Abstract:
:The use of preoperative computed tomographic (CT) scans of the chest in carcinoma of the esophagus to associate preoperative staging with postoperative survival is controversial. Thirty-two patients who underwent esophagectomy and reconstruction were examined with respect to a variety of variables available on preoperative evaluation, including lesion width on CT scan, lesion length on CT scan, and barium esophagogram. Each variable was evaluated for its ability to predict the presence of extraesophageal spread of tumor, as determined pathologically by logistic regression analysis. Lesions greater than 3.0 cm in width by CT scan were associated with a significantly higher incidence of extraesophageal spread. Tumor location, gender, histologic grade, presence of in situ lesions, vascular invasion, eosinophilia, nodal metastases, and preoperative chemotherapy had no predictive value for survival. Duration of survival was affected by the presence of esophageal spread of disease and lesion width. These results indicate that preoperative CT scanning can predict extraesophageal spread of tumor, and this is associated with overall survival.
journal_name
Cancerjournal_title
Cancerauthors
Lefor AT,Merino MM,Steinberg SM,Dwyer A,Roth JA,Flanagan M,Pass HIdoi
10.1002/1097-0142(19881001)62:7<1287::aid-cncr2820subject
Has Abstractpub_date
1988-10-01 00:00:00pages
1287-92issue
7eissn
0008-543Xissn
1097-0142journal_volume
62pub_type
杂志文章相关文献
CANCER文献大全abstract::Forty-six examples of carcinoma cuniculatum, a rare variant of squamous cell carcinoma of the skin, were studied by means of light and electron microscopy and immunoperoxidase techniques. The tumors usually presented as ulcerated, fungating, and polypoid masses with openings of sinus tracts onto the skin surface that ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820601)49:11<2395::aid-cncr282
更新日期:1982-06-01 00:00:00
abstract::A case of an extramedullary intrathoracic plasmacytoma causing superior vena cava syndrome is described. Review of the literature on intrathoracic plasmacytomas and superior vena cava syndrome revealed that no similar cases have been described to date. The initial presentation, management, and response to treatment ar...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19910915)68:6<1376::aid-cncr2820
更新日期:1991-09-15 00:00:00
abstract:BACKGROUND:Axillary dissection in elderly patients with early-stage breast carcinoma who do not have palpable axillary lymph nodes is controversial because of the associated morbidity of the surgery, reduced life expectancy of the patients, and efficacy of hormone therapy in preventing recurrences and axillary events. ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11173
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Previous data from the National Cancer Data Base have examined time trends in stage of disease, treatment patterns, and survival for selected cancers. The most current (1993) data for breast carcinoma are described here. METHODS:Five Calls for Data have yielded a total of 508,724 breast cancer cases diagnos...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19961015)78:8<1838::aid-cn
更新日期:1996-10-15 00:00:00
abstract::Tumor-specific DNA sequences or unique sequences have been found in a number of human cancer cells including gliomas but not in equivalent normal cells. In a continuing effort to further elucidate the nature of these sequences, thermal analysis using the hydroxyapatite technique was carried out on the various grades o...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800715)46:2<303::aid-cncr28204
更新日期:1980-07-15 00:00:00
abstract::Forty-nine patients with regionally confined recurrent malignancy were treated with intra-arterial cis-diamminedichloro platinum II in a Phase I-II trial. A safe starting dose of 120 mg/m2 was established. An overall response rate of 45% was noted with significant responses observed among patients with melanoma, sarco...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800315)45:6<1278::aid-cncr2820
更新日期:1980-03-15 00:00:00
abstract::Twenty-four women with ovarian carcinoma that had metastasized to the liver were treated with intrahepatic infusional therapy. No consistent drug regimen was used. There were no complete responders; however, 33% had a partial response. All responses were noticed after the first course of therapy. The median length of ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870601)59:11<1866::aid-cncr282
更新日期:1987-06-01 00:00:00
abstract::To see whether urine enzyme activities could be used as an index in evaluating the disease status of leukemia patients, we examined the activities of four enzymes: arylsulfatases A(AS-A) and B(AS-B), alkaline phosphatase (AP), and lactate dehydrogenase (LDH). AP and LDH showed no consistent patterns. The activities of...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197909)44:3<873::aid-cncr2820440
更新日期:1979-09-01 00:00:00
abstract:BACKGROUND:The expression of a distinct alpha-3/4-monofucosylated polylactosaminoglycan epitope, which is detected by monoclonal antibody FW6, was investigated by comparative immunohistochemical analysis of colorectal tissue specimens exhibiting different grades of premalignant and malignant transformation. The presenc...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19950915)76:6<954::aid-cncr28207
更新日期:1995-09-15 00:00:00
abstract::Basal cell carcinomas (BCCs) obtained from 22 subjects undergoing microscopically controlled surgery were transplanted to 40 athymic (nude) mice. With no further immunosuppression of the mice, no tumor growth was noted in the first 14 attempts. When mice were further immunosuppressed with anti-lymphocyte serum (ALS) i...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850801)56:3<519::aid-cncr28205
更新日期:1985-08-01 00:00:00
abstract:BACKGROUND:Postchemotherapy surgery is an essential component in the management of patients with metastatic germ cell tumors (GCT). The authors assessed their institutional experience of retroperitoneal lymph node dissection (RPLND) after multiple chemotherapy regimens for advanced GCT. METHODS:By analyzing the instit...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22440
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:Since the 1970s, incidence rates of esophageal and gastric cardia adenocarcinoma have risen substantially. Reasons for the increasing trends are not well understood. METHODS:A population-based, case-control study that included esophageal adenocarcinomas (n = 222), gastric cardia adenocarcinomas (n = 277), d...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11568
更新日期:2003-09-01 00:00:00
abstract::The authors retrospectively reviewed 50 episodes of spinal epidural tumor that occurred in 42 patients with metastatic prostate cancer and were treated with external-beam radiation. Treatment response was evaluated in terms of symptoms, neurologic status, and, in most cases, reduction of tumor on repeat myelography. A...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19921101)70:9<2319::aid-cncr2820
更新日期:1992-11-01 00:00:00
abstract::A simple, fast technique for percutaneous insertion of two single-lumen, large-bore Silastic catheters for long-term venous access is described. Helpful technical points are discussed. Recent experience with insertion of 102 catheters using this technique yielded no major complications. ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850601)55:11<2712::aid-cncr282
更新日期:1985-06-01 00:00:00
abstract::A brother and sister with Fanconi's anemia, having typical skeletal deformity and characteristic chromosomal breaks in their lymphocytes and who followed the typical clinical course, with progressive bone marrow insufficiency beginning late in the first decade, are described. The natural history of the disease before ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19841101)54:9<1850::aid-cncr2820
更新日期:1984-11-01 00:00:00
abstract:BACKGROUND:Gastrin-releasing peptide (GRP) is an autocrine growth factor in patients with small cell lung carcinoma (SCLC). The authors developed a reverse transcriptase-polymerase chain reaction (RT-PCR) assay for the detection of SCLC cells in the peripheral blood and the pleural effusion using preproGRP mRNA as a ta...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11378
更新日期:2003-05-15 00:00:00
abstract::Stage IV-S neuroblastoma is a unique disseminated neoplasia characterized by remote disease to the liver, skin, or bone marrow. Stage IV-S patients have frequent spontaneous remissions and a 60% to 90% survival rate. Many investigators have recommended minimal or no therapeutic intervention; however, some patients do ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860715)58:2<372::aid-cncr28205
更新日期:1986-07-15 00:00:00
abstract::Characteristic alterations of marker enzymes and tumor-associated antigens have been detected in the preneoplastic lesions of experimental hepatocarcinogenesis. An identical pattern of enzyme activity (increased gammaglutamyl transferase, loss of glucose-6-phosphatase, and canalicular adenosine triphosphatase) was dem...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810401)47:7<1796::aid-cncr2820
更新日期:1981-04-01 00:00:00
abstract:BACKGROUND:The current study sought to delineate prospectively the rates and clinical course of emotional distress, cognitive impairment, and quality of life (QOL) in chemotherapy-naive patients with cancer and to consider the determinants of global QOL. METHODS:Patients who consented to participate were administered ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20385
更新日期:2004-07-15 00:00:00
abstract:BACKGROUND:Menorrhagia is a serious complication in young female oncology patients who suffer from severe thrombocytopenia during myelosuppressive treatment. To the authors' knowledge, little is known regarding the incidence of this complication or the effectiveness of possible therapies for its prevention. METHODS:In...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22199
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:In less than a century, lung cancer has progressed from a medical curiosity to the most deadly of all malignant diseases on our planet. Because cigarette smoking is responsible for the existing global lung cancer epidemic, policy initiatives have focused almost exclusively on primary prevention. There is no ...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(20001201)89:11+<2422::aid-cncr16
更新日期:2000-12-01 00:00:00
abstract::Among 164 patients with acute lymphoblastic leukemia (ALL) (age greater than 11 years) induced into complete remission at four hospitals in Italy and The Netherlands between 1971-1977, 49 survived for more than three years in continuous complete remission. Features at diagnosis of the 49 long-term survivors were compa...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830701)52:1<30::aid-cncr282052
更新日期:1983-07-01 00:00:00
abstract:BACKGROUND:In this report, the authors present the results from a study of patients with unresectable oropharyngeal squamous cell carcinomas who were treated on a protocol of hyperfractionated radiation and high-dose intraarterial cisplatin (HYPERRADPLAT) at the University of Kentucky. METHODS:The study was designed a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21368
更新日期:2005-10-15 00:00:00
abstract::Necropsy and clinical data show that primary hepatocellular carcinoma (PHC) is the commonest cancer among the Senoi (a Malaysian aboringine group). The other aboringine tribes do not appear to have this high predilection for liver cancer. In the necropsy series, PHS was present in 10 out of 22 Senoi patients with cirr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197710)40:4<1618::aid-cncr282040
更新日期:1977-10-01 00:00:00
abstract:BACKGROUND:The value of ultrasound-guided fine-needle aspiration cytology (FNAC) in the diagnosis of nonpalpable breast lesions remains a subject of debate. To determine the accuracy of this procedure in these lesions, a comparative analysis with open surgical biopsy in 188 patients was performed. METHODS:Six hundred ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0142(19980225)84:1<36::aid-cncr
更新日期:1998-02-25 00:00:00
abstract::Based on experience with three cases of endobronchial non-Hodgkin's lymphoma and a review of cases previously reported, two patterns of lymphomatous involvement of airways are described. The Type 1 pattern is characterized by diffuse submucosal infiltrates occurring in the presence of intra- and extrathoracic lymphoma...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860501)57:9<1750::aid-cncr2820
更新日期:1986-05-01 00:00:00
abstract::Plasma carcinoembryonic antigen (CEA) levels were studied in all available members of 17 families in which a presumed sporadic retinoblastoma had occurred. In 9 of the 17 families, close relatives of the patient had elevated CEA levels in the absence of demonstrable disease; this we have termed the "CEA family syndrom...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197603)37:3<1397::aid-cncr282037
更新日期:1976-03-01 00:00:00
abstract::Four cases of an ulcero-proliferative lesion of putative histiocytic origin, arising in the oral cavity, are described. This lesion, which has not been defined previously, is easily confused histologically with a malignant process of lymphoid origin, thereby representing a pseudolymphomatous proliferation. Light micro...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850415)55:8<1722::aid-cncr2820
更新日期:1985-04-15 00:00:00
abstract:BACKGROUND:Bortezomib has preclinical and clinical in B-cell lymphomas, both alone and in combination with other agents. A phase 1 evaluation was conducted of bortezomib with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in patients with untreated diffuse large B-cell lymphoma (DLBC...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25509
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Cancer clinicians do not receive routine training in the psychosocial aspects of patient care such as how to communicate bad news or respond to patients who have unrealistic expectations of cure. Postgraduate workshops may be an effective way to increase interpersonal skills in managing these stressful patie...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00