Abstract:
:Pericardial effusion and trifascicular block developed 5 years following mediastinal irradiation for Hodgkin's disease in a 19-year-old patient. Another 24-year-old patients had an acute myocardial infarction followed by severe angina pectoris 5 years following mediastinal irradiation for the same disease. A pericardial window and a permanent demand pacemaker were used in the first case; an aorto-coronary vein grafting was utilized in the second patient. Both patients responded to treatment and are well. Five other previously reported cases of myocardial injury that occurred 2 months to 8 years following mediastinal irradiation in young patients were reviewed. To our knowledge, successful surgical treatment of this disease entity has not been reported before. Close, long-term follow-up of patients who have received mediastinal irradiation should be helpful in the early recognition and successful management of these serious cardiac complications. The systematic clinical and radiographic surveilance of these patients should be supplemented by a routine 12-lead electrocardiogram.
journal_name
Cancerjournal_title
Cancerauthors
Ali MK,Kahlil KG,Fuller LM,Leachman RD,Sullivan MP,Loh KK,Gamble JF,Shullenberger CCdoi
10.1002/1097-0142(197611)38:5<1941::aid-cncr282038subject
Has Abstractpub_date
1976-11-01 00:00:00pages
1941-6issue
5eissn
0008-543Xissn
1097-0142journal_volume
38pub_type
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