Cardiac Multi-detector CT Segmentation Based on Multiscale Directional Edge Detector and 3D Level Set.

Abstract:

:Extraction of the cardiac surfaces of interest from multi-detector computed tomographic (MDCT) data is a pre-requisite step for cardiac analysis, as well as for image guidance procedures. Most of the existing methods need manual corrections, which is time-consuming. We present a fully automatic segmentation technique for the extraction of the right ventricle, left ventricular endocardium and epicardium from MDCT images. The method consists in a 3D level set surface evolution approach coupled to a new stopping function based on a multiscale directional second derivative Gaussian filter, which is able to stop propagation precisely on the real boundary of the structures of interest. We validated the segmentation method on 18 MDCT volumes from healthy and pathologic subjects using manual segmentation performed by a team of expert radiologists as gold standard. Segmentation errors were assessed for each structure resulting in a surface-to-surface mean error below 0.5 mm and a percentage of surface distance with errors less than 1 mm above 80%. Moreover, in comparison to other segmentation approaches, already proposed in previous work, our method presented an improved accuracy (with surface distance errors less than 1 mm increased of 8-20% for all structures). The obtained results suggest that our approach is accurate and effective for the segmentation of ventricular cavities and myocardium from MDCT images.

journal_name

Ann Biomed Eng

authors

Antunes S,Esposito A,Palmisano A,Colantoni C,Cerutti S,Rizzo G

doi

10.1007/s10439-015-1422-4

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

1487-501

issue

5

eissn

0090-6964

issn

1573-9686

pii

10.1007/s10439-015-1422-4

journal_volume

44

pub_type

杂志文章,随机对照试验
  • Quadratic phase coupling as a quantitative measure for the developing hippocampal formation.

    abstract::This paper presents the bispectral analysis of the ontogeny of the hippocampal EEG recorded from the dentate gyrus and CA1, the primary sites that generate theta (theta) rhythm. The hippocampal EEG was collected during the vigilance state of rapid eye movement (REM) sleep of freely moving rats at 15, 30 and 90 days of...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.43

    authors: Ning T,Bronzino JD

    更新日期:1998-07-01 00:00:00

  • Partial Bone Formation in Additive Manufactured Porous Implants Reduces Predicted Stress and Danger of Fatigue Failure.

    abstract::New porous implant designs made possible by additive manufacturing allow for increased osseointegration, potentially improving implant performance and longevity for patients that require massive bone implants. The aim of this study was to evaluate how implantation and the strain distribution in the implant affect the ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-019-02369-z

    authors: Cheong VS,Fromme P,Coathup MJ,Mumith A,Blunn GW

    更新日期:2020-01-01 00:00:00

  • Behavior of human mesenchymal stem cells in fibrin-based vascular tissue engineering constructs.

    abstract::A limitation of current tissue engineering vascular graft technology is the provision of an expandable, autologous cell source. By harnessing the multipotency of mesenchymal stem cells (MSC), it is hoped that functional vascular cells can be produced. To date, a range of 2D and 3D environments have been investigated f...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-010-9912-x

    authors: O'Cearbhaill ED,Murphy M,Barry F,McHugh PE,Barron V

    更新日期:2010-03-01 00:00:00

  • Transport Analysis of Engineered Liver Tissue Fabricated Using a Capsule-Based, Modular Approach.

    abstract::The bioinspired, microscale tissue engineering approach has emerged in recent years as a promising alternative to preformed scaffolds. Using this approach, complex tissues and organs can be efficiently engineered from microscale modules to replicate the intricate architecture and physiology of vascularized organs and ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-018-02192-y

    authors: Annamalai RT,Matthew HWT

    更新日期:2019-05-01 00:00:00

  • A review of the role of the partial pressure of carbon dioxide in mechanically loaded tissues: the canary in the cage singing in tune with the pressure ulcer mantra.

    abstract::Pressure ulcers (PUs) can occur in any situations where people are subjected to non-uniform distribution of pressure over a prolonged period. They can have devastating effects on the patients' well-being and in extreme conditions can prove fatal. In addition to traditional wisdom implicating mechanically induced ischa...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章,评审

    doi:10.1007/s10439-014-1233-z

    authors: Mirtaheri P,Gjøvaag T,Worsley PR,Bader DL

    更新日期:2015-02-01 00:00:00

  • Interstitial stress and fluid pressure within a growing tumor.

    abstract::A solid tumor is composed of a population of cells that is expanding as a result of cell division. With dense cell packing, the solid matrix of the interstitial tissue is subject to residual stress. In addition, elevated interstitial fluid pressure (IFP) has been reported by researchers for a number of solid tumors. T...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.1554923

    authors: Sarntinoranont M,Rooney F,Ferrari M

    更新日期:2003-03-01 00:00:00

  • Characterizing the variability of system kernel and input estimates.

    abstract::The identification of the input to, or kernels of, a system using nonparametric representations and least-squares estimation is becoming increasingly popular. Nonparametric representations avoid making a priori assumptions about the input or having detailed knowledge about the system, and only need to guarantee known ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.110

    authors: Verotta D

    更新日期:1998-09-01 00:00:00

  • Contractile responses in arteries subjected to hypertensive pressure in seven-day organ culture.

    abstract::Early stage changes in hypertensive arteries have a significant effect on the long-term adaptation of the arteries. Compared to the long-term adaptation, little is known about the early dimensional and functional changes in hypertensive arteries in the first few days of hypertension. To study the early stage changes i...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.1376391

    authors: Han HC,Ku DN

    更新日期:2001-06-01 00:00:00

  • Research report: learning styles of biomedical engineering students.

    abstract::Examining students' learning styles can yield information useful to the design of learning activities, courses, and curricula. A variety of measures have been used to characterize learning styles, but the literature contains little information specific to biomedical engineering (BMEN) students. We, therefore, utilized...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.1512677

    authors: Dee KC,Nauman EA,Livesay GA,Rice J

    更新日期:2002-09-01 00:00:00

  • Development of a Three-Dimensional Adipose Tissue Model for Studying Embryonic Exposures to Obesogenic Chemicals.

    abstract::Obesity is a rising issue especially in the United States that can lead to heart problems, type II diabetes, and respiratory problems. Since the 1970s, obesity rates in the United States have more than doubled in adults and children. Recent evidence suggests that exposure to certain chemicals, termed "obesogens," in u...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-016-1752-x

    authors: Wang RY,Abbott RD,Zieba A,Borowsky FE,Kaplan DL

    更新日期:2017-07-01 00:00:00

  • Biomechanical Characterisation of the Human Auricular Cartilages; Implications for Tissue Engineering.

    abstract::Currently, autologous cartilage provides the gold standard for auricular reconstruction. However, synthetic biomaterials offer a number of advantages for ear reconstruction including decreased donor site morbidity and earlier surgery. Critical to implant success is the material's mechanical properties as this affects ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-016-1688-1

    authors: Griffin MF,Premakumar Y,Seifalian AM,Szarko M,Butler PE

    更新日期:2016-12-01 00:00:00

  • A device for imposing cyclic strain to cells growing on implant alloys.

    abstract::The objective of this study was to develop a unique device for applying well-characterized cyclic, strain to cells growing on implant alloys. The device is based on the four-point bending principle and utilizes an electric motor, belt, and cam system to cyclically deflect a commercially pure titanium plate with cell c...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.1529195

    authors: Winter LC,Gilbert JA,Elder SH,Bumgardner JD

    更新日期:2002-11-01 00:00:00

  • Coupling of a 3D finite element model of cardiac ventricular mechanics to lumped systems models of the systemic and pulmonic circulation.

    abstract::In this study we present a novel, robust method to couple finite element (FE) models of cardiac mechanics to systems models of the circulation (CIRC), independent of cardiac phase. For each time step through a cardiac cycle, left and right ventricular pressures were calculated using ventricular compliances from the FE...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-006-9212-7

    authors: Kerckhoffs RC,Neal ML,Gu Q,Bassingthwaighte JB,Omens JH,McCulloch AD

    更新日期:2007-01-01 00:00:00

  • A review of approaches to mobility telemonitoring of the elderly in their living environment.

    abstract::Rapid technological advances have prompted the development of a wide range of telemonitoring systems to enable the prevention, early diagnosis and management, of chronic conditions. Remote monitoring can reduce the amount of recurring admissions to hospital, facilitate more efficient clinical visits with objective res...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章,评审

    doi:10.1007/s10439-005-9068-2

    authors: Ní Scanaill C,Carew S,Barralon P,Noury N,Lyons D,Lyons GM

    更新日期:2006-04-01 00:00:00

  • Tracking of Drug Release and Material Fate for Naturally Derived Omega-3 Fatty Acid Biomaterials.

    abstract::In vitro and in vivo studies were conducted on omega-3 fatty acid-derived biomaterials to determine their utility as an implantable material for adhesion prevention following soft tissue hernia repair and as a means to allow for the local delivery of antimicrobial or antibiofilm agents. Naturally derived biomaterials ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-015-1489-y

    authors: Faucher KM,Artzi N,Beck M,Beckerman R,Moodie G,Albergo T,Conroy S,Dale A,Corbeil S,Martakos P,Edelman ER

    更新日期:2016-03-01 00:00:00

  • Effects of External and Internal Hyperthermia on LDL Transport and Accumulation Within an Arterial Wall in the Presence of a Stenosis.

    abstract::Effects of hyperthermia on transport of low-density lipoprotein (LDL) through a stenosed arterial wall are analyzed comprehensively in the present work. The realistic and pertinent aspects of an arterial wall is represented by a multi-layer model, with a proper representation of the thickened intima region due to the ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-014-1196-0

    authors: Iasiello M,Vafai K,Andreozzi A,Bianco N,Tavakkoli F

    更新日期:2015-07-01 00:00:00

  • Multidirectional pelvic floor muscle strength measurement.

    abstract::Pelvic floor muscle (PFM) strength measurement provides useful information for the study of pelvic floor dysfunctions. Vaginal digital palpation, intravaginal pressure measurements, and the use of a dynamometric speculum represent currently available clinical methods for evaluating PFM strength. However, none of these...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-009-9728-8

    authors: Saleme CS,Rocha DN,Del Vecchio S,Silva Filho AL,Pinotti M

    更新日期:2009-08-01 00:00:00

  • An optimization-based simultaneous approach to the determination of muscular, ligamentous, and joint contact forces provides insight into musculoligamentous interaction.

    abstract::Typical inverse dynamics approaches to the calculation of muscle, ligament, and joint contact forces are based on a step-wise solution of the equations of motion. This approach is therefore limited in its ability to provide insight as to the muscular, ligamentous, and articular interactions that create joint stability...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-011-0303-8

    authors: Cleather DJ,Bull AM

    更新日期:2011-07-01 00:00:00

  • Neurite outgrowth on a DNA crosslinked hydrogel with tunable stiffnesses.

    abstract::Mechanical cues arising from extracellular matrices greatly affect cellular properties, and hence, are of significance in designing biomaterials. In this study, a DNA crosslinked hydrogel was employed to examine cellular responses of spinal cord neurons to substrate compliances. Using DNA as crosslinkers in polymeric ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-008-9530-z

    authors: Jiang FX,Yurke B,Firestein BL,Langrana NA

    更新日期:2008-09-01 00:00:00

  • The effect of visual and sensory performance on head impact biomechanics in college football players.

    abstract::The development of prevention strategies is critical to address the rising prevalence of sport-related concussions. Visual and sensory performance may influence an individual's ability to interpret environmental cues, anticipate opponents' actions, and create appropriate motor responses limiting the severity of an imp...

    journal_title:Annals of biomedical engineering

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10439-013-0881-8

    authors: Harpham JA,Mihalik JP,Littleton AC,Frank BS,Guskiewicz KM

    更新日期:2014-01-01 00:00:00

  • Muscle-tendon model with length history-dependent activation-velocity coupling.

    abstract::We developed muscle-tendon models incorporating Hill-type structure and length-dependent coupling between activation and velocity. The models were evaluated in electrically stimulated cat soleus muscles. Dynamic model parameters were estimated by a nonlinear parameter estimation algorithm from input-output data obtain...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.93

    authors: Shue GH,Crago PE

    更新日期:1998-05-01 00:00:00

  • Simulated epicardial potential maps during paced activation reflect myocardial fibrous structure.

    abstract::Using a three-dimensional propagation model of the human ventricular myocardium, we studied the role of fibrous structure in generating epicardial potential maps. This model represents the myocardium as an anisotropic bidomain with an equal anisotropy ratio, and it incorporates a realistic representation of anatomical...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.73

    authors: Hren R,Nenonen J,Horácek BM

    更新日期:1998-11-01 00:00:00

  • Assessment of ventricular contractility during cardiac magnetic resonance imaging examinations using normalized maximal ventricular power.

    abstract::Normalized maximal ventricular power (nPWRmax) is an index of cardiac function which measures the innate blood pumping ability, or contractility, of the left ventricle (LV), and its noninvasive assessment could prove useful in a variety of patients. nPWRmax is defined as the maximum instantaneous product of LV pressur...

    journal_title:Annals of biomedical engineering

    pub_type: 临床试验,杂志文章

    doi:10.1114/1.1415530

    authors: Setser RM,Sayre K,Flacke S,Chia J,Lunn K,Lorenz CH

    更新日期:2001-11-01 00:00:00

  • Errors caused by combination of Di-4 ANEPPS and Fluo3/4 for simultaneous measurements of transmembrane potentials and intracellular calcium.

    abstract::Intracellular calcium concentration and transmembrane potentials are two important measurements used to study the mechanisms of cardiac activity. Fluorescent dyes have been used to measure these separately but not simultaneously in cardiac tissue. Fluo-3 and Fluo-4 (a recently improved version of Fluo-3) have been use...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.198

    authors: Johnson PL,Smith W,Baynham TC,Knisley SB

    更新日期:1999-07-01 00:00:00

  • Intracellular trafficking considerations in the development of natural ligand-drug molecular conjugates for cancer.

    abstract::Overexpressed receptors, characteristic of many cancers, have been targeted by various researchers to achieve a more specific treatment for cancer. A common approach is to use the natural ligand for the overexpressed receptor as a cancer-targeting agent which can deliver a chemically or genetically conjugated toxic mo...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章,评审

    doi:10.1007/s10439-011-0280-y

    authors: Yoon DJ,Liu CT,Quinlan DS,Nafisi PM,Kamei DT

    更新日期:2011-04-01 00:00:00

  • Comparison of Covered Laser-cut and Braided Respiratory Stents: From Bench to Pre-Clinical Testing.

    abstract::Lung cancer patients often suffer from severe airway stenosis, the symptoms of which can be relieved by the implantation of stents. Different respiratory stents are commercially available, but the impact of their mechanical performance on tissue responses is not well understood. Two novel laser-cut and hand-braided ni...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-019-02278-1

    authors: Thiebes AL,McGrath DJ,Kelly N,Sweeney CA,Kurtenbach K,Gesché VN,Clauser J,O'Brien B,Bruzzi M,McHugh PE,Jockenhoevel S,Cornelissen CG

    更新日期:2019-08-01 00:00:00

  • Reporter Scaffolds for Clinically Relevant Cell Transplantation Studies.

    abstract::There are a number of cell therapies that are either in clinical trials or moving toward clinical trials, particularly for diseases of the retina. One of the challenges with cell therapies is tracking the status of cells over time. Genetic manipulation can facilitate this, but it can limit the clinical application of ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-019-02393-z

    authors: Bolger M,Groynom R,Bogie K,Lavik E

    更新日期:2020-07-01 00:00:00

  • A fuzzy pattern recognition method to classify esophageal motility records.

    abstract::Analysis and classification of esophageal motility records were investigated using signal processing and fuzzy-set pattern recognition techniques. A set of parameters has been extracted from the raw records and has previously been used as characterizing features. Improvements to these procedures were obtained by extra...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02368227

    authors: Abou-Chadi FE,Ezzat FA,Sif el-Din AA

    更新日期:1994-01-01 00:00:00

  • Tissue remodeling of rat pulmonary artery in hypoxic breathing. II. Course of change of mechanical properties.

    abstract::When cells and the matrix of a tissue remodel, the mechanical properties of the tissue do change. The mechanical properties are expressed by constitutive equations. In this article the remodeling of the constitutive equation of the pulmonary artery is studied. The remodeling was induced in a rat breathing a gas whose ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.1380417

    authors: Huang W,Delgado-West D,Wu JT,Fung YC

    更新日期:2001-01-01 00:00:00

  • Wall Shear Stress Topological Skeleton Independently Predicts Long-Term Restenosis After Carotid Bifurcation Endarterectomy.

    abstract::Wall Shear Stress (WSS) topological skeleton, composed by fixed points and the manifolds linking them, reflects the presence of blood flow features associated to adverse vascular response. However, the influence of WSS topological skeleton on vascular pathophysiology is still underexplored. This study aimed to identif...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-020-02607-9

    authors: Morbiducci U,Mazzi V,Domanin M,De Nisco G,Vergara C,Steinman DA,Gallo D

    更新日期:2020-12-01 00:00:00