Increases of corporal temperature as a risk factor of atherosclerotic plaque instability.

abstract：:Tumor vasculature damage induced by various thermal treatments has been studied in vivo via laser confocal microscopy. Murine mammary carcinoma 4T1 was implanted in the nude mice dorsal skin fold window chamber. The implanted tumor was treated by alternate cooling and heating. Results showed that the treatment was muc...

journal_title：Annals of biomedical engineering

authors： Shen Y,Liu P,Zhang A,Xu LX

更新日期：2008-08-01 00:00:00

abstract：:Statistical methods are increasingly used in biomechanics for studying bone geometry, bone density distribution and function in the population. However, relating population-based bone variation to strain during activity is computationally challenging. Here, we describe a new method for calculating strain in a populati...

journal_title：Annals of biomedical engineering

authors： Ziaeipoor H,Taylor M,Martelli S

更新日期：2020-06-01 00:00:00

abstract：:Continuous gradients exist at osteochondral interfaces, which may be engineered by applying spatially patterned gradients of biological cues. In the present study, a protein-loaded microsphere-based scaffold fabrication strategy was applied to achieve spatially and temporally controlled delivery of bioactive signals i...

journal_title：Annals of biomedical engineering

authors： Dormer NH,Singh M,Wang L,Berkland CJ,Detamore MS

更新日期：2010-06-01 00:00:00

abstract：:Electrical potentials in mechanically loaded bone have been implicated as signals in the bone remodeling cycle. Recently, interest has grown in exploiting this phenomenon to develop electrically active ceramics for implantation in hard tissue which may induce improved biological responses. Both polarized hydroxyapatit...

journal_title：Annals of biomedical engineering

authors： Baxter FR,Bowen CR,Turner IG,Dent AC

更新日期：2010-06-01 00:00:00

abstract：:Pressure ulcer risk assessment might be optimized by incorporating the soft tissue reaction to mechanical loading in the currently used risk assessment scales. Cytokines, like IL-1alpha, IL-1RA, IL-8, and TNF-alpha, might be used to determine this tissue reaction, since they are released after 24 h of mechanical loadi...

journal_title：Annals of biomedical engineering

authors： Cornelissen LH,Bronneberg D,Bader DL,Baaijens FP,Oomens CW

更新日期：2009-05-01 00:00:00

abstract：:The effects of wave propagation phenomena, namely global reflection coefficient (gamma G[omega]) and pulse wave velocity (Cph), are studied in a model of the coupled left ventricle/arterial system. The left ventricle consists of a time-varying elastance, while the arterial system is modeled as a single, uniform, elast...

journal_title：Annals of biomedical engineering

authors： Berger DS,Li JK,Noordergraaf A

更新日期：1995-11-01 00:00:00

abstract：:The compression of blood vessels by surrounding tissue is an important problem in hemodynamics, most prominently in studies relating to the heart. In this study we consider a long tube of elliptic cross section as an idealization of the geometry of a compressed blood vessel. An exact solution of the governing equation...

journal_title：Annals of biomedical engineering

authors： Haslam M,Zamir M

更新日期：1998-09-01 00:00:00

abstract：:Tissue engineering strategies have utilized a wide spectrum of synthetic and naturally-derived scaffold materials. Synthetic scaffolds are better defined and offer the ability to precisely and reproducibly control their properties, while naturally-derived scaffolds typically have inherent biological and structural pro...

journal_title：Annals of biomedical engineering

authors： Allen AB,Priddy LB,Li MT,Guldberg RE

更新日期：2015-03-01 00:00:00

abstract：:The nose is the front line defender of the respiratory system. Unsteady simulations in three-dimensional models have been developed to study transport patterns in the human nose and its overall air-conditioning capacity. The results suggested that the healthy nose can efficiently provide about 90% of the heat and the ...

journal_title：Annals of biomedical engineering

authors： Naftali S,Rosenfeld M,Wolf M,Elad D

更新日期：2005-04-01 00:00:00

abstract：:A role for mechanical stimulation in the control of cell fate has been proposed and mechanical conditioning of mesenchymal stem cells (MSCs) is of interest in directing MSC behavior for tissue engineering applications. This study investigates strain-induced differentiation and proliferation of MSCs, and investigates t...

journal_title：Annals of biomedical engineering

authors： Kearney EM,Farrell E,Prendergast PJ,Campbell VA

更新日期：2010-05-01 00:00:00

abstract：:Conventional nanoporous hydrogels often lead to slow cartilage deposition by MSCs in 3D due to physical constraints and requirement for degradation. Our group has recently reported macroporous gelatin microribbon (μRB) hydrogels, which substantially accelerate MSC-based cartilage formation in vitro compared to convent...

journal_title：Annals of biomedical engineering

authors： Barati D,Gegg C,Yang F

更新日期：2020-07-01 00:00:00

abstract：:We present a method for the localized statistical discrimination of class populations based on the Karhunen-Loève and Fukunaga-Koontz transforms. These transforms provide features that model the variance of a sample distribution. The spatial series of a 196 channel epicardial electrogram recording from an arrythmogeni...

journal_title：Annals of biomedical engineering

authors： Ciaccio EJ,Dunn SM,Akay M,Wit AL,Coromilas J,Costeas CA

更新日期：1994-09-01 00:00:00

abstract：:An MR image-based computational model of a murine KHT sarcoma is presented that allows the calculation of plasma fluid and solute transport within tissue. Such image-based models of solid tumors may be used to optimize patient-specific therapies. This model incorporates heterogeneous vasculature and tissue porosity to...

journal_title：Annals of biomedical engineering

authors： Pishko GL,Astary GW,Mareci TH,Sarntinoranont M

更新日期：2011-09-01 00:00:00

abstract：:Image registration and motion estimation play central roles in many fields, including RADAR, SONAR, light microscopy, and medical imaging. Because of its central significance, estimator accuracy, precision, and computational cost are of critical importance. We have previously presented a highly accurate, spline-based ...

journal_title：Annals of biomedical engineering

authors： Viola F,Coe RL,Owen K,Guenther DA,Walker WF

更新日期：2008-12-01 00:00:00

abstract：:The false vocal folds are believed to be components of the acoustic filter that is responsible for shaping the voice. However, the effects of false vocal folds on the vocal fold vibration and the glottal aerodynamic during phonation remain unclear. This effect has implications for computational modeling of phonation a...

journal_title：Annals of biomedical engineering

authors： Zheng X,Bielamowicz S,Luo H,Mittal R

更新日期：2009-03-01 00:00:00

abstract：:There are recent reports of hybrid tissue-fabric materials with good performance-high biocompatibility and high mechanical strength. In this study, we demonstrate the capability of a hybrid material as a long-term filter for blood proteins. Polyester fabrics were implanted into rats to fabricate hybrid tissue-fabric m...

journal_title：Annals of biomedical engineering

authors： Inoue Y,Yokota T,Sekitani T,Kaneko A,Woo T,Kobayashi S,Shibuya T,Tanaka M,Kosukegawa H,Saito I,Isoyama T,Abe Y,Yambe T,Someya T,Sekino M

更新日期：2017-05-01 00:00:00

abstract：:For several years, Virginia Tech and other schools have measured the frequency and severity of head impacts sustained by collegiate American football players in real time using the Head Impact Telemetry (HIT) System of helmet-mounted accelerometers. In this study, data from 37,128 head impacts collected at Virginia Te...

journal_title：Annals of biomedical engineering

authors： Funk JR,Rowson S,Daniel RW,Duma SM

更新日期：2012-01-01 00:00:00

abstract：:Understanding the complex spatiotemporal dynamics of action potential propagation in the heart during arrhythmia is exceedingly difficult. This study applies nonlinear dynamics tools to simplify this task. Using the results of a simulation of an electrical induction of reentry in a sheet of myocardium represented as a...

journal_title：Annals of biomedical engineering

authors： Larson C,Dragnev L,Trayanova N

更新日期：2003-07-01 00:00:00

abstract：:This paper presents an in vitro temperature mapping study of bovine cardiac tissue during radiofrequency ablation. The objectives were to: (i) develop a technique for measuring the spatial and temporal temperature distribution in the tissue and in the blood during ablation, and (ii) use the temperature measurements to...

journal_title：Annals of biomedical engineering

authors： Jain MK,Wolf PD

更新日期：2000-09-01 00:00:00

abstract：:The statistical distribution of von Mises stress in the trabeculae of human vertebral cancellous bone was estimated using large-scale finite element models. The goal was to test the hypothesis that average trabecular von Mises stress is correlated to the maximum trabecular level von Mises stress. The hypothesis was pr...

journal_title：Annals of biomedical engineering

authors： Fyhrie DP,Hoshaw SJ,Hamid MS,Hou FJ

更新日期：2000-01-01 00:00:00

abstract：:Intracellular calcium concentration and transmembrane potentials are two important measurements used to study the mechanisms of cardiac activity. Fluorescent dyes have been used to measure these separately but not simultaneously in cardiac tissue. Fluo-3 and Fluo-4 (a recently improved version of Fluo-3) have been use...

journal_title：Annals of biomedical engineering

authors： Johnson PL,Smith W,Baynham TC,Knisley SB

更新日期：1999-07-01 00:00:00

abstract：:A rigorous analysis of blood flow must be based on the branching pattern and vascular geometry of the full vascular circuit of interest. It is experimentally difficult to reconstruct the entire vascular circuit of any organ because of the enormity of the vessels. The objective of the present study was to develop a nov...

journal_title：Annals of biomedical engineering

authors： Mittal N,Zhou Y,Ung S,Linares C,Molloi S,Kassab GS

更新日期：2005-08-01 00:00:00

abstract：:To study the effects of smooth muscle contraction and relaxation on the strain and stress distribution in the vascular wall, a mathematical model was proposed. The artery was assumed to be a thick-walled orthotropic tube made of nonlinear, incompressible elastic material. Considering that the contraction of smooth mus...

journal_title：Annals of biomedical engineering

authors： Rachev A,Hayashi K

更新日期：1999-07-01 00:00:00

abstract：:Typical inverse dynamics approaches to the calculation of muscle, ligament, and joint contact forces are based on a step-wise solution of the equations of motion. This approach is therefore limited in its ability to provide insight as to the muscular, ligamentous, and articular interactions that create joint stability...

journal_title：Annals of biomedical engineering

authors： Cleather DJ,Bull AM

更新日期：2011-07-01 00:00:00

abstract：:The applicability of a computer model, which relates the transmural mechanical distribution in the left ventricle (LV) to its global function at different loading conditions, was evaluated in patients with normal to near normal LV function undergoing cardiac catheterization. Left ventriculography and measurements of a...

journal_title：Annals of biomedical engineering

authors： Abboud L,Beyar R,Battler A,Rat M,Cohen A,Sideman S

更新日期：1990-01-01 00:00:00

abstract：:A major tissue engineering challenge is the creation of multilaminate scaffolds with layer-specific mechanical properties representative of native tissues, such as heart valve leaflets, blood vessels, and cartilage. For this purpose, poly(ethylene glycol) diacrylate (PEGDA) hydrogels are attractive materials due to th...

journal_title：Annals of biomedical engineering

authors： Tseng H,Cuchiara ML,Durst CA,Cuchiara MP,Lin CJ,West JL,Grande-Allen KJ

更新日期：2013-02-01 00:00:00

abstract：:Congenital heart disease is the leading cause of infant death in the United States with over 36,000 newborns affected each year. Despite this growing problem there are few mechanical circulatory support devices designed specifically for pediatric and neonate patients. Previous research has been done investigating pedi...

journal_title：Annals of biomedical engineering

authors： Good BC,Deutsch S,Manning KB

更新日期：2016-04-01 00:00:00

abstract：:It is proposed that the maximum in cuff pressure oscillations during oscillometry is due to the buckling of the brachial artery under a cuff. This theory is investigated by means of a mathematical model of oscillatometry that includes the mechanics of the occlusive arm cuff, the arterial pressure pulse waveform, and t...

journal_title：Annals of biomedical engineering

authors： Drzewiecki G,Hood R,Apple H

更新日期：1994-01-01 00:00:00

abstract：:Intramuscular pressure (IMP), defined as skeletal muscle interstitial fluid pressure, reflects changes in individual muscle tension and may provide crucial insight into musculoskeletal biomechanics and pathologies. IMP may be measured using fiber-optic fluid pressure sensors, provided the sensor is adequately anchored...

journal_title：Annals of biomedical engineering

authors： Go SA,Jensen ER,O'Connor SM,Evertz LQ,Morrow DA,Ward SR,Lieber RL,Kaufman KR

更新日期：2017-03-01 00:00:00

abstract：:We have studied the interaction of high frequency jet ventilation with cardiovascular pressures and flows. Results in dogs show that the amplitude of all intrathoracic pressures and flows fluctuate with a frequency equal to the difference between the heart rate and ventilator rate. The magnitude of this amplitude vari...

journal_title：Annals of biomedical engineering

authors： Mitzner W,Gioia F,Weinmann GG,Robotham JL,Ehrlich W

更新日期：1987-01-01 00:00:00