Abstract：
:An endovascular technique using a stent has been developed and successfully applied in the treatment of wide neck aneurysms. A stent can facilitate thrombosis in the aneurysm pouch while maintaining biocompatible passage of the parent artery. Insertion of the stent changes the flow characteristics inside the aneurysm pouch, which can affect the intra-aneurysmal embolization process. The purpose of this study is to clarify the velocity and wall shear stress changes that are caused by stenting in fusiform and lateral aneurysm models. We used a flow visualization technique that incorporated a photochromic dye in order to observe the flow fields and measure the wall shear rates. The intra-aneurysmal flow motion was significantly reduced in the stented aneurysm models. Coherent inflow along the distal wall of the aneurysm was diminished and inflow was distributed along the pores of the stent wall in the stented models. Also, sluggish intra-aneurysmal vortex motion was well maintained in the stented aneurysm models during the deceleration phase. A less porous stent generally reduced the intraneurysmal fluid motion further, but the porosity effect was not significant. The magnitude and pulsatility of the wall shear rate were reduced by stenting, and the reductions were more significant in the lateral aneurysm models compared to the fusiform aneurysm models. The hemodynamic changes that were observed in our study can help explain the efficacy of in vivo thrombus formation caused by stenting.
journal_name
Ann Biomed Engjournal_title
Annals of biomedical engineeringauthors
Rhee K,Han MH,Cha SHdoi
10.1114/1.1500406subject
Has Abstractpub_date
2002-07-01 00:00:00pages
894-904issue
7eissn
0090-6964issn
1573-9686journal_volume
30pub_type
杂志文章abstract：:A number of human head finite element (FE) models have been developed from different research groups over the years to study the mechanisms of traumatic brain injury. These models can vary substantially in model features and parameters, making it important to evaluate whether simulation results from one model are read...
journal_title：Annals of biomedical engineering
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journal_title：Annals of biomedical engineering
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journal_title：Annals of biomedical engineering
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