Protein kinase C activity in human colonic adenoma and colorectal carcinoma.

abstract：BACKGROUND:Little is understood about the factors that influence survival in patients who undergo gamma-knife stereotactic radiosurgery (SRS) for brain metastases. METHODS:Demographic, disease, treatment, and survival data on 334 patients with intracranial metastases who underwent initial SRS from 1998 to 2004 were ab...

journal_title：Cancer

authors： DiLuna ML,King JT Jr,Knisely JP,Chiang VL

更新日期：2007-01-01 00:00:00

abstract：:Eighteen patients with unresectable ductal adenocarcinoma of the pancreas received definitive, high-dose, small-volume radiation therapy. All patients had at least one laparotomy, at which time a biopsy was obtained, radio-opaque clips were placed to define the extent of the gross tumor, and usually some form of bypas...

journal_title：Cancer

authors： Dobelbower RR Jr,Borgelt BB,Suntharalingam N,Strubler KA

更新日期：1978-03-01 00:00:00

abstract：:109 cases of breast cancer were treated by tumorectomy and radiotherapy or radiotherapy alone. Almost 30% with small tumors (T1, T2) were considered inoperable for medical reasons and 70% refused mastectomy. Over the past five years the number of patients refusing mastectomy has definitely increased. 59 cases of surgi...

journal_title：Cancer

authors： Alpert S,Ghossein NA,Stacey P,Migliorelli FA,Efron G,Krishnaswamy V

更新日期：1978-10-01 00:00:00

abstract：:Necropsy and clinical data show that primary hepatocellular carcinoma (PHC) is the commonest cancer among the Senoi (a Malaysian aboringine group). The other aboringine tribes do not appear to have this high predilection for liver cancer. In the necropsy series, PHS was present in 10 out of 22 Senoi patients with cirr...

journal_title：Cancer

authors： Sumithran E,Prathap K

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Cisplatin has been reported to enhance the cell-killing effect of radiation. The current study was conducted to evaluate the efficacy and toxicity of radiotherapy combined with cisplatin in patients with locally advanced pancreatic carcinoma. METHODS:Forty-one patients with pancreatic carcinoma that was unr...

journal_title：Cancer

authors： Okusaka T,Okada S,Tokuuye K,Wakasugi H,Saisho H,Ishikawa O,Matsuno S,Sato T,Sato K,Non-surgical Treatment Group for Pancreatic Cancer in Japan.

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Immunohistological markers specific for a single type of epithelium are rare. Recently, urothelium tissue-specific genes were cloned. The genes encoded a family of transmembrane proteins, uroplakins, that are expressed only in urothelial mucosa. Using uroplakin antibodies on paraffin-embedded tissue, a previ...

journal_title：Cancer

authors： Xu X,Sun TT,Gupta PK,Zhang P,Nasuti JF

更新日期：2001-06-25 00:00:00

abstract：BACKGROUND:We prospectively compared the proxy reporting of health-related quality of life (HRQL) by parents and nurses of children with Hodgkin disease to see how well they correlated with the children's report. METHODS:Children with all stages of Hodgkin disease, their parents, and the clinic nurse were all asked to...

journal_title：Cancer

authors： Klaassen RJ,Barr RD,Hughes J,Rogers P,Anderson R,Grundy P,Ali SK,Yanofsky R,Abla O,Silva M,Carret AS,Cappelli M

更新日期：2010-03-15 00:00:00

abstract：:The report describes a clinical trial on conservative surgery in progress at the National Cancer Institute of Milan, Italy. The randomized clinical trial compares radical mastectomy with a more conservative procedure consisting of mammary resection plus axillary dissection plus radiotherapy. The resection comprises an...

journal_title：Cancer

authors： Veronesi U,Banfi A,Saccozzi R,Salvadori B,Zucali R,Uslenghi C,Greco M,Luini A,Rilke F,Sultan L

更新日期：1977-06-01 00:00:00

abstract：:Prostatic intra-epithelial neoplasia (PIN, or intraductal dysplasia) is considered a precursor of invasive carcinoma, characterized by proliferation and anaplasia of cells lining prostatic ducts and acini. The highest grade of PIN, Grade 3, is thought to represent carcinoma in situ. To quantitate the degree of disrupt...

journal_title：Cancer

authors： Bostwick DG,Brawer MK

更新日期：1987-02-15 00:00:00

abstract：:Vitamin B6 is involved in many biological processes of potential relevance to carcinogenesis and tumor growth, including DNA synthesis and maintenance of immunocompetence, yet very little information exists on B6 nutritional status in childhood leukemia. Using a radioenzymatic assay, the authors measured plasma pyrido...

journal_title：Cancer

authors： Pais RC,Vanous E,Hollins B,Faraj BA,Davis R,Camp VM,Ragab AH

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Lymphedema of the arm is a serious consequence of breast carcinoma treatment. Postmastectomy lymphedema of the upper limb usually is related to certain risk factors such as axillary surgery, radiotherapy, obesity, venous outflow obstruction, delayed wound healing, and infection. The objective of the current ...

journal_title：Cancer

authors： Herd-Smith A,Russo A,Muraca MG,Del Turco MR,Cardona G

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Long-term survivors of testicular cancer (TC) who received cisplatin-based chemotherapy have an increased risk of cardiovascular disease. A cross-sectional study was performed to objectively assess cardiovascular risk, subclinical atherosclerosis, and endothelial function in long-term survivors of TC. METHO...

journal_title：Cancer

authors： Vaughn DJ,Palmer SC,Carver JR,Jacobs LA,Mohler ER

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Lung cancer (LC) is the most common fatal malignancy, but there are no useful tumor markers for diagnosis or monitoring. Mucin 1 has an established role as a marker in other malignancies, but has undergone limited assessment in LC. METHODS:Serum from 86 patients with LC and 24 with benign pulmonary disease ...

journal_title：Cancer

authors： Willsher PC,Xing PX,Clarke CP,Ho DW,McKenzie IF

更新日期：1993-11-15 00:00:00

abstract：:The current study was undertaken to reevaluate the histogenesis of adenomatoid tumor by an immunoperoxidase method of detecting factor VIII related antigen, a tissue specific marker for vascular endothelium. Three of eight adenomatoid tumors showed diffuse cytoplasmic staining of the cells lining the lumina. When thes...

journal_title：Cancer

authors： Bell DA,Flotte TJ

更新日期：1982-09-01 00:00:00

abstract：:Eight cases of primary non-Hodgkin's lymphoma of the breast found in the pathology files of the Institute of Oncology, Ljubljana, Yugoslavia, for a period of 25 years (from 1961 to 1985) were analyzed. During the same period 5711 cases of breast carcinoma were seen. Seven cases were diffuse lymphomas, and one case was...

journal_title：Cancer

authors： Lamovec J,Jancar J

更新日期：1987-12-15 00:00:00

abstract：BACKGROUND:Although flow cytometry (FCM) has become a widely used technique for the measurement of DNA content in solid tumors, the correlation of ploidy analysis by FCM with cytogenetic analysis (CGA) is not well described. The sensitivities of G-banded CGA and FCM were compared to determine the accuracy of the DNA in...

journal_title：Cancer

authors： Dressler LG,Duncan MH,Varsa EE,McConnell TS

更新日期：1993-09-15 00:00:00

abstract：BACKGROUND:Periosteal osteosarcoma is a rare variant of osteosarcoma. Wide surgical removal is the mainstay of treatment, but controversy remains about the role of chemotherapy. The objective of this study was to review and analyze the clinical and treatment-related factors that influence the survival of patients with ...

journal_title：Cancer

authors： Cesari M,Alberghini M,Vanel D,Palmerini E,Staals EL,Longhi A,Abate M,Ferrari C,Balladelli A,Ferrari S

更新日期：2011-04-15 00:00:00

abstract：:Carcinoembryonic antigen (CEA) was measured in extracts of cell suspensions from tumors of the colon, stomach, breast, lung and kidney. Cell suspensions were also obtained from normal tissue surrounding the primary tumors. The number of neoplastic cells in each cell suspension was determined by cytologic criteria. Hig...

journal_title：Cancer

authors： MacSween JM,Anderson GH

更新日期：1977-08-01 00:00:00

abstract：:A series of 108 prospectively collected human pancreata were evaluated histologically for the presence of acinar cell and ductal lesions. Foci of dysplastic acinar cells were present in 44% of the series. Some of the focal acinar cell abnormalities were similar to atypical acinar cell nodules which have been described...

journal_title：Cancer

authors： Longnecker DS,Shinozuka H,Dekker A

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:The authors conducted this study to update their experience with patients who have ovarian serous borderline tumors with noninvasive peritoneal implants, with the objectives of gaining additional insight into the biologic behavior of these tumors and understanding better the effects of postoperative treatmen...

journal_title：Cancer

authors： Gershenson DM,Silva EG,Tortolero-Luna G,Levenback C,Morris M,Tornos C

更新日期：1998-11-15 00:00:00

abstract：BACKGROUND:The current study was conducted to assess the efficacy and toxicity of sorafenib as front-line therapy in patients with stage IIIB (pleural effusion) or IV nonsmall cell lung cancer (NSCLC). METHODS:Patients received sorafenib 400 mg twice daily by mouth continuously, and were evaluated every 2 weeks during...

journal_title：Cancer

authors： Dy GK,Hillman SL,Rowland KM Jr,Molina JR,Steen PD,Wender DB,Nair S,Mandrekar S,Schild SE,Adjei AA,North Central Cancer Treatment Group Study N0326.

更新日期：2010-12-15 00:00:00

abstract：BACKGROUND:The therapeutic impact of tumor resection is poorly defined. Therefore the current study was conducted. METHODS:A retrospective, 2-institutional study was conducted (1991-1994) to compare the treatment results of stereotactic biopsy plus radiation therapy (99 patients; tumor dose: 60 gray [Gy]) with those o...

journal_title：Cancer

authors： Kreth FW,Berlis A,Spiropoulou V,Faist M,Scheremet R,Rossner R,Volk B,Ostertag CB

更新日期：1999-11-15 00:00:00

abstract：BACKGROUND:Despite an increasing interest in the clinical application of positron emission tomography (PET) in tumors of the adult patient as a diagnostic and prognostic tool, only a few studies have been concerned with the usefulness of PET with [18F]2-deoxy-2-fluoro-D-glucose (FDG) in childhood tumors. METHODS:Fifte...

journal_title：Cancer

authors： Holthoff VA,Herholz K,Berthold F,Widemann B,Schröder R,Neubauer I,Heiss WD

更新日期：1993-08-15 00:00:00

abstract：:Data from a hospital-based case-control study between 1985-1990 were used to examine the effects of tobacco, alcohol, asbestos, and other occupational exposures on laryngeal cancer risk in 194 white men with primary cancer of the larynx and 184 age-matched control subjects. A dose-dependent effect for current cigarett...

journal_title：Cancer

authors： Muscat JE,Wynder EL

更新日期：1992-05-01 00:00:00

abstract：:This article reviews the clinicopathologic features and the biological behavior of 24 cases of synovial sarcoma that took origin from the cervical prevertebral connective tissue space and manifested as a retropharyngeal tumor or as a palpable mass in the anterior or posterior cervical triangle. The age of the 24 patie...

journal_title：Cancer

authors： Roth JA,Enzinger FM,Tannenbaum M

更新日期：1975-04-01 00:00:00

abstract：:Randomized breast cancer screening trials are helpful in establishing evidence of benefit when they yield statistically significant results. The results of individual randomized screening trials can vary greatly depending on the quality of the images, the frequency of screening, compliance, contamination, sample size,...

journal_title：Cancer

authors： Smart CR

更新日期：1994-07-01 00:00:00

abstract：:During the period from September, 1976 to June, 1979, 70 patients with locoregional or extensive epidermoid carcinoma of the esophagus were treated with the two-drug combination of cisplatin and bleomycin (DB). For the 43 patients with locoregional disease (LRD), DB was used prior to surgery and/or radiation therapy; ...

journal_title：Cancer

authors： Coonley CJ,Bains M,Hilaris B,Chapman R,Kelsen DP

更新日期：1984-12-01 00:00:00

abstract：:The authors evaluated specific gamma-GTP isoenzyme (specific gamma-GTP) found in sera of patients with hepatocellular carcinoma (HCC). In addition to band II and II' which had been reported in our previous publication, band I' also had a high specificity for HCC. One or more of these bands were detectable in 109 (55%)...

journal_title：Cancer

authors： Sawabu N,Nakagen M,Ozaki K,Wakabayashi T,Toya D,Hattori N,Ishii M

更新日期：1983-01-15 00:00:00

abstract：BACKGROUND:Poor prognosis of Stage IV breast cancer patients have at best a 10% 3-year survival rate with conventional chemotherapy. Dose-intensive chemotherapy improved survival rates for some of these patients. METHODS:All patients were Stage IV estrogen receptor-negative or estrogen receptor-positive hormonal refra...

journal_title：Cancer

authors： Dunphy FR,Spitzer G,Fornoff JE,Yau JC,Huan SD,Dicke KA,Buzdar AU,Hortobagyi GN

更新日期：1994-04-15 00:00:00

abstract：BACKGROUND:Sipuleucel-T is an investigational active cellular immunotherapy product designed to stimulate an immune response against prostate cancer. The safety and efficacy of sipuleucel-T was evaluated in 2 identically designed, randomized, double-blind, placebo-controlled trials (D9901 and D9902A) conducted in men w...

journal_title：Cancer

authors： Higano CS,Schellhammer PF,Small EJ,Burch PA,Nemunaitis J,Yuh L,Provost N,Frohlich MW

更新日期：2009-08-15 00:00:00