Abstract:
BACKGROUND:Consumers increasingly consult the Internet for breast cancer information. Concerned about accuracy, multiple organizations developed quality criteria for online content. However, the effectiveness of these tools is unknown. The authors determined whether existing quality criteria can identify inaccurate breast cancer information online. METHODS:The authors identified 343 unique webpages by using 15 breast cancer-related queries on 5 popular web search-engines. Each page was assessed for 15 quality criteria and 3 website characteristics, link type (sponsored or not), search engine used to find the page, and domain extension. Two clinician-reviewers independently assessed accuracy and topics covered. The authors then determined whether quality criteria, website characteristics, and topics were associated with the presence of inaccurate statements. RESULTS:The authors found 41 inaccurate statements on 18 webpages (5.2%). No quality criteria or website characteristic, singly or in combination, reliably identified inaccurate information. The total number of quality criteria met by a website accounted for a small fraction of the variability in the presence of inaccuracies (point biserial r=-0.128; df=341; P=.018; r2=0.016). However, webpages containing information on complementary and alternative medicine (CAM) were significantly more likely to contain inaccuracies compared with pages without CAM information (odds ratio [OR], 15.6; P<.001). CONCLUSIONS:Most breast cancer information that consumers are likely to encounter online is accurate. However, commonly cited quality criteria do not identify inaccurate information. Webpages that contain information about CAM are relatively likely to contain inaccurate statements. Consumers searching for health information online should still consult a clinician before taking action.
journal_name
Cancerjournal_title
Cancerauthors
Bernstam EV,Walji MF,Sagaram S,Sagaram D,Johnson CW,Meric-Bernstam Fdoi
10.1002/cncr.23308subject
Has Abstractpub_date
2008-03-15 00:00:00pages
1206-13issue
6eissn
0008-543Xissn
1097-0142journal_volume
112pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:In cholangiocarcinoma, no established method of analysis of lymph node metastasis has been reported with respect to the surgical outcome. METHODS:The authors retrospectively examined the pattern of lymph node metastasis and the surgical outcome with reference to the International Union Against Cancer (UICC)...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1998-11-01 00:00:00
abstract::Breast reconstruction is not a new idea. Techniques have been developing since the late 1800s. The state of the art is such that the knowledge of its availability and success has significant effect on the willingness of women to seek earlier diagnosis and treatment. However, reconstruction is not for everyone. This pa...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19910901)68:5+<1167::aid-cncr282
更新日期:1991-09-01 00:00:00
abstract::Four courses of ifosfamide with mesna given by intravenous infusions were combined with bolus doxorubicin in a phase II trial to treat patients with breast cancer. Ifosfamide can deplete intracellular glutathione levels and because doxorubicin resistance may be associated with elevated levels of intracellular glutathi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900601)65:11<2421::aid-cncr282
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND:Hypoxia inducible factor-1 (HIF-1) plays a critical role in angiogenesis during vascular development. The authors tested the hypothesis that HIF-1 expression correlates with progression and angiogenesis in brain tumors. METHODS:The authors investigated the expression of the HIF-1alpha and HIF-1beta subunits...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract::Four patients with benign giant cell tumor and one patient with probable benign giant cell tumor associated with Paget's disease of bone are reported. The familial and geographic clustering of these cases is unique in that three patients were related and all patients traced ancestral roots to the same area of southern...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197908)44:2<742::aid-cncr2820440
更新日期:1979-08-01 00:00:00
abstract::The survival of cervical carcinoma patients with paraaortic/high common iliac nodal metastases was evaluated by retrospective chart review during a 13-year interval. Thirty-three patients with cervical carcinoma and surgically documented nodal metastases received primary, extended-field radiation therapy. Overall 2-ye...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19900715)66:2<251::aid-cncr28206
更新日期:1990-07-15 00:00:00
abstract:BACKGROUND:p16 is strongly overexpressed in dysplastic cervical cells because of the transforming activity of the E7 oncogene of all high-risk human papillomavirus (HR-HPV) types and may be easily revealed by immunochemistry: p16 may, therefore, be considered a surrogate marker for the activated oncogene expression of ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21713
更新日期:2006-04-25 00:00:00
abstract::Over the last 20 to 30 years, a recognition and general acceptance of the entity of malignant fibrous histiocytoma and monophasic synovial sarcoma has occurred. The introduction of these diagnostic categories among the generic group of spindle cell sarcomas now requires a reevaluation of the more traditional and histo...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19890815)64:4<925::aid-cncr28206
更新日期:1989-08-15 00:00:00
abstract:BACKGROUND:The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous cell population is necessar...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/cncr.11331
更新日期:2003-08-25 00:00:00
abstract:BACKGROUND:The current study was conducted to evaluate the Patient-Reported Outcomes Measurement Information System Depression Short Form (PROMIS-D-SF) as a screening measure for young adult cancer survivors (YACS) compared with a structured diagnostic interview. METHODS:A total of 249 YACS (aged 18-40 years) complete...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.32689
更新日期:2020-04-01 00:00:00
abstract::The clinical course of melanoma of the skin diagnosed during pregnancy was compared with a control population of women with melanoma that occurred during the childbearing years, as recorded by the Connecticut Tumor Registry. The survival at three and five years for the 12 patients whose melanoma developed during pregn...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810715)48:2<407::aid-cncr28204
更新日期:1981-07-15 00:00:00
abstract::Quantitative counts of ferruginous bodies were performed on digests of lungs from 100 control and 30 lung cancer patients. It was found that the lung cancer group had significantly higher levels, although only 1 patient was known to be occupationally exposed to asbestos. It is suggested that even extremely low levels ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197504)35:4<1236::aid-cncr282035
更新日期:1975-04-01 00:00:00
abstract:BACKGROUND:Despite recent advances in diagnosis and treatment, gastric carcinoma remains a major cause of death in the world. METHODS:The clinicopathologic profile of 10,000 consecutive patients who underwent primary gastrectomy during 1962-1989 were reviewed and prognostic factors influencing survival in those with g...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920901)70:5<1030::aid-cncr2820
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND:Clinical trials established the value of breast-conserving treatment (BCT) including the macroscopic removal of the tumor followed by local radiation therapy (RT) for Stage I and II invasive carcinomas. The occurrence of local tumor recurrence is related to the extent and multifocality of the tumor. Various ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20010215)91:4<647::aid-cncr1053>
更新日期:2001-02-15 00:00:00
abstract::A patient is described with Gardner's syndrome manifested initially by an extra-abdominal desmoid which was resected. The case was complicated by metastatic adenocarcinoma of the colon and recurrence of several large painful desmoid lesions. In view of the predilection of desmoids to occur in women in their childbeari...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19831215)52:12<2201::aid-cncr282
更新日期:1983-12-15 00:00:00
abstract::We reviewed the records of 104 patients with Stage T1NO or Stage T2NO epidermoid carcinoma of the supraglottic larynx treated between 1965 and 1979. In 79 patients, surgery was the only type of initial treatment. These 79 patients are the subjects of this report. Forty-eight (61%) of these patients were treated by tot...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890115)63:2<345::aid-cncr28206
更新日期:1989-01-15 00:00:00
abstract:BACKGROUND:The pretherapy prediction of occult lymph node involvement and the avoidance of otherwise futile and potentially morbid definitive local therapy is paramount in men with newly diagnosed prostate carcinoma. To identify patients with prostate carcinoma who likely have lymph node involvement and would benefit f...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:1999-04-01 00:00:00
abstract::Hodgkin's disease (HD) was diagnosed in 24 patients who were either seropositive for human immunodeficiency virus (HIV) (21) or members of a high-risk group (three), but had not developed acquired immune deficiency syndrome (AIDS). Clinical presentation of the disease was characterized by constitutional symptoms in al...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910315)67:6<1614::aid-cncr2820
更新日期:1991-03-15 00:00:00
abstract:BACKGROUND:There is limited published evidence regarding the efficacy of total skin electron beam radiation for patients with the diffuse erythrodermic form of mycosis fungoides. METHODS:Forty-five patients with erythrodermic mycosis fungoides were managed at McMaster University in Hamilton, Ontario, Canada (n=34), an...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0142(19990501)85:9<1985::aid-cn
更新日期:1999-05-01 00:00:00
abstract::This study examined public attitudes toward pain associated with cancer and its treatment. A variety of issues were assessed, including the extent to which pain is associated with cancer, fear of pain as a factor in the decision to delay seeking treatment, and concerns about the use of narcotic analgesics for pain con...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19851101)56:9<2337::aid-cncr2820
更新日期:1985-11-01 00:00:00
abstract::A case of congenital acute lymphoblastic leukemia (ALL) displayed an X;6 translocation. This is the third reported case of ALL with an X;6 translocation. In addition, two of the three ALL cases occurred during infancy, at ages 2 months and newborn, and both translocations involved the band q15-16 region of chromosome ...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19920201)69:3<799::aid-cncr28206
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:There is considerable evidence that one of the strongest risk factors for breast carcinoma can be assessed from the mammographic appearance of the breast. However, the magnitude of the risk factor and the reliability of the prediction depend on the method of classification. Subjective classification requires...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19970701)80:1<66::aid-cncr
更新日期:1997-07-01 00:00:00
abstract:BACKGROUND:Fine-needle aspiration biopsy (FNA) has been successful in diagnosing epithelial lesions of the breast. Its role in the evaluation of spindle cell and mesenchymal lesions of the breast, which include a variety of benign and malignant conditions, is less clear. This article discusses the cytologic features an...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19991225)87:6<359::aid-cnc
更新日期:1999-12-25 00:00:00
abstract:BACKGROUND:The intraoperative evaluation of axillary sentinel lymph nodes (SLNs) allows the surgeon to complete axillary dissection in 1 setting at the time of the primary breast surgery. However, to the authors' knowledge, there is no consensus regarding the optimal method for intraoperative evaluation of SLNs in brea...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24182
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Despite the widespread use of oxaliplatin-based regimens for colorectal and other gastrointestinal cancers, there is surprisingly little information regarding their empiric use for the treatment of carcinoma of unknown primary site (CUP). In the current study, the combination of oxaliplatin and capecitabine ...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.25029
更新日期:2010-05-15 00:00:00
abstract::Computed tomography (CT) has emerged from the 1980s to play a dominant role in the pretreatment staging of renal and adrenal carcinomas. For detection, definition (staging), and determination of resectability or recurrence, CT with intravenous contrast enhancement, and more recently, magnetic resonance imaging (MRI) w...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19910215)67:4+<1199::aid-cncr282
更新日期:1991-02-15 00:00:00
abstract::Parathyroid adenomas are subdivided into chief cell and oxyphil cell variants. However, the parathyroid carcinomas described thus far have been only of the chief cell type. Two cases of oxyphil cell carcinoma of the parathyroid gland are reported, with light and electron microscopic study. The patients presented appar...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850401)55:7<1482::aid-cncr2820
更新日期:1985-04-01 00:00:00
abstract::The results of surgical treatment alone for 142 cases of carcinoma of the rectum and rectosigmoid from the Massachusetts General Hospital were reviewed. The incidence of local failure as any component of failure was found to be strongly dependent on the pathologic stage, and for Dukes' A was 8.0% (3/39); Dukes' B, 31%...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19831001)52:7<1317::aid-cncr2820
更新日期:1983-10-01 00:00:00
abstract::Malignant salivary gland neoplasms in children are rare. Such tumors usually occur in the parotid gland of older children. Sixteen cases of major salivary gland malignancy are reviewed, 14 occurring in the parotid gland and two in the submandibular gland. Adenoid cystic carcinoma was the most common malignancy encount...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850415)55:8<1730::aid-cncr2820
更新日期:1985-04-15 00:00:00
abstract::Four cases of childhood hepatic angiosarcoma (HAS), representing the malignant form of infantile hemangioendothelioma, are described. The morphologic appearance of childhood HAS differs from the adult form in the following features: the associated presence of benign infantile hemangioendothelioma; the presence of dyso...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810115)47:2<382::aid-cncr28204
更新日期:1981-01-15 00:00:00