Human lumbar spine creep during cyclic and static flexion: creep rate, biomechanics, and facet joint capsule strain.

abstract：:Continuum-level finite element models (FEMs) of the humerus offer the ability to evaluate joint replacement designs preclinically; however, experimental validation of these models is critical to ensure accuracy. The objective of the current study was to quantify experimental full-field strain magnitudes within osteoar...

journal_title：Annals of biomedical engineering

authors： Kusins J,Knowles N,Columbus M,Oliviero S,Dall'Ara E,Athwal GS,Ferreira LM

更新日期：2020-12-01 00:00:00

abstract：:Recent advances in angioplasty have involved the application of polymer coatings to stent surfaces for purposes of drug delivery. Given the high levels of deformation developed in the plastic hinge of a stent during deployment, the achievement of an intact bond between the coating and the stent presents a significant ...

journal_title：Annals of biomedical engineering

authors： Hopkins CG,McHugh PE,McGarry JP

更新日期：2010-07-01 00:00:00

abstract：:Statistical methods are increasingly used in biomechanics for studying bone geometry, bone density distribution and function in the population. However, relating population-based bone variation to strain during activity is computationally challenging. Here, we describe a new method for calculating strain in a populati...

journal_title：Annals of biomedical engineering

authors： Ziaeipoor H,Taylor M,Martelli S

更新日期：2020-06-01 00:00:00

abstract：:Disease and injury perturb the balance of processes associated with inflammation and tissue remodeling, resulting in positive feedback loops, exacerbation of disease and compromised tissue repair. Conversely, under homeostatic healthy conditions, these processes are tightly regulated through the expansion and/or recru...

journal_title：Annals of biomedical engineering

authors： Glowacki AJ,Gottardi R,Yoshizawa S,Cavalla F,Garlet GP,Sfeir C,Little SR

更新日期：2015-03-01 00:00:00

abstract：:We have studied the interaction of high frequency jet ventilation with cardiovascular pressures and flows. Results in dogs show that the amplitude of all intrathoracic pressures and flows fluctuate with a frequency equal to the difference between the heart rate and ventilator rate. The magnitude of this amplitude vari...

journal_title：Annals of biomedical engineering

authors： Mitzner W,Gioia F,Weinmann GG,Robotham JL,Ehrlich W

更新日期：1987-01-01 00:00:00

abstract：:The pericellular matrix (PCM) is a region of tissue that surrounds chondrocytes in articular cartilage and together with the enclosed cells is termed the chondron. Previous studies suggest that the mechanical properties of the PCM, relative to those of the chondrocyte and the extracellular matrix (ECM), may significan...

journal_title：Annals of biomedical engineering

authors： Guilak F,Alexopoulos LG,Haider MA,Ting-Beall HP,Setton LA

更新日期：2005-10-01 00:00:00

abstract：:A novel apparatus for the multifaceted evaluation of artery function was developed. It measures endothelial and smooth muscle functions and the pressure-strain elastic modulus (E p). A rigid airtight chamber with an ultrasound probe was attached to the upper arm to manipulate the transmural pressure of the brachial ar...

journal_title：Annals of biomedical engineering

authors： Yaguchi T,Cong Y,Shimo K,Kurokawa T,Sugita S,Nagayama K,Masuda H,Matsumoto T

更新日期：2017-06-01 00:00:00

abstract：:Early stage changes in hypertensive arteries have a significant effect on the long-term adaptation of the arteries. Compared to the long-term adaptation, little is known about the early dimensional and functional changes in hypertensive arteries in the first few days of hypertension. To study the early stage changes i...

journal_title：Annals of biomedical engineering

authors： Han HC,Ku DN

更新日期：2001-06-01 00:00:00

abstract：:We propose a novel method to reconstruct the hypothetical geometry of the healthy vasculature prior to intracranial aneurysm (IA) formation: a Frenet frame is calculated along the skeletonization of the arterial geometry; upstream and downstream boundaries of the aneurysmal segment are expressed in terms of the local ...

journal_title：Annals of biomedical engineering

authors： Chen H,Selimovic A,Thompson H,Chiarini A,Penrose J,Ventikos Y,Watton PN

更新日期：2013-07-01 00:00:00

abstract：:Recent advances in fluorescence confocal endomicroscopy have allowed real-time identification of residual tumour cells on the walls of the cavity left by breast conserving surgery. However, it is difficult to systematically survey the surgical site because of the small imaging field-of-view of these probes, compounded...

journal_title：Annals of biomedical engineering

authors： Zuo S,Hughes M,Yang GZ

更新日期：2016-07-01 00:00:00

abstract：:The aim of this study was to establish in vitro bench-tests of left atrial appendage occlusion (LAAo) devices regarding tug force, radial force and sealing capacity. Two LAAo devices, namely the WATCHMAN™ and the Occlutech®, of three different sizes underwent testing in novel dedicated in vitro setups. Radial force wa...

journal_title：Annals of biomedical engineering

authors： Menne MF,Schrickel JW,Nickenig G,Al-Kassou B,Nelles D,Schmitz-Rode T,Steinseifer U,Sedaghat A

更新日期：2018-09-01 00:00:00

abstract：:Of the many models of peripheral nerve in the literature, essentially all have relied on experimentally derived values for the anisotropic resistivity of the nerve bundle interstitial space. This paper is a comprehensive mathematical analysis of the most referenced experiment for the longitudinal and radial resistivit...

journal_title：Annals of biomedical engineering

authors： Altman KW,Plonsey R

更新日期：1989-01-01 00:00:00

abstract：:Continued progress in the field of Brain Interface (BI) research has encouraged the rapid expansion of the BI community over the last two decades. As the number of BI researchers and organizations steadily increases, newer and more advanced technologies are constantly produced, evaluated, and reported. Though the BI c...

journal_title：Annals of biomedical engineering

authors： Jackson MM,Mason SG,Birch GE

更新日期：2006-05-01 00:00:00

abstract：:Conventional nanoporous hydrogels often lead to slow cartilage deposition by MSCs in 3D due to physical constraints and requirement for degradation. Our group has recently reported macroporous gelatin microribbon (μRB) hydrogels, which substantially accelerate MSC-based cartilage formation in vitro compared to convent...

journal_title：Annals of biomedical engineering

authors： Barati D,Gegg C,Yang F

更新日期：2020-07-01 00:00:00

abstract：:Patients with aortic stenosis present with calcium deposits on the native aortic valve, which can result in non-concentric expansion of Transcatheter Aortic Valve Replacement (TAVR) stents. The objective of this study is to evaluate whether eccentric deployment of TAVRs lead to turbulent blood flow and blood cell dama...

journal_title：Annals of biomedical engineering

authors： Gunning PS,Saikrishnan N,McNamara LM,Yoganathan AP

更新日期：2014-06-01 00:00:00

abstract：:The effects of tissue hydration and fixed charge density on hydraulic permeability and creep behavior of cartilaginous tissues have been investigated using the triphasic theory and finite element methods. The empirical model for hydraulic permeability of uncharged gels and Mackie and Meares (1955) model for ion diffus...

journal_title：Annals of biomedical engineering

authors： Gu WY,Yao H

更新日期：2003-11-01 00:00:00

abstract：:A computer-based feedback system has been developed to adjust the concentration of oxygen in the inspired gas of a patient under artificial respiration. The system uses a proportional plus integral controller and feedback of arterial oxygen saturation to adjust the inspired oxygen fraction. The effectiveness of the co...

journal_title：Annals of biomedical engineering

authors： Tehrani FT

更新日期：1992-01-01 00:00:00

abstract：:The induction of angiogenesis is a promising therapeutic strategy for the amelioration of peripheral arterial disease (PAD). This occlusive disease results in muscle ischemia, and neovascularization is a route to increasing the perfusion in the tissue. The vascular endothelial growth factor (VEGF) family of potent pro...

journal_title：Annals of biomedical engineering

authors： Mac Gabhann F,Ji JW,Popel AS

更新日期：2007-06-01 00:00:00

abstract：:Bending stiffness of passive-dynamic ankle-foot orthoses (PD-AFOs) is a functional characteristic thought to restore lost ankle function due to weakened plantar flexors. However, lower extremity impairment profiles of patients are seldom limited to plantar flexion weakness, and PD-AFO characteristics often influence g...

journal_title：Annals of biomedical engineering

authors： Arch ES,Stanhope SJ

更新日期：2015-02-01 00:00:00

abstract：:This article presents an overview of time-resolved (lifetime) fluorescence techniques used in biomedical diagnostics. In particular, we review the development of time-resolved fluorescence spectroscopy (TRFS) and fluorescence lifetime imaging (FLIM) instrumentation and associated methodologies which allow in vivo char...

journal_title：Annals of biomedical engineering

authors： Marcu L

更新日期：2012-02-01 00:00:00

abstract：:Much effort is expended in developing biomimetic scaffolds that provide the micro-architecture of native tissue with appropriate cellular niches. Such scaffolds are often seeded with progenitor cells to generate engineered replacements for diseased or damaged tissues. An alternative approach relies on biology, rather ...

journal_title：Annals of biomedical engineering

authors： Evans CH

更新日期：2015-03-01 00:00:00

abstract：:Defibrillation efficacy testing is a common procedure at defibrillator implantation, with the objective to ensure that each patient receives a system with adequate shock efficacy. In this study, defibrillation shock efficacy as a function of shock energy was modeled by a dose response relationship. The frequency distr...

journal_title：Annals of biomedical engineering

authors： Smits K,Virag N

更新日期：2010-04-01 00:00:00

abstract：:Icariin (Ic) has been demonstrated as a potent osteoinductive compound for bone tissue engineering. However, toxic side effects of the drug and poor biocompatibility of drug delivery systems (DDSs) still limit its application for bone repair in the clinic. To overcome these disadvantages and utilize the osteoinductivi...

journal_title：Annals of biomedical engineering

authors： Li M,Zhang C,Zhong Y,Zhao J

更新日期：2017-11-01 00:00:00

abstract：:A limitation of current tissue engineering vascular graft technology is the provision of an expandable, autologous cell source. By harnessing the multipotency of mesenchymal stem cells (MSC), it is hoped that functional vascular cells can be produced. To date, a range of 2D and 3D environments have been investigated f...

journal_title：Annals of biomedical engineering

authors： O'Cearbhaill ED,Murphy M,Barry F,McHugh PE,Barron V

更新日期：2010-03-01 00:00:00

abstract：:Adherence of a biological graft to the wound surface is the most important factor influencing the ultimate success of graft viability. A machine has been developed to test the adherence of biological graft materials to a substrate such as a wound surface. The peeling mode, which yields reproducible quantitative measur...

journal_title：Annals of biomedical engineering

authors： Dong C,Mead E,Skalak R,Fung YC,Debes JC,Zapata-Sirvent RL,Andree C,Greenleaf G,Cooper M,Hansbrough JF

更新日期：1993-01-01 00:00:00

abstract：:Currently, there are no clinically available tools or applications which could predict osteoarthritis development. Some computational models have been presented to simulate cartilage degeneration, but they are not clinically feasible due to time required to build subject-specific knee models. Therefore, the objective ...

journal_title：Annals of biomedical engineering

authors： Mononen ME,Liukkonen MK,Korhonen RK

更新日期：2019-03-01 00:00:00

abstract：:The objective of this study was to develop a ferrocene mediated glucose biosensor for reverse iontophoresis. An amperometric ferrocene mediated glucose biosensor based on a three electrodes planar configuration was constructed using screen printing technique. Different combinations of glucose oxidase and ferrocene loa...

journal_title：Annals of biomedical engineering

authors： Ching CT,Sun TP,Huang SH,Shieh HL,Chen CY

更新日期：2010-04-01 00:00:00

abstract：:Observing microscopic specimens is often useful in studies of cellular interaction with a vascular wall. We have developed an in vitro side-view flow chamber that permits observations from the side of the cell's contact with various adhesive surfaces under dynamic flow conditions. This side-view flow chamber consists ...

journal_title：Annals of biomedical engineering

authors： Cao J,Usami S,Dong C

更新日期：1997-05-01 00:00:00

abstract：:High density particle image velocimetry, with spatial resolution of O(1 mm), was used to measure the effect of occluder rebound on the flow field near a Bjork-Shiley Monostrut tilting-disk mitral valve. The ability to measure two velocity components over an entire plane simultaneously provides a very different insight...

journal_title：Annals of biomedical engineering

authors： Kini V,Bachmann C,Fontaine A,Deutsch S,Tarbell JM

更新日期：2000-04-01 00:00:00

abstract：:Skeletal muscles can be injured by their own contractions. Such contraction-induced injury, often accompanied by delayed onset of muscle soreness, is a leading cause of the loss of mobility in the rapidly increasing population of elderly people. Unlike other types of muscle injuries which hurt almost exclusively those...

journal_title：Annals of biomedical engineering

authors： Givli S

更新日期：2015-02-01 00:00:00