Detection of DCC and Ki-ras gene alterations in colorectal carcinoma tissue as prognostic markers for liver metastatic recurrence.

abstract：BACKGROUND:Transitional cell carcinoma (TCC) of the bladder displays an unpredictable biologic behavior and the morphologic methods of grading tumor malignancy are often insufficient to predict the clinical outcome of patients with TCC of the bladder. Thus, the new indicator should reliably reflect prognosis. In this s...

journal_title：Cancer

authors： Shiina H,Igawa M,Nagami H,Yagi H,Urakami S,Yoneda T,Shirakawa H,Ishibe T,Kawanishi M

更新日期：1996-10-15 00:00:00

abstract：:The aims of this study were as follows: to confirm that the presence of estrogen (ER) and progesterone (PgR) receptors is an indicator of clinical behavior of human breast cancer independent of other known prognostic factors; to seek clinical correlates of those receptor values that best predict the overall disease ev...

journal_title：Cancer

authors： Vollenweider-Zerargui L,Barrelet L,Wong Y,Lemarchand-Béraud T,Gómez F

更新日期：1986-03-15 00:00:00

abstract：:Carcinoma of the breast is a disease that is associated with 10-year recurrence rates of 25% in operable patients with no spread to the axillary nodes and 75% in patients in whom the tumor has extended to the axillary nodes. Locoregional recurrence rates of close to 50% have been reported in patients with Stage III di...

journal_title：Cancer

authors： Marcial VA

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:In various neoplasms expression of the proliferation-related Ki-67 antigen has successfully been linked with parameters of progression of disease. While a definite grading scheme for oligodendrogliomas has still not been agreed upon, any parameter of tumor proliferation that might be helpful in predicting cl...

journal_title：Cancer

authors： Kros JM,Hop WC,Godschalk JJ,Krishnadath KK

更新日期：1996-09-01 00:00:00

abstract：:A case of basosquamous or so-called transitional cloacogenic carcinoma of the sigmoid colon, which arose above the pelvic brim at the peritoneal reflection, is reported. We were not able to find a report of this histologic type of tumor arising this far from the pectinate line of the anus, which is the most common pri...

journal_title：Cancer

authors： Strate RW,Richardson JD,Bannayan GA

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Disparities in treatment and mortality for colorectal cancer (CRC) may reflect differences in access to specialized care or other characteristics of the area where an individual lives. METHODS:Surveillance, Epidemiology and End Results Program-Medicare data for seniors diagnosed with CRC were linked to area...

journal_title：Cancer

authors： Haas JS,Brawarsky P,Iyer A,Fitzmaurice GM,Neville BA,Earle C

更新日期：2011-09-15 00:00:00

abstract：BACKGROUND:The therapeutic impact of tumor resection is poorly defined. Therefore the current study was conducted. METHODS:A retrospective, 2-institutional study was conducted (1991-1994) to compare the treatment results of stereotactic biopsy plus radiation therapy (99 patients; tumor dose: 60 gray [Gy]) with those o...

journal_title：Cancer

authors： Kreth FW,Berlis A,Spiropoulou V,Faist M,Scheremet R,Rossner R,Volk B,Ostertag CB

更新日期：1999-11-15 00:00:00

abstract：BACKGROUND:An open-label Phase II study of oxaliplatin was conducted to evaluate its safety and efficacy in children with recurrent or refractory medulloblastoma (MB), supratentorial primitive neuroectodermal tumors (SPNET), and atypical teratoid rhabdoid tumor (ATRT). METHODS:Patients were stratified as follows: stra...

journal_title：Cancer

authors： Fouladi M,Blaney SM,Poussaint TY,Freeman BB 3rd,McLendon R,Fuller C,Adesina AM,Hancock ML,Danks MK,Stewart C,Boyett JM,Gajjar A

更新日期：2006-11-01 00:00:00

abstract：:The body composition of 23 patients with cachexia resulting from malignant or benign inflammatory disease was studied. Skinfold thickness and radioisotope tracer measurements enabled us to estimate total body fat, lean body mass, the ratio of fat loss to lean body loss, erythrocyte and plasma volumes, total body water...

journal_title：Cancer

authors： Watson WS,Sammon AM

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Amplification of the N-myc oncogene is associated with adverse outcomes in the common childhood tumor, neuroblastoma. Because the transforming properties of Myc are related to its ability to modulate gene expression, the authors used cDNA microarrays to identify potential Myc target genes. METHODS:Expressio...

journal_title：Cancer

authors： Raetz EA,Kim MK,Moos P,Carlson M,Bruggers C,Hooper DK,Foot L,Liu T,Seeger R,Carroll WL

更新日期：2003-08-15 00:00:00

abstract：:Most patients with colorectal carcinoma undergo attempts at curative surgery. However, some present with metastatic disease and many others ultimately relapse. Most recurrences of colorectal cancer are not resectable and require nonsurgical approaches such as chemotherapy and radiation therapy directed against local r...

journal_title：Cancer

authors： Vaughn DJ,Haller DG

更新日期：1993-06-15 00:00:00

abstract：BACKGROUND:The objective of this study was to describe characteristics at diagnosis and outcomes of adults with soft tissue sarcoma. METHODS:The authors conducted a retrospective multicenter study of 12,262 patients who were treated between January 1980 and 31 December 2013 in French Sarcoma Group centers and enrolled...

journal_title：Cancer

authors： Penel N,Coindre JM,Giraud A,Terrier P,Ranchere-Vince D,Collin F,Guellec SLE,Bazille C,Lae M,de Pinieux G,Ray-Coquard IL,Bonvalot S,Cesne ALE,Robin YM,Stoeckle E,Toulmonde M,Blay JY

更新日期：2018-03-15 00:00:00

abstract：BACKGROUND:A higher total dose of radiation therapy administered in fractionated lower individual doses twice daily (hyperfractionated radiation therapy) has been reported to improve survival for children with brain stem gliomas. However, this higher dose of radiation therapy may cause more sequelae. METHOD:Eighty-eig...

journal_title：Cancer

authors： Packer RJ,Zimmerman RA,Kaplan A,Wara WM,Rorke LB,Selch M,Goldwein J,Allen JA,Boyett J,Albright AL

更新日期：1993-04-15 00:00:00

abstract：BACKGROUND:Breast cancer is the second most common source of brain metastasis. Stereotactic radiosurgery (SRS) can be an effective treatment for some patients with brain metastasis (BM). Necrosis is a common feature of many brain tumors, including BM; however, the influence of tumor necrosis on treatment efficacy of SR...

journal_title：Cancer

authors： Xu Z,Marko NF,Angelov L,Barnett GH,Chao ST,Vogelbaum MA,Suh JH,Weil RJ

更新日期：2012-03-01 00:00:00

abstract：:The clinical, morphologic, and immunohistochemical features of 5 cases of peripheral T-cell lymphoma with lymph node and skin involvement are reported. All patients were male and presented with generalized lymphadenopathy and skin lesions. Lymph node biopsy specimens showed a diffusely growing, pleomorphic, atypical l...

journal_title：Cancer

authors： van den Oord JJ,De Wolf-Peeters C,Frizzera G,Desmet VJ,Tricot G,Thomas J,Marien K,Gatter KC,Mason DY

更新日期：1985-04-15 00:00:00

abstract：BACKGROUND:There is significant need for quality follow-up care to optimize long-term outcomes for the growing population of lower gastrointestinal (GI) cancer survivors. Patient-reported outcomes (PROs) provide valuable information regarding late and long-term effects (LLTEs). METHODS:A convenience sample from 1129 c...

journal_title：Cancer

authors： Frick MA,Vachani CC,Hampshire MK,Bach C,Arnold-Korzeniowski K,Metz JM,Hill-Kayser CE

更新日期：2017-05-15 00:00:00

abstract：:The use of molecular techniques in cytopathology has become an accepted and billable practice for certain applications. Other applications still are in the developmental or experimental stages but may soon be clinically useful. The current study provides a review of these techniques including molecular detection of cl...

journal_title：Cancer

authors： Rimm DL

更新日期：2000-02-25 00:00:00

abstract：:The American Joint Committee on Cancer proposes the following criteria for evaluating putative prognostic factors: they must be (1) significant, (2) independent, and (3) clinically important. Furthermore, we suggest the criteria for selecting a prognostic system that includes TNM and new prognostic factors. These crit...

journal_title：Cancer

authors： Burke HB,Henson DE

更新日期：1993-11-15 00:00:00

abstract：BACKGROUND:We have often encountered difficulties in identifying small liver cancers during surgery. Fluorescent imaging using indocyanine green (ICG) has the potential to detect liver cancers through the visualization of the disordered biliary excretion of ICG in cancer tissues and noncancerous liver tissues compresse...

journal_title：Cancer

authors： Ishizawa T,Fukushima N,Shibahara J,Masuda K,Tamura S,Aoki T,Hasegawa K,Beck Y,Fukayama M,Kokudo N

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:A sedentary life style has been consistently associated with an increased risk of colon cancer, but the evidence for its association with breast and other gynecologic cancers is limited. METHODS:Occupational information for 3783 incident patients with cancer (breast, 2736; corpus uteri, 452; and ovary, 595)...

journal_title：Cancer

authors： Zheng W,Shu XO,McLaughlin JK,Chow WH,Gao YT,Blot WJ

更新日期：1993-06-01 00:00:00

abstract：:Kaposi's sarcoma developed in two lymphoma patients previously treated by chemotherapy and chemoirradiation. The histologic picture in the two cases showed a non-Hodgkin's lymphoma with multifocal epithelioid histiocytic reaction. Both patients had Hepatitis-B surface antigen and other infections due to herpes and str...

journal_title：Cancer

authors： Berrebi A,Shtalrid M,Hurwitz N,Frumkin A,Schattner A

更新日期：1984-08-15 00:00:00

abstract：:The effect of cyclophosphamide (CY) on ovarian function was studied in patients with breast cancer receiving prolonged daily administration of this agent (100 mg/day) after radical surgery. Out of 18 premenopausal patients that received 8.4-39.9 g CY, 15 developed permanent amenorrhea. The average dose given before th...

journal_title：Cancer

authors： Koyama H,Wada T,Nishizawa Y,Iwanaga T,Aoki Y

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:During a population-based local cancer registry, a peculiar type of T-cell lymphoma restricted to the gastrointestinal tract was found in patients living in southwestern Japan. METHODS:Five cases of gastrointestinal (GI) tract T-cell lymphoma were analyzed with immunohistologic examination, ultrastructural ...

journal_title：Cancer

authors： Tokunaga O,Watanabe T,Shimamoto Y,Tokudome S

更新日期：1993-02-01 00:00:00

abstract：:The clinicopathologic features of 60 patients with thymic carcinoma were studied. Patients ranged in age from 10 to 76 years (mean, 46), of whom 24 were females and 36 were males. Overall survival at 1, 3, and 5 years was 56.6%, 40%, and 33.3%, respectively. The following morphologic features were correlated with surv...

journal_title：Cancer

authors： Suster S,Rosai J

更新日期：1991-02-15 00:00:00

abstract：:Light microscopic, immunocytochemical and ultrastructural studies were performed on chondrosarcomas which contained a second, noncartilagenous mesenchymal component. Attention was focused on the nonchondroid portion of each tumor in an attempt to elucidate the histogenesis of this mixed variant of chondrosarcoma. The ...

journal_title：Cancer

authors： Têtu B,Ordóñez NG,Ayala AG,Mackay B

更新日期：1986-07-15 00:00:00

abstract：:The authors reviewed clinical features, surgical extent of resection, histologic parameters, and DNA content in 55 children with medulloblastomas and found that complete or near total resection, absence of tumor dissemination, tumor DNA aneuploidy, and low proliferative index correlated with a favorable clinical outco...

journal_title：Cancer

authors： Schofield DE,Yunis EJ,Geyer JR,Albright AL,Berger MS,Taylor SR

更新日期：1992-03-01 00:00:00

abstract：:In a 10-year incidence survey of breast cancer in the City of Boston, 14 cases in American Chinese women were observed, while approximately 13 were expected on the basis of age-specific incidence in the white population. In Hawaii, on the other hand, while breast cancer incidence rates for ethnic Chinese are approxima...

journal_title：Cancer

authors： Trichopoulos D,Yen S,Brown J,Cole P,MacMahon B

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Telomerase activity and telomere length have been shown to be involved in the control of cell proliferation and regulation of cell senescence. The expression of telomerase activity may endow cells with the capacity of unlimited proliferation and immortality. The authors examined the telomerase activity and t...

journal_title：Cancer

authors： Chen HJ,Liang CL,Lu K,Lin JW,Cho CL

更新日期：2000-11-15 00:00:00

abstract：BACKGROUND:Although aging is one of the most important risk factors for cancer, elderly patients tend to be excluded from cancer clinical trials, only on the basis of chronologic age. Performance Status (PS) has been used widely to select adult patients for entry into clinical trials, but it does not include a comprehe...

journal_title：Cancer

authors： Monfardini S,Ferrucci L,Fratino L,del Lungo I,Serraino D,Zagonel V

更新日期：1996-01-15 00:00:00

abstract：BACKGROUND:The treatment of advanced, inoperable, or recurrent parotid tumors represents a clinical challenge. The results obtained with conventional radiotherapy are disappointing. To improve the early response and local control of parotid tumors, local microwave hyperthermia was used in combination with ionizing radi...

journal_title：Cancer

authors： Gabriele P,Amichetti M,Orecchia R,Valdagni R

更新日期：1995-02-15 00:00:00