Design Considerations of a Fiber Optic Pressure Sensor Protective Housing for Intramuscular Pressure Measurements.

abstract：:Femoral neck fractures are a relevant clinical and social problem. The aim of this study was to improve the prediction of patients at-risk of femoral neck fracture with respect to the current densitometric-based methods. In particular, finite element models were used to assess the prediction accuracy obtained by combi...

journal_title：Annals of biomedical engineering

authors： Testi D,Viceconti M,Cappello A,Gnudi S

更新日期：2002-06-01 00:00:00

abstract：:Recent advances in fluorescence confocal endomicroscopy have allowed real-time identification of residual tumour cells on the walls of the cavity left by breast conserving surgery. However, it is difficult to systematically survey the surgical site because of the small imaging field-of-view of these probes, compounded...

journal_title：Annals of biomedical engineering

authors： Zuo S,Hughes M,Yang GZ

更新日期：2016-07-01 00:00:00

abstract：:Pressure ulcers (PUs) can occur in any situations where people are subjected to non-uniform distribution of pressure over a prolonged period. They can have devastating effects on the patients' well-being and in extreme conditions can prove fatal. In addition to traditional wisdom implicating mechanically induced ischa...

journal_title：Annals of biomedical engineering

authors： Mirtaheri P,Gjøvaag T,Worsley PR,Bader DL

更新日期：2015-02-01 00:00:00

abstract：:The identification of the insulin minimal model (MM) for the estimation of insulin secretion rate (ISR) and physiological indexes (e.g. beta-cell sensitivity) requires the knowledge of C-peptide (CP) kinetics. The four parameters of the two-compartment model of CP kinetics in a given individual can be derived either f...

journal_title：Annals of biomedical engineering

authors： Magni P,Sparacino G,Bellazzi R,Toffolo GM,Cobelli C

更新日期：2004-07-01 00:00:00

abstract：:Numerical models of the mitral valve have been used to elucidate mitral valve function and mechanics. These models have evolved from simple two-dimensional approximations to complex three-dimensional fully coupled fluid structure interaction models. However, to date these models lack direct one-to-one experimental val...

journal_title：Annals of biomedical engineering

authors： Rabbah JP,Saikrishnan N,Yoganathan AP

更新日期：2013-02-01 00:00:00

abstract：:A role for mechanical stimulation in the control of cell fate has been proposed and mechanical conditioning of mesenchymal stem cells (MSCs) is of interest in directing MSC behavior for tissue engineering applications. This study investigates strain-induced differentiation and proliferation of MSCs, and investigates t...

journal_title：Annals of biomedical engineering

authors： Kearney EM,Farrell E,Prendergast PJ,Campbell VA

更新日期：2010-05-01 00:00:00

abstract：:During the fetal-to-neonatal transition, transvalvular pressures (TVPs) on the aortic and pulmonary valves change dramatically-but differently for each valve. We have examined changes in the molecular stability and crosslinking of collagen during this transition. Aortic and pulmonary valves were harvested from fetal a...

journal_title：Annals of biomedical engineering

authors： Aldous IG,Lee JM,Wells SM

更新日期：2010-09-01 00:00:00

abstract：:Recent evidence suggests that energy substrate metabolism forms the link between gene expression and contractile function of the heart. This hypothesis draws on three seemingly unconnected observations, made in 1941 by three different investigators. The first gave rise to the concept of the dynamic nature of body cons...

journal_title：Annals of biomedical engineering

authors： Taegtmeyer H

更新日期：2000-08-01 00:00:00

abstract：:The objective of this study was to develop a ferrocene mediated glucose biosensor for reverse iontophoresis. An amperometric ferrocene mediated glucose biosensor based on a three electrodes planar configuration was constructed using screen printing technique. Different combinations of glucose oxidase and ferrocene loa...

journal_title：Annals of biomedical engineering

authors： Ching CT,Sun TP,Huang SH,Shieh HL,Chen CY

更新日期：2010-04-01 00:00:00

abstract：:Parameters of physiological models are commonly associated in an input-output experiment with a specific pattern of the system response. This association is often made on an intuitive basis by traditional sensitivity analysis, i.e., by inspecting the variations of model output trajectories with respect to parameter va...

journal_title：Annals of biomedical engineering

authors： Thomaseth K,Cobelli C

更新日期：1999-09-01 00:00:00

abstract：:This paper reviews the applications of accelerometers on the detection of physiological acoustic signals such as heart sounds, respiratory sounds, and gastrointestinal sounds. These acoustic signals contain a rich reservoir of vital physiological and pathological information. Accelerometer-based systems enable continu...

journal_title：Annals of biomedical engineering

authors： Hu Y,Kim EG,Cao G,Liu S,Xu Y

更新日期：2014-11-01 00:00:00

abstract：:The multiphoton fluorescence recovery after photobleaching (MP-FRAP) technique has been developed to measure the three-dimensional (3D) solute diffusion within biological systems. However, current 3D MP-FRAP models are based on isotropic diffusion and spatial domain analysis. The 3D anisotropic diffusion and frequency...

journal_title：Annals of biomedical engineering

authors： Shi C,Cisewski SE,Bell PD,Yao H

更新日期：2014-03-01 00:00:00

abstract：:Linear autoregressive (AR) model-based heart rate (HR) spectral analysis has been widely used to study HR dynamics. Owing to system and measurement noise, the parameters of an AR model have intrinsic statistical uncertainty. In this study, we evaluate how this AR parameter uncertainty can translate to uncertainty in H...

journal_title：Annals of biomedical engineering

authors： Christini DJ,Kulkarni A,Rao S,Stutman ER,Bennett FM,Hausdorff JM,Oriol N,Lutchen KR

更新日期：1995-03-01 00:00:00

abstract：:Membrane introduction mass spectrometry has been applied to inert gas measurements in blood and tissue, but gases with low blood solubility are associated with reduced sensitivity. Countercurrent extraction of inert gases from a blood sample into a water carrier phase has the potential to extract most of the gas sampl...

journal_title：Annals of biomedical engineering

authors： Baumgardner JE,Neufeld GR

更新日期：1997-09-01 00:00:00

abstract：:Electromechanical reshaping (EMR) of cartilage provides an alternative to the classic surgical techniques of modifying the shape of facial cartilages. The original embodiment of EMR required surface electrodes to be in direct contact with the entire cartilage region being reshaped. This study evaluates the feasibility...

journal_title：Annals of biomedical engineering

authors： Manuel CT,Foulad A,Protsenko DE,Sepehr A,Wong BJ

更新日期：2010-11-01 00:00:00

abstract：:We propose a mathematical model for analyses of the elastic properties of the wall of the outer hair cell (OHC) in the inner ear. The model reflects the properties of the major components of the OHC wall: the subsurface cisternae, the cortical lattice, the plasma membrane, and the radial pillars. The wall is treated a...

journal_title：Annals of biomedical engineering

authors： Spector AA,Brownell WE,Popel AS

更新日期：1998-01-01 00:00:00

abstract：:A mathematical model has been developed to investigate previously obtained experimental findings relating to the activation of factor X by surface-bound tissue factor--factor VIIa (TF:VIIa) in a tubular flow reactor. In those experiments, factor X was perfused through a microcapillary tube over a range of flow (shear)...

journal_title：Annals of biomedical engineering

authors： Gir S,Slack SM,Turitto VT

更新日期：1996-05-01 00:00:00

abstract：:In recent years, advances in computing power and computational methods have made it possible to perform detailed simulations of the coronary artery stenting procedure and of related virtual tests of performance (including fatigue resistance, corrosion and haemodynamic disturbance). Simultaneously, there has been a gro...

journal_title：Annals of biomedical engineering

authors： Bressloff NW,Ragkousis G,Curzen N

更新日期：2016-02-01 00:00:00

abstract：:The applicability of a computer model, which relates the transmural mechanical distribution in the left ventricle (LV) to its global function at different loading conditions, was evaluated in patients with normal to near normal LV function undergoing cardiac catheterization. Left ventriculography and measurements of a...

journal_title：Annals of biomedical engineering

authors： Abboud L,Beyar R,Battler A,Rat M,Cohen A,Sideman S

更新日期：1990-01-01 00:00:00

abstract：:Upon nerve injury, the body creates an environment consisting of permissive and non-permissive cues that instruct the function of cells involved in nerve repair. Among other roles, the developing extracellular matrix (ECM) acts as an underlying substrate to guide the union of neurites extending from the proximal stump...

journal_title：Annals of biomedical engineering

authors： Man AJ,Leach JK,Bannerman P

更新日期：2014-06-01 00:00:00

abstract：:We propose a multifrequency energy transmission scheme for annular phased arrays in deep-body hyperthermia. The problem of frequency dependent resonance effects reported in hyperthermia phantom calibration studies, leading to skewed energy deposition patterns and unwanted energy maxima (hot spots), is addressed by com...

journal_title：Annals of biomedical engineering

authors： Jacobsen S,Melandsø F

更新日期：2002-01-01 00:00:00

abstract：:Osteoarthritis (OA) is a progressive, degenerative disease of articulating joints that not only affects the elderly, but also involves younger, more active individuals with prolonged participation in high physical-demand activities. Thus, effective therapies that are easy to adopt clinically are critical in limiting t...

journal_title：Annals of biomedical engineering

authors： Holyoak DT,Tian YF,van der Meulen MC,Singh A

更新日期：2016-06-01 00:00:00

abstract：:Despite cellular environments having dynamic characteristics, many laboratories utilized static polyacrylamide hydrogels to study the ECM-cell relationship. To attain a more in vivo like environment, we have developed a dynamic, DNA-crosslinked hydrogel (DNA gel). Through the controlled delivery of DNA, we can tempora...

journal_title：Annals of biomedical engineering

authors： Previtera ML,Trout KL,Verma D,Chippada U,Schloss RS,Langrana NA

更新日期：2012-05-01 00:00:00

abstract：:Impedance data, e.g., system responses, from perturbing small amplitude applied sinusoid signals of near DC to high kilohertz frequencies, give chemical information. Analysis of frequency-dependent imaginary and real impedance proceeds from equivalent analog circuit elements to chemical and physical significance deter...

journal_title：Annals of biomedical engineering

authors： Buck RP

更新日期：1992-01-01 00:00:00

abstract：:A wide range of length and time scales are relevant to pharmacology, especially in drug development, drug design and drug delivery. Therefore, multiscale computational modeling and simulation methods and paradigms that advance the linkage of phenomena occurring at these multiple scales have become increasingly importa...

journal_title：Annals of biomedical engineering

authors： Clancy CE,An G,Cannon WR,Liu Y,May EE,Ortoleva P,Popel AS,Sluka JP,Su J,Vicini P,Zhou X,Eckmann DM

更新日期：2016-09-01 00:00:00

abstract：:Mitral valve regurgitation (MVR) is common in patients receiving left ventricular assist device (LVAD) support, however the haemodynamic effect of MVR is not entirely clear. This study evaluated the haemodynamic effect of MVR with LVAD support and the influence of inflow cannulation site and LVAD speed modulation. Lef...

journal_title：Annals of biomedical engineering

authors： Gregory SD,Stevens MC,Wu EL,Pauls JP,Kleinheyer M,Fraser JF

更新日期：2016-09-01 00:00:00

abstract：:Fingertips wrinkle due to long exposure to water. The biological reason for this morphological change is unclear and still not fully understood. There are two main hypotheses for the underlying mechanism of fingertip wrinkling: the 'shrink' model (in which the wrinkling is driven by the contraction of the lower layers...

journal_title：Annals of biomedical engineering

authors： Sáez P,Zöllner AM

更新日期：2017-04-01 00:00:00

abstract：:We and others have shown that changing surface characteristics of the spacer implanted during the first Masquelet stage alters some aspects of membrane development. Previously we demonstrated that titanium (TI) spacers create membranes that are better barriers to movement of solutes > 70 kDa in size than polymethyl me...

journal_title：Annals of biomedical engineering

authors： Toth Z,Roi M,Evans E,Watson JT,Nicolaou D,McBride-Gagyi S

更新日期：2019-01-01 00:00:00

abstract：:We developed muscle-tendon models incorporating Hill-type structure and length-dependent coupling between activation and velocity. The models were evaluated in electrically stimulated cat soleus muscles. Dynamic model parameters were estimated by a nonlinear parameter estimation algorithm from input-output data obtain...

journal_title：Annals of biomedical engineering

authors： Shue GH,Crago PE

更新日期：1998-05-01 00:00:00

abstract：:Dexterity of robots is highly required when it comes to integration for medical applications. Major efforts have been conducted to increase the dexterity at the distal parts of medical robots. This paper reports on developments toward integrating biocompatible conducting polymers (CP) into inherently dexterous concent...

journal_title：Annals of biomedical engineering

authors： Chikhaoui MT,Benouhiba A,Rougeot P,Rabenorosoa K,Ouisse M,Andreff N

更新日期：2018-10-01 00:00:00