An experimental evaluation of the use of an ensemble average for the calculation of turbulence in pulsatile flow.

abstract：:Pressure ulcer risk assessment might be optimized by incorporating the soft tissue reaction to mechanical loading in the currently used risk assessment scales. Cytokines, like IL-1alpha, IL-1RA, IL-8, and TNF-alpha, might be used to determine this tissue reaction, since they are released after 24 h of mechanical loadi...

journal_title：Annals of biomedical engineering

authors： Cornelissen LH,Bronneberg D,Bader DL,Baaijens FP,Oomens CW

更新日期：2009-05-01 00:00:00

abstract：:In the field of fluid flow within the human body, focus has been placed on the transportation of blood in the systemic circulation since the discovery of that system; but, other fluids and fluid flow phenomena pervade the body. Some of the most fascinating fluid flow phenomena within the human body involve fluids othe...

journal_title：Annals of biomedical engineering

authors： Zamir M,Moore JE Jr,Fujioka H,Gaver DP 3rd

更新日期：2010-03-01 00:00:00

abstract：:This discussion and review article focuses on the possible use of regenerative techniques applied to the interfaces between skin and medical implants. As is widely known, the area of contact between an implant and the skin--the skin-implant interface--is prone to recurrent and persistent problems originated from the l...

journal_title：Annals of biomedical engineering

authors： Peramo A,Marcelo CL

更新日期：2010-06-01 00:00:00

abstract：:An intelligent multichannel stimulator (IMS) has been designed and built for use in a cardiac research environment. The device is capable of measuring and responding to cardiac electrophysiological phenomena in real time with carefully timed and placed electrical stimuli. The system consists of 16 channels of sense/st...

journal_title：Annals of biomedical engineering

authors： Johnson PL,Newton JC,Rollins DL,Knisley SB,Ideker RE,Smith WM

更新日期：2002-02-01 00:00:00

abstract：:Kiani et al. (Kiani, M. F., A. R. Pries, L. L. Hsu, I. H. Sarelius, and G. R. Cokelet, Am. J. Physics. 266: H1822-H1828, 1994) suggested that blood velocity, hematocrit, and nodal pressures can oscillate spontaneously in large microvascular networks in the absence of biological control. This paper presents a model of ...

journal_title：Annals of biomedical engineering

authors： Carr RT,Lacoin M

更新日期：2000-06-01 00:00:00

abstract：:Point cathodal stimulation of cardiac tissue was shown previously to produce both a dog-bone shaped virtual cathode transverse to the muscle fibers and two longitudinal virtual anodes. We hypothesize that virtual anodes can cause a region of delayed activation, separating two regions of early activation caused by the ...

journal_title：Annals of biomedical engineering

authors： Wu J,Roden DM,Wikswo JP Jr

更新日期：2000-11-01 00:00:00

abstract：:For an optimal guidance of the rehabilitation therapy of stroke patients in an in-home setting, objective, and patient-specific performance assessment of arm movements is needed. In this study, metrics of hand movement relative to the pelvis and the sternum were estimated in 13 stroke subjects using a full body ambula...

journal_title：Annals of biomedical engineering

authors： van Meulen FB,Reenalda J,Buurke JH,Veltink PH

更新日期：2015-02-01 00:00:00

abstract：:This paper presents the permeability analysis of neuroactive drugs and correlation with in vivo brain/plasma ratios in a dynamic microfluidic blood-brain barrier (BBB) model. Permeability of seven neuroactive drugs (Ethosuximide, Gabapentin, Sertraline, Sunitinib, Traxoprodil, Varenicline, PF-304014) and trans-endothe...

journal_title：Annals of biomedical engineering

authors： Booth R,Kim H

更新日期：2014-12-01 00:00:00

abstract：:A major tissue engineering challenge is the creation of multilaminate scaffolds with layer-specific mechanical properties representative of native tissues, such as heart valve leaflets, blood vessels, and cartilage. For this purpose, poly(ethylene glycol) diacrylate (PEGDA) hydrogels are attractive materials due to th...

journal_title：Annals of biomedical engineering

authors： Tseng H,Cuchiara ML,Durst CA,Cuchiara MP,Lin CJ,West JL,Grande-Allen KJ

更新日期：2013-02-01 00:00:00

abstract：:This paper describes a finite volume method for modeling electrical activation in a sample of cardiac tissue using the bidomain equations. Microstructural features to the level of cleavage planes between sheets of myocardial fibers in the tissue are explicitly represented. The key features of this implementation compa...

journal_title：Annals of biomedical engineering

authors： Trew M,Le Grice I,Smaill B,Pullan A

更新日期：2005-05-01 00:00:00

abstract：:A nonintrusive method for the visualization of pulsatile flow velocity profiles is described. The method is based on the use of a photochromic dye that is added to the fluid being studied and a nitrogen laser which excites the dye producing a marker "line" whose movement can be photographed. A microcomputer is used as...

journal_title：Annals of biomedical engineering

authors： Poots K,Cobbold RS,Johnston KW,Appugliese R,Kassam M,Zuech PE,Hummel RL

更新日期：1986-01-01 00:00:00

abstract：:The pericellular matrix (PCM) is a region of tissue that surrounds chondrocytes in articular cartilage and together with the enclosed cells is termed the chondron. Previous studies suggest that the mechanical properties of the PCM, relative to those of the chondrocyte and the extracellular matrix (ECM), may significan...

journal_title：Annals of biomedical engineering

authors： Guilak F,Alexopoulos LG,Haider MA,Ting-Beall HP,Setton LA

更新日期：2005-10-01 00:00:00

abstract：:An algorithm to track a rat swimming in a Morris Water Maze has been developed. The system is automatically configured to any pool and relative suitable light conditions. It tracks the rat's position and head pose 10 times per second. The output data is displayed in a bitmap and also in a text file. The system was tes...

journal_title：Annals of biomedical engineering

authors： Hval ES,Barrett SF,Wilcox M,Bailey TA

更新日期：2004-08-01 00:00:00

abstract：:This experimental work focused on the sensor selection for the development of a needle-like instrument to treat small isolated cartilage defects with hydrogels. The aim was to identify the most accurate and sensitive imaging method to determine the location and size of defects compared to a gold standard (µCT). Only i...

journal_title：Annals of biomedical engineering

authors： Horeman T,Buiter EC,Pouran B,Stijntjes M,Dankelman J,Tuijthof GJM

更新日期：2018-11-01 00:00:00

abstract：:An MR image-based computational model of a murine KHT sarcoma is presented that allows the calculation of plasma fluid and solute transport within tissue. Such image-based models of solid tumors may be used to optimize patient-specific therapies. This model incorporates heterogeneous vasculature and tissue porosity to...

journal_title：Annals of biomedical engineering

authors： Pishko GL,Astary GW,Mareci TH,Sarntinoranont M

更新日期：2011-09-01 00:00:00

abstract：:The effects of wave propagation phenomena, namely global reflection coefficient (gamma G[omega]) and pulse wave velocity (Cph), are studied in a model of the coupled left ventricle/arterial system. The left ventricle consists of a time-varying elastance, while the arterial system is modeled as a single, uniform, elast...

journal_title：Annals of biomedical engineering

authors： Berger DS,Li JK,Noordergraaf A

更新日期：1995-11-01 00:00:00

abstract：:Current efforts to evaluate the performance of laparoscopic arterial fusion devices are limited to costly, time consuming, empirical studies. Thus, a finite element (FE) model, with the ability to predict device performance would improve device design and reduce development time and costs. This study introduces a mode...

journal_title：Annals of biomedical engineering

authors： Fankell DP,Kramer E,Cezo J,Taylor KD,Ferguson VL,Rentschler ME

更新日期：2016-11-01 00:00:00

abstract：:Disease and injury perturb the balance of processes associated with inflammation and tissue remodeling, resulting in positive feedback loops, exacerbation of disease and compromised tissue repair. Conversely, under homeostatic healthy conditions, these processes are tightly regulated through the expansion and/or recru...

journal_title：Annals of biomedical engineering

authors： Glowacki AJ,Gottardi R,Yoshizawa S,Cavalla F,Garlet GP,Sfeir C,Little SR

更新日期：2015-03-01 00:00:00

abstract：:Auscultation is an important diagnostic indicator for cardiovascular analysis. Heart sound classification and analysis play an important role in the auscultative diagnosis. This study uses a combination of Mel-frequency cepstral coefficient (MFCC) and hidden Markov model (HMM) to efficiently extract the features for p...

journal_title：Annals of biomedical engineering

authors： Wang P,Lim CS,Chauhan S,Foo JY,Anantharaman V

更新日期：2007-03-01 00:00:00

abstract：:Although diagnostic testing with auditory evoked potentials (EPs) has become routine, quantitative measurements of signal and noise are still lacking. In this study, current signal, power, noise power, and signal-to-noise ratio (SNR) estimation formulas are reviewed and applied to auditory brainstem response averaging...

journal_title：Annals of biomedical engineering

authors： Ozdamar O,Delgado RE

更新日期：1996-11-01 00:00:00

abstract：:Arteries are composed of multiple constituents that endow the wall with proper structure and function. Many vascular diseases are associated with prominent mechanical and biological alterations in the wall constituents. In this study, planar biaxial tensile test data of elastase-treated porcine aortic tissue (Chow et ...

journal_title：Annals of biomedical engineering

authors： Zeinali-Davarani S,Chow MJ,Turcotte R,Zhang Y

更新日期：2013-07-01 00:00:00

abstract：:Biochemical stimulation was applied in combination with cyclic mechanical strain to engineered vascular constructs made of isolated smooth muscle cells in a three-dimensional (3D) collagen type 1 matrix. Platelet-derived growth factor (PDGF) and transforming growth factor beta (TGF-beta) were added exogenously to the ...

journal_title：Annals of biomedical engineering

authors： Stegemann JP,Nerem RM

更新日期：2003-04-01 00:00:00

abstract：:Modern models of cardiac membranes are often highly complex and computationally expensive, particularly when used in long simulations of spatially extended models of cardiac tissue. Therefore, there is a need for simpler membrane models that preserve the features of the complex models deemed important. This communicat...

journal_title：Annals of biomedical engineering

authors： Oliver RA,Krassowska W

更新日期：2005-07-01 00:00:00

abstract：:A mathematical model is presented that estimates joint kinematics and kinetics using measured external resultant loads and readily available parameters. The musculo-skeletal system was represented by a planar three degrees of freedom open kinematic chain. Information extraction was limited to the flexion-extension fun...

journal_title：Annals of biomedical engineering

authors： Mazzà C,Cappozzo A

更新日期：2004-05-01 00:00:00

abstract：:The contractile power of the latissimus dorsi muscle (LDM) is used in skeletal muscle cardiac assist (SMCA) to augment the blood pumping ability of a failing heart. The LDM has three anatomically distinct, independently innervate segments-the transverse, oblique, and lateral. There are potential advantages to selectiv...

journal_title：Annals of biomedical engineering

authors： Thompson DR,Michele JJ,Cheever EA,George DT

更新日期：1999-01-01 00:00:00

abstract：:Numerical models of the mitral valve have been used to elucidate mitral valve function and mechanics. These models have evolved from simple two-dimensional approximations to complex three-dimensional fully coupled fluid structure interaction models. However, to date these models lack direct one-to-one experimental val...

journal_title：Annals of biomedical engineering

authors： Rabbah JP,Saikrishnan N,Yoganathan AP

更新日期：2013-02-01 00:00:00

abstract：:Atherosclerosis is an inflammatory disease of large and medium sized arteriole walls that is precipitated by elevated levels of low-density lipoprotein (LDL) cholesterol in the blood. However, the mechanisms that lead to the initiation of atherosclerosis are not fully understood. In this study, endothelial cells (ECs)...

journal_title：Annals of biomedical engineering

authors： Wei D,Chen Y,Tang C,Huang H,Liu L,Wang Z,Li R,Wang G

更新日期：2013-03-01 00:00:00

abstract：:One of the major functions of the cardiovascular system is to deliver blood to the microcirculation where exchange of mass and energy can take place. In the present article, we will provide an overview of the state-of-the-art computational methods for modeling of red blood cell (RBC) rheology and dynamics in the micro...

journal_title：Annals of biomedical engineering

authors： Cristini V,Kassab GS

更新日期：2005-12-01 00:00:00

abstract：:The development of prevention strategies is critical to address the rising prevalence of sport-related concussions. Visual and sensory performance may influence an individual's ability to interpret environmental cues, anticipate opponents' actions, and create appropriate motor responses limiting the severity of an imp...

journal_title：Annals of biomedical engineering

authors： Harpham JA,Mihalik JP,Littleton AC,Frank BS,Guskiewicz KM

更新日期：2014-01-01 00:00:00

abstract：:Early intervention programs aim at improving cognitive and motor outcomes of preterm infants. Intensive custom-tailored training activities are usually accompanied by assessment procedures, which have shortcomings, such as subjectivity, complex setups, and need for structured environments. A novel sensorized system, c...

journal_title：Annals of biomedical engineering

authors： Rihar A,Sgandurra G,Beani E,Cecchi F,Pašič J,Cioni G,Dario P,Mihelj M,Munih M

更新日期：2016-12-01 00:00:00