Prediction of the biomechanical effects of compression therapy on deep veins using finite element modelling.

Abstract:

:Clinicians generally assume that Medical Compression Stockings (MCS) work by reducing vein luminal diameter and, in this way, help to prevent blood pooling. Conflicting results have been reported however in the case of lower leg deep veins which call into question this hypothesis. The purpose of this contribution is to study the biomechanical response of the main lower leg deep veins to elastic compression and muscle contraction with the objective of improving our current understanding of the mechanism by which MCS convey their benefits. The development of a finite-element model of a slice of the lower leg from MR images is detailed. Analysis of the finite-element model shows that the contribution of the MCS to the deep vein diameter reduction is rather small, and in fact negligible, compared to that of the contracting muscle (3 and 9% decrease in the vein cross-sectional area with a grade II compression stocking in the supine and standing positions respectively, while complete collapse was obtained at the end of muscle activation). A more accurate representation of the muscle activation is eventually proposed to study the effect of muscle contraction on a vein wall. The impact on the venous blood draining is discussed.

journal_name

Ann Biomed Eng

authors

Rohan PY,Badel P,Lun B,Rastel D,Avril S

doi

10.1007/s10439-014-1121-6

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

314-24

issue

2

eissn

0090-6964

issn

1573-9686

journal_volume

43

pub_type

杂志文章
  • Stochastic system identification of skin properties: linear and wiener static nonlinear methods.

    abstract::Wiener static nonlinear system identification was used to study the linear dynamics and static nonlinearities in the response of skin and underlying tissue under indentation in vivo. A device capable of measuring the dynamic mechanical properties of bulk skin tissue was developed and it incorporates a custom-built Lor...

    journal_title:Annals of biomedical engineering

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10439-012-0580-x

    authors: Chen Y,Hunter IW

    更新日期:2012-10-01 00:00:00

  • In vitro temperature map of cardiac ablation demonstrates the effect of flow on lesion development.

    abstract::This paper presents an in vitro temperature mapping study of bovine cardiac tissue during radiofrequency ablation. The objectives were to: (i) develop a technique for measuring the spatial and temporal temperature distribution in the tissue and in the blood during ablation, and (ii) use the temperature measurements to...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.1310218

    authors: Jain MK,Wolf PD

    更新日期:2000-09-01 00:00:00

  • Noninvasive recovery of acinar anatomic information from CO2 expirograms.

    abstract::A numerical single path model of respiratory gas exchange with distributed alveolar gas sources was used to estimate the anatomical changes in small peripheral airways such as occur in chronic obstructive pulmonary diseases (COPD). A previous sensitivity analysis of the single path model showed that decreasing total a...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02368236

    authors: Schwardt JD,Neufeld GR,Baumgardner JE,Scherer PW

    更新日期:1994-05-01 00:00:00

  • A Model to Study Articular Cartilage Mechanical and Biological Responses to Sliding Loads.

    abstract::In physiological conditions, joint function involves continuously moving contact areas over the tissue surface. Such moving contacts play an important role for the durability of the tissue. It is known that in pathological joints these motion paths and contact mechanics change. Nevertheless, limited information exists...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-015-1543-9

    authors: Schätti OR,Gallo LM,Torzilli PA

    更新日期:2016-08-01 00:00:00

  • Development of a side-view chamber for studying cell-surface adhesion under flow conditions.

    abstract::Observing microscopic specimens is often useful in studies of cellular interaction with a vascular wall. We have developed an in vitro side-view flow chamber that permits observations from the side of the cell's contact with various adhesive surfaces under dynamic flow conditions. This side-view flow chamber consists ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02684196

    authors: Cao J,Usami S,Dong C

    更新日期:1997-05-01 00:00:00

  • The Impact of Anti-tumor Agents on ER-Positive MCF-7 and HER2-Positive SKBR-3 Breast Cancer Cells Biomechanics.

    abstract::Studying human cancer from a biomechanical perspective may contribute to pathogenesis understanding which leads to the malignancy. In this study, biomechanics of suspended and adhered breast cancer cells were investigated via the micropipette aspiration method with special emphasis on comparing the cell stiffness and ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-019-02284-3

    authors: Metsiou DN,Siatis KE,Giannopoulou E,Papachristou DJ,Kalofonos HP,Koutras A,Athanassiou G

    更新日期:2019-08-01 00:00:00

  • Theory of the oscillometric maximum and the systolic and diastolic detection ratios.

    abstract::It is proposed that the maximum in cuff pressure oscillations during oscillometry is due to the buckling of the brachial artery under a cuff. This theory is investigated by means of a mathematical model of oscillatometry that includes the mechanics of the occlusive arm cuff, the arterial pressure pulse waveform, and t...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02368225

    authors: Drzewiecki G,Hood R,Apple H

    更新日期:1994-01-01 00:00:00

  • Theoretical study of the effects of vascular smooth muscle contraction on strain and stress distributions in arteries.

    abstract::To study the effects of smooth muscle contraction and relaxation on the strain and stress distribution in the vascular wall, a mathematical model was proposed. The artery was assumed to be a thick-walled orthotropic tube made of nonlinear, incompressible elastic material. Considering that the contraction of smooth mus...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.191

    authors: Rachev A,Hayashi K

    更新日期:1999-07-01 00:00:00

  • Rapid platelet accumulation leading to thrombotic occlusion.

    abstract::Platelet thrombosis under arterial conditions remains a large clinical problem. Previous in vitro experiments have concentrated on early adherence without thrombotic occlusion. We have developed a controllable hemodynamic system that creates intravascular thrombosis to occlusion. Lightly heparinized (3.5 USP units/mL)...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-011-0296-3

    authors: Para A,Bark D,Lin A,Ku D

    更新日期:2011-07-01 00:00:00

  • Cerebrovascular transmural pressure and autoregulation.

    abstract::The cerebral blood flow (CBF) response to changes in perfusion pressure mediated through decreases in arterial pressure, increases in cerebrospinal fluid (CSF) pressure and increases in jugular venous pressure was studied in anesthetized dogs. A preparation was developed in which each of the three relevant pressures c...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02584249

    authors: Wagner EM,Traystman RJ

    更新日期:1985-01-01 00:00:00

  • Vortex ring formation in the left ventricle of the heart: analysis by 4D flow MRI and Lagrangian coherent structures.

    abstract::Recent studies suggest that vortex ring formation during left ventricular (LV) rapid filling is an optimized mechanism for blood transport, and that the volume of the vortex ring is an important measure. However, due to lack of quantitative methods, the volume of the vortex ring has not previously been studied. Lagran...

    journal_title:Annals of biomedical engineering

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10439-012-0615-3

    authors: Töger J,Kanski M,Carlsson M,Kovács SJ,Söderlind G,Arheden H,Heiberg E

    更新日期:2012-12-01 00:00:00

  • Redirection of neurite outgrowth by coupling chondroitin sulfate proteoglycans to polymer membranes.

    abstract::Upon nerve injury, the body creates an environment consisting of permissive and non-permissive cues that instruct the function of cells involved in nerve repair. Among other roles, the developing extracellular matrix (ECM) acts as an underlying substrate to guide the union of neurites extending from the proximal stump...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-014-0991-y

    authors: Man AJ,Leach JK,Bannerman P

    更新日期:2014-06-01 00:00:00

  • Reporter Scaffolds for Clinically Relevant Cell Transplantation Studies.

    abstract::There are a number of cell therapies that are either in clinical trials or moving toward clinical trials, particularly for diseases of the retina. One of the challenges with cell therapies is tracking the status of cells over time. Genetic manipulation can facilitate this, but it can limit the clinical application of ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-019-02393-z

    authors: Bolger M,Groynom R,Bogie K,Lavik E

    更新日期:2020-07-01 00:00:00

  • Biomechanical properties of esophagus during systemic treatment with epidermal growth factor in rats.

    abstract::The epidermal growth factor (EGF) is a growth factor with effects on many cell types and tissue. Morphometric and passive biomechanical properties were studied in isolated segments of the esophagus in 22 EGF-treated rats and 12 control rats. The rats were divided into groups with EGF treatment for 2, 4, 7, and 14 days...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.1575758

    authors: Zhao J,Yang J,Vinter-Jensen L,Zhuang F,Gregersen H

    更新日期:2003-06-01 00:00:00

  • Mitral Valve Regurgitation with a Rotary Left Ventricular Assist Device: The Haemodynamic Effect of Inlet Cannulation Site and Speed Modulation.

    abstract::Mitral valve regurgitation (MVR) is common in patients receiving left ventricular assist device (LVAD) support, however the haemodynamic effect of MVR is not entirely clear. This study evaluated the haemodynamic effect of MVR with LVAD support and the influence of inflow cannulation site and LVAD speed modulation. Lef...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-016-1579-5

    authors: Gregory SD,Stevens MC,Wu EL,Pauls JP,Kleinheyer M,Fraser JF

    更新日期:2016-09-01 00:00:00

  • Finite element modeling of coupled diffusion with partitioning in transdermal drug delivery.

    abstract::The finite element method is employed to simulate two-dimensional (axisymmetric) drug diffusion from a finite drug reservoir into the skin. The numerical formulation is based on a general mathematical model for multicomponent nonlinear diffusion that takes into account the coupling effects between the different compon...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-005-5788-6

    authors: Rim JE,Pinsky PM,van Osdol WW

    更新日期:2005-10-01 00:00:00

  • Skull flexure as a contributing factor in the mechanism of injury in the rat when exposed to a shock wave.

    abstract::The manner in which energy from an explosion is transmitted into the brain is currently a highly debated topic within the blast injury community. This study was conducted to investigate the injury biomechanics causing blast-related neurotrauma in the rat. Biomechanical responses of the rat head under shock wave loadin...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-011-0343-0

    authors: Bolander R,Mathie B,Bir C,Ritzel D,VandeVord P

    更新日期:2011-10-01 00:00:00

  • Concussion Risk Between Individual Football Players: Survival Analysis of Recurrent Events and Non-events.

    abstract::Concussion tolerance and head impact exposure are highly variable among football players. Recent findings highlight that head impact data analyses need to be performed at the subject level. In this paper, we describe a method of characterizing concussion risk between individuals using a new survival analysis technique...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-020-02675-x

    authors: Rowson S,Campolettano ET,Duma SM,Stemper B,Shah A,Harezlak J,Riggen L,Mihalik JP,Brooks A,Cameron KL,Svoboda SJ,Houston MN,McAllister T,Broglio S,McCrea M

    更新日期:2020-11-01 00:00:00

  • A new bioreactor for the development of tissue-engineered heart valves.

    abstract::This paper reports the design, manufacturing, and characterization of a new bioreactor dedicated to the development of tissue-engineered heart valve substitutes. First, a comprehensive review of the state of the art in bioreactors is presented and a rigorous classification is put forward. The existing bioreactors foun...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-009-9646-9

    authors: Ruel J,Lachance G

    更新日期:2009-04-01 00:00:00

  • Soft 3D-Printed Phantom of the Human Kidney with Collecting System.

    abstract::Organ models are used for planning and simulation of operations, developing new surgical instruments, and training purposes. There is a substantial demand for in vitro organ phantoms, especially in urological surgery. Animal models and existing simulator systems poorly mimic the detailed morphology and the physical pr...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-016-1757-5

    authors: Adams F,Qiu T,Mark A,Fritz B,Kramer L,Schlager D,Wetterauer U,Miernik A,Fischer P

    更新日期:2017-04-01 00:00:00

  • Recurrent wavefront morphologies: a method for quantifying the complexity of epicardial activation patterns.

    abstract::We have developed a method for quantifying the complexity of activation patterns observed during ventricular fibrillation (VF) that is based on our previously reported methodology for decomposing epicardial mapping data into a set of isolated wavefronts. One-half second datasets are acquired from a 21 x 24 array of un...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02684160

    authors: Rogers JM,Usui M,KenKnight BH,Ideker RE,Smith WM

    更新日期:1997-09-01 00:00:00

  • Magnetic (eddy-current) electroventilation in the dog.

    abstract::Magnetic (eddy-current) stimulation of the inspiratory motor nerves in the neck of the anesthetized dog was achieved. Using a 10-turn coil wound around the base of the neck and a train of pulses (25/s), inspiration was produced by tetanic contraction of the inspiratory muscles. The volume of air inspired increased wit...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/BF02368176

    authors: Geddes LA,Mouchawar G,Bourland JD,ElAbbady T,Nyenhuis J

    更新日期:1993-05-01 00:00:00

  • Characterizing the variability of system kernel and input estimates.

    abstract::The identification of the input to, or kernels of, a system using nonparametric representations and least-squares estimation is becoming increasingly popular. Nonparametric representations avoid making a priori assumptions about the input or having detailed knowledge about the system, and only need to guarantee known ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.110

    authors: Verotta D

    更新日期:1998-09-01 00:00:00

  • Restoring Ovarian Endocrine Function with Encapsulated Ovarian Allograft in Immune Competent Mice.

    abstract::Premature ovarian insufficiency (POI) is a major complication of cytotoxic treatments due to extreme ovarian sensitivity to chemotherapy and radiation. In pediatric cancer patients modern therapy has improved the long-term survival to over 80% in the United States. However, these cancer survivors face long-term health...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-016-1780-6

    authors: David A,Day JR,Cichon AL,Lefferts A,Cascalho M,Shikanov A

    更新日期:2017-07-01 00:00:00

  • Correction to: A High-Precision and Miniature Fiber Bragg Grating-Based Force Sensor for Tissue Palpation During Minimally Invasive Surgery.

    abstract::The second equation in the section "Definition of Objective Functions and Constraints" was corrected to fix a mismatch between the PDF and HTML versions of the article. ...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s10439-019-02413-y

    authors: Lv C,Wang S,Shi C

    更新日期:2020-01-01 00:00:00

  • Strontium ranelate prevents bone loss in a rat model of localized muscle paralysis.

    abstract::Twenty-one 3.5-month-old female Sprague-Dawley rats were randomly assigned to three groups: BTX group, in which each rat received a single intramuscular injection of 2 U of Clostridium botulinum toxin (BTX) in the quadriceps femoris muscle of the right hind limb; BTX + SR group, in which each rat received a BTX inject...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-011-0406-2

    authors: Sheng ZF,Ma YL,Tong D,Fang DY,Liang QC,Liu LH,Zhang J,Liao EY

    更新日期:2012-03-01 00:00:00

  • Multi-molecular gradients of permissive and inhibitory cues direct neurite outgrowth.

    abstract::Correct development of neuronal tracts requires the coordination of multiple permissive and inhibitory signals. By generating an in vitro microenvironment using soft lithography and microfluidic techniques, multiple guidance cues can be presented in a spatially defined way. Here we evaluated how neurites of dorsal roo...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-008-9486-z

    authors: Li GN,Liu J,Hoffman-Kim D

    更新日期:2008-06-01 00:00:00

  • Importance of temperature and humidity in the measurement of pulmonary oxygen uptake per breath during anesthesia.

    abstract::Traditionally, measurement of pulmonary O2 uptake uses mass balance of N2 to correct for differences between inspired and expired volume (V) due to temperature (T) and relative humidity (RH). Often during anesthesia, N2 balance cannot be invoked due to high inspired O2 fraction (FIO2) or nonsteady state conditions. Th...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1114/1.1312184

    authors: Breen PH

    更新日期:2000-09-01 00:00:00

  • Biomechanical Response Targets of Adult Human Ribs in Frontal Impacts.

    abstract::Thorax injuries mainly due to rib fractures have been associated with high rates of morbidity and mortality in motor vehicle crashes. Thoracic biomechanics has been studied extensively, but there are no robust biomechanical response targets for ribs that consider age, sex, body size, and vulnerability factors. The obj...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-020-02613-x

    authors: Kang YS,Kwon HJ,Stammen J,Moorhouse K,Agnew AM

    更新日期:2021-02-01 00:00:00

  • Developments and Control of Biocompatible Conducting Polymer for Intracorporeal Continuum Robots.

    abstract::Dexterity of robots is highly required when it comes to integration for medical applications. Major efforts have been conducted to increase the dexterity at the distal parts of medical robots. This paper reports on developments toward integrating biocompatible conducting polymers (CP) into inherently dexterous concent...

    journal_title:Annals of biomedical engineering

    pub_type: 杂志文章

    doi:10.1007/s10439-018-2038-2

    authors: Chikhaoui MT,Benouhiba A,Rougeot P,Rabenorosoa K,Ouisse M,Andreff N

    更新日期:2018-10-01 00:00:00