Abstract:
:The aim of this study was to test the differentiative effects of osteoblasts after treatment with a static magnetic field (SMF). MG63 osteoblast-like cells were exposed to a 0.4-T SMF. The differentiation markers were assessed by observing the changes in alkaline phosphatase activity and electron microscopy images. Membrane fluidity was used to evaluate alterations in the biophysical properties of the cellular membranes after the SMF simulation. Our results show that SMF exposure increases alkaline phosphatase activity and extracellular matrix release in MG63 cells. On the other hand, MG63 cells exposed to a 0.4-T SMF exhibited a significant increase in fluorescence anisotropy at 6 h, with a significant reduction in the proliferation effects of growth factors noted at 24 h. Based on these findings, the authors suggest that one of the possible mechanisms that SMF affects osteoblastic maturation is by increasing the membrane rigidity and reducing the proliferation-promoting effects of growth factors at the membrane domain.
journal_name
Ann Biomed Engjournal_title
Annals of biomedical engineeringauthors
Chiu KH,Ou KL,Lee SY,Lin CT,Chang WJ,Chen CC,Huang HMdoi
10.1007/s10439-007-9370-2subject
Has Abstractpub_date
2007-11-01 00:00:00pages
1932-9issue
11eissn
0090-6964issn
1573-9686journal_volume
35pub_type
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
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journal_title:Annals of biomedical engineering
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1007/s10439-008-9564-2
更新日期:2008-12-01 00:00:00
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doi:10.1007/s10439-015-1340-5
更新日期:2015-06-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/BF02368054
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journal_title:Annals of biomedical engineering
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journal_title:Annals of biomedical engineering
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更新日期:2018-12-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1114/1.1541014
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journal_title:Annals of biomedical engineering
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更新日期:2016-11-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-011-0329-y
更新日期:2011-09-01 00:00:00
abstract::Despite the use of helmets in American football, brain injuries are still prevalent. To reduce the burden of these injuries, novel impact mitigation systems are needed. The Vicis Zero1 (VZ1) American football helmet is unique in its use of multi-directional buckling structures sandwiched between a deformable outer she...
journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-020-02472-6
更新日期:2020-05-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-011-0380-8
更新日期:2011-12-01 00:00:00
abstract::A rigorous analysis of blood flow must be based on the branching pattern and vascular geometry of the full vascular circuit of interest. It is experimentally difficult to reconstruct the entire vascular circuit of any organ because of the enormity of the vessels. The objective of the present study was to develop a nov...
journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-005-5758-z
更新日期:2005-08-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-012-0733-y
更新日期:2013-07-01 00:00:00
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journal_title:Annals of biomedical engineering
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doi:10.1007/s10439-019-02333-x
更新日期:2020-01-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-018-2041-7
更新日期:2018-09-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章,评审
doi:10.1007/s10439-011-0280-y
更新日期:2011-04-01 00:00:00
abstract::Millions of people worldwide are diagnosed each year with valvular heart disease, resulting in hundreds of thousands of valve replacement operations. Prosthetic valve replacements are designed to correct narrowing or backflow through the valvular orifice. Although commonly used, these therapies have serious disadvanta...
journal_title:Annals of biomedical engineering
pub_type: 杂志文章,评审
doi:10.1007/s10439-010-0148-6
更新日期:2010-11-01 00:00:00
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journal_title:Annals of biomedical engineering
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journal_title:Annals of biomedical engineering
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
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更新日期:1997-03-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-007-9286-x
更新日期:2007-05-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/BF02684228
更新日期:1996-09-01 00:00:00
abstract::We seek to construct physical and mathematical models of life. Such models allow us to test our understanding of how living systems function and how they respond to human imposed stimuli. One system is a genomically and chemically complete model of a minimal cell. This cell is a hypothetical bacterium with the fewest ...
journal_title:Annals of biomedical engineering
pub_type: 杂志文章,评审
doi:10.1007/s10439-012-0567-7
更新日期:2012-07-01 00:00:00
abstract::Measurement of the instantaneous pressure-volume relationship of the left ventricle is fundamental to the study of ventricular mechanics. In order to effectively investigate this relationship, it is necessary to vary and control the time course of ventricular volume change in a variety of prescribed manners. In the pa...
journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/BF02367387
更新日期:1982-01-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 临床试验,杂志文章
doi:10.1007/s10439-018-02153-5
更新日期:2019-02-01 00:00:00
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journal_title:Annals of biomedical engineering
pub_type: 杂志文章
doi:10.1007/s10439-015-1543-9
更新日期:2016-08-01 00:00:00
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journal_title:Annals of biomedical engineering
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更新日期:2016-05-01 00:00:00
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journal_title:Annals of biomedical engineering
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更新日期:2005-02-01 00:00:00