Abstract:
:A series of 108 prospectively collected human pancreata were evaluated histologically for the presence of acinar cell and ductal lesions. Foci of dysplastic acinar cells were present in 44% of the series. Some of the focal acinar cell abnormalities were similar to atypical acinar cell nodules which have been described in carcinogen-treated experimental animals. The incidence of nodules was higher among patients with a history of heavy cigarette smoking than among nonsmokers, and among patients with a history of alcohol abuse than among abstainers. The presence of dysplastic acinar cell nodules in a pancreas seemed unrelated to the presence of cancer in other sites, or diabetes. Ductal epithelial abnormalities were more frequent than focal acinar cell dysplasia.
journal_name
Cancerjournal_title
Cancerauthors
Longnecker DS,Shinozuka H,Dekker Adoi
10.1002/1097-0142(19800201)45:3<534::aid-cncr28204subject
Has Abstractpub_date
1980-02-01 00:00:00pages
534-40issue
3eissn
0008-543Xissn
1097-0142journal_volume
45pub_type
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