Binary segmentation masks can improve intrasubject registration accuracy of bone structures in CT images.

abstract：:A major tissue engineering challenge is the creation of multilaminate scaffolds with layer-specific mechanical properties representative of native tissues, such as heart valve leaflets, blood vessels, and cartilage. For this purpose, poly(ethylene glycol) diacrylate (PEGDA) hydrogels are attractive materials due to th...

journal_title：Annals of biomedical engineering

authors： Tseng H,Cuchiara ML,Durst CA,Cuchiara MP,Lin CJ,West JL,Grande-Allen KJ

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:We present a fundamental theoretical framework for analysis of energy dissipation in any component of the circulatory system and formulate the full energy budget for both venous and arterial circulations. New indices allowing disease-specific subject-to-subject comparisons and disease-to-disease hemodynamic ...

journal_title：Annals of biomedical engineering

authors： Dasi LP,Pekkan K,de Zelicourt D,Sundareswaran KS,Krishnankutty R,Delnido PJ,Yoganathan AP

更新日期：2009-04-01 00:00:00

abstract：:We have developed a method for quantifying the complexity of activation patterns observed during ventricular fibrillation (VF) that is based on our previously reported methodology for decomposing epicardial mapping data into a set of isolated wavefronts. One-half second datasets are acquired from a 21 x 24 array of un...

journal_title：Annals of biomedical engineering

authors： Rogers JM,Usui M,KenKnight BH,Ideker RE,Smith WM

更新日期：1997-09-01 00:00:00

abstract：:Upon nerve injury, the body creates an environment consisting of permissive and non-permissive cues that instruct the function of cells involved in nerve repair. Among other roles, the developing extracellular matrix (ECM) acts as an underlying substrate to guide the union of neurites extending from the proximal stump...

journal_title：Annals of biomedical engineering

authors： Man AJ,Leach JK,Bannerman P

更新日期：2014-06-01 00:00:00

abstract：:"Smart" drug delivery systems should be selective and effective to ensure drug administration at the right time, at the right dosage, and anywhere in the body. Among the several administration routes and delivery systems that have been proposed, one of the most effective and promising is based on microfabricated parti...

journal_title：Annals of biomedical engineering

authors： Decuzzi P,Lee S,Decuzzi M,Ferrari M

更新日期：2004-06-01 00:00:00

abstract：:Osteoarthritis (OA) is a progressive, degenerative disease of articulating joints that not only affects the elderly, but also involves younger, more active individuals with prolonged participation in high physical-demand activities. Thus, effective therapies that are easy to adopt clinically are critical in limiting t...

journal_title：Annals of biomedical engineering

authors： Holyoak DT,Tian YF,van der Meulen MC,Singh A

更新日期：2016-06-01 00:00:00

abstract：:Platelet thrombosis under arterial conditions remains a large clinical problem. Previous in vitro experiments have concentrated on early adherence without thrombotic occlusion. We have developed a controllable hemodynamic system that creates intravascular thrombosis to occlusion. Lightly heparinized (3.5 USP units/mL)...

journal_title：Annals of biomedical engineering

authors： Para A,Bark D,Lin A,Ku D

更新日期：2011-07-01 00:00:00

abstract：:One of the major functions of the cardiovascular system is to deliver blood to the microcirculation where exchange of mass and energy can take place. In the present article, we will provide an overview of the state-of-the-art computational methods for modeling of red blood cell (RBC) rheology and dynamics in the micro...

journal_title：Annals of biomedical engineering

authors： Cristini V,Kassab GS

更新日期：2005-12-01 00:00:00

abstract：:In previous shoulder impact studies, the 50th-percentile male GHBMC human body finite-element model was shown to have good biofidelity regarding impact force, but under-predicted shoulder deflection by 80% compared to those observed in the experiment. The goal of this study was to validate the response of the GHBMC M5...

journal_title：Annals of biomedical engineering

authors： Park G,Kim T,Panzer MB,Crandall JR

更新日期：2016-08-01 00:00:00

abstract：:Local hemodynamics are an important factor in atherosclerosis, from the development of early lesions, to the assessment of stroke risk, to determining the ultimate fate of a mature plaque. Until recently, our understanding of arterial fluid dynamics and their relationship to atherosclerosis was limited by the use of i...

journal_title：Annals of biomedical engineering

authors： Steinman DA

更新日期：2002-04-01 00:00:00

abstract：:We propose a multiphysical mathematical model by fully coupling lipid deposition, monocytes/macrophages recruitment and angiogenesis to investigate the pathophysiological responses of an atherosclerotic plaque to the dynamic changes in the microenvironment. The time evolutions of cellular (endothelial cells, macrophag...

journal_title：Annals of biomedical engineering

authors： Guo M,Cai Y,He C,Li Z

更新日期：2019-02-01 00:00:00

abstract：:Electrical potentials in mechanically loaded bone have been implicated as signals in the bone remodeling cycle. Recently, interest has grown in exploiting this phenomenon to develop electrically active ceramics for implantation in hard tissue which may induce improved biological responses. Both polarized hydroxyapatit...

journal_title：Annals of biomedical engineering

authors： Baxter FR,Bowen CR,Turner IG,Dent AC

更新日期：2010-06-01 00:00:00

abstract：:A comparison was made between turbulence calculated by subtracting an ensemble average from the instantaneous velocity and calculations made with a high pass digital filter. Velocity was measured with a laser Doppler anemometer in vitro in the region of a normal porcine aortic valve and in patients with a hot film ane...

journal_title：Annals of biomedical engineering

authors： Walburn FJ,Sabbah HN,Stein PD

更新日期：1983-01-01 00:00:00

abstract：:In this study, we have developed an integrated microfluidic platform for actively patterning mammalian cells, where poly(ethylene glycol) (PEG) hydrogels play two important roles as a non-fouling layer and a dielectric structure. The developed system has an embedded array of PEG microwells fabricated on a planar indiu...

journal_title：Annals of biomedical engineering

authors： Tsutsui H,Yu E,Marquina S,Valamehr B,Wong I,Wu H,Ho CM

更新日期：2010-12-01 00:00:00

abstract：:The appropriateness of integrated information systems to the description of integrated biological systems is discussed. An integrated information system in the physiology of the regulation of respiration is argued to be a structural mathematical model of the system and the relational data base, which it can compute. I...

journal_title：Annals of biomedical engineering

authors： Yamamoto WS

更新日期：1983-01-01 00:00:00

abstract：:An adaptive neural network model that exhibits the optimality and homeostasis characteristics of the respiratory control system is described. Based upon the Hopfield network structure and a postulated Hebb-like respiratory synapse with correlational short-term potentiation, the model is capable of mimicking the normal...

journal_title：Annals of biomedical engineering

authors： Poon CS

更新日期：1993-09-01 00:00:00

abstract：:We describe a model for the Compound Action Currents (CACs) and Compound Action Potentials (CAPs) produced by a peripheral nerve bundle in vitro. The Single Fiber Action Currents (SFACs) and the extracellular Single Fiber Action Potentials (SFAPs) are calculated using a generalized volume conduction model. Frequency-d...

journal_title：Annals of biomedical engineering

authors： Wijesinghe RS,Gielen FL,Wikswo JP Jr

更新日期：1991-01-01 00:00:00

abstract：:The study was to explore the effects of BMP-2 gene modified canine bone marrow stromal cells (bMSCs) mediated by a nonviral PEI derivative (GenEscort™ II) in promoting bone formation in vitro and in vivo. Canine bMSCs were cultured and transfected with plasmids containing bone morphogenetic protein-2 gene (pBMP-2) or ...

journal_title：Annals of biomedical engineering

authors： Lü K,Zeng D,Zhang Y,Xia L,Xu L,Kaplan DL,Jiang X,Zhang F

更新日期：2011-06-01 00:00:00

abstract：:Adherence of a biological graft to the wound surface is the most important factor influencing the ultimate success of graft viability. A machine has been developed to test the adherence of biological graft materials to a substrate such as a wound surface. The peeling mode, which yields reproducible quantitative measur...

journal_title：Annals of biomedical engineering

authors： Dong C,Mead E,Skalak R,Fung YC,Debes JC,Zapata-Sirvent RL,Andree C,Greenleaf G,Cooper M,Hansbrough JF

更新日期：1993-01-01 00:00:00

abstract：:The manner in which energy from an explosion is transmitted into the brain is currently a highly debated topic within the blast injury community. This study was conducted to investigate the injury biomechanics causing blast-related neurotrauma in the rat. Biomechanical responses of the rat head under shock wave loadin...

journal_title：Annals of biomedical engineering

authors： Bolander R,Mathie B,Bir C,Ritzel D,VandeVord P

更新日期：2011-10-01 00:00:00

abstract：:We present an optical non-contact method for heart beat monitoring, based on the measurement of chest wall movements induced by the pumping action of the heart, which is eligible as a surrogate of electrocardiogram (ECG) in assessing both cardiac rate and heart rate variability (HRV). The method is based on the optica...

journal_title：Annals of biomedical engineering

authors： Morbiducci U,Scalise L,De Melis M,Grigioni M

更新日期：2007-01-01 00:00:00

abstract：:Dexterity of robots is highly required when it comes to integration for medical applications. Major efforts have been conducted to increase the dexterity at the distal parts of medical robots. This paper reports on developments toward integrating biocompatible conducting polymers (CP) into inherently dexterous concent...

journal_title：Annals of biomedical engineering

authors： Chikhaoui MT,Benouhiba A,Rougeot P,Rabenorosoa K,Ouisse M,Andreff N

更新日期：2018-10-01 00:00:00

abstract：:Hemodynamic forces are known to be able to induce an inflammatory phenotype in endothelial cells (ECs). The EC glycocalyx (GCX) is a dynamic structure which is regulated in response to different stimuli and hypothesized as an important contributor to the mechanotransduction of wall shear stresses (WSS). In this work, ...

journal_title：Annals of biomedical engineering

authors： Cooper S,McDonald K,Burkat D,Leask RL

更新日期：2017-09-01 00:00:00

abstract：:This is a personal historical essay on meanderings through the jungle of the microcirculatory swamp. Because one pretends that the wandering was purposefully exploratory, a few guideposts are placed at positions where one could discern blaze-marks from earlier wanderers, and the path cut a little wider along some of t...

journal_title：Annals of biomedical engineering

authors： Bassingthwaighte JB

更新日期：1987-01-01 00:00:00

abstract：:An endovascular technique using a stent has been developed and successfully applied in the treatment of wide neck aneurysms. A stent can facilitate thrombosis in the aneurysm pouch while maintaining biocompatible passage of the parent artery. Insertion of the stent changes the flow characteristics inside the aneurysm ...

journal_title：Annals of biomedical engineering

authors： Rhee K,Han MH,Cha SH

更新日期：2002-07-01 00:00:00

abstract：:Skeletal muscles can be injured by their own contractions. Such contraction-induced injury, often accompanied by delayed onset of muscle soreness, is a leading cause of the loss of mobility in the rapidly increasing population of elderly people. Unlike other types of muscle injuries which hurt almost exclusively those...

journal_title：Annals of biomedical engineering

authors： Givli S

更新日期：2015-02-01 00:00:00

abstract：:Auscultation is an important diagnostic indicator for cardiovascular analysis. Heart sound classification and analysis play an important role in the auscultative diagnosis. This study uses a combination of Mel-frequency cepstral coefficient (MFCC) and hidden Markov model (HMM) to efficiently extract the features for p...

journal_title：Annals of biomedical engineering

authors： Wang P,Lim CS,Chauhan S,Foo JY,Anantharaman V

更新日期：2007-03-01 00:00:00

abstract：:Impedance data, e.g., system responses, from perturbing small amplitude applied sinusoid signals of near DC to high kilohertz frequencies, give chemical information. Analysis of frequency-dependent imaginary and real impedance proceeds from equivalent analog circuit elements to chemical and physical significance deter...

journal_title：Annals of biomedical engineering

authors： Buck RP

更新日期：1992-01-01 00:00:00

abstract：:The scarcity of data available on the best approach for pulmonary fetal valve replacement or implantation necessitate an investigation on whether practices using adult transcatheter valves could be translated to fetal applications. The objective of this study is to evaluate the hemodynamic characteristics and the turb...

journal_title：Annals of biomedical engineering

authors： Hatoum H,Gooden S,Heitkemper M,Blum KM,Zakko J,Bocks M,Yi T,Wu YL,Wang Y,Breuer CK,Dasi LP

更新日期：2020-06-01 00:00:00

abstract：:Continuum-level finite element models (FEMs) of the humerus offer the ability to evaluate joint replacement designs preclinically; however, experimental validation of these models is critical to ensure accuracy. The objective of the current study was to quantify experimental full-field strain magnitudes within osteoar...

journal_title：Annals of biomedical engineering

authors： Kusins J,Knowles N,Columbus M,Oliviero S,Dall'Ara E,Athwal GS,Ferreira LM

更新日期：2020-12-01 00:00:00