Abstract:
:We have studied the interaction of high frequency jet ventilation with cardiovascular pressures and flows. Results in dogs show that the amplitude of all intrathoracic pressures and flows fluctuate with a frequency equal to the difference between the heart rate and ventilator rate. The magnitude of this amplitude variation may be sufficient to obliterate periodically the pulsations in pulmonary artery and right atrial pressures. It is also shown that these cardiovascular beats can occur when the ventilator rate is close to integral multiples of the heart rate. Direct measurement of pleural pressure and the observation that the beats are markedly reduced when the chest is open support the hypothesis that the primary mechanism responsible for these beats is the interaction of the respiratory fluctuations in pleural pressure with the cardiac-generated pressure pulsations.
journal_name
Ann Biomed Engjournal_title
Annals of biomedical engineeringauthors
Mitzner W,Gioia F,Weinmann GG,Robotham JL,Ehrlich Wdoi
10.1007/BF02584287subject
Has Abstractpub_date
1987-01-01 00:00:00pages
319-29issue
3-4eissn
0090-6964issn
1573-9686journal_volume
15pub_type
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