Pathogenetic implications of internuclear bridging in myelodysplastic syndrome. An Eastern Cooperative Oncology Group/Southwest Oncology Group Cooperative Study.

abstract：BACKGROUND:An increased incidence of cancer, especially hematopoietic in origin, has long been suspected but never established in patients with Gaucher disease. METHODS:To determine whether patients with Gaucher disease have an increased risk of cancer, the authors conducted a retrospective cohort study, comparing the...

journal_title：Cancer

authors： Shiran A,Brenner B,Laor A,Tatarsky I

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Despite recent advances in diagnosis and treatment, gastric carcinoma remains a major cause of death in the world. METHODS:The clinicopathologic profile of 10,000 consecutive patients who underwent primary gastrectomy during 1962-1989 were reviewed and prognostic factors influencing survival in those with g...

journal_title：Cancer

authors： Nakamura K,Ueyama T,Yao T,Xuan ZX,Ambe K,Adachi Y,Yakeishi Y,Matsukuma A,Enjoji M

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Despite the characteristic histopathologic appearance of alveolar soft-part sarcoma (ASPS), its histogenesis remains unclear, and cytogenetic analysis of ASPS is limited to eight cases so far because of the extreme rarity of this disease. METHODS:The authors document a cytogenetic study of a primary case of...

journal_title：Cancer

authors： Joyama S,Ueda T,Shimizu K,Kudawara I,Mano M,Funai H,Takemura K,Yoshikawa H

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:The objective of this study was to characterize chronic disease, health-related quality of life (HRQOL), emotional distress, and social attainment among long-term survivors of neuroblastoma. METHODS:Chronic health conditions among 136 ≥10-year neuroblastoma survivors (median age, 31.9 years; range, 20.2-54....

journal_title：Cancer

authors： Wilson CL,Brinkman TM,Cook C,Huang S,Hyun G,Green DM,Furman WL,Bhakta N,Ehrhardt MJ,Krasin MJ,Robison LL,Ness KK,Hudson MM

更新日期：2020-03-15 00:00:00

abstract：BACKGROUND:The Tecumseh Community Health Study (TCHS), initiated in 1959 at the University of Michigan School of Public Health, has provided a resource for long term prospective studies of the incidence of cancer in the setting of a midwestern rural farming community. METHODS:A survey of total and site specific cancer...

journal_title：Cancer

authors： Waterhouse D,Carman WJ,Schottenfeld D,Gridley G,McLean S

更新日期：1996-02-15 00:00:00

abstract：BACKGROUND:The influence of various clinicopathologic features on survival of patients with papillary thyroid carcinoma has been examined. In particular, histologic grade, which was obtained by a combined assessment of nuclear atypia, tumor necrosis, and vascular invasion (VAN score) was studied. According to this, his...

journal_title：Cancer

authors： Akslen LA

更新日期：1993-11-01 00:00:00

abstract：:This study is based on 38 patients, each of whom had a malignant lymphoma in which the gonad was the site of the main tumor mass at the time of diagnosis. Histiocytic lymphoma was the predominant type in the 27 male patients; in the 11 female patients, poorly differentiated lymphocytic lymphoma was the most frequent t...

journal_title：Cancer

authors： Paladugu RR,Bearman RM,Rappaport H

更新日期：1980-02-01 00:00:00

abstract：:A 42-year-old woman developed lower extremity weakness and sensory loss 1 year after external and intracavitary radiotherapy for Stage IB carcinoma of cervix. She has been followed for 5 years posttreatment, and the neurologic abnormalities have persisted, but no evidence of recurrent carcinoma has been found. We beli...

journal_title：Cancer

authors： Stryker JA,Sommerville K,Perez R,Velkley DE

更新日期：1990-10-01 00:00:00

abstract：:The DNA stemline ploidy was assessed in paraffin-embedded, formalin-fixed primary tumor tissue from 68 patients with nonseminomatous germ cell cancer (NSCGT) clinical Stage I (CS I). Forty-three patients had a single aneuploid (greater than 1C) DNA stemline, whereas 24 patients had multiple aneuploid stemlines. In one...

journal_title：Cancer

authors： Fosså SD,Nesland JM,Waehre H,Amellem O,Pettersen EO

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:The presence of urinary excretion products of human chorionic gonadotropin (hCG) has been proposed as a tumor marker. To ascertain the clinical value in gynecologic cancers, the authors studied 612 nonpregnant women. METHODS:Three different assays in four clinical groups were compared: no disease, benign di...

journal_title：Cancer

authors： Neven P,Iles RK,Lee CL,Hudson CN,Shepherd JH,Chard T

更新日期：1993-06-15 00:00:00

abstract：BACKGROUND:Molecular genetic studies of ovarian cancer have been limited by the inaccessible location of the ovary, the advanced stage of tumors available for analysis, and the lack of a well-defined precursor lesion. However, genetic alterations important in ovarian tumorigenesis have been identified recently. METHOD...

journal_title：Cancer

authors： Gallion HH,Pieretti M,DePriest PD,van Nagell JR Jr

更新日期：1995-11-15 00:00:00

abstract：BACKGROUND:PD-L1 (programmed death ligand 1, B7-H1) is a cell surface glycoprotein that can impair T-cell function. PD-L1 is aberrantly expressed by multiple human malignancies and has been shown to carry a highly unfavorable prognosis in patients with kidney cancer. The role of PD-L1 was evaluated as a mechanism for l...

journal_title：Cancer

authors： Inman BA,Sebo TJ,Frigola X,Dong H,Bergstralh EJ,Frank I,Fradet Y,Lacombe L,Kwon ED

更新日期：2007-04-15 00:00:00

abstract：:A case is reported of a patient with pancreatic carcinoma who developed pancreatic ascites after intraoperative fine-needle aspiration cytology (FNAC) biopsy. This complication of FNAC has not previously been reported to the authors' knowledge. The literature is reviewed, and FNAC is shown to be the safest method of p...

journal_title：Cancer

authors： Rosenbaum DA,Frost DB

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Many trials submitted to scientific meetings are not reported in peer-reviewed journals. Results may vary substantially and the lack of final publication constitutes a form of reporting bias. The authors sought to determine the presentation and publication rates of Phase I trials submitted to a major oncolog...

journal_title：Cancer

authors： Camacho LH,Bacik J,Cheung A,Spriggs DR

更新日期：2005-10-01 00:00:00

abstract：:The authors discovered some errors regarding reference group labels in Table 2. The corrected table is attached. The authors regret these errors. ...

journal_title：Cancer

authors：

更新日期：2015-03-01 00:00:00

abstract：:Jaundice and hepatomegaly developed in a boy with Fanconi anemia after he had undergone treatment with oxymetholone for nine years. A liver scan showed patchy uptake consistent with the presence of space-occupying lesions. After oxymetholone treatment was stopped, the jaundice resolved, the liver size decreased, and t...

journal_title：Cancer

authors： Obeid DA,Hill FG,Harnden D,Mann JR,Wood BS

更新日期：1980-09-15 00:00:00

abstract：BACKGROUND:The current study was conducted to evaluate severe mucocutaneous toxicity during treatment with hydroxyurea (HU) in a large cohort of patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPN). METHODS:Among 993 consecutive patients newly diagnosed with MPN at 4 centers in Rome betwee...

journal_title：Cancer

authors： Latagliata R,Spadea A,Cedrone M,Di Giandomenico J,De Muro M,Villivà N,Breccia M,Anaclerico B,Porrini R,Spirito F,Rago A,Avvisati G,Alimena G,Montanaro M,Andriani A,Gruppo Laziale SMPC Ph1 neg.

更新日期：2012-01-15 00:00:00

abstract：:A case of meningeal melanocytoma of the left Meckel's cave associated with ipsilateral Ota's nevus in a 43-year-old woman, was studied by light and electron microscopy. The cells of the tumor were characterized by the presence of dendritic cytoplasmic processes, melanosomes and premelanosomes; hence, they were deemed ...

journal_title：Cancer

authors： Botticelli AR,Villani M,Angiari P,Peserico L

更新日期：1983-06-15 00:00:00

abstract：METHODS:Between 1983 and 1989, 42 patients with Stage II, III, and IV, node-negative, squamous cell head and neck cancer were treated with concurrent 5-fluorouracil, cisplatin, and radiation therapy. Two courses of chemotherapy with 30 Gy of concurrent radiation therapy were to be followed in all patients by definitive...

journal_title：Cancer

authors： Adelstein DJ,Sharan VM,Damm C,Earle AS,Shah AC,Haria CD,Trey JE,Carter SG,Hines JD

更新日期：1992-12-01 00:00:00

abstract：:The case of a 49-year-old man with the diagnosis of angioimmunoblastic lymphadenopathy is reported. The patient survived a stormy clinical course. The corticosteroids improved dramatically the clinical picture although the patient developed a staphylococcal septicemia. Before treatment immunological studies were done ...

journal_title：Cancer

authors： Kosmidis PA,Axelrod AR,Palacas C,Stahl M

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Hepatocyte growth factor receptor (c-met), autocrine motility factor receptor (AMFR), and urokinase-type plasminogen activator receptor (uPAR) are known to play important roles in tumor cell migration, invasion, and metastasis. The authors studied the relation between the expression patterns of these genes a...

journal_title：Cancer

authors： Taniguchi K,Yonemura Y,Nojima N,Hirono Y,Fushida S,Fujimura T,Miwa K,Endo Y,Yamamoto H,Watanabe H

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Lysosomal proteases are implicated in cancer progression and metastasis. In the current study, using subtraction cloning for genes that are differentially expressed in metastasis, the authors isolated a clone encoding ceroid lipofuscinosis, neuronal 2 (CLN2), which is a lysosomal serine protease defective in...

journal_title：Cancer

authors： Tsukamoto T,Iida J,Dobashi Y,Furukawa T,Konishi F

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Patients with aggressive non-Hodgkin lymphoma (NHL) require intensive and extensive therapy, which seems impracticable in elderly patients due to hematologic and extrahematologic toxicity. Consequent dose reduction and therapy attenuation can reduce treatment-related toxicity but also decreases therapeutic e...

journal_title：Cancer

authors： Rigacci L,Carpaneto A,Alterini R,Carrai V,Bernardi F,Bellesi G,Longo G,Bosi A,Rossi Ferrini P

更新日期：2003-01-01 00:00:00

abstract：:One hundred ninety-one patients with gastrointestinal leiomyosarcomas were analyzed to determine the prevalence in patterns of failure and the factors predicting those at higher risk of relapse at specific sites. Of 100 assessable patients who died of disease, 89% were found to have peritoneal tumor, 78% had liver met...

journal_title：Cancer

authors： Ng EH,Pollock RE,Romsdahl MM

更新日期：1992-03-15 00:00:00

abstract：:109 cases of breast cancer were treated by tumorectomy and radiotherapy or radiotherapy alone. Almost 30% with small tumors (T1, T2) were considered inoperable for medical reasons and 70% refused mastectomy. Over the past five years the number of patients refusing mastectomy has definitely increased. 59 cases of surgi...

journal_title：Cancer

authors： Alpert S,Ghossein NA,Stacey P,Migliorelli FA,Efron G,Krishnaswamy V

更新日期：1978-10-01 00:00:00

abstract：:"Bowen's disease" is a clinical and histologic diagnosis describing the lesions (single or multiple) of cutaneous in situ squamous cell carcinoma. The case of a 54-year-old man with 60 such intra-epidermal carcinomas, and a history of arsenic ingestion, is presented. The patient was sensitized to dinitrochlorobenzene ...

journal_title：Cancer

authors： Raaf JH,Krown SE,Pinsky CM,Cunningham-Rundles W,Safai B,Oettgen HF

更新日期：1976-04-01 00:00:00

abstract：:Although the conference could not provide a definitive etiologic explanation for the observed increase in incidence of human brain tumors, particularly among the elderly, nevertheless, this interdisciplinary gathering of prominent scientists and clinicians proved invaluable in identifying new avenues of research. Clea...

journal_title：Cancer

authors： Brem S,Rozental JM,Moskal JR

更新日期：1995-08-15 00:00:00

abstract：BACKGROUND:Because carcinomas of unknown primary origin are highly malignant tumors with a bad prognosis (median survival, 6-12 months) and no current optimal therapy, the authors designed a prospective dose-dense chemotherapy regimen with the objective of improving the results observed in patients who receive conventi...

journal_title：Cancer

authors： Culine S,Fabbro M,Ychou M,Romieu G,Cupissol D,Pinguet F

更新日期：2002-02-01 00:00:00

abstract：:Eighteen patients with isolated vaginal recurrence of their previously treated endometrial carcinoma were treated with radiation therapy at North Carolina Baptist Hospital, Winston-Salem between 1971 and 1982. Most patients received external beam irradiation which were followed by boost treatments that were delivered ...

journal_title：Cancer

authors： Greven K,Olds W

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:It is questionable whether enrollment on clinical trials offers any survival advantage at the population level over standard-of-care treatment. The objectives of this study were to describe the impact of trial enrollment on event-free survival and overall survival in pediatric acute myeloid leukemia (AML) us...

journal_title：Cancer

authors： Truong TH,Pole JD,Barber R,Dix D,Kulkarni KP,Martineau E,Randall A,Stammers D,Strahlendorf C,Strother D,Sung L

更新日期：2018-10-15 00:00:00