Phase I-II trial of percutaneous intra-arterial cis-diamminedichloro platinum (II) for regionally confined malignancy.

abstract：:A case of Turcot's syndrome (colonic polyposis plus a malignant central nervous system tumor) occurring in a kindred with autosomal dominant colonic polyposis is presented. It is proposed that Turcot's syndrome patients can be classified into Type I where only siblings are affected and Type II where two or more genera...

journal_title：Cancer

authors： Lewis JH,Ginsberg AL,Toomey KE

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:It is well established that prenatal biologic processes are important for the development of some childhood cancers, whereas less is known regarding their influence on adult cancer risk. High birth weight has been associated with risk of breast cancer, whereas studies of other specific cancers and all cancer...

journal_title：Cancer

authors： Ahlgren M,Wohlfahrt J,Olsen LW,Sørensen TI,Melbye M

更新日期：2007-07-15 00:00:00

abstract：BACKGROUND:Fas (CD95/APO-1) and Fas ligand (FasL) play key roles in immunologic homeostasis and immune privilege and may regulate normal cell turnover. Earlier studies had suggested that FasL-positive pancreatic carcinoma cell lines can induce apoptosis in T cells, thereby evading host immune surveillance. In the curre...

journal_title：Cancer

authors： Bernstorff WV,Glickman JN,Odze RD,Farraye FA,Joo HG,Goedegebuure PS,Eberlein TJ

更新日期：2002-05-15 00:00:00

abstract：:To additionally understand the molecular mechanisms and biologic indicators of colonic tumorigenesis through the adenoma-carcinoma sequence, protein kinase C (PKC) activity was examined in the cytosol and particulate fraction of specimen homogenates from 18 human colonic carcinomas and seven coexisting colonic adenoma...

journal_title：Cancer

authors： Kusunoki M,Sakanoue Y,Hatada T,Yanagi H,Yamamura T,Utsunomiya J

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Stenotrophomonas maltophilia is responsible for an increasing number of infections, especially in hospitalized patients. Therapy options are limited and trimethoprim/sulfamethoxazole (TMP/SMX) is often the main treatment option for this infection. In the current study, the risk factors were determined for th...

journal_title：Cancer

authors： Ansari SR,Hanna H,Hachem R,Jiang Y,Rolston K,Raad I

更新日期：2007-06-15 00:00:00

abstract：:A patient is described in whom the first recurrence of a cloacogenic carcinoma of the rectum was an intrahepatic metastasis associated with an hepatic abscess caused by the anaerobic bacterium Peptococcus prevotii. Three previously reported cases of infection associated with hepatic tumor nodules have been found in wh...

journal_title：Cancer

authors： Trump DL,Fahnestock R,Cloutier CT,Dickman MD

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Bisphosphonates currently are the most important class of antiresorptive agents used in the treatment of metabolic bone diseases, including tumor-associated osteolysis and hypercalcemia, Paget's disease, and osteoporosis. These compounds have high affinity for calcium and therefore target to bone mineral, wh...

journal_title：Cancer

authors： Rogers MJ,Gordon S,Benford HL,Coxon FP,Luckman SP,Monkkonen J,Frith JC

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND:Angiogenesis in individuals with various solid tumors has provided useful information on tumor progression and prognosis, and many examples of mast cell (MC) accumulation coupled with angiogenesis can be found in the literature. METHODS:Utilizing monoclonal antibodies for tryptase that are specific markers ...

journal_title：Cancer

authors： Takanami I,Takeuchi K,Naruke M

更新日期：2000-06-15 00:00:00

abstract：:The prognostic significance of ploidy level was studied in prostatic carcinoma and compared with the prognostic significance of morphologic grade and clinical stage. A nonselected group of 145 patients was studied in whom prostatic carcinoma was diagnosed by fine-needle aspiration biopsy at the Karolinska Hospital in ...

journal_title：Cancer

authors： Forsslund G,Esposti PL,Nilsson B,Zetterberg A

更新日期：1992-03-15 00:00:00

abstract：BACKGROUND:Local recurrence is the most frequent site of failure after resection for pancreatic cancer. Tolerance, local control, and survival obtained by the association of resection and intraoperative radiation therapy (IORT) were reported. METHODS:Between June 1985 and March 1993, 90 resections for pancreatic cance...

journal_title：Cancer

authors： Zerbi A,Fossati V,Parolini D,Carlucci M,Balzano G,Bordogna G,Staudacher C,Di Carlo V

更新日期：1994-06-15 00:00:00

abstract：:There are three principal disturbances in bone remodelling that occur in neoplasia affecting the skeleton. The first is an increase in bone turnover that in solid tumors may be confined to sites of metastases or be a generalized phenomenon, most likely related to the secretion of parathyroid hormone-related protein. I...

journal_title：Cancer

authors： Kanis JA,McCloskey EV

更新日期：1997-10-15 00:00:00

abstract：:A simple, fast technique for percutaneous insertion of two single-lumen, large-bore Silastic catheters for long-term venous access is described. Helpful technical points are discussed. Recent experience with insertion of 102 catheters using this technique yielded no major complications. ...

journal_title：Cancer

authors： Carroll C,Sarr MG,Stewart JR

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:Several pathologic staging systems for malignant pleural mesothelioma (MPM) have been published, but none of them provide optimal survival stratification or stage distribution among patients treated with surgery. Interpretation of prior studies that correlate pathologic factors with outcome has been confound...

journal_title：Cancer

authors： Richards WG,Godleski JJ,Yeap BY,Corson JM,Chirieac LR,Zellos L,Mujoomdar A,Jaklitsch MT,Bueno R,Sugarbaker DJ

更新日期：2010-03-15 00:00:00

abstract：BACKGROUND:The recommended phase 2 dose (RP2D) of anticancer agents is determined traditionally by dose-limiting toxicities. Nontoxicity or biological endpoints such as pharmacokinetics, pharmacodynamics, and efficacy can also be used to identify RP2D, which may be relevant to molecularly targeted agents (MTAs). METHO...

journal_title：Cancer

authors： Hansen AR,Cook N,Amir E,Siu LL,Abdul Razak AR

更新日期：2017-04-15 00:00:00

abstract：:The cases of three patients with primary carcinoid tumor of the testis were reported. The patients were 41, 44, and 83 years of age. At initial examination, all three had testicular masses with or without associated pain, and none had the carcinoid syndrome. The tumors measured 4.3 cm, 3.0 cm, and 6.5 cm in dimension....

journal_title：Cancer

authors： Zavala-Pompa A,Ro JY,el-Naggar A,Ordóñez NG,Amin MB,Pierce PD,Ayala AG

更新日期：1993-09-01 00:00:00

abstract：:Indomethacin (prostaglandin synthetase inhibitor) was found to be capable of enhancing the mitogen-induced lymphocyte proliferative responses of healthy subjects and patients with lung cancer. A whole-blood culture technique was used. Indomethacin had no mitogenic activity. We observed a greater enhancement of lymphoc...

journal_title：Cancer

authors： Han T,Takita H

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:The authors evaluated the role of 5-aminolevulinic acid (5-ALA)-induced fluorescence endoscopy (AFE) in the detection of flat urothelial lesions in light of the suggestions made for flat neoplastic lesions within the 1999 World Health Organization (WHO) classification of urinary bladder tumors. METHODS:From...

journal_title：Cancer

authors： Zaak D,Hungerhuber E,Schneede P,Stepp H,Frimberger D,Corvin S,Schmeller N,Kriegmair M,Hofstetter A,Knuechel R

更新日期：2002-09-15 00:00:00

abstract：BACKGROUND:Although aging is one of the most important risk factors for cancer, elderly patients tend to be excluded from cancer clinical trials, only on the basis of chronologic age. Performance Status (PS) has been used widely to select adult patients for entry into clinical trials, but it does not include a comprehe...

journal_title：Cancer

authors： Monfardini S,Ferrucci L,Fratino L,del Lungo I,Serraino D,Zagonel V

更新日期：1996-01-15 00:00:00

abstract：:A case is reported of a patient with pancreatic carcinoma who developed pancreatic ascites after intraoperative fine-needle aspiration cytology (FNAC) biopsy. This complication of FNAC has not previously been reported to the authors' knowledge. The literature is reviewed, and FNAC is shown to be the safest method of p...

journal_title：Cancer

authors： Rosenbaum DA,Frost DB

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Overall, cervical cancer survival in the United States has been reported to be among the highest in the world, despite slight decreases over the last decade. Objective of the current study was to describe cervical cancer survival trends among US women and examine differences by race and stage. METHODS:This ...

journal_title：Cancer

authors： Benard VB,Watson M,Saraiya M,Harewood R,Townsend JS,Stroup AM,Weir HK,Allemani C

更新日期：2017-12-15 00:00:00

abstract：:The effects of radiotherapy on immune status in patients with localized carcinoma of the cervix have been assessed serially up to 5 years remission by a wide range of methods. Neutrophil function and serum immunoglobulins were essentially normal throughout. Peripheral blood neutrophil and lymphocyte counts and the pro...

journal_title：Cancer

authors： Hancock BW,Bruce L,Whitham MD,Ward AM

更新日期：1984-02-15 00:00:00

abstract：:For men diagnosed with clinically localized prostate cancer, definitive therapy with radical prostatectomy, external beam radiation therapy, or brachytherapy offers a high chance of cure. Currently, there are insufficient data to recommend 1 treatment approach over another, leaving physicians and patients to decide ba...

journal_title：Cancer

authors： Nguyen CT,Zelefsky MJ,Kattan MW

更新日期：2009-07-01 00:00:00

abstract：:Fifty-eight patients with 62 pathologic fractures secondary to metastatic disease were admitted to a rehabilitation hospital during a 5-year period. Thirty-four patients were discharged home, 7 were transferred to other facilities, and 17 died. The average hospital stay for the patients who went home (37 days) was onl...

journal_title：Cancer

authors： Bunting RW,Boublik M,Blevins FT,Dame CC,Ford LA,Lavine LS

更新日期：1992-01-01 00:00:00

abstract：:Two human Burkitt's lymphoma cell lines (HBL-4 and HBL-5) were established individually from two patients with small noncleaved cell lymphoma (Burkitt's type). The HBL-4 cell line is Epstein-Barr virus (EBV)-negative, and the HBL-5 cell line is EBV-positive. Cytogenetically, both cell lines had the same chromosomal tr...

journal_title：Cancer

authors： Abe M,Tasaki K,Tominaga K,Fukuhara S,Imai S,Osato T,Wakasa H

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Pericolorectal tumor deposits (TDs) are associated with adverse outcomes in patients with colorectal cancer, and the seventh edition of the American Joint Committee on Cancer (AJCC) staging system recently classified TDs without regional lymph node metastasis as category N1c. However, the definition of TDs h...

journal_title：Cancer

authors： Song JS,Chang HJ,Kim DY,Kim SY,Baek JY,Park JW,Park SC,Choi HS,Oh JH

更新日期：2011-09-01 00:00:00

abstract：:This study examines the interrelationships of depth of penetration, tumor size, and the number of positive nodes in Dukes C colorectal cancer. The results indicated that depth of tumor penetration was related to both tumor size and the number of positive regional lymph nodes. Tumors with positive nodes which failed to...

journal_title：Cancer

authors： Wolmark N,Fisher ER,Wieand HS,Fisher B

更新日期：1984-06-15 00:00:00

abstract：:The majority of patients with advanced ovarian cancer progress after first-line therapy and require further treatment. Tumor biology, prior chemotherapy, responses to previous therapy, performance status, and toxicity are the characteristics that influence treatment choice. These criteria have been linked to the time ...

journal_title：Cancer

authors： Pignata S,Pisano C,Di Napoli M,Cecere SC,Tambaro R,Attademo L

更新日期：2019-12-15 00:00:00

abstract：:It is rare for small lymphocytic B-cell malignancies to be associated with osteolytic bone lesions and/or hypercalcemia. The authors present an unusual case of well-differentiated lymphocytic lymphoma (DWDL) in a 70-year-old man who had osteolytic bone lesions and subsequently developed severe refractory hypercalcemia...

journal_title：Cancer

authors： Abboud SL,Gordeuk V,Schacter LP,Crum ED,Spitzer TR

更新日期：1985-11-15 00:00:00

abstract：BACKGROUND:: Patients with oral premalignant lesions (OPL) present with oral squamous cell carcinomas (OSCC) at a much higher rate than the general population. There are currently no useful markers that indicate specifically which OPLs are most likely to progress. Three small integrin binding ligands N-linked glycoprot...

journal_title：Cancer

authors： Ogbureke KU,Abdelsayed RA,Kushner H,Li L,Fisher LW

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the impact of a prostate-specific antigen (PSA) complete response (PSA-CR), measured at the end of external-beam radiotherapy and short-term hormone therapy, on treatment outcomes. METHODS:The phase 3 Radiation Therapy Oncology Group 9413 trial, as part of its origi...

journal_title：Cancer

authors： Cury FL,Hunt D,Roach M 3rd,Shipley W,Gore E,Hsu IC,Krisch RE,Seider MJ,Sandler H,Lawton C

更新日期：2013-06-01 00:00:00