Theory of the oscillometric maximum and the systolic and diastolic detection ratios.

abstract：:We propose a multifrequency energy transmission scheme for annular phased arrays in deep-body hyperthermia. The problem of frequency dependent resonance effects reported in hyperthermia phantom calibration studies, leading to skewed energy deposition patterns and unwanted energy maxima (hot spots), is addressed by com...

journal_title：Annals of biomedical engineering

authors： Jacobsen S,Melandsø F

更新日期：2002-01-01 00:00:00

abstract：:Recently, we reported that tethering and rolling of neutrophils in shear flow over a substrate of E-selectin signals activation of beta 2-integrins and firm adhesion via an intracellular signaling pathway involving phosphorylation of p38 MAP kinase. In the current study the objective was to examine the molecular mecha...

journal_title：Annals of biomedical engineering

authors： Hentzen E,McDonough D,McIntire L,Smith CW,Goldsmith HL,Simon SI

更新日期：2002-09-01 00:00:00

abstract：:Recent developments in computational modeling of cochlear implantation are promising to study in silico the performance of the implant before surgery. However, creating a complete computational model of the patient's anatomy while including an external device geometry remains challenging. To address such a challenge, ...

journal_title：Annals of biomedical engineering

authors： Mangado N,Ceresa M,Duchateau N,Kjer HM,Vera S,Dejea Velardo H,Mistrik P,Paulsen RR,Fagertun J,Noailly J,Piella G,González Ballester MÁ

更新日期：2016-08-01 00:00:00

abstract：:The scarcity of data available on the best approach for pulmonary fetal valve replacement or implantation necessitate an investigation on whether practices using adult transcatheter valves could be translated to fetal applications. The objective of this study is to evaluate the hemodynamic characteristics and the turb...

journal_title：Annals of biomedical engineering

authors： Hatoum H,Gooden S,Heitkemper M,Blum KM,Zakko J,Bocks M,Yi T,Wu YL,Wang Y,Breuer CK,Dasi LP

更新日期：2020-06-01 00:00:00

abstract：:Potential human and environmental hazards resulting from the exposure of living organisms to silver nanoparticles (Ag NPs) have been the subject of intensive discussion in the last decade. Despite the growing use of Ag NPs in biomedical applications, a quantification of the toxic effects as a function of the total sil...

journal_title：Annals of biomedical engineering

authors： Poli D,Mattei G,Ucciferri N,Ahluwalia A

更新日期：2020-04-01 00:00:00

abstract：:We have studied the interaction of high frequency jet ventilation with cardiovascular pressures and flows. Results in dogs show that the amplitude of all intrathoracic pressures and flows fluctuate with a frequency equal to the difference between the heart rate and ventilator rate. The magnitude of this amplitude vari...

journal_title：Annals of biomedical engineering

authors： Mitzner W,Gioia F,Weinmann GG,Robotham JL,Ehrlich W

更新日期：1987-01-01 00:00:00

abstract：:The toxic or therapeutic effect of an inhaled aerosol is highly dependent upon the site and extent of deposition in the lung. A novel MRI-based method was used to quantify the spatial distribution of particles in the rat lung. Rats were exposed to 0.95 μm-diameter iron oxide particles in a controlled manner (N = 6) or...

journal_title：Annals of biomedical engineering

authors： Oakes JM,Scadeng M,Breen EC,Prisk GK,Darquenne C

更新日期：2013-05-01 00:00:00

abstract：:The aim of this study was to test the differentiative effects of osteoblasts after treatment with a static magnetic field (SMF). MG63 osteoblast-like cells were exposed to a 0.4-T SMF. The differentiation markers were assessed by observing the changes in alkaline phosphatase activity and electron microscopy images. Me...

journal_title：Annals of biomedical engineering

authors： Chiu KH,Ou KL,Lee SY,Lin CT,Chang WJ,Chen CC,Huang HM

更新日期：2007-11-01 00:00:00

abstract：:Abdominal aortic aneurysms occur in as much as 2-3% of the population, and their rupture produces a mortality rate of 78-94% (1), causing 15,000 deaths per year in the U.S. alone. As an investigation into the mechanical factors that lead to aneurysm rupture, flow field measurements are presented for steady flow throug...

journal_title：Annals of biomedical engineering

authors： Asbury CL,Ruberti JW,Bluth EI,Peattie RA

更新日期：1995-01-01 00:00:00

abstract：:Due to its unique non-invasive microstructure probing capabilities, diffusion tensor imaging (DTI) constitutes a valuable tool in the study of fiber orientation in skeletal muscles. By implementing a DTI sequence with judiciously chosen directional encoding to quantify in vivo the microarchitectural properties in the ...

journal_title：Annals of biomedical engineering

authors： Karampinos DC,King KF,Sutton BP,Georgiadis JG

更新日期：2009-12-01 00:00:00

abstract：:Optimal treatment of proximal humerus fractures remains controversial. Locking plates offer theoretical advantages but are associated with complications in the clinic. This study aimed to perform parametric design optimisation of proximal humerus plates to enhance their mechanical performance. A finite element (FE) mo...

journal_title：Annals of biomedical engineering

authors： Jabran A,Peach C,Zou Z,Ren L

更新日期：2019-02-01 00:00:00

abstract：:Blunt carotid artery injuries occur in 0.3% of blunt injured patients and may lead to devastating neurological consequences. However, arterial mechanics leading to internal layer subfailure have not been quantified. Twenty-two human carotid artery segments and 18 porcine thoracic aorta segments were opened to expose t...

journal_title：Annals of biomedical engineering

authors： Stemper BD,Yoganandan N,Sinson GP,Gennarelli TA,Stineman MR,Pintar FA

更新日期：2007-02-01 00:00:00

abstract：:This study investigated the effect of mechanical strain on solute diffusion in human TMJ discs (mean cadaver age 77.8) using the electrical conductivity method. The electrical conductivity, as well as small ion diffusivity, of male and female TMJ discs was determined under three compressive strains. In the male group,...

journal_title：Annals of biomedical engineering

authors： Wright GJ,Kuo J,Shi C,Bacro TR,Slate EH,Yao H

更新日期：2013-11-01 00:00:00

abstract：:Fingertips wrinkle due to long exposure to water. The biological reason for this morphological change is unclear and still not fully understood. There are two main hypotheses for the underlying mechanism of fingertip wrinkling: the 'shrink' model (in which the wrinkling is driven by the contraction of the lower layers...

journal_title：Annals of biomedical engineering

authors： Sáez P,Zöllner AM

更新日期：2017-04-01 00:00:00

abstract：:Premature ovarian insufficiency (POI) is a major complication of cytotoxic treatments due to extreme ovarian sensitivity to chemotherapy and radiation. In pediatric cancer patients modern therapy has improved the long-term survival to over 80% in the United States. However, these cancer survivors face long-term health...

journal_title：Annals of biomedical engineering

authors： David A,Day JR,Cichon AL,Lefferts A,Cascalho M,Shikanov A

更新日期：2017-07-01 00:00:00

abstract：:We hypothesize that variations of body anthropometry, conjointly with the bone strength, determine the risk of hip fracture. To test the hypothesis, we compared, in a simulated sideways fall, the hip impact energy to the energy needed to fracture the femur. Ten femurs from elderly donors were tested using a novel drop...

journal_title：Annals of biomedical engineering

authors： Palanca M,Perilli E,Martelli S

更新日期：2020-11-12 00:00:00

abstract：:Wiener static nonlinear system identification was used to study the linear dynamics and static nonlinearities in the response of skin and underlying tissue under indentation in vivo. A device capable of measuring the dynamic mechanical properties of bulk skin tissue was developed and it incorporates a custom-built Lor...

journal_title：Annals of biomedical engineering

authors： Chen Y,Hunter IW

更新日期：2012-10-01 00:00:00

abstract：:Basic fibroblast growth factor (FGF-2) is a potent angiogenic growth factor involved in the development of diseases such as cancer, atherosclerosis, and heart and limb ischemia, as well as normal wound healing and tissue development. Despite being one of the most heavily studied angiogenic growth factors, the binding ...

journal_title：Annals of biomedical engineering

authors： Filion RJ,Popel AS

更新日期：2004-05-01 00:00:00

abstract：:Tumor vasculature damage induced by various thermal treatments has been studied in vivo via laser confocal microscopy. Murine mammary carcinoma 4T1 was implanted in the nude mice dorsal skin fold window chamber. The implanted tumor was treated by alternate cooling and heating. Results showed that the treatment was muc...

journal_title：Annals of biomedical engineering

authors： Shen Y,Liu P,Zhang A,Xu LX

更新日期：2008-08-01 00:00:00

abstract：:This article presents a computer-aided detection system for capsule endoscopy (CE) images using contourlet-based color textural features to recognize tumors in the digestive tract. As tumor exhibits rich information in color texture, a novel color texture feature based on contourlet transform is proposed to describe c...

journal_title：Annals of biomedical engineering

authors： Li B,Meng MQ

更新日期：2011-12-01 00:00:00

abstract：:Radiation applied for therapy and diagnostics damages molecular/atomic couples of biotissues, bones being among them. As a result, electron peculiarities and mechanical behavior of the latter are altered. Correlation between strength of the irradiated bone and its electron features explored due to photo- and exoelectr...

journal_title：Annals of biomedical engineering

authors： Dekhtyar Y

更新日期：2001-12-01 00:00:00

abstract：:In this paper, we present the application of a semi-global inverse method for determining material parameters of biological tissues. The approach is based on the successive response surface method, and is illustrated by fitting constitutive parameters to two nonlinear anisotropic constitutive equations, one for aortic...

journal_title：Annals of biomedical engineering

authors： Einstein DR,Freed AD,Stander N,Fata B,Vesely I

更新日期：2005-12-01 00:00:00

abstract：:Gas transfer through hollow fiber membranes (HFMs) can be increased via fiber oscillation. Prior work, however, does not directly translate to present-day, full-scale artificial lungs. This in vitro study characterized the effects of HFM oscillations on oxygenation and hemolysis for a pediatric-sized HFM bundle. Effec...

journal_title：Annals of biomedical engineering

authors： Orizondo RA,Gino G,Sultzbach G,Madhani SP,Frankowski BJ,Federspiel WJ

更新日期：2018-05-01 00:00:00

abstract：:To meet demands of vascular reconstruction, there is a need for prosthetic alternatives to natural blood vessels. Here we explored a new conduit fabrication approach. Macroporous, gelatin microcarriers laden with human umbilical vein endothelial cells and aortic smooth muscle cells were dispensed into tubular agarose ...

journal_title：Annals of biomedical engineering

authors： Twal WO,Klatt SC,Harikrishnan K,Gerges E,Cooley MA,Trusk TC,Zhou B,Gabr MG,Shazly T,Lessner SM,Markwald RR,Argraves WS

更新日期：2014-07-01 00:00:00

abstract：:Three animal models were evaluated in this study involving head impacts of the rat, including the Marmarou drop-weight and two momentum-exchange techniques. In series 1, 36 Wistar rats were hit on the side of the free-moving head using Marmarou's 450 g impact mass at 4.4, 5.4, and 6.3 m/s. Head acceleration was measur...

journal_title：Annals of biomedical engineering

authors： Viano DC,Hamberger A,Bolouri H,Säljö A

更新日期：2012-01-01 00:00:00

abstract：:Elastin is an essential component of arteries which provides structural integrity and instructs smooth muscle cells to adopt a quiescent state. Despite interaction of endothelial cells with elastin in the internal elastic lamina, the potential for exploiting this interaction therapeutically has not been explored in de...

journal_title：Annals of biomedical engineering

authors： Wilson BD,Gibson CC,Sorensen LK,Guilhermier MY,Clinger M,Kelley LL,Shiu YT,Li DY

更新日期：2011-01-01 00:00:00

abstract：:In 12 dogs anesthetised with alpha-chloralose and urethane, and beta-adrenergic blocked with propranolol, the cervical vagi were stimulated for 60 seconds with supramaximal constant current pulses at frequencies between 2.0 and 10 Hz. The time course of the recovery of the cardiac period response, after cessation of v...

journal_title：Annals of biomedical engineering

authors： Celler BG,Lovell NH

更新日期：1991-01-01 00:00:00

abstract：:This paper presents an in vitro temperature mapping study of bovine cardiac tissue during radiofrequency ablation. The objectives were to: (i) develop a technique for measuring the spatial and temporal temperature distribution in the tissue and in the blood during ablation, and (ii) use the temperature measurements to...

journal_title：Annals of biomedical engineering

authors： Jain MK,Wolf PD

更新日期：2000-09-01 00:00:00

abstract：:Quantifying injury tolerance for concussion is complicated by variability in the type, severity, and time course of post-injury physiological and behavioral changes. The current study outlined acute and chronic changes in behavioral metrics following rotational acceleration-induced concussion in rats. The Medical Coll...

journal_title：Annals of biomedical engineering

authors： Stemper BD,Shah AS,Chiariello R,Olsen CM,Budde MD,Glavaski-Joksimovic A,McCrea M,Kurpad SN,Pintar FA

更新日期：2016-11-01 00:00:00

abstract：:User preferences need to be taken into account in order to be able to design devices that will gain acceptance both in a clinical and home setting. Sensor systems become redundant if patients or clinicians do not want to work with them. The aim of this systematic review was to determine both patients' and clinicians' ...

journal_title：Annals of biomedical engineering

authors： Bergmann JH,McGregor AH

更新日期：2011-09-01 00:00:00