High fidelity virtual stenting (HiFiVS) for intracranial aneurysm flow diversion: in vitro and in silico.

abstract：:This study evaluates the use of artificial neural networks to estimate stroke volume from pre-processed, thoracic impedance plethysmograph signals from 20 healthy subjects. Standard back-propagation was used to train the networks, with Doppler stroke volume estimates as the desired output. The trained networks were th...

journal_title：Annals of biomedical engineering

authors： Mulavara AP,Timmons WD,Nair MS,Gupta V,Kumar AA,Taylor BC

更新日期：1998-07-01 00:00:00

abstract：:Cardiac MRI (CMR) techniques offer non-invasive visualizations of cardiac morphology and function. However, imaging can be time-consuming and complex. Seismocardiography (SCG) measures physical vibrations transmitted through the chest from the beating heart and pulsatile blood flow. SCG signals can be acquired quickly...

journal_title：Annals of biomedical engineering

authors： Johnson EMI,Heller JA,Garcia Vicente F,Sarnari R,Gordon D,McCarthy PM,Barker AJ,Etemadi M,Markl M

更新日期：2020-06-01 00:00:00

abstract：:Despite cellular environments having dynamic characteristics, many laboratories utilized static polyacrylamide hydrogels to study the ECM-cell relationship. To attain a more in vivo like environment, we have developed a dynamic, DNA-crosslinked hydrogel (DNA gel). Through the controlled delivery of DNA, we can tempora...

journal_title：Annals of biomedical engineering

authors： Previtera ML,Trout KL,Verma D,Chippada U,Schloss RS,Langrana NA

更新日期：2012-05-01 00:00:00

abstract：:In this work, we propose an analog electrical model of the coronary circulation for patients with obstructive disease undergoing revascularization. In this clinical situation, the collateral circulation to the occluded artery is difficult to ascertain via preoperative measurements and well-developed collaterals might ...

journal_title：Annals of biomedical engineering

authors： Maasrani M,Verhoye JP,Corbineau H,Drochon A

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:This work explores for the first time the effects of temperature increments on the development of high shear stresses between plaque and arterial wall due to their different dilatational properties. Data from the literature report febrile reactions prior to myocardial infarction in patients with normal coron...

journal_title：Annals of biomedical engineering

authors： Guinea GV,Atienza JM,Fantidis P,Rojo FJ,Ortega A,Torres M,Gonzalez P,Elices ML,Hayashi K,Elices M

更新日期：2008-01-01 00:00:00

abstract：:A mathematical model is presented that estimates joint kinematics and kinetics using measured external resultant loads and readily available parameters. The musculo-skeletal system was represented by a planar three degrees of freedom open kinematic chain. Information extraction was limited to the flexion-extension fun...

journal_title：Annals of biomedical engineering

authors： Mazzà C,Cappozzo A

更新日期：2004-05-01 00:00:00

abstract：:It is well known that neutrophils take much longer to traverse the pulmonary capillary bed than erythrocytes, and this is likely due to differences in the structure and rheology of the cells. In this study, we simulate the transit of a neutrophil in a capillary using a Newtonian drop model and a viscoelastic drop mode...

journal_title：Annals of biomedical engineering

authors： Zhou C,Yue P,Feng JJ

更新日期：2007-05-01 00:00:00

abstract：:Potential human and environmental hazards resulting from the exposure of living organisms to silver nanoparticles (Ag NPs) have been the subject of intensive discussion in the last decade. Despite the growing use of Ag NPs in biomedical applications, a quantification of the toxic effects as a function of the total sil...

journal_title：Annals of biomedical engineering

authors： Poli D,Mattei G,Ucciferri N,Ahluwalia A

更新日期：2020-04-01 00:00:00

abstract：:We have developed a method for quantifying the complexity of activation patterns observed during ventricular fibrillation (VF) that is based on our previously reported methodology for decomposing epicardial mapping data into a set of isolated wavefronts. One-half second datasets are acquired from a 21 x 24 array of un...

journal_title：Annals of biomedical engineering

authors： Rogers JM,Usui M,KenKnight BH,Ideker RE,Smith WM

更新日期：1997-09-01 00:00:00

abstract：:Glaucoma is a common optic neuropathy characterized by retinal ganglion cell death. Elevated intraocular pressure (IOP), a key risk factor for glaucoma, leads to significant biomechanical deformation of optic nerve head (ONH) cells and tissues. ONH astrocytes respond to this deformation by transforming to a reactive, ...

journal_title：Annals of biomedical engineering

authors： Mulvihill JJE,Raykin J,Snider EJ,Schildmeyer LA,Zaman I,Platt MO,Kelly DJ,Ethier CR

更新日期：2018-02-01 00:00:00

abstract：:The left-right asymmetry in the potential amplitude on the scalp was studied in poststroke patients by using flash visual evoked potential (VEP) and a numerical two-dimensional model of the head. The left-right asymmetry of the VEP was measured in three patients after thrombosis, in one after hemorrhage, and in one he...

journal_title：Annals of biomedical engineering

authors： Abboud S,Bar L,Rosenfeld M,Ring H,Glass I

更新日期：1996-01-01 00:00:00

abstract：:A python computer package is developed to segment and analyze scanning electron microscope (SEM) images of scaffolds for bone tissue engineering. The method requires only a portion of an SEM image to be labeled and used for training. The algorithm is then able to detect the pore characteristics for other SEM images ac...

journal_title：Annals of biomedical engineering

authors： Rouhollahi A,Ilegbusi O,Foroosh H

更新日期：2020-10-15 00:00:00

abstract：:Mechanical ventilation is a life-support therapy for intensive care patients suffering from respiratory failure. To reduce the current rate of ventilator-induced lung injury requires ventilator settings that are patient-, time-, and disease-specific. A common lung protective strategy is to optimise the level of positi...

journal_title：Annals of biomedical engineering

authors： Morton SE,Knopp JL,Chase JG,Möller K,Docherty P,Shaw GM,Tawhai M

更新日期：2019-07-01 00:00:00

abstract：:Hemodynamic forces are known to be able to induce an inflammatory phenotype in endothelial cells (ECs). The EC glycocalyx (GCX) is a dynamic structure which is regulated in response to different stimuli and hypothesized as an important contributor to the mechanotransduction of wall shear stresses (WSS). In this work, ...

journal_title：Annals of biomedical engineering

authors： Cooper S,McDonald K,Burkat D,Leask RL

更新日期：2017-09-01 00:00:00

abstract：:While considerable efforts have been expended to develop snore-driven markers for detecting obstructive sleep apnea (OSA), there is little emphasis on the relationship between the human upper airway (UA) dimensions and the attributes of snores. This paper aims to investigate the acoustical and perceptual impacts of ch...

journal_title：Annals of biomedical engineering

authors： Ng AK,Koh TS,Baey E,Puvanendran K

更新日期：2009-09-01 00:00:00

abstract：:This experimental work focused on the sensor selection for the development of a needle-like instrument to treat small isolated cartilage defects with hydrogels. The aim was to identify the most accurate and sensitive imaging method to determine the location and size of defects compared to a gold standard (µCT). Only i...

journal_title：Annals of biomedical engineering

authors： Horeman T,Buiter EC,Pouran B,Stijntjes M,Dankelman J,Tuijthof GJM

更新日期：2018-11-01 00:00:00

abstract：:Intramuscular pressure (IMP), defined as skeletal muscle interstitial fluid pressure, reflects changes in individual muscle tension and may provide crucial insight into musculoskeletal biomechanics and pathologies. IMP may be measured using fiber-optic fluid pressure sensors, provided the sensor is adequately anchored...

journal_title：Annals of biomedical engineering

authors： Go SA,Jensen ER,O'Connor SM,Evertz LQ,Morrow DA,Ward SR,Lieber RL,Kaufman KR

更新日期：2017-03-01 00:00:00

abstract：:Extraction of the cardiac surfaces of interest from multi-detector computed tomographic (MDCT) data is a pre-requisite step for cardiac analysis, as well as for image guidance procedures. Most of the existing methods need manual corrections, which is time-consuming. We present a fully automatic segmentation technique ...

journal_title：Annals of biomedical engineering

authors： Antunes S,Esposito A,Palmisano A,Colantoni C,Cerutti S,Rizzo G

更新日期：2016-05-01 00:00:00

abstract：:This study aimed to quantify the elongation patterns of the collateral ligaments following TKA during functional activities of daily living. Using mobile video-fluoroscopy to capture radiographic images of the knee in a group of six patients, each with an ultra-congruent knee implant, tibiofemoral kinematics were reco...

journal_title：Annals of biomedical engineering

authors： Hosseini Nasab SH,Smith CR,Schütz P,Damm P,Trepczynski A,List R,Taylor WR

更新日期：2020-04-01 00:00:00

abstract：:Normal physiological mechanical forces cause constant tissue renewal in aortic valve leaflets (AVL) while altered mechanical forces incite changes in their structural and biological properties. The current study aims at characterizing the remodeling properties of AVL subjected to cyclic circumferential stretch in a st...

journal_title：Annals of biomedical engineering

authors： Balachandran K,Konduri S,Sucosky P,Jo H,Yoganathan AP

更新日期：2006-11-01 00:00:00

abstract：:In this study various blood rheological assumptions are numerically investigated for the hemodynamic properties of intra-stent flow. Non-newtonian blood properties have never been implemented in blood coronary stented flow investigation, although its effects appear essential for a correct estimation and distribution o...

journal_title：Annals of biomedical engineering

authors： Benard N,Perrault R,Coisne D

更新日期：2006-08-01 00:00:00

abstract：:A model predictive control strategy to simultaneously regulate hemodynamic and anesthetic variables in critical care patients is presented. A nonlinear canine circulatory model, which has been used to study the effect of inotropic and vasoactive drugs on hemodynamic variables, has been extended to include propofol pha...

journal_title：Annals of biomedical engineering

authors： Rao RR,Bequette BW,Roy RJ

更新日期：2000-01-01 00:00:00

abstract：:It is widely recognized that the bacteria sequestered in a biofilm on a medical implant are much more resistant to antibiotics than their planktonic counterparts. Recent studies have shown that application of antibiotic along with low power ultrasound significantly increases the killing of planktonic bacteria by the a...

journal_title：Annals of biomedical engineering

authors： Qian Z,Sagers RD,Pitt WG

更新日期：1997-01-01 00:00:00

abstract：:We describe a model for the Compound Action Currents (CACs) and Compound Action Potentials (CAPs) produced by a peripheral nerve bundle in vitro. The Single Fiber Action Currents (SFACs) and the extracellular Single Fiber Action Potentials (SFAPs) are calculated using a generalized volume conduction model. Frequency-d...

journal_title：Annals of biomedical engineering

authors： Wijesinghe RS,Gielen FL,Wikswo JP Jr

更新日期：1991-01-01 00:00:00

abstract：:For an optimal guidance of the rehabilitation therapy of stroke patients in an in-home setting, objective, and patient-specific performance assessment of arm movements is needed. In this study, metrics of hand movement relative to the pelvis and the sternum were estimated in 13 stroke subjects using a full body ambula...

journal_title：Annals of biomedical engineering

authors： van Meulen FB,Reenalda J,Buurke JH,Veltink PH

更新日期：2015-02-01 00:00:00

abstract：:Despite the use of helmets in American football, brain injuries are still prevalent. To reduce the burden of these injuries, novel impact mitigation systems are needed. The Vicis Zero1 (VZ1) American football helmet is unique in its use of multi-directional buckling structures sandwiched between a deformable outer she...

journal_title：Annals of biomedical engineering

authors： Giudice JS,Caudillo A,Mukherjee S,Kong K,Park G,Kent R,Panzer MB

更新日期：2020-05-01 00:00:00

abstract：:Correct development of neuronal tracts requires the coordination of multiple permissive and inhibitory signals. By generating an in vitro microenvironment using soft lithography and microfluidic techniques, multiple guidance cues can be presented in a spatially defined way. Here we evaluated how neurites of dorsal roo...

journal_title：Annals of biomedical engineering

authors： Li GN,Liu J,Hoffman-Kim D

更新日期：2008-06-01 00:00:00

abstract：:Dendritic cells (DCs) are crucial components of the immune response, strategically positioned as immune sentinels. Complex trafficking and accurate positioning of DCs are indispensable for both immunity and tolerance. This is particularly evident for their therapeutic application where an unmet clinical need exists fo...

journal_title：Annals of biomedical engineering

authors： Silva Z,Konstantopoulos K,Videira PA

更新日期：2012-04-01 00:00:00

abstract：:3D bioprinting technology is a promising approach for corneal stromal tissue regeneration. In this study, gelatin methacrylate (GelMA) mixed with corneal stromal cells was used as a bioink. The visible light-based stereolithography (SLA) 3D bioprinting method was utilized to print the anatomically similar dome-shaped ...

journal_title：Annals of biomedical engineering

authors： Mahdavi SS,Abdekhodaie MJ,Kumar H,Mashayekhan S,Baradaran-Rafii A,Kim K

更新日期：2020-07-01 00:00:00

abstract：:Organ models are used for planning and simulation of operations, developing new surgical instruments, and training purposes. There is a substantial demand for in vitro organ phantoms, especially in urological surgery. Animal models and existing simulator systems poorly mimic the detailed morphology and the physical pr...

journal_title：Annals of biomedical engineering

authors： Adams F,Qiu T,Mark A,Fritz B,Kramer L,Schlager D,Wetterauer U,Miernik A,Fischer P

更新日期：2017-04-01 00:00:00