Predictors of survival in patients with carcinoma of the gallbladder.

abstract：BACKGROUND:Although breast-conserving surgery was used with increasing frequency during the 1980s for management of breast cancer, most women still undergo mastectomy, and a substantial variation has been documented in the proportion of women receiving breast-conserving surgery across regions of the country. Using data...

journal_title：Cancer

authors： Samet JM,Hunt WC,Farrow DC

更新日期：1994-05-01 00:00:00

abstract：:Solitary plasmacytoma of bone (SPB) and extramedullary plasmacytoma (EMPC) are unusual solitary tumors of plasma cell origin. The clinical differences between these tumors and multiple myeloma are the subject of continued study. This review examines the radiotherapy experience at M. D. Anderson Hospital. Between 1948 ...

journal_title：Cancer

authors： Corwin J,Lindberg RD

更新日期：1979-03-01 00:00:00

abstract：:The cellular DNA content of 15 benign and 34 malignant primary bone tumors was analyzed by means of flow cytophotometry. All benign tumors except one of questionable histologic type exhibited a normal DNA content (diploid), whereas 23 of 34 malignant tumors showed an abnormal DNA content (aneuploid). Closer analysis r...

journal_title：Cancer

authors： Kreicbergs A,Silvferswärd C,Tribukait B

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Between January 11, 1991 and January 8, 1992, 104 patients with previously untreated, invasive, primitive breast carcinoma were admitted to the authors' hospital. METHODS:For each patient, flow cytometry DNA analyses on frozen samples and on immunohistochemical staining were performed, including Ki-67, cycl...

journal_title：Cancer

authors： Michels JJ,Duigou F,Marnay J,Henry-Amar M,Delozier T,Denoux Y,Chasle J

更新日期：2003-03-15 00:00:00

abstract：BACKGROUND:In spite of many reports, it remains unclear whether the presence of tumor cells in circulating blood flow predicts a poor prognosis. METHODS:Competitive seminested reverse transcriptase-polymerase chain reaction (RT-PCR), a technique for the quantitative detection of tumor cells, was applied to detect the ...

journal_title：Cancer

authors： Sadahiro S,Suzuki T,Tokunaga N,Yurimoto S,Yasuda S,Tajima T,Makuuchi H,Murayama C,Matsuda K

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:The polyamine system is a promising target for anticancer therapy. Ideally, an antineoplastic compound affecting this system should inhibit both ornithine decarboxylase and the polyamine transporter, and toxicity should be mild. Agmatine, decarboxylated L-arginine, appears to be such a compound. METHODS:Ade...

journal_title：Cancer

authors： Molderings GJ,Kribben B,Heinen A,Schröder D,Brüss M,Göthert M

更新日期：2004-08-15 00:00:00

abstract：:Between February 1980 and December 1985, splenectomies were performed in 13 patients with advanced (Stage III and IV) chronic lymphocytic leukemia (CLL). Patients had advanced disease for a median of 32 months at the time of splenectomy and all were refractory to chemotherapy. All patients were anemic with a median he...

journal_title：Cancer

authors： Stein RS,Weikert D,Reynolds V,Greer JP,Flexner JM

更新日期：1987-05-15 00:00:00

abstract：BACKGROUND:The objective of this Phase II study was to evaluate the concept of sequential chemotherapy in the treatment of patients with advanced nonsmall cell lung carcinoma (NSCLC) by the administration of carboplatin plus gemcitabine followed by of paclitaxel. METHODS:Patients with Stage IIIB (pleural effusion) or ...

journal_title：Cancer

authors： Edelman MJ,Gandara DR,Lau DH,Lara P,Lauder IJ,Tracy D

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Radiotherapy (RT) plays a major role in the management of hemangiopericytomas (HAP). The present analysis evaluates the role of precision RT in the management of HAP of the central nervous system (CNS) and represents one of the largest series of HAP treated with RT that can be found in the literature. METHO...

journal_title：Cancer

authors： Combs SE,Thilmann C,Debus J,Schulz-Ertner D

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Assessment of the responses of osteosarcoma patients to preoperative chemotherapy is of clinical importance. The purpose of this study was to estimate the accuracy of angiography and thallium-201 scintigraphy, compared with histology, in assessing the responses of patients with osteosarcoma to preoperative c...

journal_title：Cancer

authors： Kunisada T,Ozaki T,Kawai A,Sugihara S,Taguchi K,Inoue H

更新日期：1999-09-15 00:00:00

abstract：BACKGROUND:Cytotoxic analogs of somatostatin (SST), such as AN-238, which consists of 2-pyrrolinodoxorubicin (AN-201) linked to the SST carrier RC-121, can be targeted to tumors that express SST receptors. Because SST receptors are present in ovarian carcinoma cells, the authors evaluated the effect of AN-238 on the UC...

journal_title：Cancer

authors： Plonowski A,Schally AV,Koppan M,Nagy A,Arencibia JM,Csernus B,Halmos G

更新日期：2001-09-01 00:00:00

abstract：:Two cases of primary non-Hodgkin's lymphomas of the breast were studied with light and electron microscopy. By light microscopy, according to Rappaport's classification, one was a poorly differentiated lymphocytic lymphoma, the other a diffuse histiocytic lymphoma. However, the ultrastructural features of the latter w...

journal_title：Cancer

authors： Navas JJ,Battifora H

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Recently, the authors identified molecular signatures and pathways associated with nonsmall cell lung carcinoma histology and lung development. They hypothesized that genetic classifiers of histology would provide insight into lung tumorigenesis and would be associated with clinical outcome when evaluated in...

journal_title：Cancer

authors： Shah L,Walter KL,Borczuk AC,Kawut SM,Sonett JR,Gorenstein LA,Ginsburg ME,Steinglass KM,Powell CA

更新日期：2004-10-01 00:00:00

abstract：:Pretreatment biopsy material of 82 cases of follicular lymphoma of lymph node origin was reviewed. According to the amount of small lymphocytes in the parafollicular lymphoid tissue (PSL), tumors were classified: PSL++, abundant lymphocytes with prominent postcapillary venules; PSL+, a number of lymphocytes readily re...

journal_title：Cancer

authors： Ree HJ,Leone LA

更新日期：1978-04-01 00:00:00

abstract：:To evaluate the frequency, etiology, and outcome of diffuse interstitial pneumonitis after treatment of children with Stage IV (favorable histologic type) Wilms' tumor using whole-lung and abdominal radiation therapy, and combination chemotherapy, all cases reported in such patients entered on National Wilms' Tumor St...

journal_title：Cancer

authors： Green DM,Finklestein JZ,Tefft ME,Norkool P

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) have improved the outcome of patients with gastrointestinal stromal tumors (GISTs), but most patients eventually develop resistance and progress. Dasatinib is a potent inhibitor of BCR-ABL, KIT, and SRC family kinases as well as imatinib-resistant cells. In GISTs, response e...

journal_title：Cancer

authors： Montemurro M,Cioffi A,Dômont J,Rutkowski P,Roth AD,von Moos R,Inauen R,Toulmonde M,Burkhard RO,Knuesli C,Bauer S,Cassier P,Schwarb H,Le Cesne A,Koeberle D,Bärtschi D,Dietrich D,Biaggi C,Prior J,Leyvraz S

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Current research is inconclusive regarding the relation between alcohol consumption and prostate cancer risk. In this study, the authors examined the associations of total alcohol, type of alcoholic beverage, and drinking pattern with the risk of total, low-grade, and high-grade prostate cancer. METHODS:Dat...

journal_title：Cancer

authors： Gong Z,Kristal AR,Schenk JM,Tangen CM,Goodman PJ,Thompson IM

更新日期：2009-08-15 00:00:00

abstract：:Angioendotheliomatosis is a rare intravascular neoplastic process which has been presumed to be of endothelial origin. A 62-year-old woman had manifestations of this disorder which were initially localized to the nasal region, followed by fatal systemic dissemination. Electron microscopic examination of the neoplastic...

journal_title：Cancer

authors： Wick MR,Banks PM,McDonald TJ

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:This study analyzed whether proliferative activity and expression of P-glycoprotein 170 (P-170) or glutathione S-transferase-pi (GST-pi) in human non-small cell lung carcinomas (NSCLC) represent independent factors in resistance to doxorubicin or whether an association exists between these factors. METHODS:...

journal_title：Cancer

authors： Volm M,Mattern J,Samsel B

更新日期：1992-08-15 00:00:00

abstract：BACKGROUND:Tamoxifen is a prototypic cancer chemopreventive agent, yet clinical trials have not evaluated its effect on mortality or the impact of drug pricing on its cost-effectiveness. METHODS:A state-transition Markov model for a hypothetical cohort of women age 50 years was used to evaluate the effects of tamoxife...

journal_title：Cancer

authors： Melnikow J,Kuenneth C,Helms LJ,Barnato A,Kuppermann M,Birch S,Nuovo J

更新日期：2006-09-01 00:00:00

abstract：:Numerous examples exist of prognostic factors that have been conclusively established and that can segregate the target patient population into subgroups with vastly different outcomes. At the same time, we can expect, in the majority of trials being conducted, that if a new treatment turns out to be successful, it ge...

journal_title：Cancer

authors： Sather HN

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:The mortality of patients with colorectal carcinoma depends mainly upon subsequent liver metastasis even after curative operation. However, it is very difficult to predict the incidence of liver metastasis by analyzing conventional tumor markers or pathologic findings. In the current study, the authors exami...

journal_title：Cancer

authors： Kato M,Ito Y,Kobayashi S,Isono K

更新日期：1996-04-15 00:00:00

abstract：BACKGROUND:This case-referent study was conducted to elucidate the role of selected exogenous agents in the etiology of head and neck cancer. The factors studied were tobacco smoking, alcohol intake, the use of moist oral snuff, dietary factors, occupational exposures, and oral hygiene. In this first report, the author...

journal_title：Cancer

authors： Lewin F,Norell SE,Johansson H,Gustavsson P,Wennerberg J,Biörklund A,Rutqvist LE

更新日期：1998-04-01 00:00:00

abstract：:A humoral microcytotoxicity assay has been used to study the immune response to human malignant astrocytic tumors. Two series are described. When the assay was performed under uniform, ideal conditions, the sera from 36 of 45 patients with these tumors (80%) produced significant cytotoxicity against allogeneic astrocy...

journal_title：Cancer

authors： Wood WC,Kornblith PL,Quindlen EA,Pollock LA

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Natural killer (NK) cells are a group of effector cells that act nonspecifically against tumor cells. The correlation between intratumoral NK cell infiltration and clinicopathologic features remains unclear. METHODS:The authors selected 146 patients with gastric carcinoma who underwent gastrectomy at Kagosh...

journal_title：Cancer

authors： Ishigami S,Natsugoe S,Tokuda K,Nakajo A,Che X,Iwashige H,Aridome K,Hokita S,Aikou T

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:After surgical resection, the residual, invasive glioblastoma (GBM) cells give rise to a recurrent tumor, which, in 96% of patients, arises adjacent to the resection margin. METHODS:In this study, the authors prospectively enrolled 25 patients with GBM who underwent gross total resection followed by adjuvan...

journal_title：Cancer

authors： Mangiola A,de Bonis P,Maira G,Balducci M,Sica G,Lama G,Lauriola L,Anile C

更新日期：2008-08-15 00:00:00

abstract：BACKGROUND:Population-based studies suggest that, because of inequalities in treatment, black women with localized endometrial cancer have shorter survival compared with white women. The objective of the current investigation was to determine whether there is a racial disparity in outcome between black patients and whi...

journal_title：Cancer

authors： Maxwell GL,Tian C,Risinger JI,Hamilton CA,Barakat RR,Gynecologic Oncology Group Study.

更新日期：2008-09-15 00:00:00

abstract：:Characteristic alterations of marker enzymes and tumor-associated antigens have been detected in the preneoplastic lesions of experimental hepatocarcinogenesis. An identical pattern of enzyme activity (increased gammaglutamyl transferase, loss of glucose-6-phosphatase, and canalicular adenosine triphosphatase) was dem...

journal_title：Cancer

authors： Thung SN,Gerber MA

更新日期：1981-04-01 00:00:00

abstract：:This report documents, in seven infants younger than 2 years of age, a previously unrecognized association of a renal embryonal neoplasm (malignant rhabdoid tumor in six patients and a Wilms' tumor in one) with an embryonal primary tumor originating in the central nervous system. The neuroepithelial tumors included th...

journal_title：Cancer

authors： Bonnin JM,Rubinstein LJ,Palmer NF,Beckwith JB

更新日期：1984-11-15 00:00:00

abstract：:Conjugal tumors are rarely reported; but nevertheless, raise important questions of possible etiologic factors. In this report, the presentation of grade 2 gemistocytic astrocytomas in an unrelated married couple in their early thirties within 18 months of each other is described. In both cases the left frontal region...

journal_title：Cancer

authors： Tupchong L,Levison DA,Jones AE

更新日期：1985-02-15 00:00:00