Acid phosphatase in prostatic tissue homogenates from patients with benign prostatic hyperplasia and prostatic carcinoma.

Abstract:

:Acid phosphatase activity biochemically in the primary tumor of 20 patients with prostatic carcinoma, was studied in an attempt to understand the basis for a correlation or lack of correlation between serum and/or bone marrow acid phosphatase levels and the presence and/or clinical behavior of prostatic carcinoma. The enzyme activity was similarly measured in 19 patients with benign prostatic hyperplasia as controls. On the average, enzyme activities were lower (P less than 0.002) in the tissues from patients with carcinoma. There was no correlation of enzyme activity in tumor with the age of the patient, stage of disease, degree of differentiation of the tumor, or serum acid phosphatase activity.

journal_name

Cancer

journal_title

Cancer

authors

Copland GT,Whitehurst GB,Pretlow TP,Boohaker EA,Bartolucci AA,Pretlow TG 2nd

doi

10.1002/1097-0142(19830701)52:1<155::aid-cncr28205

subject

Has Abstract

pub_date

1983-07-01 00:00:00

pages

155-60

issue

1

eissn

0008-543X

issn

1097-0142

journal_volume

52

pub_type

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