoluminally across an intracranial aneurysm to induce its thrombotic occlusion. FD treatment planning using computational virtual stenting and flow simulation requires accurate representation of the expanded FD geometry. We have recently de...

journal_title：Annals of biomedical engineering

authors： Ma D,Dumont TM,Kosukegawa H,Ohta M,Yang X,Siddiqui AH,Meng H

更新日期：2013-10-01 00:00:00

abstract：:A method of investigating head acceleration and intracranial dynamics from stick impacts in girls' and women's lacrosse was developed using headform impact experiments and a finite element head model. Assessing the likelihood of head injury due to stick-head impacts is of interest in girls' and women's lacrosse due to...

journal_title：Annals of biomedical engineering

authors： Morse JD,Franck JA,Wilcox BJ,Crisco JJ,Franck C

更新日期：2014-12-01 00:00:00

abstract：:This study aimed to quantify the elongation patterns of the collateral ligaments following TKA during functional activities of daily living. Using mobile video-fluoroscopy to capture radiographic images of the knee in a group of six patients, each with an ultra-congruent knee implant, tibiofemoral kinematics were reco...

journal_title：Annals of biomedical engineering

authors： Hosseini Nasab SH,Smith CR,Schütz P,Damm P,Trepczynski A,List R,Taylor WR

更新日期：2020-04-01 00:00:00

abstract：:The multiphoton fluorescence recovery after photobleaching (MP-FRAP) technique has been developed to measure the three-dimensional (3D) solute diffusion within biological systems. However, current 3D MP-FRAP models are based on isotropic diffusion and spatial domain analysis. The 3D anisotropic diffusion and frequency...

journal_title：Annals of biomedical engineering

authors： Shi C,Cisewski SE,Bell PD,Yao H

更新日期：2014-03-01 00:00:00

abstract：:For treatment of complex congenital heart disease, computer simulation using a three-dimensional heart model may help to improve outcomes by enabling detailed preoperative evaluations. However, no highly integrated model that accurately reproduces a patient's pathophysiology, which is required for this simulation has ...

journal_title：Annals of biomedical engineering

authors： Kariya T,Washio T,Okada JI,Nakagawa M,Watanabe M,Kadooka Y,Sano S,Nagai R,Sugiura S,Hisada T

更新日期：2020-06-01 00:00:00

abstract：:Congenital heart disease is the leading cause of infant death in the United States with over 36,000 newborns affected each year. Despite this growing problem there are few mechanical circulatory support devices designed specifically for pediatric and neonate patients. Previous research has been done investigating pedi...

journal_title：Annals of biomedical engineering

authors： Good BC,Deutsch S,Manning KB

更新日期：2016-04-01 00:00:00

abstract：:Radiation applied for therapy and diagnostics damages molecular/atomic couples of biotissues, bones being among them. As a result, electron peculiarities and mechanical behavior of the latter are altered. Correlation between strength of the irradiated bone and its electron features explored due to photo- and exoelectr...

journal_title：Annals of biomedical engineering

authors： Dekhtyar Y

更新日期：2001-12-01 00:00:00

abstract：:Long-range dependency has been found in most rhythmic motor signals. The origin of this property is unknown and largely debated. There is a controversy on the influence of voluntary control induced by requiring a pre-determined pace such as asking subjects to step to a metronome. We studied the cycle duration variabil...

journal_title：Annals of biomedical engineering

authors： Warlop TB,Bollens B,Crevecoeur F,Detrembleur C,Lejeune TM

更新日期：2013-08-01 00:00:00

abstract：:The temporal and spatial distribution of coronary blood flow, pressure, and volume are determined by the branching pattern and three-dimensional (3-D) geometry of the coronary vasculature, and by the mechanics of heart wall and vascular tone. Consequently, a realistic simulation of coronary blood flow requires, as a f...

journal_title：Annals of biomedical engineering

authors： Kaimovitz B,Lanir Y,Kassab GS

更新日期：2005-11-01 00:00:00

abstract：:The influence of scaffold compliance on blood vessel tissue engineering remains unclear and compliance mismatch issues are important to an in vivo tissue-engineering approach. We have designed and constructed a modular bioreactor system that is capable of imparting pulsatile fluid flow while simultaneously measuring v...

journal_title：Annals of biomedical engineering

authors： Webb AR,Macrie BD,Ray AS,Russo JE,Siegel AM,Glucksberg MR,Ameer GA

更新日期：2007-08-01 00:00:00

abstract：:In recent years, advances in computing power and computational methods have made it possible to perform detailed simulations of the coronary artery stenting procedure and of related virtual tests of performance (including fatigue resistance, corrosion and haemodynamic disturbance). Simultaneously, there has been a gro...

journal_title：Annals of biomedical engineering

authors： Bressloff NW,Ragkousis G,Curzen N

更新日期：2016-02-01 00:00:00

abstract：:Impedance cardiography has not achieved popularity in the Intensive Care Unit (ICU) to date probably because of the limitations in technique and interpretation associated with the altered physiology of critically ill patients, and also because of interference from other machinery in the ICU. The current climate of que...

journal_title：Annals of biomedical engineering

authors： Fuller H,Raskob G,ter Keurs H,Hull R

更新日期：1989-01-01 00:00:00

abstract：:A mathematical model of heat, water and soluble gas exchange in the airways and alveoli was used to predict the location of soluble gas exchange in the lung. A previously published model of heat, water and soluble gas exchange in the airways was improved by incorporating anatomical data on the airway wall to better de...

journal_title：Annals of biomedical engineering

authors： Anderson JC,Babb AL,Hlastala MP

更新日期：2003-12-01 00:00:00

abstract：:A role for mechanical stimulation in the control of cell fate has been proposed and mechanical conditioning of mesenchymal stem cells (MSCs) is of interest in directing MSC behavior for tissue engineering applications. This study investigates strain-induced differentiation and proliferation of MSCs, and investigates t...

journal_title：Annals of biomedical engineering

authors： Kearney EM,Farrell E,Prendergast PJ,Campbell VA

更新日期：2010-05-01 00:00:00

abstract：:Arteries are composed of multiple constituents that endow the wall with proper structure and function. Many vascular diseases are associated with prominent mechanical and biological alterations in the wall constituents. In this study, planar biaxial tensile test data of elastase-treated porcine aortic tissue (Chow et ...

journal_title：Annals of biomedical engineering

authors： Zeinali-Davarani S,Chow MJ,Turcotte R,Zhang Y

更新日期：2013-07-01 00:00:00

abstract：:In this paper, a novel cell stretcher design that mimics the real-time stretch of the heart wall is introduced. By culturing cells under stretched conditions that mimics the mechanical aspects of the native cardiac environment, better understanding on the role of biomechanical signaling on cell development can be achi...

journal_title：Annals of biomedical engineering

authors： Lau JJ,Wang RM,Black LD 3rd

更新日期：2014-05-01 00:00:00

abstract：:One of the major functions of the cardiovascular system is to deliver blood to the microcirculation where exchange of mass and energy can take place. In the present article, we will provide an overview of the state-of-the-art computational methods for modeling of red blood cell (RBC) rheology and dynamics in the micro...

journal_title：Annals of biomedical engineering

authors： Cristini V,Kassab GS

更新日期：2005-12-01 00:00:00

abstract：:We present a method of measuring force response of a single living cell, attached to a substrate, in situ, by a functionalized microelectromechanical systems sensor that applies local deformation on the cell. The sensor is a single crystal silicon microcantilever beam with prescribed shape and geometry, and is coated ...

journal_title：Annals of biomedical engineering

authors： Saif MT,Sager CR,Coyer S

更新日期：2003-09-01 00:00:00

abstract：:Gas transfer through hollow fiber membranes (HFMs) can be increased via fiber oscillation. Prior work, however, does not directly translate to present-day, full-scale artificial lungs. This in vitro study characterized the effects of HFM oscillations on oxygenation and hemolysis for a pediatric-sized HFM bundle. Effec...

journal_title：Annals of biomedical engineering

authors： Orizondo RA,Gino G,Sultzbach G,Madhani SP,Frankowski BJ,Federspiel WJ

更新日期：2018-05-01 00:00:00

abstract：:This study evaluates the use of artificial neural networks to estimate stroke volume from pre-processed, thoracic impedance plethysmograph signals from 20 healthy subjects. Standard back-propagation was used to train the networks, with Doppler stroke volume estimates as the desired output. The trained networks were th...

journal_title：Annals of biomedical engineering

authors： Mulavara AP,Timmons WD,Nair MS,Gupta V,Kumar AA,Taylor BC

更新日期：1998-07-01 00:00:00

abstract：:Cumulative exposure to head impacts during contact sports can elicit potentially deleterious brain white matter alterations in young athletes. Head impact exposure is commonly quantified using wearable sensors; however, these sensors tend to overestimate the number of true head impacts that occur and may obfuscate pot...

journal_title：Annals of biomedical engineering

authors： DiCesare CA,Green B,Yuan W,Diekfuss JA,Barber Foss KD,Dudley J,Qin Y,Wang P,Myer GD

更新日期：2020-12-01 00:00:00

abstract：:Clinicians generally assume that Medical Compression Stockings (MCS) work by reducing vein luminal diameter and, in this way, help to prevent blood pooling. Conflicting results have been reported however in the case of lower leg deep veins which call into question this hypothesis. The purpose of this contribution is t...

journal_title：Annals of biomedical engineering

authors： Rohan PY,Badel P,Lun B,Rastel D,Avril S

更新日期：2015-02-01 00:00:00

abstract：:This study was aimed at developing a physical model, supported by experimental observations, to describe the formation and growth of microbubbles seen in patients with mitral mechanical heart valves (MHV). This phenomenon, often referred to as high intensity transient signals (HITS), appears as bright, intense, high-v...

journal_title：Annals of biomedical engineering

authors： Rambod E,Beizaie M,Shusser M,Milo S,Gharib M

更新日期：1999-11-01 00:00:00

abstract：:Cell migration paths of mammary epithelial cells (expressing different versions of the promigratory tyrosine kinase receptor Her2/Neu) were analyzed within a bimodal framework that is a generalization of the run-and-tumble description applicable to bacterial migration. The mammalian cell trajectories were segregated i...

journal_title：Annals of biomedical engineering

authors： Potdar AA,Lu J,Jeon J,Weaver AM,Cummings PT

更新日期：2009-01-01 00:00:00