Atypical histiocytic granuloma. Light microscopic, ultrastructural, and histochemical findings in an unusual pseudomalignant reactive lesion of the oral cavity.

Abstract:

:Four cases of an ulcero-proliferative lesion of putative histiocytic origin, arising in the oral cavity, are described. This lesion, which has not been defined previously, is easily confused histologically with a malignant process of lymphoid origin, thereby representing a pseudolymphomatous proliferation. Light microscopic, ultrastructural, and histochemical characteristics including immunoglobulin negativity, positive esterase reactivity, and positive peanut lectin binding support a histiocytic origin. These lesions are not associated with systemic disease or dissemination and heal spontaneously despite their worrisome microscopic appearance.

journal_name

Cancer

journal_title

Cancer

authors

Eversole LR,Leider AS,Jacobsen PL,Kidd PM

doi

10.1002/1097-0142(19850415)55:8<1722::aid-cncr2820

subject

Has Abstract

pub_date

1985-04-15 00:00:00

pages

1722-9

issue

8

eissn

0008-543X

issn

1097-0142

journal_volume

55

pub_type

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