Abstract：
:The effects of tissue hydration and fixed charge density on hydraulic permeability and creep behavior of cartilaginous tissues have been investigated using the triphasic theory and finite element methods. The empirical model for hydraulic permeability of uncharged gels and Mackie and Meares (1955) model for ion diffusivity were used in the numerical analysis. The hydraulic permeabilities of normal and trypsin-treated porcine annulus fibrosus tissues were measured indirectly. Analysis of the experimental data from this study and in literature indicates that the water content plays a more important role in regulating tissue permeability than fixed charge density for normal tissues. A change in glycosaminoglycan content will change both triphasic closed-circuit (or intrinsic) and biphasic open-circuit permeabilities of cartilaginous tissues. Analysis also shows that both fixed charge density and water content play an important role in tissue creep response. This study adds new knowledge to the permeability and creep behavior of cartilaginous tissues and is important for understanding the nutrition in intervertebral disk.
journal_name
Ann Biomed Engjournal_title
Annals of biomedical engineeringauthors
Gu WY,Yao Hdoi
10.1114/1.1615576subject
Has Abstractpub_date
2003-11-01 00:00:00pages
1162-70issue
10eissn
0090-6964issn
1573-9686journal_volume
31pub_type
杂志文章abstract：:Although it is known that long cortical bone structurally alter their area moment of inertia with age related bone loss maintaining their bending strength, the incidence of fragility fractures associated with cortical thinning still prevails. We hypothesize that cortical thinning with aging increases the local bucklin...
journal_title：Annals of biomedical engineering
pub_type： 杂志文章
doi：10.1007/s10439-009-9751-9
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abstract：:Currently, there are no clinically available tools or applications which could predict osteoarthritis development. Some computational models have been presented to simulate cartilage degeneration, but they are not clinically feasible due to time required to build subject-specific knee models. Therefore, the objective ...
journal_title：Annals of biomedical engineering
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abstract：:Cardiac MRI (CMR) techniques offer non-invasive visualizations of cardiac morphology and function. However, imaging can be time-consuming and complex. Seismocardiography (SCG) measures physical vibrations transmitted through the chest from the beating heart and pulsatile blood flow. SCG signals can be acquired quickly...
journal_title：Annals of biomedical engineering
pub_type： 杂志文章
doi：10.1007/s10439-020-02491-3
更新日期：2020-06-01 00:00:00
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journal_title：Annals of biomedical engineering
pub_type： 杂志文章
doi：10.1114/1.1430749
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journal_title：Annals of biomedical engineering
pub_type： 临床试验,杂志文章
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更新日期：2017-09-01 00:00:00
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journal_title：Annals of biomedical engineering
pub_type： 杂志文章
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journal_title：Annals of biomedical engineering
pub_type： 杂志文章
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journal_title：Annals of biomedical engineering
pub_type： 杂志文章
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更新日期：2014-05-01 00:00:00
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pub_type： 杂志文章
doi：10.1023/b:abme.0000030759.80354.e8
更新日期：2004-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2011-11-01 00:00:00
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journal_title：Annals of biomedical engineering
pub_type： 杂志文章
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journal_title：Annals of biomedical engineering
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更新日期：2004-01-01 00:00:00
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journal_title：Annals of biomedical engineering
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journal_title：Annals of biomedical engineering
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journal_title：Annals of biomedical engineering
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journal_title：Annals of biomedical engineering
pub_type： 杂志文章,评审
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更新日期：2012-01-01 00:00:00
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journal_title：Annals of biomedical engineering
pub_type： 杂志文章
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journal_title：Annals of biomedical engineering
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journal_title：Annals of biomedical engineering
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journal_title：Annals of biomedical engineering
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更新日期：2004-03-01 00:00:00
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journal_title：Annals of biomedical engineering
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journal_title：Annals of biomedical engineering
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journal_title：Annals of biomedical engineering
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journal_title：Annals of biomedical engineering
pub_type： 杂志文章
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journal_title：Annals of biomedical engineering
pub_type： 杂志文章
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pub_type： 杂志文章
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