Abstract:
:The current study was undertaken to reevaluate the histogenesis of adenomatoid tumor by an immunoperoxidase method of detecting factor VIII related antigen, a tissue specific marker for vascular endothelium. Three of eight adenomatoid tumors showed diffuse cytoplasmic staining of the cells lining the lumina. When these results were correlated with the light and electron microscopy, it was found that there were two distinct groups of tumors. The vascular adenomatoid tumors stained positively for factor VIII related antigen and did not have tumor cells between tubules. The mesothelial adenomatoid tumor did not stain for factor VIII related antigen, had individual and solid nests of tumor cells between the tubules and had mesothelial characteristics on electron microscopy. These results strongly suggest that adenomatoid tumors can be subdivided into tumors of either mesothelial or vascular endothelial origin, and that these two groups can be distinguished on light microscopy.
journal_name
Cancerjournal_title
Cancerauthors
Bell DA,Flotte TJdoi
10.1002/1097-0142(19820901)50:5<932::aid-cncr28205subject
Has Abstractpub_date
1982-09-01 00:00:00pages
932-8issue
5eissn
0008-543Xissn
1097-0142journal_volume
50pub_type
杂志文章相关文献
CANCER文献大全abstract::This paper discusses the imaging methods available for the detection and diagnosis of colon cancer, concentrating on endoscopy and barium radiology. Effective utilization of these two methods may be facilitated by using flexible sigmoidoscopy to direct further investigation. There is a need for educational efforts to ...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19930615)71:12+<4198::aid-cncr28
更新日期:1993-06-15 00:00:00
abstract:BACKGROUND:Recent advances in the treatment of nasopharyngeal carcinoma (NPC) have transpired into better treatment outcomes for patients with locoregionally advanced NPC, and have broadened the chemotherapeutic options for patients with metastatic disease. METHODS:Data for this review were identified through searches...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.20768
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:The objective of this study was to assess the racial and ethnic disparities in outcomes and their association with process-of-care measures for elderly Medicare recipients with localized prostate cancer. METHODS:The Surveillance, Epidemiology, and End Results-Medicare databases for the period from 1995 to 2...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25812
更新日期:2011-06-01 00:00:00
abstract::A clinicopathologic analysis of 12 cases of a morphologically distinctive non-Hodgkin's malignant lymphoma which appeared to arise from the mantle zones of secondary lymphoid follicles is presented. In lymph node and spleen sections, atypical small lymphoid cells with slightly irregular and indented nuclear contours p...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820401)49:7<1429::aid-cncr2820
更新日期:1982-04-01 00:00:00
abstract:BACKGROUND:Patients with renal masses are at risk for having or developing chronic kidney disease (CKD) stage 3 (glomerular filtration rate [GFR] <60 mL per minute/1.73 m2). In this study, the authors investigated whether the Screening for Occult Renal Disease (SCORED) model could identify patients with renal masses wh...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23850
更新日期:2008-11-15 00:00:00
abstract:BACKGROUND:Caveolin-1 plays a regulatory role in several signaling pathways. Recently caveolin-1 was identified as a metastasis-related gene in prostate carcinoma. However, the clinical impact of caveolin-1 expression in esophageal carcinoma remains unknown. METHODS:One hundred thirty surgical specimens of esophageal ...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:2002-02-15 00:00:00
abstract:BACKGROUND:Based on previous data demonstrating a potentially synergistic interaction between tamoxifen and cisplatin in metastatic melanoma therapy, a Phase II study was performed to assess the activity of tamoxifen, etoposide, mitoxantrone, and cisplatin (TEMP) in patients with metastatic breast carcinoma. METHODS:F...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0142(19961101)78:9<1906::aid-cn
更新日期:1996-11-01 00:00:00
abstract::Blood vessel invasion and axillary lymph node involvement were examined in 175 breast cancer patients. The incidence of blood vessel invasion was 35%. The presence of blood vessel invasion was highly associated with early disease recurrence. The association of poor prognosis with blood vessel invasion was independent ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820901)50:5<962::aid-cncr28205
更新日期:1982-09-01 00:00:00
abstract:BACKGROUND:Interferon-alpha (IFN-alpha) has shown significant activity in the treatment of BCR-ABL-negative myeloproliferative disorders (MPDs), particularly essential thrombocythemia (ET) and polycythemia vera (PV). PEG-IFN-alpha-2b is a pegylated IFN-alpha-2b with a significant advantage over nonpegylated form in tha...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23018
更新日期:2007-11-01 00:00:00
abstract::Meningeal carcinomatosis can appear with a variety of neurologic signs and symptoms. Alterations in respiratory control have not been reported in this syndrome or in neurologic syndromes associated with systemic cancer. The authors report on a case of documented leptomeningeal carcinoma from breast cancer presenting a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810301)47:5<982::aid-cncr28204
更新日期:1981-03-01 00:00:00
abstract::Acute non-lymphocytic leukemia occurred in eight women following long-term treatment with Treosulfan (= dihydroxybusulfan) for ovarian carcinoma. The leukemia developed from 21 to 58 months (median 50 months) after the institution of chemotherapy. At the time when the leukemia appeared seven of the patients were in co...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800101)45:1<19::aid-cncr282045
更新日期:1980-01-01 00:00:00
abstract::Many cancer patients have elevated serum protein and sialic acid (N-acetyl neuraminic acid, NANA) levels. Serial determinations were performed, using serum treated with perchloric acid from 34 patients with widespread metastatic disease. Six of six patients who underwent debulking surgery had a drop in their serum NAN...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810115)47:2<324::aid-cncr28204
更新日期:1981-01-15 00:00:00
abstract::Patients with ER positive primary tumors usually have initial metastases at the more favorable sites. Twelve out of 14 patients with ER positive had first site of metastases in either bone or soft tissue. In contrast, 13 of 17 patients with negative ER developed first metastases in viscera. ER positive patients respon...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19801215)46:12+<2932::aid-cncr28
更新日期:1980-12-15 00:00:00
abstract:BACKGROUND:The objective of this Phase II study was to evaluate the concept of sequential chemotherapy in the treatment of patients with advanced nonsmall cell lung carcinoma (NSCLC) by the administration of carboplatin plus gemcitabine followed by of paclitaxel. METHODS:Patients with Stage IIIB (pleural effusion) or ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(20010701)92:1<146::aid-cncr1302>
更新日期:2001-07-01 00:00:00
abstract::Thirty-six patients were evaluated between 1965 and 1983 for glioma of the optic nerves and/or chiasm. Median follow-up was 10.2 years. Pathologic verification was obtained in 32 patients. Tumor initially confined to the optic nerve recurred in one of five patients after complete resection. The actuarial survival for ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880215)61:4<635::aid-cncr28206
更新日期:1988-02-15 00:00:00
abstract::The development of resistance to purine analogs defines a poor-risk subset of patients with chronic lymphocytic leukemia (CLL). Although in recent years chemoimmunotherapeutic combinations such as fludarabine, cyclophosphamide, and rituximab have induced response rates of 95% in previously untreated patients and incre...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.24329
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:The measurement of estrogen receptors (ER) in breast cancer specimens has traditionally been assessed with a dextran-coated charcoal assay (DCCA). More recently the immunohistochemical staining (IHC) method has gained increasing popularity because of its ability to use fixed tissue, assess needle biopsies, a...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/(SICI)1097-0142(19960815)78:4<764::AID-CNC
更新日期:1996-08-15 00:00:00
abstract:BACKGROUND:To eliminate cranial irradiation (CrRT)-related sequelae and to minimize the adverse impact of traumatic lumbar puncture (TLP) with blasts, the Taiwan Pediatric Oncology Group (TPOG) introduced a modified central nervous system (CNS)-directed regimen characterized by delayed triple intrathecal therapy (TIT) ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/cncr.31758
更新日期:2018-12-01 00:00:00
abstract::This report identifies five general conclusions that emerged from the Second Workshop on Methodology in Behavioral and Psychosocial Cancer Research. These conclusions address diverse topics, including a focus on areas other than methodology; an emphasis on the transfer of technology and knowledge to applied settings; ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910201)67:3+<865::aid-cncr2820
更新日期:1991-02-01 00:00:00
abstract::Androgen deprivation therapy (ADT) is now a well-established standard of care in combination with definitive radiotherapy for patients with unfavorable intermediate-risk to high-risk locally advanced prostate cancer. It is also well established that combination modality treatment with ADT and radiotherapy is superior ...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.28594
更新日期:2014-06-01 00:00:00
abstract::Ovarian, fallopian tube, and peritoneal cancers have a similar clinical presentation and are treated similarly, and current evidence supports staging all 3 cancers in a single system. The primary site (i.e. ovary, fallopian tube, or peritoneum) should be designated where possible. The histologic type should be recorde...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29524
更新日期:2015-10-01 00:00:00
abstract::The effect of cis-diamminedichloroplatinum II (DDP) and ionizing radiation on human bladder transitional cell carcinoma (TCC) was evaluated in nude mouse-grown human tumors following administration of single-agent and combination treatment. Combination of DDP and radiation resulted in accelerated tumor regression and ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19830801)52:3<452::aid-cncr28205
更新日期:1983-08-01 00:00:00
abstract:BACKGROUND:The aim of this study was to examine p16(INK4a) protein expression in ThinPrep (Cytyc Corporation, Marlborough, Mass) cervical specimens by using the CINtec p16(INK4a) Cytology Kit (Dako, Glostrup, Denmark). The ability of this assay to accurately identify underlying high-grade lesions was assessed by using ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22580
更新日期:2007-04-25 00:00:00
abstract::A case-control study was conducted to assess the risk factors associated with the development of a contralateral primary breast cancer among women who had had a first primary breast cancer. Hospital records were reviewed for 292 women with an incident contralateral breast cancer, diagnosed in one of eight hospitals be...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880715)62:2<412::aid-cncr28206
更新日期:1988-07-15 00:00:00
abstract::A case of basosquamous or so-called transitional cloacogenic carcinoma of the sigmoid colon, which arose above the pelvic brim at the peritoneal reflection, is reported. We were not able to find a report of this histologic type of tumor arising this far from the pectinate line of the anus, which is the most common pri...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197709)40:3<1234::aid-cncr282040
更新日期:1977-09-01 00:00:00
abstract::A primary cardiac spindle cell tumor with immunoreactivity for keratin proteins is reported. Cytogenetic analysis of the tumor demonstrated a translocation (X;18), an aberration almost exclusively reported in synovial sarcomas. Postmortem examination revealed amphibole asbestos within the lungs and diaphragmatic pleur...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940101)73:1<74::aid-cncr282073
更新日期:1994-01-01 00:00:00
abstract::Radiation-induced small bowel injury is a limiting factor to postoperative tumoricidal pelvic doses exceeding 4500 to 5000 cGy. Data from a review of the literature showed the inadequacy of medical measures and the bad reproducibility of radiation therapeutic attempts to decrease small intestine damage. Recent studies...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/1097-0142(19911215)68:12<2545::aid-cncr282
更新日期:1991-12-15 00:00:00
abstract::The serum lactase dehydrogenase (LDH) of 56 patients with Ewing's sarcoma was examined to determine the use of LDH as a tumor marker. The initial LDH level was used to determine its ability to predict survival. The follow-up LDH level also was examined, as an indicator of recurrent disease. The initial LDH level was f...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870401)59:7<1245::aid-cncr2820
更新日期:1987-04-01 00:00:00
abstract:BACKGROUND:Several studies have recently reported on the importance of quality of life (QOL) in predicting the survival of patients with lung carcinoma. To confirm these reports, the relationship between survival and QOL, as measured by the European Organization for Research and Treatment of Cancer (EORTC) Quality of L...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/(sici)1097-0142(19990115)85:2<333::aid-cnc
更新日期:1999-01-15 00:00:00
abstract:BACKGROUND:The authors previously demonstrated that never-smokers with stage IIIB/IV nonsmall cell lung cancer (NSCLC) lived 50% longer than former/current smokers. This observation persisted after adjusting for age, performance status, and sex. In this study, the authors hypothesized that smoking-dependent differences...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27637
更新日期:2012-12-01 00:00:00