Adenocarcinoid tumor of the colon arising in preexisting ulcerative colitis.

Abstract:

:Patients with ulcerative colitis are at increased risk of developing adenocarcinoma of the colon. The authors describe a patient whose colonic neoplasm demonstrated histologic characteristics of both an adenocarcinoma and a carcinoid tumor and which was pathologically identical to a appendiceal adenocarcinoid. Because individual tumor cells stained positively for both mucin and argentaffin granules, the histologic picture is unique among the malignancies seen in patients with ulcerative colitis and cannot be explained as a composite of two independent neoplasms that have grown together. Since the tumor discussed seems to have originated from a single cell line, the theory that carcinoids develop from neural crest cells which have migrated to embryonic gut endoderm must be regarded with considerable doubt.

journal_name

Cancer

journal_title

Cancer

authors

Lyss AP,Thompson JJ,Glick JH

doi

10.1002/1097-0142(19810801)48:3<833::aid-cncr28204

subject

Has Abstract

pub_date

1981-08-01 00:00:00

pages

833-9

issue

3

eissn

0008-543X

issn

1097-0142

journal_volume

48

pub_type

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