Abstract:
:Patients with ulcerative colitis are at increased risk of developing adenocarcinoma of the colon. The authors describe a patient whose colonic neoplasm demonstrated histologic characteristics of both an adenocarcinoma and a carcinoid tumor and which was pathologically identical to a appendiceal adenocarcinoid. Because individual tumor cells stained positively for both mucin and argentaffin granules, the histologic picture is unique among the malignancies seen in patients with ulcerative colitis and cannot be explained as a composite of two independent neoplasms that have grown together. Since the tumor discussed seems to have originated from a single cell line, the theory that carcinoids develop from neural crest cells which have migrated to embryonic gut endoderm must be regarded with considerable doubt.
journal_name
Cancerjournal_title
Cancerauthors
Lyss AP,Thompson JJ,Glick JHdoi
10.1002/1097-0142(19810801)48:3<833::aid-cncr28204subject
Has Abstractpub_date
1981-08-01 00:00:00pages
833-9issue
3eissn
0008-543Xissn
1097-0142journal_volume
48pub_type
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