Abstract:
:A solitary tumor which by light microscopy was calssified as a neurofibroma was found by electron microscopic study to be composed of parallel, elongate cells with collagen rich intervening matrix. The cells showed thin, polar cytoplasmic processes which extended long distances, frequent junctional complexes between cell processes, numerous surface vesicles, and either no or fragmented and variable basement membrane. Perineurial cells from small peripheral nerves of skin were demonstrated to have similar morphologic characteristics as the tumor cells. The present study, together with previous ultrastructural findings, indicate that benign peripheral nerve sheath tumors should be placed in at least three categories: Schwannoma, neurofibroma and perineurioma.
journal_name
Cancerjournal_title
Cancerauthors
Lazarus SS,Trombetta LDdoi
10.1002/1097-0142(197805)41:5<1823::aid-cncr282041subject
Has Abstractpub_date
1978-05-01 00:00:00pages
1823-9issue
5eissn
0008-543Xissn
1097-0142journal_volume
41pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:This study was conducted to evaluate the long-term outcomes in patients with stage IE and IIE mucosa-associated lymphoid tissue (MALT) lymphomas treated with involved field radiotherapy (RT). METHODS:Between 1989 and 2004, 192 patients with stage I and II MALT lymphomas were treated. The report focuses on 1...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25226
更新日期:2010-08-15 00:00:00
abstract::Two patients fulfilled the clinical and hematologic criteria for B-cell acute lymphoblastic leukemia: the malignant cells had L3 morphology, bore B-cell markers, and carried the specific t(8;14) translocation. The leukemic cells of one patient were tetrasomic for 1q, and those of the other patient showed several separ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840701)54:1<48::aid-cncr282054
更新日期:1984-07-01 00:00:00
abstract::Hereditary adenomatosis of the colon and rectum (HACR) is associated with a wide variety of extracolonic manifestations. Two cases of neoplasia involving the adrenal gland are reported, one adenoma and one carcinoma. The literature relating these lesions to HACR and other syndromes of malignant and nonmalignant growth...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850501)55:9<2001::aid-cncr2820
更新日期:1985-05-01 00:00:00
abstract:BACKGROUND:We sought to determine the impact of radical nephrectomy case volume, hospital size, and geographic region on immediate surgical outcomes for patients undergoing radical nephrectomy in academic centers across the country. METHODS:The University HealthSystem Consortium (UHC) Clinical Data Base was queried fo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24292
更新日期:2009-06-01 00:00:00
abstract::A series of case-control studies was conducted to investigate cancer risks among farmers. These studies were based on Missouri Cancer Registry data for 15,000 white male patients, including 1720 subjects classified as farmers, registered between 1984 and 1988. For each cancer site, all other cancer registrations forme...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19891201)64:11<2381::aid-cncr282
更新日期:1989-12-01 00:00:00
abstract:BACKGROUND:Insular thyroid carcinoma was described originally as a tumor with aggressive behavior. However, whether a predominant insular component is an independent factor for poor prognosis is unclear. METHODS:The authors compared the clinical behavior of tumors in three groups of patients with thyroid carcinoma--13...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10947
更新日期:2002-11-15 00:00:00
abstract::Oral fluorouracil was administered weekly to 12 consecutive patients with unresectable hepatoma. Six patients showed an objective response with a significant increase in survival duration compared to nonresponders and to untreated patients. The clinical features of these cases are discussed, along with details of ther...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197705)39:5<1930::aid-cncr282039
更新日期:1977-05-01 00:00:00
abstract::Extensive bone marrow necrosis is an unusual histologic finding most commonly identified after autopsy. We describe a patient with poorly differentiated lymphocytic lymphoma who manifested pancytopenia and marrow necrosis. Bone marrow scanning with 99mTc-sulfur-minicolloid provided a noninvasive means to assess the ex...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19801115)46:10<2168::aid-cncr282
更新日期:1980-11-15 00:00:00
abstract:BACKGROUND:The objective of this analysis was to evaluate the role of autologous stem cell transplantation (ASCT) in prolonging disease free survival (DFS) and overall survival (OS) in patients with chronic myeloid leukemia (CML) who received autografts of Philadelphia chromosome (Ph) positive or Ph negative cell harve...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10931
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:Consumers increasingly consult the Internet for breast cancer information. Concerned about accuracy, multiple organizations developed quality criteria for online content. However, the effectiveness of these tools is unknown. The authors determined whether existing quality criteria can identify inaccurate bre...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23308
更新日期:2008-03-15 00:00:00
abstract:BACKGROUND:Although thin cutaneous melanomas generally have a favorable prognosis, in some cases they may undergo progression. The current study was undertaken to identify variables that may predict a more aggressive clinical outcome in these patients. In addition to classic clinicopathologic features, the authors test...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19990301)85:5<1067::aid-cn
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:Effective multidisciplinary rehabilitation programs supporting the return to work have become increasingly relevant for cancer survivors. In Germany, inpatient work-related medical rehabilitation programs consider treatment modules of work-related diagnostics, work-related functional capacity training, psych...
journal_title:Cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/cncr.32131
更新日期:2019-08-01 00:00:00
abstract::The authors performed immunohistochemical and cytogenetic studies in a 73-year old man with malignant angioendotheliomatosis. The patient was referred for evaluation of fever of unknown origin, hepatic failure, and neurologic deterioration. Examination of a muscle biopsy revealed numerous, noncohesive atypical mononuc...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900801)66:3<474::aid-cncr28206
更新日期:1990-08-01 00:00:00
abstract::A panel of Japanese and American pathologists reviewed existing histologic material used to study breast cancer risk among the A-bomb survivors in Hiroshima and Nagasaki, a population in which incidence studies have found a strong relationship between breast cancer risk and radiation dose. The primary charge to the pa...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840901)54:5<849::aid-cncr28205
更新日期:1984-09-01 00:00:00
abstract:BACKGROUND:The objective of this Phase II study was to evaluate the concept of sequential chemotherapy in the treatment of patients with advanced nonsmall cell lung carcinoma (NSCLC) by the administration of carboplatin plus gemcitabine followed by of paclitaxel. METHODS:Patients with Stage IIIB (pleural effusion) or ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(20010701)92:1<146::aid-cncr1302>
更新日期:2001-07-01 00:00:00
abstract::The presence of hepatitis B virus (HBV) has been evaluated in liver specimens from 11 children with primary liver tumors and negative results of serologic testing for HBV markers. HBV-DNA sequences were detected by the polymerase chain reaction procedure, using different sets of oligonucleotide primers from highly con...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920601)69:11<2731::aid-cncr282
更新日期:1992-06-01 00:00:00
abstract:BACKGROUND:The current study was conducted to evaluate the Patient-Reported Outcomes Measurement Information System Depression Short Form (PROMIS-D-SF) as a screening measure for young adult cancer survivors (YACS) compared with a structured diagnostic interview. METHODS:A total of 249 YACS (aged 18-40 years) complete...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.32689
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Neuropilins (NRPs) are characterized as coreceptors of vascular endothelial growth factor (VEGF). In the current study, the authors assessed the expression of NRPs, VEGF, and vascular endothelial growth factor receptors (VEGFRs), as well as VEGF-induced cell proliferation, in pancreatic carcinoma cell lines ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20634
更新日期:2004-11-15 00:00:00
abstract::There are three principal disturbances in bone remodelling that occur in neoplasia affecting the skeleton. The first is an increase in bone turnover that in solid tumors may be confined to sites of metastases or be a generalized phenomenon, most likely related to the secretion of parathyroid hormone-related protein. I...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-0142(19971015)80:8+<1538::aid-c
更新日期:1997-10-15 00:00:00
abstract:BACKGROUND:Vascular endothelial growth factor (VEGF) signaling is a target for antiangiogenic cancer therapy. The authors have previously observed that up to 40% of vessels in colorectal carcinoma (CRC) tumors are negative for VEGF receptor 2 (VEGFR2) expression. Differential activity of transforming growth factor beta...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26247
更新日期:2011-12-15 00:00:00
abstract:BACKGROUND:The diagnostic accuracy of technetium-99m methoxyisobutylisonitrile (Tc-MIBI) single photon emission computed tomography (SPECT) and computed tomography (CT) of the head and neck for differentiating recurrent or residual nasopharyngeal carcinomas (NPC) from benign lesions after radiotherapy was compared with...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/cncr.10400
更新日期:2002-04-01 00:00:00
abstract::Surgery is the most effective treatment for thyroid cancer; however, in some subsets of patients, the role of radiotherapy (RT) is important. The main indication for external-beam RT is incomplete surgery. When neoplastic tissue is left behind at operation, RT must be considered, but only if an experienced surgeon fee...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850501)55:9+<2062::aid-cncr282
更新日期:1985-05-01 00:00:00
abstract:BACKGROUND:The goal of the current study was to investigate the prognostic impact of proliferative activity, together with the other classic clinicopathologic prognostic factors (tumor size, tumor grade, receptor status, ploidy, and lymph node status), in breast carcinoma by counting mitoses and evaluating S phase frac...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11916
更新日期:2004-02-01 00:00:00
abstract:BACKGROUND:In addition to possessing many physiologic functions, human growth hormone-1 (GH1) has been shown in recent in vitro and in vivo experiments to induce malignant disease, including breast carcinoma. The authors investigated the association of breast carcinoma with genetic polymorphisms in the GH1 gene in the ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20375
更新日期:2004-07-15 00:00:00
abstract::Two human Burkitt's lymphoma cell lines (HBL-4 and HBL-5) were established individually from two patients with small noncleaved cell lymphoma (Burkitt's type). The HBL-4 cell line is Epstein-Barr virus (EBV)-negative, and the HBL-5 cell line is EBV-positive. Cytogenetically, both cell lines had the same chromosomal tr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920201)69:3<763::aid-cncr28206
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:Patients with bulky laryngopharyngeal masses and a relative or absolute contraindication to general anesthesia present diagnostic difficulties. In the current study, the authors assessed the utility of transcutaneous ultrasound-guided Tru-Cut biopsy (USGTCB) under local anesthesia in such individuals. METHO...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22679
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Survivors of childhood leukemia/lymphoma are at increased risk for reduced bone mineral density (BMD). The authors sought to determine the frequency of reduced BMD detected by off-therapy surveillance, factors associated with reduced BMD, and the association of reduced BMD with fractures. METHODS:This cross...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.32512
更新日期:2020-01-01 00:00:00
abstract::From the standpoint of chemotherapy, the first progress in the treatment of Hodgkin's disease was the identification of the activity of nitrogen mustard in the 1940's. The initial antitumor effect of the drug created a great excitement. However, when all patients later relapsed, there was subsequent dejection and skep...
journal_title:Cancer
pub_type: 临床试验,历史文章,杂志文章,评审
doi:10.1002/1097-0142(197808)42:2+<979::aid-cncr282042
更新日期:1978-08-01 00:00:00
abstract:BACKGROUND:Patients with metachronous multiple colorectal carcinomas have been reported to have a higher frequency of a family history of colorectal carcinoma, associated colorectal adenomas, and extracolonic malignancies. These clinicopathologic factors also are considered to be related to the development of metachron...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:Radiofrequency thermal ablation (RFA) is a new minimally invasive treatment for localized cancer. Minimally invasive surgical options require less resources, time, recovery, and cost, and often offer reduced morbidity and mortality, compared with more invasive methods. To be useful, image-guided, minimally i...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.10234
更新日期:2002-01-15 00:00:00