Concurrent radiation therapy, 5-fluorouracil, and cisplatin for stage II, III, and IV, node-negative, squamous cell head and neck cancer. Results and surgical implications.

abstract：BACKGROUND:Pediatric renal cell carcinoma (RCC) is clinically distinct from adult RCC. Characterization of the unique biological and clinical features of pediatric RCC are required. METHODS:A retrospective review and biological analysis of all RCC cases presenting to Cincinnati Children's Hospital Medical Center (CCHM...

journal_title：Cancer

authors： Geller JI,Argani P,Adeniran A,Hampton E,De Marzo A,Hicks J,Collins MH

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:This study was performed to evaluate the effect of positive margins, Gleason grade, and capsular penetration on progression after radical prostatectomy. METHODS:The authors followed 507 men with totally embedded retropubic prostatectomy specimens performed for clinical Stages A and B prostate cancer for a m...

journal_title：Cancer

authors： Epstein JI,Pizov G,Walsh PC

更新日期：1993-06-01 00:00:00

abstract：:Human cases autopsied at the Department of Pathology, University of Tokyo, were studied to investigate the chronologic changes in the relationship between cigarette smoking and lung cancer occurrence. The results obtained were as follows: (1) it was confirmed that the incidence of lung cancer was significantly higher ...

journal_title：Cancer

authors： Mori W,Sakai R

更新日期：1984-09-15 00:00:00

abstract：:Patients who are diagnosed with osteosarcoma (OS) today receive the same therapy that patients have received over the last 4 decades. Extensive efforts to identify more effective or less toxic regimens have proved disappointing. As we enter a postgenomic era in which we now recognize OS not as a cancer of mutations bu...

journal_title：Cancer

authors： Roberts RD,Lizardo MM,Reed DR,Hingorani P,Glover J,Allen-Rhoades W,Fan T,Khanna C,Sweet-Cordero EA,Cash T,Bishop MW,Hegde M,Sertil AR,Koelsche C,Mirabello L,Malkin D,Sorensen PH,Meltzer PS,Janeway KA,Gorlick R,Cro

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:Reports utilizing data from the Commission on Cancer's National Cancer Data Base (NCDB) have previously contained evaluations of time trends for stage of disease at diagnosis, treatment, and survival for multiple tumor sites. Data collected from 1989, 1990, 1994, and 1995 for carcinoma of the gallbladder are...

journal_title：Cancer

authors： Donohue JH,Stewart AK,Menck HR

更新日期：1998-12-15 00:00:00

abstract：METHODS:The diagnostic performance of transrectal ultrasound (TRUS) gland volume and prostate specific antigen (PSA) results were evaluated in 204 men consecutively scheduled to undergo transurethral prostatic resection (TUR). RESULTS:Nonpalpable prostate cancer was detected by TRUS alone in 18% (29 of 161) and by TUR...

journal_title：Cancer

authors： Lee F,Littrup PJ,Loft-Christensen L,Kelly BS Jr,McHugh TA,Siders DB,Mitchell AE,Newby JE

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:The authors conducted a comprehensive review of the efficacy of 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography (FDG-PET) in the detection of primary tumors in patients with disseminated carcinoma of unknown primary site. METHODS:Ten studies (involving a total of 221 patients) tat were publish...

journal_title：Cancer

authors： Sève P,Billotey C,Broussolle C,Dumontet C,Mackey JR

更新日期：2007-01-15 00:00:00

abstract：BACKGROUND:Deletion or loss of heterozygosity (LOH) at the polymorphic loci on the short arm of chromosome 3 has been reported in a large number of renal cell, small cell lung, non-small cell lung, and cervical carcinomas, suggesting the presence of one or more putative tumor suppressor genes at chromosome 3p. Similar ...

journal_title：Cancer

authors： el-Naggar AK,Lee MS,Wang G,Luna MA,Goepfert H,Batsakis JG

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Childhood cancer is a highly curable disease when timely diagnosis and appropriate therapy are provided. A negative impact of the coronavirus disease 2019 (COVID-19) pandemic on access to care for children with cancer is likely but has not been evaluated. METHODS:A 34-item survey focusing on barriers to ped...

journal_title：Cancer

authors： Saab R,Obeid A,Gachi F,Boudiaf H,Sargsyan L,Al-Saad K,Javakhadze T,Mehrvar A,Abbas SS,Abed Al-Agele YS,Al-Haddad S,Al Ani MH,Al-Sweedan S,Al Kofide A,Jastaniah W,Khalifa N,Bechara E,Baassiri M,Noun P,El-Houdzi J,K

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Insulin receptor (IR), a member of the receptor tyrosine kinase family, is expressed in normal thyroid cells and affects thyroid cell proliferation and differentiation. METHODS:The authors measured IR content in benign and malignant thyroid tumors by three independent methods: a specific radioimmunoassay, 1...

journal_title：Cancer

authors： Frittitta L,Sciacca L,Catalfamo R,Ippolito A,Gangemi P,Pezzino V,Filetti S,Vigneri R

更新日期：1999-01-15 00:00:00

abstract：:Sequential corrected creatinine clearance (CCC) evaluations were obtained in 30 patients treated with intra-arterial and/or intravenous cis-diamminedichloroplatinum-II (CDP). The dose was 150 mg/M2 administered with mannitol diuresis at 2 to 3 weekly intervals. Four hundred fifty-three courses were administered (range...

journal_title：Cancer

authors： Jaffe N,Keifer R 3rd,Robertson R,Cangir A,Wang A

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Multiple cell-signaling ligands and receptors-including vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF), endothelial growth factor (EGF), v-akt murine thymoma viral oncogene homolog (AKT), platelet-derived growth factor (PDGF), mitogen-activated protein kinase (MAPK), and 70-kilod...

journal_title：Cancer

authors： Abdeen A,Chou AJ,Healey JH,Khanna C,Osborne TS,Hewitt SM,Kim M,Wang D,Moody K,Gorlick R

更新日期：2009-11-15 00:00:00

abstract：BACKGROUND:The authors previously identified sperm protein 17 (Sp17) as being expressed in patients with multiple myeloma. The restricted expression of Sp17 in normal tissue makes it an ideal target for tumor vaccine. In the current study, the authors extended their research to include ovarian carcinoma. METHODS:A pai...

journal_title：Cancer

authors： Chiriva-Internati M,Wang Z,Salati E,Timmins P,Lim SH

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to characterize insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF-1R) expression in patients with nonsmall cell lung cancer (NSCLC). METHODS:A total of 459 patients who underwent curative resection of NSCLC were studied (median follow-up duration, 4.01 years)...

journal_title：Cancer

authors： Kim JS,Kim ES,Liu D,Lee JJ,Solis L,Behrens C,Lippman SM,Hong WK,Wistuba II,Lee HY

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Theoretical considerations have raised the suspicion that transurethral resection of the prostate (TURP) may increase the risk of developing prostate cancer in clinically benign prostate glands. Previous studies have not shown an increased risk among men who had undergone TURP for benign prostatic hyperplasi...

journal_title：Cancer

authors： Hammarsten J,Andersson S,Holmén A,Högstedt B,Peeker R

更新日期：1994-10-15 00:00:00

abstract：BACKGROUND:In view of the many studies of early stage colorectal carcinoma from Japan, it is essential to know whether the criteria for the histologic diagnosis of colorectal carcinoma are similar in Japan and Western countries. METHODS:Eight expert pathologists from Japan (4), North America (2), and Europe (2) indivi...

journal_title：Cancer

authors： Schlemper RJ,Itabashi M,Kato Y,Lewin KJ,Riddell RH,Shimoda T,Sipponen P,Stolte M,Watanabe H

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:4'-0-tetrahydropyranyladriamycin (Pirarubicin, Meiji Seika (USA) Inc., New York, NY) may be less toxic than doxorubicin. METHODS:A Phase II trial of Pirarubicin was done in 26 patients who had not previously had chemotherapy and who had measurable and incurable head and neck carcinoma. All patients received...

journal_title：Cancer

authors： Sridhar KS,Hussein AM,Benedetto P,Ardalan B,Savaraj N,Richman SP

更新日期：1992-09-15 00:00:00

abstract：BACKGROUND:Sequential systematic biopsies after radiotherapy (RT) for prostate carcinoma were evaluated with respect to radiation effect, tumor differentiation, and prostate specific antigen (PSA) staining, and these histopathologic parameters were correlated with local outcome. METHODS:Since 1990, transrectal ultraso...

journal_title：Cancer

authors： Crook JM,Bahadur YA,Robertson SJ,Perry GA,Esche BA

更新日期：1997-01-01 00:00:00

abstract：:Granular cell tumor of the stomach is rare and may occur in association with similar tumors in the skin. Two such tumors were found in association with cutaneous granular cell tumors in two black females. Infiltrating carcinoma of the stomach was suspected at surgery in one case. All of the lesions were typical granul...

journal_title：Cancer

authors： Seo IS,Azzarelli B,Warner TF,Goheen MP,Senteney GE

更新日期：1984-05-15 00:00:00

abstract：:A tumor colony assay (TCA) was evaluated for its ability to predict anticancer drug responses in an N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT)-induced murine bladder tumor (MBT) model. Ten anticancer drugs were evaluated in vivo and in vitro using four MBT cell lines (40 drug responses). Using the optimum c...

journal_title：Cancer

authors： Niell HB,Soloway MS,Wood CA,McCallum LW,Webster K

更新日期：1983-08-15 00:00:00

abstract：:DNA-aneuploid primary melanomas are said to show a greater propensity to metastasize than those without an aneuploid profile. A higher aneuploid rate has also been reported in metastatic melanomas than in primary lesions. The ploidy profile was determined of 26 primary melanomas and their first subsequent secondaries ...

journal_title：Cancer

authors： Rode J,Williams RA,Charlton IG,Dhillon AP,Moss E

更新日期：1991-05-01 00:00:00

abstract：:Disease that is known to have extended beyond the prostatic capsule is unlikely to be cured by radical surgical excision, although the primary tumor may be controlled by external irradiation. The development of progressive (metastatic) disease is common and may be retarded by hormonal therapy. The timing of such treat...

journal_title：Cancer

authors： Smith PH

更新日期：1993-02-01 00:00:00

abstract：:Histologic examination of bone-marrow from the posterior iliac crest was routinely done as a pretreatment staging procedure in 203 consecutive patients with small-cell anaplastic carcinoma of the lung. Subtyping of the patients according to the WHO classification included 27.8% with "fusiform" cell type (WHO II,1), 28...

journal_title：Cancer

authors： Hirsch F,Hansen HH,Dombernowsky P,Hainau B

更新日期：1977-06-01 00:00:00

abstract：:The unique case of a 60-year-old patient with a non-Hodgkin's B-cell lymphoma of the lymphoplasmacytic type and three associated monoclonal proteins, is described. The patient also exhibited various autoimmune phenomena that were consistent with the diagnoses of Sjögren's syndrome and autoimmune thyroiditis. The evolu...

journal_title：Cancer

authors： Berg AR,Weisenburger DD,Linder J,Armitage JO

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:The antiviral, proapoptotic, antiproliferative gene 2'-5' oligoadenylate synthetase (2-5OAS1) converts adenosine triphosphate into a series of 2'-5' oligoadenylates (2-5A). In turn, 2-5A activates latent ribonuclease (RNaseL), a candidate hereditary prostate cancer gene. OAS1 polymorphism (reference single n...

journal_title：Cancer

authors： Mandal S,Abebe F,Chaudhary J

更新日期：2011-12-15 00:00:00

abstract：:A solitary tumor which by light microscopy was calssified as a neurofibroma was found by electron microscopic study to be composed of parallel, elongate cells with collagen rich intervening matrix. The cells showed thin, polar cytoplasmic processes which extended long distances, frequent junctional complexes between c...

journal_title：Cancer

authors： Lazarus SS,Trombetta LD

更新日期：1978-05-01 00:00:00

abstract：:Patients with ER positive primary tumors usually have initial metastases at the more favorable sites. Twelve out of 14 patients with ER positive had first site of metastases in either bone or soft tissue. In contrast, 13 of 17 patients with negative ER developed first metastases in viscera. ER positive patients respon...

journal_title：Cancer

authors： Singhakowinta A,Saunders DE,Brooks SC,Samal B,Vaitkevicius VK

更新日期：1980-12-15 00:00:00

abstract：:Flow cytometry (FC) analysis including DNA index (ploidy status) and cell kinetics (%S and %S + G2/M) was done on frozen tissue of the primary lesions of 101 women with node negative (N-) breast cancer who were studied prospectively. Currently, 19% (19/101) of the patients have recurred. No significant relations have ...

journal_title：Cancer

authors： Muss HB,Kute TE,Case LD,Smith LR,Booher C,Long R,Kammire L,Gregory B,Brockschmidt JK

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Radioimmunotherapy with radiolabeled monoclonal antibodies to CD20 produces a high response rate in patients with recurring non-Hodgkin lymphoma (NHL), but the durability of those remissions is not well defined. METHODS:Data on patients with recurring NHL treated with yttrium Y 90 ibritumomab tiuxetan in 4 ...

journal_title：Cancer

authors： Witzig TE,Molina A,Gordon LI,Emmanouilides C,Schilder RJ,Flinn IW,Darif M,Macklis R,Vo K,Wiseman GA

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Nonsmall cell lung carcinomas (NSCLCs) are associated with very dismal prognoses, and adjuvant chemotherapy, including irinotecan, taxanes, platin, and vinca alkaloid derivatives, offer patients only slight clinical benefits. Part of the chemoresistance of NSCLC results from the expression in NSCLC cells of ...

journal_title：Cancer

authors： Mathieu A,Remmelink M,D'Haene N,Penant S,Gaussin JF,Van Ginckel R,Darro F,Kiss R,Salmon I

更新日期：2004-10-15 00:00:00