Glycoproteins and human cancer: II. Correlation between circulating level and disease status.

abstract：BACKGROUND:Targeting the tumor microenvironment and angiogenesis is a novel lymphoma therapeutic strategy. The authors report safety, activity, and angiogenic profiling results with the rituximab and thalidomide plus prednisone, etoposide, procarbazine, and cyclophosphamide (RT-PEPC) regimen in patients with recurrent ...

journal_title：Cancer

authors： Ruan J,Martin P,Coleman M,Furman RR,Cheung K,Faye A,Elstrom R,Lachs M,Hajjar KA,Leonard JP

更新日期：2010-06-01 00:00:00

abstract：:A primary cardiac spindle cell tumor with immunoreactivity for keratin proteins is reported. Cytogenetic analysis of the tumor demonstrated a translocation (X;18), an aberration almost exclusively reported in synovial sarcomas. Postmortem examination revealed amphibole asbestos within the lungs and diaphragmatic pleur...

journal_title：Cancer

authors： Karn CM,Socinski MA,Fletcher JA,Corson JM,Craighead JE

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Hospital services are expectantly reduced over the weekend, which may result in a delay in treatment or in obtainment of medical procedures. The authors investigated quality of care and clinical outcomes of newly diagnosed acute myeloid leukemia (AML) patients who were hospitalized on weekends versus weekday...

journal_title：Cancer

authors： Bejanyan N,Fu AZ,Lazaryan A,Fu R,Kalaycio M,Advani A,Sobecks R,Copelan E,Maciejewski JP,Sekeres MA

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The diagnostic accuracy of technetium-99m methoxyisobutylisonitrile (Tc-MIBI) single photon emission computed tomography (SPECT) and computed tomography (CT) of the head and neck for differentiating recurrent or residual nasopharyngeal carcinomas (NPC) from benign lesions after radiotherapy was compared with...

journal_title：Cancer

authors： Kao CH,Shiau YC,Shen YY,Yen RF

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:In patients with locoregional carcinoma of the esophagus or esophagogastric junction who underwent preoperative chemoradiation, it is unclear whether survival was better predicted by pretherapy clinical stage or by posttherapy pathologic stage. METHODS:The authors studied 235 consecutive patients with preth...

journal_title：Cancer

authors： Chirieac LR,Swisher SG,Ajani JA,Komaki RR,Correa AM,Morris JS,Roth JA,Rashid A,Hamilton SR,Wu TT

更新日期：2005-04-01 00:00:00

abstract：:To collect an unselected total bronchial carcinoma population as a basis for randomized therapy studies during 1971-1976, 537 patients with suspected bronchial carcinoma were investigated. Of these, 109 were found to have an adenocarcinoma in the lung. Of the 109, 10 had been initially diagnosed as not having adenocar...

journal_title：Cancer

authors： Nõu E

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:In the current study, the authors attempted to describe the incidence, most common sites, and mortality of second primary malignancies among survivors of common cancers. METHODS:The authors identified patients aged ≥18 years who were diagnosed with a primary malignancy from the 10 most common cancer sites (...

journal_title：Cancer

authors： Donin N,Filson C,Drakaki A,Tan HJ,Castillo A,Kwan L,Litwin M,Chamie K

更新日期：2016-10-01 00:00:00

abstract：:An unusual case of myeloproliferative disorder in which mature and immature myeloid cells were found to contain unusual cytoplasmic inclusions is reported. By light microscopy, these inclusions could be observed with Wright's stain. By electron microscopy they appeared to consist of a pale, finely granular material wi...

journal_title：Cancer

authors： Coppola A,O'Connor J

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Modern cancer treatments can cure or prolong patients' lives. However, the associated physical and psychosocial problems can detrimentally affect patients' compliance with treatment and, ultimately, their outcomes. Therefore, oncologists need to recognize the problems experienced by their patients and, when ...

journal_title：Cancer

authors： Newell S,Sanson-Fisher RW,Girgis A,Bonaventura A

更新日期：1998-10-15 00:00:00

abstract：:Numerous morphologic features have been described in bone marrow and peripheral blood in myelodysplastic syndrome (MDS). We draw attention to a high incidence of a subtle morphologic feature, internuclear bridging (INB), not previously recognized as a morphologic feature in MDS. The occurrence of INB in MDS suggests a...

journal_title：Cancer

authors： Head DR,Kopecky K,Bennett JM,Grenier K,Morrison FS,Miller KB,Grever MR

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Although delay to diagnosis after a breast screening abnormality causes anxiety, its effect on prognosis is unknown. METHODS:Using pooled data from five Canadian organized breast cancer screening programs, the authors used unconditional logistic regression to evaluate the effect of delay to diagnosis on pro...

journal_title：Cancer

authors： Olivotto IA,Gomi A,Bancej C,Brisson J,Tonita J,Kan L,Mah Z,Harrison M,Shumak R

更新日期：2002-04-15 00:00:00

abstract：:This report describes a case of null cell congenital acute lymphoblastic leukemia associated with a (4;11) translocation. This chromosome abnormality is associated with acute lymphoblastic leukemia and probably more specifically with congenital acute lymphoblastic leukemia. A review of the literature is presented. ...

journal_title：Cancer

authors： Esseltine DW,Vekemans M,Seemayer T,Reece E,Gordon J,Whitehead VM

更新日期：1982-08-01 00:00:00

abstract：:Elevated circulating CEA levels occur in patients with benign gastrointestinal and hepatic disorders. These are usually less than 10 ng/ml. Of clinical importance is the influence of liver disease on the interpretation of CEA. At least 50% of patients with severe benign hepatic disease have elevated CEA levels, most o...

journal_title：Cancer

authors： Loewenstein MS,Zamcheck N

更新日期：1978-09-01 00:00:00

abstract：:Therapy for acute lymphocytic leukemia (ALL) has been less successful in adults than in children. Many centers treat all adult leukemia with the same regimen. We have used vincristine and prednisone for initial therapy in 14 adults with ALL since 1971 and have followed a treatment regimen developed for childhood ALL f...

journal_title：Cancer

authors： Scavino HF,George JN,Sears DA

更新日期：1976-08-01 00:00:00

abstract：:Review of 61 surgically resected small hepatocellular carcinomas (HCC) less than or equal to 3 cm in diameter yielded a simple gross classification system of five types based on tumor shape, which is highly correlated with microscopic and clinical features, including prognosis. Type 1 (single nodular type) tumors (n =...

journal_title：Cancer

authors： Kanai T,Hirohashi S,Upton MP,Noguchi M,Kishi K,Makuuchi M,Yamasaki S,Hasegawa H,Takayasu K,Moriyama N

更新日期：1987-08-15 00:00:00

abstract：:Chemotherapy for tumors of the central nervous system has a limited efficacy presumably because of restricted blood-brain barrier permeability. The advantage of regional intra-arterial administration of anticancer drugs is an increased uptake during the first passage of the drugs through tumor capillaries. Twenty pati...

journal_title：Cancer

authors： Madajewicz S,Chowhan N,Iliya A,Roque C,Beaton R,Davis R,Fertman S,Meek A,Alvarez O,Pampati M

更新日期：1991-06-01 00:00:00

abstract：:Disease that is known to have extended beyond the prostatic capsule is unlikely to be cured by radical surgical excision, although the primary tumor may be controlled by external irradiation. The development of progressive (metastatic) disease is common and may be retarded by hormonal therapy. The timing of such treat...

journal_title：Cancer

authors： Smith PH

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:The authors previously identified sperm protein 17 (Sp17) as being expressed in patients with multiple myeloma. The restricted expression of Sp17 in normal tissue makes it an ideal target for tumor vaccine. In the current study, the authors extended their research to include ovarian carcinoma. METHODS:A pai...

journal_title：Cancer

authors： Chiriva-Internati M,Wang Z,Salati E,Timmins P,Lim SH

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Between 1980-1990, 126 patients were treated with radiation therapy (RT) and hyperthermia using 915-MHz external microwave applicators. All but 11 patients had failed to respond to previous therapy. METHODS:The mean tumor volume was 73 +/- 13 cm3, and the mean radiation dose delivered was 45 +/- 1 Gy. Hyper...

journal_title：Cancer

authors： Engin K,Leeper DB,Tupchong L,Waterman FM,Mansfield CM

更新日期：1993-07-01 00:00:00

abstract：:The authors present a retrospective review of 90 cases of Stage III endometrial carcinoma seen over a 10-year period at the Princess Margaret Hospital, Toronto. Overall 5-year survival was 45.5% and disease-free survival was 36.0%. Prognostic factors identified within Stage III were tumor grade, geographic distributio...

journal_title：Cancer

authors： Mackillop WJ,Pringle JF

更新日期：1985-11-15 00:00:00

abstract：:The clinical course of a 33-year-old man with generalized lymphadenopathy bearing all physical, laboratory and histologic characteristics of "angio-immunoblastic lymphadenopathy with dysproteinemia" (AILD) is described. Therapy was without significant benefit and the patient died 22 months after initial diagnosis. At ...

journal_title：Cancer

authors： Yataganas X,Papadimitriou C,Pangalis G,Loukopoulos D,Fessas P,Papacharalampous N

更新日期：1977-05-01 00:00:00

abstract：:Certain features of nodular sclerosing Hodgkin's disease predispose toward achievement of excellent radiotherapeutic results using clinical staging rather than currently advocated surgical staging including laparatomy. These include a distinct pattern of contiguous lymphatic involvement and the infrequent disseminatio...

journal_title：Cancer

authors： Johnson RE,Zimbler H,Berard CW,Herdt J,Brereton HD

更新日期：1977-04-01 00:00:00

abstract：:A high percentage of children with Wilms' tumor are cured with multimodal treatment. A small percentage of these children will develop second tumors, perhaps related to a genetic predisposition to neoplasia or possibly secondary to the treatment utilized for Wilms' tumor. Malignant mesothelioma has been associated wit...

journal_title：Cancer

authors： Antman KH,Ruxer RL Jr,Aisner J,Vawter G

更新日期：1984-07-15 00:00:00

abstract：:This survey of the incidence of melanoma in New South Wales, Australia, from 1970 to 1976 revealed a doubling of incidence in the seven year period. The most marked rise occurred in 1972. A marked preponderance of leg melanoma in women and trunk melanoma in men was noted. The incidence of melanoma in men continues to ...

journal_title：Cancer

authors： McCarthy WH,Black AL,Milton GW

更新日期：1980-07-15 00:00:00

abstract：:A patient is described in whom the first recurrence of a cloacogenic carcinoma of the rectum was an intrahepatic metastasis associated with an hepatic abscess caused by the anaerobic bacterium Peptococcus prevotii. Three previously reported cases of infection associated with hepatic tumor nodules have been found in wh...

journal_title：Cancer

authors： Trump DL,Fahnestock R,Cloutier CT,Dickman MD

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Several investigators have reported the ability to establish xenografts in nude mice from children with neuroblastomas, but a correlation of prognosis with this establishment and the growth patterns of the neuroblastomas has not been reported. METHODS:Tumor specimens from 58 children with neuroblastomas wer...

journal_title：Cancer

authors： George BA,Yanik G,Wells RJ,Martin LW,Soukup S,Ballard ET,Gartside PS,Lampkin BC

更新日期：1993-12-01 00:00:00

abstract：:Malignant fibrous histiocytoma of soft tissues (MFH), a mesenchymal tumor of varied morphologic patterns and cell types, sometimes contains bone and cartilage. Such bony and cartilaginous elements in a pleomorphic MFH may pose a difficult diagnostic challenge. An MFH with bone and cartilage can be distinguished from e...

journal_title：Cancer

authors： Bhagavan BS,Dorfman HD

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:PD-L1 (programmed death ligand 1, B7-H1) is a cell surface glycoprotein that can impair T-cell function. PD-L1 is aberrantly expressed by multiple human malignancies and has been shown to carry a highly unfavorable prognosis in patients with kidney cancer. The role of PD-L1 was evaluated as a mechanism for l...

journal_title：Cancer

authors： Inman BA,Sebo TJ,Frigola X,Dong H,Bergstralh EJ,Frank I,Fradet Y,Lacombe L,Kwon ED

更新日期：2007-04-15 00:00:00

abstract：BACKGROUND:Although state Medicaid programs cover cancer screening, Medicaid beneficiaries are less likely to be screened for cancer and are more likely to present with tumors of an advanced stage than are those with other insurance. The current study was performed to determine whether state Medicaid eligibility and re...

journal_title：Cancer

authors： Halpern MT,Romaire MA,Haber SG,Tangka FK,Sabatino SA,Howard DH

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Oral leukoplakia is a premalignant lesion, but the genetic changes in the foci of early cancerization in leukoplakia have not been studied. METHODS:Loss of heterozygosity (LOH) was successively investigated in 13 cases in the leukoplakia and foci of early cancerization in the same leukoplakia. The authors m...

journal_title：Cancer

authors： Jiang WW,Fujii H,Shirai T,Mega H,Takagi M

更新日期：2001-11-01 00:00:00