A long-memory model of motor learning in the saccadic system: a regime-switching approach.

Abstract:

:Maintenance of movement accuracy relies on motor learning, by which prior errors guide future behavior. One aspect of this learning process involves the accurate generation of predictions of movement outcome. These predictions can, for example, drive anticipatory movements during a predictive-saccade task. Predictive saccades are rapid eye movements made to anticipated future targets based on error information from prior movements. This predictive process exhibits long-memory (fractal) behavior, as suggested by inter-trial fluctuations. Here, we model this learning process using a regime-switching approach, which avoids the computational complexities associated with true long-memory processes. The resulting model demonstrates two fundamental characteristics. First, long-memory behavior can be mimicked by a system possessing no true long-term memory, producing model outputs consistent with human-subjects performance. In contrast, the popular two-state model, which is frequently used in motor learning, cannot replicate these findings. Second, our model suggests that apparent long-term memory arises from the trade-off between correcting for the most recent movement error and maintaining consistent long-term behavior. Thus, the model surprisingly predicts that stronger long-memory behavior correlates to faster learning during adaptation (in which systematic errors drive large behavioral changes); greater apparent long-term memory indicates more effective incorporation of error from the cumulative history across trials.

journal_name

Ann Biomed Eng

authors

Wong AL,Shelhamer M

doi

10.1007/s10439-012-0669-2

subject

Has Abstract

pub_date

2013-08-01 00:00:00

pages

1613-24

issue

8

eissn

0090-6964

issn

1573-9686

journal_volume

41

pub_type

杂志文章
  • Assessment of ventricular contractility during cardiac magnetic resonance imaging examinations using normalized maximal ventricular power.

    abstract::Normalized maximal ventricular power (nPWRmax) is an index of cardiac function which measures the innate blood pumping ability, or contractility, of the left ventricle (LV), and its noninvasive assessment could prove useful in a variety of patients. nPWRmax is defined as the maximum instantaneous product of LV pressur...

    journal_title:Annals of biomedical engineering

    pub_type: 临床试验,杂志文章

    doi:10.1114/1.1415530

    authors: Setser RM,Sayre K,Flacke S,Chia J,Lunn K,Lorenz CH

    更新日期:2001-11-01 00:00:00

  • Particle motion within in vitro models of stenosed internal carotid and left anterior descending coronary arteries.

    abstract::Asymmetric 75% and 95% area reduction, transparent Sylgard stenotic models were operated under internal carotid artery (ICA) [Womersley parameter, alpha=5.36, Re(mean) =213 and 180, respectively, and Re(peak)=734 and 410, respectively] and left anterior descending coronary artery (LAD) flow wave forms (alpha=2.65, Re(...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.131

    authors: Cao J,Rittgers SE

    更新日期:1998-03-01 00:00:00

  • Mechanical Performance of Two Left Atrial Appendage Occlusion Systems: In Vitro Comparison of Tug Force, Radial Force, Sealing and Deformation.

    abstract::The aim of this study was to establish in vitro bench-tests of left atrial appendage occlusion (LAAo) devices regarding tug force, radial force and sealing capacity. Two LAAo devices, namely the WATCHMAN™ and the Occlutech®, of three different sizes underwent testing in novel dedicated in vitro setups. Radial force wa...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-018-2057-z

    authors: Menne MF,Schrickel JW,Nickenig G,Al-Kassou B,Nelles D,Schmitz-Rode T,Steinseifer U,Sedaghat A

    更新日期:2018-09-01 00:00:00

  • A preliminary physiologically based pharmacokinetic model for naphthalene and naphthalene oxide in mice and rats.

    abstract::Naphthalene is a toxicant with unusual species and tissue specificity that has been the subject of in vitro studies. We describe a preliminary physiologically based pharmacokinetic (PBPK) model for naphthalene constructed solely from in vitro data for comparison to animal data without the use of adjustable parameters....

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02667357

    authors: Sweeney LM,Shuler ML,Quick DJ,Babish JG

    更新日期:1996-03-01 00:00:00

  • The tendon injury response is influenced by decorin and biglycan.

    abstract::Defining the constituent regulatory molecules in tendon is critical to understanding the process of tendon repair and instructive to the development of novel treatment modalities. The purpose of this study is to define the structural, expressional, and mechanical changes in the tendon injury response, and elucidate th...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-013-0915-2

    authors: Dunkman AA,Buckley MR,Mienaltowski MJ,Adams SM,Thomas SJ,Satchell L,Kumar A,Pathmanathan L,Beason DP,Iozzo RV,Birk DE,Soslowsky LJ

    更新日期:2014-03-01 00:00:00

  • Mitral Valve Regurgitation with a Rotary Left Ventricular Assist Device: The Haemodynamic Effect of Inlet Cannulation Site and Speed Modulation.

    abstract::Mitral valve regurgitation (MVR) is common in patients receiving left ventricular assist device (LVAD) support, however the haemodynamic effect of MVR is not entirely clear. This study evaluated the haemodynamic effect of MVR with LVAD support and the influence of inflow cannulation site and LVAD speed modulation. Lef...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-016-1579-5

    authors: Gregory SD,Stevens MC,Wu EL,Pauls JP,Kleinheyer M,Fraser JF

    更新日期:2016-09-01 00:00:00

  • Stress relaxation preconditioning of porcine aortic valves.

    abstract::In uniaxial tensile testing, load preconditioning is used to generate repeatable load/elongation curves and set a "reference state" for subsequent tensile tests. We have observed however, that for porcine aortic valve (PAV) tissues, preconditioning does not lead to repeatable stress relaxation curves. We thus investig...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1023/b:abme.0000019176.49650.19

    authors: Carew EO,Garg A,Barber JE,Vesely I

    更新日期:2004-04-01 00:00:00

  • Potential of the genetic algorithm neural network in the assessment of gait patterns in ankle arthrodesis.

    abstract::The aim of this study was to develop an empirical model of parameter-based gait data, based on an artificial neural network and a genetic algorithm, for the assessment of patients after ankle arthrodesis. Ground reaction force vectors were measured by force platforms during level walking. Nine force parameters express...

    journal_title:Annals of biomedical engineering

    pub_type: 临床试验,杂志文章

    doi:10.1114/1.1342053

    authors: Wu WL,Su FC,Cheng YM,Chou YL

    更新日期:2001-01-01 00:00:00

  • Cue-Signal-Response Analysis in 3D Chondrocyte Scaffolds with Anabolic Stimuli.

    abstract::Articular cartilage is an avascular connective tissue responsible for bearing loads. Cell signaling plays a central role in cartilage homeostasis and tissue engineering by directing chondrocytes to synthesize/degrade the extracellular matrix or promote inflammatory responses. The aim of this paper was to investigate a...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-017-1964-8

    authors: Neidlin M,Korcari A,Macheras G,Alexopoulos LG

    更新日期:2018-02-01 00:00:00

  • An experimental evaluation of the use of an ensemble average for the calculation of turbulence in pulsatile flow.

    abstract::A comparison was made between turbulence calculated by subtracting an ensemble average from the instantaneous velocity and calculations made with a high pass digital filter. Velocity was measured with a laser Doppler anemometer in vitro in the region of a normal porcine aortic valve and in patients with a hot film ane...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02584215

    authors: Walburn FJ,Sabbah HN,Stein PD

    更新日期:1983-01-01 00:00:00

  • Linear homeomorphic models for muscles in the head-neck region.

    abstract::The linear homeomorphic muscle model proposed by Enderle and coworkers for the rectus eye muscle is fitted to reflect the dynamics of muscles in the head-neck complex, specifically in muscles involved in gaze shifts. This parameterization of the model for different muscles in the neck region will serve to drive a 3D d...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-009-9851-6

    authors: Sierra DA,Enderle JD

    更新日期:2010-02-01 00:00:00

  • Blood pressure measurement in noise intensive environments using adaptive interference cancellation.

    abstract::The traditional auscultatory technique and current methodologies for measuring human blood pressure are limited when used in situations where extreme vibration or acoustic noise is present. In this study, human subjects were used to establish the effectiveness of a novel adaptive blood pressure monitoring (ABPM) syste...

    journal_title:Annals of biomedical engineering

    pub_type: 临床试验,杂志文章

    doi:10.1114/1.1481051

    authors: Pinto L,Dhanantwari A,Wong W,Stergiopoulos S,Maris M

    更新日期:2002-05-01 00:00:00

  • Dynamics of revolution time variability in cycling pattern: voluntary intent can alter the long-range autocorrelations.

    abstract::Long-range dependency has been found in most rhythmic motor signals. The origin of this property is unknown and largely debated. There is a controversy on the influence of voluntary control induced by requiring a pre-determined pace such as asking subjects to step to a metronome. We studied the cycle duration variabil...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10439-013-0834-2

    authors: Warlop TB,Bollens B,Crevecoeur F,Detrembleur C,Lejeune TM

    更新日期:2013-08-01 00:00:00

  • Theoretical study of the effects of vascular smooth muscle contraction on strain and stress distributions in arteries.

    abstract::To study the effects of smooth muscle contraction and relaxation on the strain and stress distribution in the vascular wall, a mathematical model was proposed. The artery was assumed to be a thick-walled orthotropic tube made of nonlinear, incompressible elastic material. Considering that the contraction of smooth mus...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.191

    authors: Rachev A,Hayashi K

    更新日期:1999-07-01 00:00:00

  • Sensitivity of indentation testing to step-off edges and interface integrity in cartilage repair.

    abstract::Step-off edges and tissue interfaces are prevalent in cartilage injury such as after intra-articular fracture and reduction, and in focal defects and surgical repair procedures such as osteochondral graft implantation. It would be useful to assess the function of injured or donor tissues near such step-off edges and t...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1023/b:abme.0000017553.01798.12

    authors: Bae WC,Law AW,Amiel D,Sah RL

    更新日期:2004-03-01 00:00:00

  • Evaluation of three animal models for concussion and serious brain injury.

    abstract::Three animal models were evaluated in this study involving head impacts of the rat, including the Marmarou drop-weight and two momentum-exchange techniques. In series 1, 36 Wistar rats were hit on the side of the free-moving head using Marmarou's 450 g impact mass at 4.4, 5.4, and 6.3 m/s. Head acceleration was measur...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-011-0386-2

    authors: Viano DC,Hamberger A,Bolouri H,Säljö A

    更新日期:2012-01-01 00:00:00

  • Carbachol-induced volume adaptation in mouse bladder and length adaptation via rhythmic contraction in rabbit detrusor.

    abstract::The length-tension (L-T) relationships in rabbit detrusor smooth muscle (DSM) are similar to those in vascular and airway smooth muscles and exhibit short-term length adaptation characterized by L-T curves that shift along the length axis as a function of activation and strain history. In contrast to skeletal muscle, ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-012-0590-8

    authors: Speich JE,Wilson CW,Almasri AM,Southern JB,Klausner AP,Ratz PH

    更新日期:2012-10-01 00:00:00

  • Rat aortic smooth muscle cells contract in response to serum and its components in a calcium independent manner.

    abstract::Diluted serum provides a model of interstitial fluid that can be used to study the response of smooth muscle cells (SMCs) to interstitial flow. The effect of serum and some of its components on SMC contraction (area reduction) and intracellular calcium ([Ca2+]i) response were characterized in rat aortic SMC in vitro. ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-004-7820-7

    authors: Ainslie K,Shi ZD,Garanich JS,Tarbell JM

    更新日期:2004-12-01 00:00:00

  • Degradation, bioactivity, and osteogenic potential of composites made of PLGA and two different sol-gel bioactive glasses.

    abstract::We have developed poly(L: -lactide-co-glycolide) (PLGA) based composites using sol-gel derived bioactive glasses (S-BG), previously described by our group, as composite components. Two different composite types were manufactured that contained either S2-high content silica S-BG, or A2-high content lime S-BG. The compo...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-011-0307-4

    authors: Pamula E,Kokoszka J,Cholewa-Kowalska K,Laczka M,Kantor L,Niedzwiedzki L,Reilly GC,Filipowska J,Madej W,Kolodziejczyk M,Tylko G,Osyczka AM

    更新日期:2011-08-01 00:00:00

  • Analytical Modelling of Natural Frequency of Tympanic Membrane as the Low-Frequency Limit of Hearing.

    abstract::We examine the low-frequency limit of hearing of the mammalian ear through the analytical modelling of the natural frequency of the tympanic membrane. The resulting equation of the natural frequency of the modelled tympanic membrane is numerically verified against previous theoretical studies, and is statistically val...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-019-02356-4

    authors: Jabaraj DJ

    更新日期:2020-01-01 00:00:00

  • Evaluation of effectiveness of a facet wiring technique: an in vitro biomechanical investigation.

    abstract::The effects of facet wiring procedure commonly used for stabilizing cervical spines after laminectomy or bilateral facet dislocation on the motion behavior of whole cervical spines are investigated using a Selspot II system. A fresh human ligamentous intact specimen was potted at T1/T2 vertebra and clinically relevant...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02368022

    authors: Goel VK,Clark CR,Harris KG,Kim YE,Schulte KR

    更新日期:1989-01-01 00:00:00

  • Automatic Detection of Contracting Muscle Regions via the Deformation Field of Transverse Ultrasound Images: A Feasibility Study.

    abstract::Accurate identification of contracting muscles can help us to understand the muscle function in both physiological and pathological conditions. Conventional electromyography (EMG) have limited access to deep muscles, crosstalk, or instability in the recordings. Accordingly, a novel framework was developed to detect co...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-020-02557-2

    authors: Zheng Y,Shin H,Kamper DG,Hu X

    更新日期:2021-01-01 00:00:00

  • Modeling soluble gas exchange in the airways and alveoli.

    abstract::A mathematical model of heat, water and soluble gas exchange in the airways and alveoli was used to predict the location of soluble gas exchange in the lung. A previously published model of heat, water and soluble gas exchange in the airways was improved by incorporating anatomical data on the airway wall to better de...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.1630600

    authors: Anderson JC,Babb AL,Hlastala MP

    更新日期:2003-12-01 00:00:00

  • The effects of anisotropy on the stress analyses of patient-specific abdominal aortic aneurysms.

    abstract::The local dilation of the infrarenal abdominal aorta, termed an abdominal aortic aneurysm (AAA), is often times asymptomatic and may eventually result in rupture-an event associated with a significant mortality rate. The estimation of in-vivo stresses within AAAs has been proposed as a useful tool to predict the likel...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-008-9490-3

    authors: Vande Geest JP,Schmidt DE,Sacks MS,Vorp DA

    更新日期:2008-06-01 00:00:00

  • Multifunctional FePt nanoparticles for radiation-guided targeting and imaging of cancer.

    abstract::A multifunctional FePt nanoparticle was developed that targets tumor microvasculature via "radiation-guided" peptides, and is detected by both near-infrared (NIR) fluorescence imaging and analytical mass spectrometry methods. Tumor specific binding was first measured by biotinylated peptide linked to fluorophore-conju...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-010-0219-8

    authors: Hariri G,Wellons MS,Morris WH 3rd,Lukehart CM,Hallahan DE

    更新日期:2011-03-01 00:00:00

  • The current status and future directions of impedance cardiography in ICU.

    abstract::Impedance cardiography has not achieved popularity in the Intensive Care Unit (ICU) to date probably because of the limitations in technique and interpretation associated with the altered physiology of critically ill patients, and also because of interference from other machinery in the ICU. The current climate of que...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02368068

    authors: Fuller H,Raskob G,ter Keurs H,Hull R

    更新日期:1989-01-01 00:00:00

  • The Application of Digital Volume Correlation (DVC) to Evaluate Strain Predictions Generated by Finite Element Models of the Osteoarthritic Humeral Head.

    abstract::Continuum-level finite element models (FEMs) of the humerus offer the ability to evaluate joint replacement designs preclinically; however, experimental validation of these models is critical to ensure accuracy. The objective of the current study was to quantify experimental full-field strain magnitudes within osteoar...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-020-02549-2

    authors: Kusins J,Knowles N,Columbus M,Oliviero S,Dall'Ara E,Athwal GS,Ferreira LM

    更新日期:2020-12-01 00:00:00

  • A computational study of the effect of false vocal folds on glottal flow and vocal fold vibration during phonation.

    abstract::The false vocal folds are believed to be components of the acoustic filter that is responsible for shaping the voice. However, the effects of false vocal folds on the vocal fold vibration and the glottal aerodynamic during phonation remain unclear. This effect has implications for computational modeling of phonation a...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-008-9630-9

    authors: Zheng X,Bielamowicz S,Luo H,Mittal R

    更新日期:2009-03-01 00:00:00

  • Developments and Control of Biocompatible Conducting Polymer for Intracorporeal Continuum Robots.

    abstract::Dexterity of robots is highly required when it comes to integration for medical applications. Major efforts have been conducted to increase the dexterity at the distal parts of medical robots. This paper reports on developments toward integrating biocompatible conducting polymers (CP) into inherently dexterous concent...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-018-2038-2

    authors: Chikhaoui MT,Benouhiba A,Rougeot P,Rabenorosoa K,Ouisse M,Andreff N

    更新日期:2018-10-01 00:00:00

  • Gaussian pulse decomposition: an intuitive model of electrocardiogram waveforms.

    abstract::This study presents a novel approach to modeling the electrocardiogram (ECG): the Gaussian pulse decomposition. Constituent waves of the ECG are decomposed into and represented by Gaussian pulses using an iterative algorithm: the chip away decomposition (ChAD) algorithm. At each iteration, a nonlinear minimization met...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02648039

    authors: Suppappola S,Sun Y,Chiaramida SA

    更新日期:1997-03-01 00:00:00