Treatment of polycythemia vera with hydroxyurea.

abstract：:This report is to make the general scientific community aware of availability of human tissues through this network. During the short period of its existence, this network has developed useful procedures for distributing human tumor tissue in a rapid, scientifically useful, cost-effective manner to investigators to wh...

journal_title：Cancer

authors： Clausen KP,Grizzle WE,Livolsi V,Newton WA Jr,Aamodt R

更新日期：1989-04-01 00:00:00

abstract：:The potential of using a blood test enumerating oncofetal ferritin-bearing lymphocytes (FBL) as a biomarker for early breast cancer was further explored. Nine hundred women attending a high-risk breast cancer clinic and 2500 normal-risk women were physically examined and their blood drawn for FBL determination using a...

journal_title：Cancer

authors： Moroz C,Kahn M,Ron E,Luria H,Chaimoff C

更新日期：1989-08-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA) was measured in extracts of cell suspensions from tumors of the colon, stomach, breast, lung and kidney. Cell suspensions were also obtained from normal tissue surrounding the primary tumors. The number of neoplastic cells in each cell suspension was determined by cytologic criteria. Hig...

journal_title：Cancer

authors： MacSween JM,Anderson GH

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Despite Helicobacter pylori (HP) eradication, individuals can still develop gastric cancer (GC). Prior studies have demonstrated that nonaspirin nonsteroidal anti-inflammatory drugs (NA-NSAIDs) reduce the risk of GC, but this may be caused by immortal time bias and failure to adjust for HP status. The object...

journal_title：Cancer

authors： Li B,Cheung KS,Wong IY,Leung WK,Law S

更新日期：2021-01-20 00:00:00

abstract：:A case of acute renal failure secondary to bilateral renal vein occlusion by a retroperitoneal plasmacytoma is described. The use of low-risk radiographic techniques including radionuclide venography and a computerized axial tomography (CAT) scan made a rapid and accurate diagnosis possible. Fatal hemorrhage occurred ...

journal_title：Cancer

authors： Marks ES,Lee KM

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Data from the Health Care Financing Administration's (HCFA) Medicare Health Outcomes Survey (MHOS) of patients enrolled in managed care services through Medicare were analyzed. The MHOS provided baseline estimates of quality of life of cancer survivors in comparison to a frequency age-matched cohort of nonca...

journal_title：Cancer

authors： Baker F,Haffer SC,Denniston M

更新日期：2003-02-01 00:00:00

abstract：:CEA-like material was found in 51 of 62 primary human breast carcinomas and in only 2 of 12 fibroadenomas. Levels of carcinoma CEA-like material correlated weakly with cytoplasmic estradiol receptor levels, total cytosol estrogens, and cytosol progesterone. Levels of CEA-like material showed no significant correlation...

journal_title：Cancer

authors： Duffy MJ,O'Connell M,O'Sullivan F,McKenna B,Allen MA,McDonnell L

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Multiple cell-signaling ligands and receptors-including vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF), endothelial growth factor (EGF), v-akt murine thymoma viral oncogene homolog (AKT), platelet-derived growth factor (PDGF), mitogen-activated protein kinase (MAPK), and 70-kilod...

journal_title：Cancer

authors： Abdeen A,Chou AJ,Healey JH,Khanna C,Osborne TS,Hewitt SM,Kim M,Wang D,Moody K,Gorlick R

更新日期：2009-11-15 00:00:00

abstract：:Regressing atypical histiocytosis (RAH) of skin is a cutaneous noduloulcerative proliferation of atypical neoplastic histiocytes with concomitant polymorphous inflammation, frequently pronounced epidermal hyperplasia, and an unexpectedly indolent biologic course. Spontaneous regression and recurrence without systemic ...

journal_title：Cancer

authors： Flynn KJ,Dehner LP,Gajl-Peczalska KJ,Dahl MV,Ramsay N,Wang N

更新日期：1982-03-01 00:00:00

abstract：:Among the patients showing evidence of cerebral metastases without previously known cancer history, lung cancer has been found 37 times as the primary tumor in our institution. There were 34 men and three women and all but two were heavy smokers. Only one presented at diagnosis with thoracic symptoms but the chest rad...

journal_title：Cancer

authors： Trillet V,Catajar JF,Croisile B,Turjman F,Aimard G,Bourrat C,Bret P,Carrie C,Chassard JL,Chauvin F

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Patients with bulky laryngopharyngeal masses and a relative or absolute contraindication to general anesthesia present diagnostic difficulties. In the current study, the authors assessed the utility of transcutaneous ultrasound-guided Tru-Cut biopsy (USGTCB) under local anesthesia in such individuals. METHO...

journal_title：Cancer

authors： Ansarin M,De Fiori E,Preda L,Maffini F,Bruschini R,Calabrese L,Jereczek-Fossa BA,Chiesa F,Bellomi M

更新日期：2007-06-01 00:00:00

abstract：:In a pathologic review of 1224 cases of endometrial carcinoma, 1023 were confirmed cases of endometrial carcinoma. Fifty-six (5.5%) were clear-cell adenocarcinoma (CCE). Fifteen cases of "secretory carcinoma" (SCE) were examined for comparison. Fifty-five patients with CCE and all with SCE were followed for at least f...

journal_title：Cancer

authors： Christopherson WM,Alberhasky RC,Connelly PJ

更新日期：1982-04-15 00:00:00

abstract：:From 1975 until 1984 37 children with newly diagnosed Hodgkin's disease were treated with six mechlorethamine, vincristine, procarbazine, and prednisone (MOPP) courses with or without involved field radiotherapy (25 Gy) independent of the stage of their disease. Patients with small lymph node tumors (less than 4 cm) r...

journal_title：Cancer

authors： Behrendt H,Van Bunningen BN,Van Leeuwen EF

更新日期：1987-06-01 00:00:00

abstract：:From November 1973 to May 1986, 50 patients with Stage I epithelial ovarian cancer were treated at the University of Kentucky Medical Center (Lexington, KY) with oral Alkeran (melphalan) chemotherapy after primary surgery. Twenty-two patients had Grade 1 tumors, 23 patients had Grade 2 tumors, and five patients had Gr...

journal_title：Cancer

authors： Gallion HH,van Nagell JR,Donaldson ES,Higgins RV,Powell DE,Kryscio RJ

更新日期：1989-03-15 00:00:00

abstract：BACKGROUND:Parathyroid hormone-related peptide (PTHrP) is a tumor-derived circulating factor that has been associated with hypercalcemia of malignancy. The role of PTHrP as a prognostic indicator remains unclear. Studies suggest that it may function as a growth factor; and, recently, the ability of PTHrP to induce cyto...

journal_title：Cancer

authors： Deans C,Wigmore S,Paterson-Brown S,Black J,Ross J,Fearon KC

更新日期：2005-05-01 00:00:00

abstract：:A pulmonary blastoma in a 52-year-old Japanese man was serially transplanted into athymic nude mice. This report emphasizes the characteristics of the neoplasm seen on light and electron microscopic examination. The original tumor consisted of branching tubular structures and primitive mesenchymal components with a fe...

journal_title：Cancer

authors： Tamai S,Kameya T,Shimosato Y,Tsumuraya M,Wada T

更新日期：1980-09-15 00:00:00

abstract：BACKGROUND:Inhibitors of the mammalian target of rapamycin (mTOR) are emerging as promising therapies for metastatic renal cell carcinoma (RCC). Because rational treatment strategies require understanding the activation status of the underlying signaling pathway being targeted at the desired stage of disease, the autho...

journal_title：Cancer

authors： Abou Youssif T,Fahmy MA,Koumakpayi IH,Ayala F,Al Marzooqi S,Chen G,Tamboli P,Squire J,Tanguay S,Sircar K

更新日期：2011-01-15 00:00:00

abstract：:Twenty-two patients with cancer of the colon and rectum were studied: preoperative and postoperative cell-mediated and humoral immune factors were assessed, and local concentration of immunoglobulins in tumor tissue and in normal mucosa were measured. Lymphocyte function was found to be reduced in 50% of stage A and B...

journal_title：Cancer

authors： Shafir M,Bekesi JG,Papatestas A,Slater G,Aufses AH Jr

更新日期：1980-08-15 00:00:00

abstract：:In 25 patients under treatment or during follow-up for acute lymphoblastic leukemia magnetic resonance imaging (MRI) of both knees was compared to history and physical examination to detect osteonecrosis. Results of MRI were classified as: O, normal bone marrow (BM); 1, diffuse decrease in signal intensity; 2, circums...

journal_title：Cancer

authors： Pieters R,van Brenk AI,Veerman AJ,van Amerongen AH,van Zanten TE,Golding RP

更新日期：1987-12-15 00:00:00

abstract：:K-ras gene mutation in colorectal tumors from patients with familial polyposis coli were investigated using oligonucleotide probes specific for a mutation at codon 12, 13, or 61 of the K-ras gene. The authors examined 22 colorectal carcinomas and 51 colorectal adenomas from 41 familial polyposis coli patients and obse...

journal_title：Cancer

authors： Sasaki M,Sugio K,Sasazuki T

更新日期：1990-06-01 00:00:00

abstract：:The cytologic results of 34 fine-needle aspiration (FNA) biopsies of the central nervous system (CNS) are reported. There were 31 intraoperative biopsies performed at the time of craniotomy. All the cases were diagnosed using direct smear preparations stained with Papanicolaou and Diff-Quik (Harleco, NJ) stains. The s...

journal_title：Cancer

authors： Silverman JF,Timmons RL,Leonard JR 3rd,Hardy IM,Harris LS,O'Brien K,Norris HT

更新日期：1986-09-01 00:00:00

abstract：:We have demonstrated by tissue assay and immunohistochemical techniques that tumor cells appear to be the source of the increased histaminase activity found in 60% of ascitic fluids from patients with ovarian carcinoma. The histaminase activity in 64% of tumor tissues studied was greater than 100 U/g of tissue, a valu...

journal_title：Cancer

authors： Ettinger DS,Rosenshein NB,Parmley TH,Mendelsohn G,Baylin SB

更新日期：1980-05-15 00:00:00

abstract：BACKGROUND:Notwithstanding some controversy regarding the benefits of screening mammography, it is generally assumed that the effects are the same for women of all race/ethnic groups. Yet evidence for its efficacy from clinical trial studies comes primarily from the study of white women. It is likely that mammography i...

journal_title：Cancer

authors： Jones BA,Patterson EA,Calvocoressi L

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Survivors of childhood leukemia/lymphoma are at increased risk for reduced bone mineral density (BMD). The authors sought to determine the frequency of reduced BMD detected by off-therapy surveillance, factors associated with reduced BMD, and the association of reduced BMD with fractures. METHODS:This cross...

journal_title：Cancer

authors： Bloomhardt HM,Sint K,Ross WL,Rotatori J,Ness K,Robinson C,Carpenter TO,Chow EJ,Kadan-Lottick NS

更新日期：2020-01-01 00:00:00

abstract：:Fiberoptic endoscopic examination and biopsy of the nasopharynx was done in 130 patients as a prospective study. They all had elevated titers of antibodies against the viral capsid antigen of Epstein-Barr virus but no symptoms or signs of nasopharyngeal carcinoma. Each underwent a biopsy from six fixed sites in the na...

journal_title：Cancer

authors： Wei WI,Sham JS,Zong YS,Choy D,Ng MH

更新日期：1991-06-15 00:00:00

abstract：:Hereditary adenomatosis of the colon and rectum (HACR) is associated with a wide variety of extracolonic manifestations. Two cases of neoplasia involving the adrenal gland are reported, one adenoma and one carcinoma. The literature relating these lesions to HACR and other syndromes of malignant and nonmalignant growth...

journal_title：Cancer

authors： Painter TA,Jagelman DG

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:The current study assessed the contribution of spinal irradiation to the treatment outcome of patients with intracranial germinoma. METHODS:Clinical data from 180 patients with intracranial germinoma, who were treated with radiotherapy and/or chemotherapy from 1980 to 2001, were collected from 6 institution...

journal_title：Cancer

authors： Shikama N,Ogawa K,Tanaka S,Toita T,Nakamura K,Uno T,Ohnishi H,Itami J,Tada T,Saeki N

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The objective of this study was to determine the potential economic implications resulting from using exemestane (EXE), a new steroidal, irreversible aromatase inactivator, compared with megestrol acetate (MA) in patients with advanced breast carcinoma. METHODS:The model used the clinical results from the m...

journal_title：Cancer

authors： Hillner BE,Radice D

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Screening over many years is required to optimize reductions in colorectal cancer (CRC) mortality. However, no prior trials have compared strategies for obtaining long-term adherence. METHODS:Systems of Support to Increase Colorectal Cancer Screening and Follow-Up was implemented in an integrated health car...

journal_title：Cancer

authors： Green BB,Anderson ML,Cook AJ,Chubak J,Fuller S,Meenan RT,Vernon SW

更新日期：2017-11-15 00:00:00

abstract：BACKGROUND:Preclinical and clinical studies suggest synergistic activity between somatostatin analogues and mammalian target of rapamycin inhibitors. The activity and safety of everolimus was assessed in combination with octreotide long-acting repeatable (LAR) in patients with neuroendocrine tumors (NETs) of gastroente...

journal_title：Cancer

authors： Bajetta E,Catena L,Fazio N,Pusceddu S,Biondani P,Blanco G,Ricci S,Aieta M,Pucci F,Valente M,Bianco N,Mauri CM,Spada F

更新日期：2014-08-15 00:00:00