Parathyroid carcinoma of the oxyphil cell type. A report of two cases, light and electron microscopic study.

abstract：:From January, 1973, to June, 1976, 226 patients with palpable ovarian masses were evaluated preoperatively by lymphography. Histology showed 166 cases of malignant epithelial tumors, 26 benign tumors, and 34 malignant special tumors (not included in this report). Furthermore, the group of patients included 99 recurren...

journal_title：Cancer

authors： Musumeci R,Banfi A,Bolis G,Candiani GB,De Palo G,Di Re F,Lucina L,Lattuada A,Mangioni C,Mattioli G,Natale N

更新日期：1977-10-01 00:00:00

abstract：:In a former series of 60 resected Stage II nonseminomatous germinal testis tumors the authors succeeded in demonstrating that adjuvant cisplatin, vinblastine, and bleomycin (PVB) was able to significantly improve survival (100% in 11 treated versus 28.5% in 7 historical controls, P less than 0.01) only in patients wit...

journal_title：Cancer

authors： Pizzocaro G,Zanoni F,Milani A,Piva L,Salvioni R,Pasi M,Pilotti S,Monfardini S

更新日期：1984-03-15 00:00:00

abstract：:Leukemic cells from 13 patients with therapy-related acute nonlymphocytic leukemia (ANLL) were studied by electron microscopy. All of the patients had radiotherapy, and/or alkylating agent chemotherapy for other neoplastic disease 25 to 182 months prior to the diagnosis of ANLL. All cases manifested ultrastructural ev...

journal_title：Cancer

authors： McKenna RW,Parkin JL,Foucar K,Brunning RD

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Outcomes for patients with relapsed/refractory acute myeloid leukemia (R/R AML) remain poor. Novel therapies specifically targeting AML are of high interest. Brentuximab vedotin (BV) is an antibody-drug conjugate that is specific for human CD30. In this phase 1 dose escalation study, the authors evaluated th...

journal_title：Cancer

authors： Narayan R,Blonquist TM,Emadi A,Hasserjian RP,Burke M,Lescinskas C,Neuberg DS,Brunner AM,Hobbs G,Hock H,McAfee SL,Chen YB,Attar E,Graubert TA,Bertoli C,Moran JA,Bergeron MK,Foster JE,Ramos AY,Som TT,Vartanian MK,

更新日期：2020-03-15 00:00:00

abstract：BACKGROUND:Interleukin-2 (IL-2) has immunomodulatory effects, including stimulating the activity of cytotoxic T cells and natural killer cells, and inducing the generation of lymphokine-activated killer cells. The authors investigated whether IL-2 may improve the duration of complete remission (CR) and survival in acut...

journal_title：Cancer

authors： Cortes JE,Kantarjian HM,O'Brien S,Giles F,Keating MJ,Freireich EJ,Estey EH

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Heat shock protein 60 (Hsp60) is a chaperonin involved in tumorigenesis, but its participation in tumor development and progression is not well understood and its value as a tumor biomarker has not been fully elucidated. In the current study, the authors presented evidence supporting the theory that Hsp60 ha...

journal_title：Cancer

authors： Campanella C,Rappa F,Sciumè C,Marino Gammazza A,Barone R,Bucchieri F,David S,Curcurù G,Caruso Bavisotto C,Pitruzzella A,Geraci G,Modica G,Farina F,Zummo G,Fais S,Conway de Macario E,Macario AJ,Cappello F

更新日期：2015-09-15 00:00:00

abstract：:Serum complements, C3, C4, and C3 proactivator (C3PA), were evaluated prospectively for their diagnostic power in detecting hepatocellular carcinoma (HCC) in patients with liver cirrhosis (LC). Sixty-three LC patients, including 36 LC with HCC patients, were recruited for this study during the period from March to Nov...

journal_title：Cancer

authors： Chang WY,Chuang WL

更新日期：1988-07-15 00:00:00

abstract：BACKGROUND:Metastases to the breast from extramammary primary tumors are uncommon. Malignant melanoma is one of the most common neoplasms to secondarily involve the mammary parenchyma. METHODS:Seven cases of malignant melanoma metastatic to the breast diagnosed by fine-needle aspiration biopsy are presented. RESULTS:...

journal_title：Cancer

authors： Cangiarella J,Symmans WF,Cohen JM,Goldenberg A,Shapiro RL,Waisman J

更新日期：1998-06-25 00:00:00

abstract：BACKGROUND:Intracranial primitive neuroectodermal tumors (PNETs) occur in the supratentorial and infratentorial regions of the brain. Although histologically similar, the natural history of the tumor at each site differs. The study goal was to determine whether there was evidence of a genetic difference between suprate...

journal_title：Cancer

authors： Russo C,Pellarin M,Tingby O,Bollen AW,Lamborn KR,Mohapatra G,Collins VP,Feuerstein BG

更新日期：1999-07-15 00:00:00

abstract：:Forty-milligram strips of malignant breast tissue were divided longitudinally into 20-mg microsamples. Soluble protein concentration was determined for one-half, and histologic evaluation for viable carcinoma content was made on its sister half. The correlation coefficient for 88 such comparisons was 0.330. This sugge...

journal_title：Cancer

authors： van Netten JP,Algard FT,Coy P,Carlyle SJ,Brigden ML,Thornton KR,To MP

更新日期：1982-06-01 00:00:00

abstract：:This is a statistical analysis of the use of mammography in the symptomatic patient. Eighty-eight percent of women older than 50 years who had a palpable cancer of the breast had a positive mammogram; only 57% of women younger than 51 years of age had a positive mammogram. When the cancer presented as nipple discharge...

journal_title：Cancer

authors： Edeiken S

更新日期：1989-04-01 00:00:00

abstract：:Solitary plasmacytoma of bone (SPB) and extramedullary plasmacytoma (EMPC) are unusual solitary tumors of plasma cell origin. The clinical differences between these tumors and multiple myeloma are the subject of continued study. This review examines the radiotherapy experience at M. D. Anderson Hospital. Between 1948 ...

journal_title：Cancer

authors： Corwin J,Lindberg RD

更新日期：1979-03-01 00:00:00

abstract：:Forty-five patients with advanced non-small cell lung cancer (NSCLC), with progressive inoperable tumors were treated. Twenty-three patients were of "limited" stage. Six patients had received previous thoracic radiotherapy. Patients with central nervous system (CNS) metastases, Karnofsky scores of less than 30 or more...

journal_title：Cancer

authors： Thatcher N,Smith DB,Lind MJ,Anderson H,Barclay J,Chopra MP,Fitzgerald MD

更新日期：1988-01-01 00:00:00

abstract：:Over the last decade, new cytotoxic treatments and targeted therapies have altered treatment paradigms for patients with metastatic non-small cell lung cancer (NSCLC). We sought to analyze the impact of histology and biomarker selection criteria on outcomes of clinical trials in metastatic NSCLC reported over the last...

journal_title：Cancer

authors： Gentzler RD,Yentz SE,Johnson ML,Rademaker AW,Patel JD

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:We investigated p16(INK4A) expression in branchial cleft cysts and its utility in distinguishing branchial cleft cysts from metastatic head and neck squamous cell carcinomas (SCCs) in fine-needle aspiration biopsies (FNABs). METHODS:A study set comprising 41 resections (15 SCC and 26 branchial cleft cysts) ...

journal_title：Cancer

authors： Pai RK,Erickson J,Pourmand N,Kong CS

更新日期：2009-04-25 00:00:00

abstract：:In estrogen target tissues and hormone-dependent tumors, the steroid enters the cells and binds to a cytoplasmic protein called the estrogen receptor (ER). The steroid-receptor complex then migrates to the nuclei, where it initiates the biochemicial events characteristic of estrogen stimulation. Since ER is absent in ...

journal_title：Cancer

authors： McGuire WL

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:Telomerase is commonly recognized as an effective anticancer target. The human telomerase reverse transcriptase (hTERT), the rate-limiting component of telomerase, is expressed in most malignant tumors, but it is not found in most normal somatic cells. Here, we report a real-time and noninvasive method to mo...

journal_title：Cancer

authors： Yu ST,Li C,Lü MH,Liang GP,Li N,Tang XD,Wu YY,Shi CM,Chen L,Li CZ,Cao YL,Fang DC,Yang SM

更新日期：2012-04-01 00:00:00

abstract：:A prospective study of patients receiving cis-diaminedichloroplatin II (DDP) was carried out to determine if risk factors could be identified related to the patient's living habits or past medical history that would predict in which patients DDP neuropathy might develop. Sixty-nine patients receiving six different com...

journal_title：Cancer

authors： Mollman JE,Glover DJ,Hogan WM,Furman RE

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:The recommended phase 2 dose (RP2D) of anticancer agents is determined traditionally by dose-limiting toxicities. Nontoxicity or biological endpoints such as pharmacokinetics, pharmacodynamics, and efficacy can also be used to identify RP2D, which may be relevant to molecularly targeted agents (MTAs). METHO...

journal_title：Cancer

authors： Hansen AR,Cook N,Amir E,Siu LL,Abdul Razak AR

更新日期：2017-04-15 00:00:00

abstract：:Acid phosphatase activity biochemically in the primary tumor of 20 patients with prostatic carcinoma, was studied in an attempt to understand the basis for a correlation or lack of correlation between serum and/or bone marrow acid phosphatase levels and the presence and/or clinical behavior of prostatic carcinoma. The...

journal_title：Cancer

authors： Copland GT,Whitehurst GB,Pretlow TP,Boohaker EA,Bartolucci AA,Pretlow TG 2nd

更新日期：1983-07-01 00:00:00

abstract：:A 78-year-old Japanese man with chronic liver disease developed hypervascular liver tumors accompanied by marked elevation of alphafetoprotein value (the highest level; 26200 ng/ml) and pathologic fracture of the femur. After an operation for the fracture followed by gastrointestinal bleeding and repeated transfusions...

journal_title：Cancer

authors： Sato Y,Fujiwara K,Nakagawa S,Kanishima S,Ohta Y,Oka Y,Hayashi S,Oka H

更新日期：1985-08-01 00:00:00

abstract：:The role of 99mTc-pertechnetate thyroid imaging in the preoperative assessment of patients with single palpable thyroid nodules was evaluated. The frequency of cancer in hypofunctional nodules was similar to that found in previous studies with 131I. The 99mTc-pertechnetate image allowed a reliable separation of pathol...

journal_title：Cancer

authors： Alderson PO,Sumner HW,Siegel BA

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Multimodality treatment has dramatically improved the outcome of patients with Ewing sarcoma. However, there appears to be little information concerning treatment-related complications in patients who are long-term survivors. METHODS:Forty-one patients with Ewing sarcoma who were treated between 1960-1980 a...

journal_title：Cancer

authors： Fuchs B,Valenzuela RG,Inwards C,Sim FH,Rock MG

更新日期：2003-12-15 00:00:00

abstract：:Amputation is often a component in the treatment of bone tumors such as osteogenic sarcoma, which is most prevalent in the adolescent age group. Adaptation to cancer and loss of a limb requires a significant multidimensional effort. To examine the role of social support systems, 27 adolescents who had undergone amputa...

journal_title：Cancer

authors： Tebbi CK,Stern M,Boyle M,Mettlin CJ,Mindell ER

更新日期：1985-08-15 00:00:00

abstract：BACKGROUND:The degree of response and the duration of survival of patients treated with mitogen-activated protein kinase (MAPK) inhibitors are highly variable. Whether baseline clinicopathologic factors can predict the clinical course with treatment is largely unknown. METHODS:For 142 consecutive immunotherapy- and MA...

journal_title：Cancer

authors： Menzies AM,Wilmott JS,Drummond M,Lo S,Lyle M,Chan MM,Thompson JF,Guminski A,Carlino MS,Scolyer RA,Kefford RF,Long GV

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:This qualitative study investigated the medical decision-making preferences of adolescent oncology patients and the parental and clinician behaviors that adolescents report to be supportive of their preferred level of decision-making involvement. METHODS:Interviews were conducted with 40 adolescents between...

journal_title：Cancer

authors： Weaver MS,Baker JN,Gattuso JS,Gibson DV,Sykes AD,Hinds PS

更新日期：2015-12-15 00:00:00

abstract：:This report is based on 903 patients with resections for gastric carcinoma between October 1957, and July 1969, entered in controlled trials of adjuvant therapy with Thio-TEPA and FUDR. Neither Thio-TEPA nor FUDR, as administered, prolonged survival. The extent of disease at the time of curative surgery is related to ...

journal_title：Cancer

authors： Serlin O,Keehn RJ,Higgins GA Jr,Harrower HW,Mendeloff GL

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Melanoma is the most lethal form of skin cancer, with an estimated 68,130 new cases and 8700 deaths in the United States in 2010. The increasing incidence and high death rate associated with metastatic disease support the need to focus on prevention. The authors used data from the Women's Health Initiative (...

journal_title：Cancer

authors： Jagtap D,Rosenberg CA,Martin LW,Pettinger M,Khandekar J,Lane D,Ockene I,Simon MS

更新日期：2012-10-15 00:00:00

abstract：BACKGROUND:Hyalinizing clear cell carcinoma (HCCC) is an uncommon malignant salivary gland tumor that was characterized only recently as a distinct entity. Because of its histologic similarity to several other primary and metastatic tumors and its purported favorable clinical outcome after local resection, it is import...

journal_title：Cancer

authors： Solar AA,Schmidt BL,Jordan RC

更新日期：2009-01-01 00:00:00

abstract：:Disease that is known to have extended beyond the prostatic capsule is unlikely to be cured by radical surgical excision, although the primary tumor may be controlled by external irradiation. The development of progressive (metastatic) disease is common and may be retarded by hormonal therapy. The timing of such treat...

journal_title：Cancer

authors： Smith PH

更新日期：1993-02-01 00:00:00