A review of return to play issues and sports-related concussion.


:Mild traumatic brain injury in sports has become a significant public health concern which has not only received the general public's attention through multiple news media stories involving athletic concussions, but has also resulted in local, state, and national legislative efforts to improve recognition and management. The purpose of this article is to review the current literature for return to play (RTP) guidelines. State, regional, national, and professional legislation on sport-related concussion RTP management issues will be reviewed. This article will be helpful in developing a generalized systematic approach to concussion management and highlight specific RTP guidelines. The article will also touch upon specific contraindications to RTP, the role of neuropsychological testing in RTP, and other considerations and complications that affect an athlete's ability to return to competition. Finally, considerations for terminating an athlete's competitive season or ending a career after sustaining a concussion resulting in prolonged and protracted symptomatology or repeated concussions will be reviewed. PubMed and Google were searched using the key terms mentioned below. In addition, the author's library of concussion-related articles was reviewed for the relevant literature.


Ann Biomed Eng


Doolan AW,Day DD,Maerlender AC,Goforth M,Gunnar Brolinson P




Has Abstract


2012-01-01 00:00:00












  • A mediated glucose biosensor incorporated with reverse iontophoresis function for noninvasive glucose monitoring.

    abstract::The objective of this study was to develop a ferrocene mediated glucose biosensor for reverse iontophoresis. An amperometric ferrocene mediated glucose biosensor based on a three electrodes planar configuration was constructed using screen printing technique. Different combinations of glucose oxidase and ferrocene loa...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Ching CT,Sun TP,Huang SH,Shieh HL,Chen CY

    更新日期:2010-04-01 00:00:00

  • Customised Selection of the Haptic Design in C-Loop Intraocular Lenses Based on Deep Learning.

    abstract::In order to increase the probability of having a successful cataract post-surgery, the customisation of the haptic design of the intraocular lens (IOL) according to the characteristics of the patient is recommended. In this study, we present two prediction models based on deep neural networks (DNNs). One is capable of...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Cabeza-Gil I,Ríos-Ruiz I,Calvo B

    更新日期:2020-12-01 00:00:00

  • Thermal analysis of the bone surface induced by laser radiation.

    abstract::High energy laser has emerged to be an important surgical tool in medical technology. However, the application of laser energy to drill or cut a bone is still in an experimental state. In order to estimate the adequacy of laser heating of bone surface and at the same time minimize the damage to the bone tissue, we dev...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Chen II,Saha S

    更新日期:1987-01-01 00:00:00

  • Two methods for recommending bat weights.

    abstract::Baseball players swung very light and very heavy bats through our instrument and the speed of the bat was recorded. These data were used to make mathematical models for each person. Then these models were coupled with equations of physics for bat-ball collisions to compute the Ideal Bat Weight for each individual. How...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Bahill AT,Freitas MM

    更新日期:1995-07-01 00:00:00

  • Effects of crowding on the thermal stability of heterogeneous protein solutions.

    abstract::Crowding can substantially affect the transition of a protein between its native (N) and unfolded (U) states via volume exclusion effects. Also, it influences considerably the aggregation (A) of unfolded proteins. To examine the details, we developed an approach for computing the kinetic rates of the process N <--> U ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Despa F,Orgill DP,Lee RC

    更新日期:2005-08-01 00:00:00

  • Numerical simulation of cell motion in tube flow.

    abstract::A theoretical model is presented for describing the motion of a deformable cell encapsulating a Newtonian fluid and enclosed by an elastic membrane in tube flow. In the mathematical formulation, the interior and exterior hydrodynamics are coupled with the membrane mechanics by means of surface equilibrium equations, a...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Pozrikidis C

    更新日期:2005-02-01 00:00:00

  • Quantification of rigidity in Parkinson's disease.

    abstract::In this paper, a new method for quantification of rigidity in elbow joint of Parkinsonian patients is introduced. One of the most known syndromes in Parkinson's disease (PD) is increased passive stiffness in muscles, which leads to rigidity in joints. Clinical evaluation of stiffness in wrist and/or elbow, commonly us...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Sepehri B,Esteki A,Ebrahimi-Takamjani E,Shahidi GA,Khamseh F,Moinodin M

    更新日期:2007-12-01 00:00:00

  • Fluid shifts due to microgravity and their effects on bone: a review of current knowledge.

    abstract::Bone loss during long-term space flight is potentially a significant problem. Bone mineral density measurements show that bone is lost at a rate of about 1% per month from the lumbar spine, and 1.5% per month from the hip. Bone density changes are not uniform throughout the skeleton, and there is accumulating evidence...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章,评审


    authors: McCarthy ID

    更新日期:2005-01-01 00:00:00

  • Human saphenous vein coronary artery bypass graft morphology, geometry and hemodynamics.

    abstract::Coronary artery bypass graft (CABG) failure has been linked to graft hemodynamics, in particular wall shear stress. This study characterizes the morphology, geometry and wall shear stress patterns in human CABGs. The intimal thickness (IT) in 49 human saphenous vein CABGs was measured by digital light microscopy. The ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Leask RL,Butany J,Johnston KW,Ethier CR,Ojha M

    更新日期:2005-03-01 00:00:00

  • Human lumbar spine creep during cyclic and static flexion: creep rate, biomechanics, and facet joint capsule strain.

    abstract::There is a high incidence of low back pain (LBP) associated with occupations requiring sustained and/or repetitive lumbar flexion (SLF and RLF, respectively), which cause creep of the viscoelastic tissues. The purpose of this study was to determine the effect of creep on lumbar biomechanics and facet joint capsule (FJ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Little JS,Khalsa PS

    更新日期:2005-03-01 00:00:00

  • A review of approaches to mobility telemonitoring of the elderly in their living environment.

    abstract::Rapid technological advances have prompted the development of a wide range of telemonitoring systems to enable the prevention, early diagnosis and management, of chronic conditions. Remote monitoring can reduce the amount of recurring admissions to hospital, facilitate more efficient clinical visits with objective res...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章,评审


    authors: Ní Scanaill C,Carew S,Barralon P,Noury N,Lyons D,Lyons GM

    更新日期:2006-04-01 00:00:00

  • Automatic Detection of Contracting Muscle Regions via the Deformation Field of Transverse Ultrasound Images: A Feasibility Study.

    abstract::Accurate identification of contracting muscles can help us to understand the muscle function in both physiological and pathological conditions. Conventional electromyography (EMG) have limited access to deep muscles, crosstalk, or instability in the recordings. Accordingly, a novel framework was developed to detect co...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Zheng Y,Shin H,Kamper DG,Hu X

    更新日期:2021-01-01 00:00:00

  • Myofiber ellipticity as an explanation for transverse asymmetry of skeletal muscle diffusion MRI in vivo signal.

    abstract::Due to its unique non-invasive microstructure probing capabilities, diffusion tensor imaging (DTI) constitutes a valuable tool in the study of fiber orientation in skeletal muscles. By implementing a DTI sequence with judiciously chosen directional encoding to quantify in vivo the microarchitectural properties in the ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Karampinos DC,King KF,Sutton BP,Georgiadis JG

    更新日期:2009-12-01 00:00:00

  • Coupling of a 3D finite element model of cardiac ventricular mechanics to lumped systems models of the systemic and pulmonic circulation.

    abstract::In this study we present a novel, robust method to couple finite element (FE) models of cardiac mechanics to systems models of the circulation (CIRC), independent of cardiac phase. For each time step through a cardiac cycle, left and right ventricular pressures were calculated using ventricular compliances from the FE...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Kerckhoffs RC,Neal ML,Gu Q,Bassingthwaighte JB,Omens JH,McCulloch AD

    更新日期:2007-01-01 00:00:00

  • Computational study of proteolysis-driven single cell migration in a three-dimensional matrix.

    abstract::Cell migration is a fundamental process that is crucial to a variety of physiological events. While traditional approaches have focused on two-dimensional (2D) systems, recent efforts have shifted to studying migration in three-dimensional (3D) matrices. A major distinction that has emerged is the increased importance...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Harjanto D,Zaman MH

    更新日期:2010-05-01 00:00:00

  • Computational study of fluid mechanical disturbance induced by endovascular stents.

    abstract::Arterial restenosis following stent deployment may be influenced by the local flow environment within and around the stent. We have used computational fluid dynamics to investigate the flow field in the vicinity of model stents positioned within straight and curved vessels. Our simulations have revealed the presence o...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Seo T,Schachter LG,Barakat AI

    更新日期:2005-04-01 00:00:00

  • Vortex ring formation in the left ventricle of the heart: analysis by 4D flow MRI and Lagrangian coherent structures.

    abstract::Recent studies suggest that vortex ring formation during left ventricular (LV) rapid filling is an optimized mechanism for blood transport, and that the volume of the vortex ring is an important measure. However, due to lack of quantitative methods, the volume of the vortex ring has not previously been studied. Lagran...

    journal_title:Annals of biomedical engineering

    pub_type: 临床试验,杂志文章


    authors: Töger J,Kanski M,Carlsson M,Kovács SJ,Söderlind G,Arheden H,Heiberg E

    更新日期:2012-12-01 00:00:00

  • Development of FRET assay into quantitative and high-throughput screening technology platforms for protein-protein interactions.

    abstract::Förster resonance energy transfer (FRET) technology has been widely used in biological and biomedical research and is a very powerful tool in elucidating protein interactions in many cellular processes. Ubiquitination and SUMOylation are multi-step cascade reactions, involving multiple enzymes and protein-protein inte...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Song Y,Madahar V,Liao J

    更新日期:2011-04-01 00:00:00

  • Mechanical behavior of vascular smooth muscle in cylindrical segments of arteries in vitro.

    abstract::Vascular smooth muscle mechanics have been studied in vitro in cylindrical segments of dog carotid artery, human internal mammary artery, and human saphenous vein. Such cylindrical preparations maintain normal vessel geometry and also permit correlation of mechanical phenomena with transmural pressure. These studies s...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Dobrin PB

    更新日期:1984-01-01 00:00:00

  • Surfactant properties differentially influence intravascular gas embolism mechanics.

    abstract::Gas bubble motion in a blood vessel causes temporal and spatial gradients of shear stress at the cell surface lining the vessel wall as the bubble approaches the cell, moves over it and passes it by. Rapid reversals occur in the sign of the shear stress imparted to the cell surface during this motion. These may result...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Swaminathan TN,Ayyaswamy PS,Eckmann DM

    更新日期:2010-12-01 00:00:00

  • Rat aortic smooth muscle cells contract in response to serum and its components in a calcium independent manner.

    abstract::Diluted serum provides a model of interstitial fluid that can be used to study the response of smooth muscle cells (SMCs) to interstitial flow. The effect of serum and some of its components on SMC contraction (area reduction) and intracellular calcium ([Ca2+]i) response were characterized in rat aortic SMC in vitro. ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Ainslie K,Shi ZD,Garanich JS,Tarbell JM

    更新日期:2004-12-01 00:00:00

  • Motile Dendritic Cells Sense and Respond to Substrate Geometry.

    abstract::Dendritic cell (DC) migration is required for efficient presentation of antigen to T cells and the initiation of an adaptive immune response. In spite of its importance, many aspects of DC migration have not been characterized. DCs encounter a variety of environments with different stiffness and geometry, but the effe...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Bendell AC,Anderson N,Blumenthal D,Williamson EK,Chen CS,Burkhardt JK,Hammer DA

    更新日期:2018-09-01 00:00:00

  • Historic and future development of high-frequency ventilation.

    abstract::High-frequency ventilation (HFV) has not one but several histories. Proceeding along largely independent pathways are techniques using frequencies of 1-5 Hz and techniques using 10-40 Hz, the former being introduced by Sjostrand in 1971, the latter by Lunkenheimer in 1972. It was nearly ten years before it was recogni...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Bryan AC

    更新日期:1984-01-01 00:00:00

  • Reinforcement of Mono- and Bi-layer Poly(Ethylene Glycol) Hydrogels with a Fibrous Collagen Scaffold.

    abstract::Biomaterial-based tissue engineering strategies hold great promise for osteochondral tissue repair. Yet significant challenges remain in joining highly dissimilar materials to achieve a biomimetic, mechanically robust design for repairing interfaces between soft tissue and bone. This study sought to improve interfacia...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Kinneberg KR,Nelson A,Stender ME,Aziz AH,Mozdzen LC,Harley BA,Bryant SJ,Ferguson VL

    更新日期:2015-11-01 00:00:00

  • Biomechanical Properties and Microstructure of Heart Chambers: A Paired Comparison Study in an Ovine Model.

    abstract::Mechanical properties of the cardiac tissue play an important role in normal heart function. The goal of this study was to determine the passive mechanical properties of all heart chambers through a paired comparison study in an ovine model. Ovine heart was used due its physiological and anatomical similarities to hum...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Javani S,Gordon M,Azadani AN

    更新日期:2016-11-01 00:00:00

  • Generalized sensitivity functions in physiological system identification.

    abstract::Parameters of physiological models are commonly associated in an input-output experiment with a specific pattern of the system response. This association is often made on an intuitive basis by traditional sensitivity analysis, i.e., by inspecting the variations of model output trajectories with respect to parameter va...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Thomaseth K,Cobelli C

    更新日期:1999-09-01 00:00:00

  • Recurrent wavefront morphologies: a method for quantifying the complexity of epicardial activation patterns.

    abstract::We have developed a method for quantifying the complexity of activation patterns observed during ventricular fibrillation (VF) that is based on our previously reported methodology for decomposing epicardial mapping data into a set of isolated wavefronts. One-half second datasets are acquired from a 21 x 24 array of un...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Rogers JM,Usui M,KenKnight BH,Ideker RE,Smith WM

    更新日期:1997-09-01 00:00:00

  • Body Anthropometry and Bone Strength Conjointly Determine the Risk of Hip Fracture in a Sideways Fall.

    abstract::We hypothesize that variations of body anthropometry, conjointly with the bone strength, determine the risk of hip fracture. To test the hypothesis, we compared, in a simulated sideways fall, the hip impact energy to the energy needed to fracture the femur. Ten femurs from elderly donors were tested using a novel drop...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Palanca M,Perilli E,Martelli S

    更新日期:2020-11-12 00:00:00

  • High-resolution 3D ultrasound jawbone surface imaging for diagnosis of periodontal bony defects: an in vitro study.

    abstract::Although medical specialties have recognized the importance of using ultrasonic imaging, dentistry is only beginning to discover its benefit. This has particularly been important in the field of periodontics which studies infections in the gum and bone tissues that surround the teeth. This study investigates the feasi...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Mahmoud AM,Ngan P,Crout R,Mukdadi OM

    更新日期:2010-11-01 00:00:00

  • The Impact of Anti-tumor Agents on ER-Positive MCF-7 and HER2-Positive SKBR-3 Breast Cancer Cells Biomechanics.

    abstract::Studying human cancer from a biomechanical perspective may contribute to pathogenesis understanding which leads to the malignancy. In this study, biomechanics of suspended and adhered breast cancer cells were investigated via the micropipette aspiration method with special emphasis on comparing the cell stiffness and ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章


    authors: Metsiou DN,Siatis KE,Giannopoulou E,Papachristou DJ,Kalofonos HP,Koutras A,Athanassiou G

    更新日期:2019-08-01 00:00:00