Abstract:
:Based on mathematical expressions governing the electric field, the extracellular potentials generated by a single active fiber in a restricted circular cylindrical volume conductor are evaluated. This paper examines the effect of the extent of the volume conductor, with radius b, on the extracellular potentials at different field points. For values of b less than 1.5 times the fiber radius, the extracellular potentials in the volume conductor are always the core conductor potentials, independent of the shape and amplitude of the transmembrane potential. For b greater than a critical radius (a value that depends on the transmembrane potential waveform), the extracellular potentials at and near the membrane are the same as if the volume conductor were unbounded. Near the boundary with the insulator, the amplitude of the extracellular potentials is equal to the core conductor amplitude, although the potentials are much broader than the core conductor potential.
journal_name
Ann Biomed Engjournal_title
Annals of biomedical engineeringauthors
Trayanova N,Henriquez CS,Plonsey Rdoi
10.1007/BF02368439subject
Has Abstractpub_date
1990-01-01 00:00:00pages
219-38issue
3eissn
0090-6964issn
1573-9686journal_volume
18pub_type
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