Special communication. The Cooperative Human Tissue Network.

abstract：:One-hundred and fifty-one adults with acute non-lymphocytic leukemia (ANLL) were entered into an Eastern Cooperative Oncology Group protocol (EST-1473) comparing twice daily cytosine arabinoside and thioguanine (AT) with weekly cyclophosphamide, cytosine arabinoside, and methotrexate (CAM) for remission induction. Of ...

journal_title：Cancer

authors： Skeel RT,Costello W,Bennett JM,Oken MM,Tobin MS,Bertino JR,Marsh JC,Carbone PP

更新日期：1980-01-15 00:00:00

abstract：BACKGROUND:The majority of colorectal carcinomas, if not all, arise from a benign adenoma. The DNA of the carcinomatous cells frequently has mutations in several genes. However, it is not exactly clear when during the neoplastic process each mutation develops. An adenoma with an area of in situ carcinoma provides an op...

journal_title：Cancer

authors： Zauber NP,Sabbath-Solitare M,Marotta SP,Bishop DT

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Fludarabine plus busulfan (FB) and fludarabine plus melphalan (FM) are 2 widely used reduced-intensity conditioning (RIC) regimens for allogeneic hematopoietic stem cell transplantation (allo-SCT). METHODS:The current survey compared transplantation outcomes for a cohort of 394 acute myeloid leukemia (AML) ...

journal_title：Cancer

authors： Baron F,Labopin M,Peniket A,Jindra P,Afanasyev B,Sanz MA,Deconinck E,Nagler A,Mohty M

更新日期：2015-04-01 00:00:00

abstract：:Malignant lymphomas with multilobated nuclei are rare, recently recognized neoplasms of the immune system initially thought to be of T-cell type. Reported is a case of large cell lymphoma with multilobated nuclei in which immunologic marker studies demonstrated that the neoplastic cells had characteristics of B-lympho...

journal_title：Cancer

authors： Parfrey NA,Mann RB,Selonick SE,Beschorner WE

更新日期：1985-05-01 00:00:00

abstract：:The clonal growth pattern of bone marrow and peripheral blood cells from 16 patients with clinically suspected chronic myelogenous leukemia (CML) was evaluated in the double-layer agar system. Cytogenetic studies were performed on parallel marrow and peripheral blood samples. In four cases a unique growth pattern emer...

journal_title：Cancer

authors： Selvaggi S,Wolman SR,Bornstein S,Edinger F

更新日期：1984-12-15 00:00:00

abstract：:Twenty-four patients with metastatic cancer of the choroid were seen in the Department of Therapeutic Radiology, Rush-Presbyterian--St. Luke's Medical Center, Chicago, between 1964 and 1975. One fourth of the patients had involvement in both eyes, for a total of 30 eyes involved with metastatic cancer. The most common...

journal_title：Cancer

authors： Reddy S,Saxena VS,Hendrickson F,Deutsch W

更新日期：1981-02-15 00:00:00

abstract：:Patients with ulcerative colitis are at increased risk of developing adenocarcinoma of the colon. The authors describe a patient whose colonic neoplasm demonstrated histologic characteristics of both an adenocarcinoma and a carcinoid tumor and which was pathologically identical to a appendiceal adenocarcinoid. Because...

journal_title：Cancer

authors： Lyss AP,Thompson JJ,Glick JH

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Overall survival (OS) is considered the gold standard for determining treatment efficacy in oncology trials, but the relation between treatment and OS can be challenging to assess because of long study durations and the impact of subsequent therapies on outcome. Using OS can be particularly difficult for new...

journal_title：Cancer

authors： Smith BD,DeZern AE,Bastian AW,Durie BGM

更新日期：2017-05-15 00:00:00

abstract：BACKGROUND:Ifosfamide has previously been shown to be active as a single agent and in combination with doxorubicin, etoposide, and teniposide in pediatric solid tumors and adult acute leukemia. The authors performed a dose-escalation trial of ifosfamide with a fixed dosage of etoposide, with mesna uroprotection, in chi...

journal_title：Cancer

authors： Bernstein ML,Whitehead VM,Devine S,Grier H,Kung F,Krischer J,Dreyer Z,Bell B,Land V,Buchanan GR

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Sacituzumab govitecan (IMMU-132), an antitrophoblastic cell-surface antigen (anti-Trop-2) humanized antibody-SN-38 conjugate, had encouraging efficacy in the phase 1 clinical trial. This report further examines the pharmacokinetics and safety of multiple cycles of IMMU-132 at doses of 8 or 10 mg/kg in patien...

journal_title：Cancer

authors： Ocean AJ,Starodub AN,Bardia A,Vahdat LT,Isakoff SJ,Guarino M,Messersmith WA,Picozzi VJ,Mayer IA,Wegener WA,Maliakal P,Govindan SV,Sharkey RM,Goldenberg DM

更新日期：2017-10-01 00:00:00

abstract：:In the past all clear cell carcinomas of the female genital tract were thought to arise from mesonephric remnants. Recently increasing evidence has related their origin to müllerian rather than mesonephric epithelium. One of the main reasons that has been advanced to support their mesonephric origin has been their occ...

journal_title：Cancer

authors： Hasumi K,Ehrmann RL

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:We prospectively compared the proxy reporting of health-related quality of life (HRQL) by parents and nurses of children with Hodgkin disease to see how well they correlated with the children's report. METHODS:Children with all stages of Hodgkin disease, their parents, and the clinic nurse were all asked to...

journal_title：Cancer

authors： Klaassen RJ,Barr RD,Hughes J,Rogers P,Anderson R,Grundy P,Ali SK,Yanofsky R,Abla O,Silva M,Carret AS,Cappelli M

更新日期：2010-03-15 00:00:00

abstract：:Three separate histologic types of gastric pseudolymphoma (GPL) are described: (1) the common "inflammatory" type usually accompanied by ulceration and extensive fibrosis; (2) the entity known as "nodular lymphoid hyperplasia," which was associated with multiple intestinal lesions; and (3) the third reported case of a...

journal_title：Cancer

authors： Brooks JJ,Enterline HT

更新日期：1983-02-01 00:00:00

abstract：:This report describes a unique palliative approach of radical surgical debridement for uncontrollable, recurrent pelvic tumors ulcerating through the perineum. All conservative treatment attempts with radiotherapy and chemotherapy had failed. Seven patients have been treated with resection of the tumor including a por...

journal_title：Cancer

authors： Temple WJ,Ketcham AS

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Men who receive androgen-deprivation therapy (ADT) for prostate cancer experience several side effects from this treatment. A few recent studies have examined the cognitive implications of ADT and how they impact a patient's treatment decision-making, occupational pursuits, and quality of life. For this repo...

journal_title：Cancer

authors： Nelson CJ,Lee JS,Gamboa MC,Roth AJ

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Patients scheduled to receive chemotherapy frequently undergo pretherapy dental treatment to eliminate potential sources of odontogenic infection. A prospective study was conducted to assess a new protocol emphasizing minimal pretherapy dental treatment. METHODS:Forty-eight consecutive patients diagnosed wi...

journal_title：Cancer

authors： Toljanic JA,Bedard JF,Larson RA,Fox JP

更新日期：1999-04-15 00:00:00

abstract：:From a total of 874 patients with small cell lung cancer (SCC), a series of 104 patients were reviewed to determine if bone marrow relapses are detectable by routine clinical investigations. Autopsy, including microscopical bone marrow examination, was performed in all the 104 patients and bone metastases were disclos...

journal_title：Cancer

authors： Kristjansen PE,Osterlind K,Hansen M

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND:: Delirium has been the most frequent neuropsychiatric complication in patients with advanced cancer. This exploratory study aimed to determine the proportion of patients who were able to recall their experience of delirium and the level of distress experienced by patients, family caregivers, and healthcare ...

journal_title：Cancer

authors： Bruera E,Bush SH,Willey J,Paraskevopoulos T,Li Z,Palmer JL,Cohen MZ,Sivesind D,Elsayem A

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Differentiating primary glandular from high-grade squamous intraepithelial lesions (HSIL) that involve endocervical glands is not an uncommon diagnostic problem in liquid-based gynecological cytology. Squamous and atypical glandular cell lesions may show similar cytomorphologic features. The aim of this stud...

journal_title：Cancer

authors： Garcia MT,Acar BC,Jorda M,Gomez-Fernandez C,Ganjei-Azar P

更新日期：2007-02-25 00:00:00

abstract：:The study is a clinicopathologic report on 64 patients with primary adenocarcinoma of the urinary bladder and urachus, with particular reference to important prognostic and therapeutic factors. All tumors exhibited adenocarcinomatous features in at least two thirds of the examined tumor area. Pure forms of the differe...

journal_title：Cancer

authors： Anderström C,Johansson SL,von Schultz L

更新日期：1983-10-01 00:00:00

abstract：:Kaposi's sarcoma of the gingiva and skin developed in an HIV-negative renal transplant patient while he was receiving cyclosporine therapy. The Kaposi's sarcoma developed shortly after the patient had an acute infection with cytomegalovirus (CMV). Electron microscopy of the tumor's established cell line showed two typ...

journal_title：Cancer

authors： Siegal B,Levinton-Kriss S,Schiffer A,Sayar J,Engelberg I,Vonsover A,Ramon Y,Rubinstein E

更新日期：1990-02-01 00:00:00

abstract：:The growth rates of recurrent hepatocellular carcinoma (HCC) after orthotopic liver transplantation (OLTX) were estimated by calculating the tumor doubling time (TDT) in 20 patients. The mean TDT, calculated by multiple measurement of tumor size, was 44.3 +/- 11.3 days (mean +/- standard error) in 12 patients with pul...

journal_title：Cancer

authors： Yokoyama I,Carr B,Saitsu H,Iwatsuki S,Starzl TE

更新日期：1991-11-15 00:00:00

abstract：:A specimen from the small intestine with multiple (three) classic carcinoid tumors and one appendiceal carcinoid tumor displaying argentaffinity, argyrophilia (Grimelius stain), and serotonin and neuron specific enolase immunoreactivity was examined by light microscopy with regard to the tumor cell histopathogenesis. ...

journal_title：Cancer

authors： Lundqvist M,Wilander E

更新日期：1987-07-15 00:00:00

abstract：BACKGROUND:An increase in resting energy expenditure (REE) is considered to contribute to the weight loss experienced by patients with cancer. However, alternations in basal metabolism vary among patients with different neoplasms. REE in patients with hepatocellular carcinoma (HCC), a common malignant tumor in Taiwan, ...

journal_title：Cancer

authors： Chen WJ,Chung YC

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Sipuleucel-T is an investigational active cellular immunotherapy product designed to stimulate an immune response against prostate cancer. The safety and efficacy of sipuleucel-T was evaluated in 2 identically designed, randomized, double-blind, placebo-controlled trials (D9901 and D9902A) conducted in men w...

journal_title：Cancer

authors： Higano CS,Schellhammer PF,Small EJ,Burch PA,Nemunaitis J,Yuh L,Provost N,Frohlich MW

更新日期：2009-08-15 00:00:00

abstract：:The role of amsacrine in inducing remission in patients with cardiac disease and acute leukemia was evaluated. There were 17 patients with acute myelogenous leukemia (AML), six with acute lymphocytic leukemia (ALL), and one with biphenotypic leukemia. In this series of 24 patients whose disease had relapsed and who ha...

journal_title：Cancer

authors： Arlin ZA,Feldman EJ,Mittelman A,Ahmed T,Puccio C,Chun HG,Cook P,Baskind P,Marboe C,Mehta R

更新日期：1991-09-15 00:00:00

abstract：:Over the last decade, new cytotoxic treatments and targeted therapies have altered treatment paradigms for patients with metastatic non-small cell lung cancer (NSCLC). We sought to analyze the impact of histology and biomarker selection criteria on outcomes of clinical trials in metastatic NSCLC reported over the last...

journal_title：Cancer

authors： Gentzler RD,Yentz SE,Johnson ML,Rademaker AW,Patel JD

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:Children with average-risk acute lymphoblastic leukemia (AR-ALL) face many challenges that can adversely affect their quality of life (QOL). However, to the authors' knowledge, patterns and predictors of QOL impairment during therapy have not been well characterized to date. METHODS:Patients with AR-ALL who...

journal_title：Cancer

authors： Zheng DJ,Lu X,Schore RJ,Balsamo L,Devidas M,Winick NJ,Raetz EA,Loh ML,Carroll WL,Sung L,Hunger SP,Angiolillo AL,Kadan-Lottick NS

更新日期：2018-02-01 00:00:00

abstract：:There were no significant differences between the mean blood plasma (leukocyte-free) RNAase activity among 128 healthy women volunteers age 13-70 and 49 women with benign gynecological tumors. Exceptions to this finding were three apparently healthy women volunteers who had plasma enzyme activity which was higher than...

journal_title：Cancer

authors： Sheid B,Lu T,Pedrinan L,Nelson JH Jr

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Conflicting results have been obtained regarding blood flow distribution to liver tumors. The emphasis on portal vein perfusion has had a great impact on the design of treatment protocols. METHODS:Double microsphere technique with reference organ sampling was used for the measurement of hepatic artery and p...

journal_title：Cancer

authors： Wang LQ,Persson BG,Bergqvist L,Bengmark S

更新日期：1994-11-01 00:00:00