Bimodal analysis of mammary epithelial cell migration in two dimensions.

abstract：:Experimental studies have shown that cardiac fibroblasts are electrically inexcitable, but can contribute to electrophysiology of myocardium in various manners. The aim of this computational study was to give insights in the electrophysiological role of fibroblasts and their interaction with myocytes. We developed a m...

journal_title：Annals of biomedical engineering

authors： Sachse FB,Moreno AP,Abildskov JA

更新日期：2008-01-01 00:00:00

abstract：:In this paper, an intelligent proportional-integral-derivative (PID) control method is introduced to the robotic testing system for the biomechanical study of human musculoskeletal joints. For the testing system, the robot is a highly nonlinear and heavily coupled complicated system, and the human spinal specimen also...

journal_title：Annals of biomedical engineering

authors： Tian L

更新日期：2004-06-01 00:00:00

abstract：:Dual X-ray absorptiometry (DXA) measures areal bone mineral density (aBMD) by simplifying a complex 3D bone structure to a 2D projection and is not equally effective for explaining fracture strength in women and men. Unlike DXA, subject-specific quantitative computed tomography-based finite element analysis (QCT/FEA) ...

journal_title：Annals of biomedical engineering

authors： Rezaei A,Giambini H,Rossman T,Carlson KD,Yaszemski MJ,Lu L,Dragomir-Daescu D

更新日期：2017-12-01 00:00:00

abstract：:Registration of bone structures is a common problem in medical research as well as in clinical applications. Intrasubject rigid 3D monomodality registration of segmented bone structures of CT images and multimodality registration of muMR and segmented muCT bone images were performed with the multiresolution intensity-...

journal_title：Annals of biomedical engineering

authors： Museyko O,Eisa F,Hess A,Schett G,Kalender WA,Engelke K

更新日期：2010-07-01 00:00:00

abstract：:We propose a new method for guiding catheter ablation procedures to abolish sites of origin of arrhythmias. This method models both cardiac electrical activity and current pulses delivered from the tip of the ablation catheter with a single equivalent moving dipole (SEMD). The SEMD parameters are obtained from analysi...

journal_title：Annals of biomedical engineering

authors： Armoundas AA,Feldman AB,Mukkamala R,Cohen RJ

更新日期：2003-05-01 00:00:00

abstract：:It would often be desirable to obtain the respiratory rate during everyday conditions without obtaining an additional respiratory trace. This study investigates the agreement between respiratory rate assessed from the electrocardiogram (ECG) and the reference respiratory rate derived from a nasal/oral airflow (AF). Na...

journal_title：Annals of biomedical engineering

authors： Cysarz D,Zerm R,Bettermann H,Frühwirth M,Moser M,Kröz M

更新日期：2008-12-01 00:00:00

abstract：:Phenotype transformation of vascular smooth muscle cells (VSMCs) has been reported to be directly influenced by the frequency of mechanical strain. This study explored the effects of different frequencies of mechanical strain on expression of phenotype marker h1-calponin and the possible mechanism. VSMCs were subjecte...

journal_title：Annals of biomedical engineering

authors： Qu MJ,Liu B,Qi YX,Jiang ZL

更新日期：2008-09-01 00:00:00

abstract：:The planar fibrous connective tissues of the body are composed of a dense extracellular network of collagen and elastin fibers embedded in a ground matrix, and thus can be thought of as biocomposites. Thus, the quantification of fiber architecture is an important step in developing an understanding of the mechanics of...

journal_title：Annals of biomedical engineering

authors： Sacks MS,Smith DB,Hiester ED

更新日期：1997-07-01 00:00:00

abstract：:Cerebral blood flow (CBF) increases as arterial oxygen content falls with hypoxic (low PO2), anemic (low hemoglobin) and carbon monoxide (CO) (high carboxyhemoglobin) hypoxia. Despite a higher arterial PO2, CO hypoxia provokes a greater increase in CBF than hypoxic hypoxia. We analyzed published data using a compartme...

journal_title：Annals of biomedical engineering

authors： Sharan M,Popel AS,Hudak ML,Koehler RC,Traystman RJ,Jones MD Jr

更新日期：1998-01-01 00:00:00

abstract：:Experimental and diagnostic procedures like distension of a balloon catheter, bougie, and esophagogastroduodenoscopy can induce shear deformation in the esophageal wall. However, the shear modulus of the esophagus is yet unknown. The aim of this study was to determine the esophageal shear modulus and its dependence on...

journal_title：Annals of biomedical engineering

authors： Yang J,Liao D,Zhao J,Gregersen H

更新日期：2004-09-01 00:00:00

abstract：:This paper outlines a comprehensive parametric approach for quantifying mechanical properties of spatially heterogeneous thin biological specimens such as human breast tissue using contact-mode Atomic Force Microscopy. Using inverse finite element (FE) analysis of spherical nanoindentation, the force response from hyp...

journal_title：Annals of biomedical engineering

authors： Roy R,Desai JP

更新日期：2014-09-01 00:00:00

abstract：:Thorax injuries mainly due to rib fractures have been associated with high rates of morbidity and mortality in motor vehicle crashes. Thoracic biomechanics has been studied extensively, but there are no robust biomechanical response targets for ribs that consider age, sex, body size, and vulnerability factors. The obj...

journal_title：Annals of biomedical engineering

authors： Kang YS,Kwon HJ,Stammen J,Moorhouse K,Agnew AM

更新日期：2021-02-01 00:00:00

abstract：:Arterial responses to diverse pathologies and insults likely occur via similar mechanisms. For example, many studies suggest that the natural process of aging and isolated systolic hypertension share many characteristics in arteries, including loss of functional elastin, decreased smooth muscle tone, and altered rates...

journal_title：Annals of biomedical engineering

authors： Valentín A,Humphrey JD,Holzapfel GA

更新日期：2011-07-01 00:00:00

abstract：:High-frequency ventilation (HFV) has not one but several histories. Proceeding along largely independent pathways are techniques using frequencies of 1-5 Hz and techniques using 10-40 Hz, the former being introduced by Sjostrand in 1971, the latter by Lunkenheimer in 1972. It was nearly ten years before it was recogni...

journal_title：Annals of biomedical engineering

authors： Bryan AC

更新日期：1984-01-01 00:00:00

abstract：:A mathematical model of heat, water and soluble gas exchange in the airways and alveoli was used to predict the location of soluble gas exchange in the lung. A previously published model of heat, water and soluble gas exchange in the airways was improved by incorporating anatomical data on the airway wall to better de...

journal_title：Annals of biomedical engineering

authors： Anderson JC,Babb AL,Hlastala MP

更新日期：2003-12-01 00:00:00

abstract：:Impedance data, e.g., system responses, from perturbing small amplitude applied sinusoid signals of near DC to high kilohertz frequencies, give chemical information. Analysis of frequency-dependent imaginary and real impedance proceeds from equivalent analog circuit elements to chemical and physical significance deter...

journal_title：Annals of biomedical engineering

authors： Buck RP

更新日期：1992-01-01 00:00:00

abstract：:Quantitative analysis of breast morphometry is critical to breast plastic surgery. Recently, three-dimensional (3D) photography has emerged as a strong new alternative for breast morphometry analysis in comparison to other existing techniques. 3D photography enables the capture of the entire breast surface topology vi...

journal_title：Annals of biomedical engineering

authors： Chen D,Chittajallu DR,Passalis G,Kakadiaris IA

更新日期：2010-05-01 00:00:00

abstract：:Knowledge of strain-rate sensitivity of soft tissue viscoelastic and nonlinear elastic properties is important for accurate predictions of biomechanical behavior and for quantitative assessment of the effects of disease or surgical/pharmaceutical intervention. Soft tissues are known to exhibit mild rate sensitivity, b...

journal_title：Annals of biomedical engineering

authors： Doehring TC,Carew EO,Vesely I

更新日期：2004-02-01 00:00:00

abstract：:Recent developments in computational modeling of cochlear implantation are promising to study in silico the performance of the implant before surgery. However, creating a complete computational model of the patient's anatomy while including an external device geometry remains challenging. To address such a challenge, ...

journal_title：Annals of biomedical engineering

authors： Mangado N,Ceresa M,Duchateau N,Kjer HM,Vera S,Dejea Velardo H,Mistrik P,Paulsen RR,Fagertun J,Noailly J,Piella G,González Ballester MÁ

更新日期：2016-08-01 00:00:00

abstract：:Glaucoma is a common optic neuropathy characterized by retinal ganglion cell death. Elevated intraocular pressure (IOP), a key risk factor for glaucoma, leads to significant biomechanical deformation of optic nerve head (ONH) cells and tissues. ONH astrocytes respond to this deformation by transforming to a reactive, ...

journal_title：Annals of biomedical engineering

authors： Mulvihill JJE,Raykin J,Snider EJ,Schildmeyer LA,Zaman I,Platt MO,Kelly DJ,Ethier CR

更新日期：2018-02-01 00:00:00

abstract：:Deep tissue injury (DTI) is a type of pressure ulcer in which tissue breakdown initiates at the bone-muscle interface under intact skin. Excessive deformation in the soft tissue, particularly around bony prominences, is believed to be one of the causes leading to the development of DTI. The main goal of this study was...

journal_title：Annals of biomedical engineering

authors： Solis LR,Liggins AB,Seres P,Uwiera RR,Poppe NR,Pehowich E,Thompson RB,Mushahwar VK

更新日期：2012-08-01 00:00:00

abstract：:Fingertips wrinkle due to long exposure to water. The biological reason for this morphological change is unclear and still not fully understood. There are two main hypotheses for the underlying mechanism of fingertip wrinkling: the 'shrink' model (in which the wrinkling is driven by the contraction of the lower layers...

journal_title：Annals of biomedical engineering

authors： Sáez P,Zöllner AM

更新日期：2017-04-01 00:00:00

abstract：:The nonlinear diffusion-reaction equations describing the nonequilibrium transport of CO2 through flat layers of complex but homogeneous aqueous media were solved by an approximate analytical method called the "Combined Damköhler Number" (CDN) technique. Unlike other approximate analytical solutions, the CDN technique...

journal_title：Annals of biomedical engineering

authors： Hoofd LJ,Tong RR,Stroeve P

更新日期：1986-01-01 00:00:00

abstract：:A progressive reduction in muscle fiber conduction velocity is typically observed during fatiguing muscle contraction. Although the exact causes of the conduction velocity decrease have not yet been fully established, increasing evidence suggests that changes in extracellular potassium concentration may be largely res...

journal_title：Annals of biomedical engineering

authors： Fortune E,Lowery MM

更新日期：2009-10-01 00:00:00

abstract：:Biologically active heart valves (tissue engineered and recellularized tissue-derived heart valves) have the potential to offer enhanced function when compared to current replacement value therapies since they can possibly remodel, and grow to meet the needs of the patient, and not require chronic medication. However,...

journal_title：Annals of biomedical engineering

authors： Hildebrand DK,Wu ZJ,Mayer JE Jr,Sacks MS

更新日期：2004-08-01 00:00:00

abstract：:The nonlinear dynamic properties of action potential encoding were studied in mechanosensory neurons innervating the slits of a slit-sense organ in the tropical wandering spider, Cupiennius salei. The organ contains two types of neurons that are morphologically similar but have different dynamic properties. Type A neu...

journal_title：Annals of biomedical engineering

authors： French AS,Sekizawa SI,Höger U,Torkkeli PH

更新日期：2001-03-01 00:00:00

abstract：:In this study, we have developed an integrated microfluidic platform for actively patterning mammalian cells, where poly(ethylene glycol) (PEG) hydrogels play two important roles as a non-fouling layer and a dielectric structure. The developed system has an embedded array of PEG microwells fabricated on a planar indiu...

journal_title：Annals of biomedical engineering

authors： Tsutsui H,Yu E,Marquina S,Valamehr B,Wong I,Wu H,Ho CM

更新日期：2010-12-01 00:00:00

abstract：:This article presents a multi-scale computational model describing the transport of water vapor and heat within the human conducting airways and its interaction with cellular fluid transport kinetics. This tight coupling between the cell and the evaporative flux allows the periciliary liquid (PCL) depth to be investig...

journal_title：Annals of biomedical engineering

authors： Warren NJ,Crampin EJ,Tawhai MH

更新日期：2010-12-01 00:00:00

abstract：:Despite the clinical effectiveness of coronary artery stenting, percutaneous coronary intervention or "stenting" is not free of complications. Stent malapposition (SM) is a common feature of "stenting" particularly in challenging anatomy, such as that characterized by long, tortuous and bifurcated segments. SM is an i...

journal_title：Annals of biomedical engineering

authors： Ragkousis GE,Curzen N,Bressloff NW

更新日期：2015-08-01 00:00:00

abstract：:Wall stress analysis of abdominal aortic aneurysm (AAA) is a promising method of identifying AAAs at high risk of rupture. However, neglecting residual strains (RS) in the load-free configuration of patient-specific finite element analysis models is a sever limitation that strongly affects the computed wall stresses. ...

journal_title：Annals of biomedical engineering

authors： Polzer S,Bursa J,Gasser TC,Staffa R,Vlachovsky R

更新日期：2013-07-01 00:00:00