Computerized tomographic prediction of extraluminal spread and prognostic implications of lesion width in esophageal carcinoma.

Abstract:

:The use of preoperative computed tomographic (CT) scans of the chest in carcinoma of the esophagus to associate preoperative staging with postoperative survival is controversial. Thirty-two patients who underwent esophagectomy and reconstruction were examined with respect to a variety of variables available on preoperative evaluation, including lesion width on CT scan, lesion length on CT scan, and barium esophagogram. Each variable was evaluated for its ability to predict the presence of extraesophageal spread of tumor, as determined pathologically by logistic regression analysis. Lesions greater than 3.0 cm in width by CT scan were associated with a significantly higher incidence of extraesophageal spread. Tumor location, gender, histologic grade, presence of in situ lesions, vascular invasion, eosinophilia, nodal metastases, and preoperative chemotherapy had no predictive value for survival. Duration of survival was affected by the presence of esophageal spread of disease and lesion width. These results indicate that preoperative CT scanning can predict extraesophageal spread of tumor, and this is associated with overall survival.

journal_name

Cancer

journal_title

Cancer

authors

Lefor AT,Merino MM,Steinberg SM,Dwyer A,Roth JA,Flanagan M,Pass HI

doi

10.1002/1097-0142(19881001)62:7<1287::aid-cncr2820

subject

Has Abstract

pub_date

1988-10-01 00:00:00

pages

1287-92

issue

7

eissn

0008-543X

issn

1097-0142

journal_volume

62

pub_type

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